Effects of fentanyl on gastric myoelectrical activity: A possible association with polymorphisms of the μ-opioid receptor gene?

Acta Anaesthesiologica Scandinavica

Volumn 52, Issue 5, 2008, Pages 708-715

  Wallden J ^a,b   Lindberg, G ^c   Sandin, M ^d   Thorn S E ^b,d   Wattwil, M ^b,d  

^a SUNDSVALL HOSPITAL   (Sweden)

^b ÖREBRO UNIVERSITY   (Sweden)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^d ÖREBRO UNIVERSITY HOSPITAL   (Sweden)

Author keywords

*genetics; Analgesics; Electrogastrography; Gastric myoelectrical activity; Gastrointestinal motility; Genotype; Opioid; Opioid receptors; Single nucleotide polymorphism

Indexed keywords

FENTANYL; MU OPIATE RECEPTOR;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CORRELATION ANALYSIS; ELECTIVE SURGERY; ELECTROGASTROGRAPHY; FEMALE; GASTRIC DYSMOTILITY; GENE; GENETIC ANALYSIS; HUMAN; MALE; MU OPIOID RECEPTOR GENE; MYOELECTRICITY; OUTCOME ASSESSMENT; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; STOMACH EMPTYING; WAVEFORM;

ADULT; AGED; ANALGESICS, OPIOID; ELECTROPHYSIOLOGY; FEMALE; FENTANYL; GASTROINTESTINAL MOTILITY; GENOTYPE; HUMANS; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; POSTOPERATIVE NAUSEA AND VOMITING; RECEPTORS, OPIOID, MU; STOMACH;

EID: 42249085759     PISSN: 00015172     EISSN: 13996576     Source Type: Journal    
DOI: 10.1111/j.1399-6576.2008.01624.x     Document Type: Article

References (28)

1. Sanders KM, Ördög T, Koh SD et al. Properties of electrical rhytmicity in the stomach. In : Koch KL, Stern RM, eds. Handbook of electrogastrography. New York : Oxford University Press, 2004 : 13 36.
2. Chang FY. Electrogastrography: basic knowledge, recording, processing and its clinical applications. J Gastroenterol Hepatol 2005 20 (4) : 502 16.
3. Hicks GA, DeHaven-Hudkins DL, Camilleri M. Opiates in the control of gastrointestinal tract function: current knowledge and new avenues for research. Neurogastroenterol Motil 2004 16 (Suppl. 2) : 67 70.
4. Thorn SE, Wattwil M, Lindberg G et al. Systemic and central effects of morphine on gastroduodenal motility. Acta Anaesthesiol Scand 1996 40 (2) : 177 86.
5. Coulbault L, Beaussier M, Verstuyft C et al. Environmental and genetic factors associated with morphine response in the postoperative period. Clin Pharmacol Ther 2006 79 (4) : 316 24.
6. Klepstad P, Rakvag TT, Kaasa S et al. The 118 A>G polymorphism in the human micro-opioid receptor gene may increase morphine requirements in patients with pain caused by malignant disease. Acta Anaesthesiol Scand 2004 48 (10) : 1232 9.
7. Simonian HP, Panganamamula K, Parkman HP et al. Multichannel electrogastrography (EGG) in normal subjects: a multicenter study. Dig Dis Sci 2004 49 (4) : 594 601.
8. Shibutani K, Inchiosa MA Jr., Sawada K et al. Accuracy of pharmacokinetic models for predicting plasma fentanyl concentrations in lean and obese surgical patients: derivation of dosing weight ("pharmacokinetic mass"). Anesthesiology 2004 101 (3) : 603 13.
9. Shafer SL, Varvel JR, Aziz N et al. Pharmacokinetics of fentanyl administered by computer-controlled infusion pump. Anesthesiology 1990 73 (6) : 1091 102.
10. Ikeda K, Ide S, Han W et al. How individual sensitivity to opiates can be predicted by gene analyses. Trends Pharmacol Sci 2005 26 (6) : 311 7.
11. Belfer I, Wu T, Kingman A et al. Candidate gene studies of human pain mechanisms: methods for optimizing choice of polymorphisms and sample size. Anesthesiology 2004 100 (6) : 1562 72.
12. Wallden J, Thorn SE, Wattwil M. The delay of gastric emptying induced by remifentanil is not influenced by posture. Anesth Analg 2004 99 (2) : 429 34.
13. Nimmo WS, Heading RC, Wilson J et al. Inhibition of gastric emptying and drug absorption by narcotic analgesics. Br J Clin Pharmacol 1975 2 (6) : 509 13.
14. Yuan CS, Foss JF, O'Connor M et al. Effects of low-dose morphine on gastric emptying in healthy volunteers. J Clin Pharmacol 1998 38 (11) : 1017 20.
15. Lewis TD. Morphine and gastroduodenal motility. Dig Dis Sci 1999 44 (11) : 2178 86.
16. Edin R, Lundberg J, Terenius L et al. Evidence for vagal enkephalinergic neural control of the feline pylorus and stomach. Gastroenterology 1980 78 (3) : 492 7.
17. Hammas B, Thorn SE, Wattwil M. Propofol and gastric effects of morphine. Acta Anaesthesiol Scand 2001 45 (8) : 1023 7.
18. Penagini R, Allocca M, Cantu P et al. Relationship between motor function of the proximal stomach and transient lower oesophageal sphincter relaxation after morphine. Gut 2004 53 (9) : 1227 31.
19. Bitar KN, Makhlouf GM. Specific opiate receptors on isolated mammalian gastric smooth muscle cells. Nature 1982 297 (5861) : 72 4.
20. De Schepper HU, Cremonini F, Park MI et al. Opioids and the gut: pharmacology and current clinical experience. Neurogastroenterol Motil 2004 16 (4) : 383 94.
21. Aicher SA, Mitchell JL, Mendelowitz D. Distribution of mu-opioid receptors in rat visceral premotor neurons. Neuroscience 2002 115 (3) : 851 60.
22. Browning KN, Kalyuzhny AE, Travagli RA. Opioid peptides inhibit excitatory but not inhibitory synaptic transmission in the rat dorsal motor nucleus of the vagus. J Neurosci 2002 22 (8) : 2998 3004.
23. Telford GL, Hoshmonai M, Moses AJ et al. Morphine initiates migrating myoelectric complexes by acting on peripheral opioid receptors. Am J Physiol 1985 249 (5, Part 1) : G557 62.
24. Thorn SE, Wickbom G, Philipson L et al. Myoelectric activity in the stomach and duodenum after epidural administration of morphine or bupivacaine. Acta Anaesthesiol Scand 1996 40 (7) : 773 8.
25. Qian LW, Pasricha PJ, Chen JD. Origins and patterns of spontaneous and drug-induced canine gastric myoelectrical dysrhythmia. Dig Dis Sci 2003 48 (3) : 508 15.
26. Klepstad P, Dale O, Skorpen F et al. Genetic variability and clinical efficacy of morphine. Acta Anaesthesiol Scand 2005 49 (7) : 902 8.
27. Chou WY, Yang LC, Lu HF et al. Association of mu-opioid receptor gene polymorphism (A118G) with variations in morphine consumption for analgesia after total knee arthroplasty. Acta Anaesthesiol Scand 2006 50 (7) : 787 92.
28. Mikus G, Trausch B, Rodewald C et al. Effect of codeine on gastrointestinal motility in relation to CYP2D6 phenotype. Clin Pharmacol Ther 1997 61 (4) : 459 66.