Interaction of a cyclostreptin analogue with the microtubule taxoid site: The covalent reaction rapidly follows binding

Journal of Natural Products

Volumn 71, Issue 3, 2008, Pages 370-374

  Bai, Ruoli ^a   Vanderwal, Christopher D ^b   Díaz, J Fernando ^c   Hamel, Ernest ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

8 ACETYLCYCLOSTREPTIN; 8 ACETYLCYCLOSTREPTIN ACETYL C14; ALDEHYDE; ASPARAGINE; BETA TUBULIN; CYCLOSTREPTIN; GUTARALDEHYDE; PACLITAXEL; RADIOISOTOPE; TAXOID; THREONINE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CHEMICAL REACTION; ENERGY; ISOTOPE LABELING; KINETICS; MICROTUBULE; NUCLEOTIDE SEQUENCE; POLYMERIZATION; PROTEIN ASSEMBLY; STOICHIOMETRY;

ASPARAGINE; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; MICROTUBULES; MOLECULAR STRUCTURE; POLYCYCLIC COMPOUNDS; TAXOIDS; THREONINE; TUBULIN; TUBULIN MODULATORS;

EID: 42249096447     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np800056m     Document Type: Article

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