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Volumn 8, Issue 2, 2008, Pages 60-63

Rear-view mirrors and crystal balls: A brief reflection on drug discovery

Author keywords

[No Author keywords available]

Indexed keywords

DRUG DELIVERY SYSTEM; DRUG RESEARCH; DRUG TARGETING; EDITORIAL; MEDICAL RESEARCH; PHARMACOLOGY;

EID: 42249096582     PISSN: 15340384     EISSN: 15432548     Source Type: Journal    
DOI: 10.1124/mi.8.2.1     Document Type: Editorial
Times cited : (5)

References (12)
  • 1
    • 0034677966 scopus 로고    scopus 로고
    • Drug discovery: A historical perspective
    • Drews, J. Drug discovery: A historical perspective. Science 287, 1960-1964 (2000).
    • (2000) Science , vol.287 , pp. 1960-1964
    • Drews, J.1
  • 2
    • 26044482076 scopus 로고    scopus 로고
    • Case history: The discovery of fluoxetine hydrochloride (Prozac)
    • Wong, D.T., Perry, K.W., and Bymaster, F.P. Case history: The discovery of fluoxetine hydrochloride (Prozac). Nature Rev. Drug Discov. 4, 764-774 (2005).
    • (2005) Nature Rev. Drug Discov , vol.4 , pp. 764-774
    • Wong, D.T.1    Perry, K.W.2    Bymaster, F.P.3
  • 3
    • 29144536779 scopus 로고    scopus 로고
    • Life cycle of a block buster drug: Discovery and development of omeprazole (Prilosec)
    • Berkowitz, B.A. and Sachs, G. Life cycle of a block buster drug: Discovery and development of omeprazole (Prilosec). Mol. Interv. 2, 6-11 (2002).
    • (2002) Mol. Interv , vol.2 , pp. 6-11
    • Berkowitz, B.A.1    Sachs, G.2
  • 4
    • 37549019221 scopus 로고    scopus 로고
    • Rubin, R.P. A brief history of great discoveries in pharmacology: In celebration of the centennial anniversary of the founding of the American Society of Pharmacology and Experimental Therapeutics
    • Rubin, R.P. A brief history of great discoveries in pharmacology: In celebration of the centennial anniversary of the founding of the American Society of Pharmacology and Experimental Therapeutics. Pharmacol. Rev. 59, 289-359 (2007).
    • (2007) Pharmacol. Rev , vol.59 , pp. 289-359
  • 5
    • 33644504461 scopus 로고    scopus 로고
    • Antibacterial drug discovery. Then, now and the genomics future
    • Monaghan, R.L. and Barrett, J.F. Antibacterial drug discovery. Then, now and the genomics future. Biochem. Pharmacol. 71, 901-909 (2005).
    • (2005) Biochem. Pharmacol , vol.71 , pp. 901-909
    • Monaghan, R.L.1    Barrett, J.F.2
  • 6
    • 33947596504 scopus 로고    scopus 로고
    • Why is cancer drug discovery so difficult?
    • Kamb, A., Wee, S., and Lengauer, C. Why is cancer drug discovery so difficult? Nature Rev. Drug Discov. 6, 115-120 (2007).
    • (2007) Nature Rev. Drug Discov , vol.6 , pp. 115-120
    • Kamb, A.1    Wee, S.2    Lengauer, C.3
  • 7
    • 4344645978 scopus 로고    scopus 로고
    • Can the pharmaceutical industry reduce attrition rates?
    • Kola, I., and Landis, J. Can the pharmaceutical industry reduce attrition rates? Nature Rev. Drug Discov. 3, 711-715 (2004).
    • (2004) Nature Rev. Drug Discov , vol.3 , pp. 711-715
    • Kola, I.1    Landis, J.2
  • 8
    • 0343262714 scopus 로고    scopus 로고
    • Choosing anticancer drug targets in the postgenomic era
    • Kaelin, Jr, W.G. Choosing anticancer drug targets in the postgenomic era. J. Clin. Invest. 104, 1503-1506 (1999).
    • (1999) J. Clin. Invest , vol.104 , pp. 1503-1506
    • Kaelin Jr, W.G.1
  • 9
    • 0033601370 scopus 로고    scopus 로고
    • Pharmacological rescue of mutant p53 conformation and function
    • Foster, B.A., Coffey, H.A., Morin, M.J., and Rastinejad, F. Pharmacological rescue of mutant p53 conformation and function. Science 286, 2507-2510 (1999).
    • (1999) Science , vol.286 , pp. 2507-2510
    • Foster, B.A.1    Coffey, H.A.2    Morin, M.J.3    Rastinejad, F.4
  • 10
  • 11
    • 33847308224 scopus 로고    scopus 로고
    • Inhibiting transient protein-protein interactions: Lessons from the Cdc25 protein tyrosine phosphatases
    • Rudolph, J. Inhibiting transient protein-protein interactions: Lessons from the Cdc25 protein tyrosine phosphatases. Nature Rev. Cancer 7, 202-211 (2007).
    • (2007) Nature Rev. Cancer , vol.7 , pp. 202-211
    • Rudolph, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.