Association of TP53 gene polymorphisms with genetic susceptibility to liver metastases of colorectal cancer

Chinese Journal of Medical Genetics

Volumn 25, Issue 2, 2008, Pages 168-171

  Wang, Ai Zhong ^a   Zhu, Zhong Zheng ^a   Cong, Wen Ming ^b   Jia, Hang Ruo ^a   Jin, Xia Xiang ^a   He, Xiang Lei ^c   Zhu, Guan Shan ^d  

^a No 113 Hospital of People's Liberation Army   (China)

^b SECOND MILITARY MEDICAL UNIVERSITY   (China)

^c Lihuili Hospital   (China)

^d Shanghai GenePharma Co Ltd   (China)

Author keywords

Colorectal cancer; Genetic susceptibility; Liver metastases; P53 expression; Single nucleotide polymorphism; TP53 gene

Indexed keywords

PARAFFIN; PROTEIN P53;

ALLELE; ARTICLE; ASSAY; CANCER PATIENT; CANCER RISK; CHINESE; COLORECTAL CANCER; COMPARATIVE STUDY; CONFIDENCE INTERVAL; CONTROLLED STUDY; DNA POLYMORPHISM; FEMALE; GENE; GENETIC SUSCEPTIBILITY; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER METASTASIS; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; POPULATION; PROTEIN EXPRESSION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK; RISK FACTOR; SEX; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; AGED, 80 AND OVER; COLORECTAL NEOPLASMS; FEMALE; GENES, P53; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LIVER NEOPLASMS; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH;

EID: 42249091732     PISSN: 10039406     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Manfredi S, Lepage C, Hatem C, et al. Epidemiology and management of liver metastases from colorectal cancer. Ann Surg, 2006, 244:254-259.
2. Adachi Y, Inomata M, Kakisako K, et al. Histopathologic characteristics of colorectal cancer with liver metastasis. Dis Colon Rectum, 1999, 42:1053-1056.
3. Chang HJ, Lee MR, Hong SH, et al. Identification of mitochondrial F(0) F(1)-ATP synthase involved in liver metastasis of colorectal cancer. Cancer Sci, 2007, 98:1184-1191.
4. Ghadjar P, Coupland SE, Na IK, et al. Chemokine receptor CCR6 expression level and liver metastases in colorectal cancer. J Clin Oncol, 2006, 24:1910-1916.
5. Kosaka Y, Mimori K, Tanaka F, et al. Clinical significance of the loss of MATS1 mRNA expression in colorectal cancer. Int J Oncol, 2007, 31:333-338.
6. Kastrinakis WV, Ramchurren N, Rieger KM, et al. Increased incidence of P53 mutations is associated with hepatic metastasis in colorectal neoplastic progression. Oncogene, 1995, 11:647-652.
7. Kang SM, Maeda K, Onoda N, et al. Combined analysis of P53 and vascular endothelial growth factor expression in colorectal carcinoma for determination of tumor vascularity and liver metastasis. Int J Cancer, 1997, 74:502-507.
8. Liang JT, Huang KC, Jeng YM, et al. Microvessel density, cyclo-oxygenase 2 expression, K-ras mutation and P53 overexpression in colonic cancer. Br J Surg, 2004, 91:355-361.
9. Dameron KM, Volpert OV, Tainsky MA, et al. Control of angiogenesis in fibroblasts by P53 regulation of thrombospondin-1. Science, 1994, 265:1582-1584.
10. Kieser A, Weich HA, Brandner G, et al. Mutant P53 potentiates protein kinase C induction of vascular endothelial growth factor expression. Oncogene, 1994, 9:963-969.
11. Zhu ZZ, Cong WM, Zhu GS, et al. Association of P53 codon 72 polymorphism with genetic susceptibility to hepatocellular carcinoma in Chinese population. Chin J Med Genet, 2005, 22:632-635.
12. Brooks LA, Tidy JA, Gusterson B, et al. Preferential retention of codon 72 arginine P53 in squamous cell carcinomas of the vulva occurs in cancers positive and negative for human papillomavirus. Cancer Res, 2000, 60:6875-6877.
13. Zhu ZZ, Wang AZ, Jia HR, et al. Association of the TP53 codon 72 polymorphism with colorectal cancer in a Chinese population. Jpn J Clin Oncol, 2007, 37:385-390.
14. Schneider-Stock R, Boltze C, Peters B, et al. Selective loss of codon 72 proline P53 and frequent mutational inactivation of the retained arginine allele in colorectal cancer. Neoplasia, 2004, 6:529-535.
15. Lee JM, Shun CT, Wu MT, et al. The associations of P53 overexpression with P53 codon 72 genetic polymorphism in esophageal cancer. Mutat Res, 2006, 594:181-188.
16. Marin MC, Jost CA, Brooks LA, et al. A common polymorphism acts as an intragenic modifier of mutant P53 behaviour. Nat Genet, 2000, 25:47-54.