Accuracy of pharmacokinetic models for predicting plasma fentanyl concentrations in lean and obese surgical patients: Derivation of dosing weight ("pharmacokinetic mass")

Anesthesiology

Volumn 101, Issue 3, 2004, Pages 603-613

  Shibutani, Kinichi ^a   Inchiosa Jr , Mario A ^a   Sawada, Keisuke ^b   Bairamian, Mosses ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b NAGOYA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ATRACURIUM; FENTANYL; PROPOFOL; SEVOFLURANE;

ABDOMINAL SURGERY; ACCURACY; ADULT; AGED; ARTICLE; BODY MASS; BODY WEIGHT; COMPUTER SIMULATION; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; DRUG BLOOD LEVEL; DRUG CLEARANCE; ELECTIVE SURGERY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MODEL; NONLINEAR REGRESSION ANALYSIS; OBESITY; ORTHOPEDIC SURGERY; PHARMACOKINETIC MODEL; POSTOPERATIVE ANALGESIA; POSTOPERATIVE PAIN; PREDICTION; PRIORITY JOURNAL; RADIOIMMUNOASSAY; SURGICAL PATIENT; THORAX SURGERY; VASCULAR SURGERY;

EID: 4344639444     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-200409000-00008     Document Type: Article

References (16)

1. Shafer SL, Varvel JR, Aziz N, Scott JC: Pharmacokinetics of fentanyl administered by computer-controlled infusion pump. ANESTHESIOLOGY 1990; 73:1091-102
2. Glass PSA, Reves JG: Drug delivery system to improve the perioperative administration of intravenous drugs: Computer Assisted Continuous Infusion (CACI). Anesth Analg 1995; 81:665-7
3. Glass PSA, Jacobs JR, Smith LR, Ginsberg B, Quill TJ, Bai SA, Reves JG: Pharmacokinetic model-driven infusion of fentanyl: Assessment of accuracy. ANESTHESIOLOGY 1990; 73:1082-90
4. Scott JC, Stanski DR: Decreased fentanyl and alfentanil dose requirement with age: A simultaneous pharmacokinetic and pharmacodynamic evaluation. J Pharmacol Exp Ther 1987; 240:159-66
5. Bouillon T, Shafer SL: Does size matter? ANESTHESIOLOGY 1998; 89:557-60
6. Morgan DJ, Bray KM: Lean body mass as a predictor of drug dosage: Implementation for drug therapy. Clin. Pharmacokinet 1994; 26:292-307
7. Slepchenko G, Simon N, Goubaux B, Levron JC, Le Moing JP, Raucoules-Aime M: Performance of target-controlled sufentanil infusion in obese patients. ANESTHESIOLOGY 2003: 98:65-73
8. Agarwal N, Shibutani K, SanFilippo JA, Del Guercio LRM: Hemodynamic and respiratory changes in surgery of the morbidly obese. Surgery 1982; 92:220-34
9. Wada DR, Bjorkman S, Ebling WF, Harashima H, Harapat SR, Stanski DR: Computer simulation of the effects of alterations in blood flows and body composition on thiopental pharmacokinetics in humans. ANESTHESIOLOGY 1997; 87:884-99
10. Bjorkman S, Wada DR, Stanski DR: Application of physiologic models to predict the influence of changes in body composition and blood flows on the pharmacokinetics of fentanyl and alfentanil in patients. ANESTHESIOLOGY 1998: 88:657-07
11. Henthorn TK, Krejcie TC, and Avram MJ The relationship between alfentanil distribution kinetics and cardiac output. Clin Pharmacol Ther 1992; 52:190-6
12. Maitre PO, Vozeh S, Heykants G, Thomson DA, Stanski DR: Population pharmacokinetics of alfentanil: The average dose-plasma concentration relationship and interindividual variability in patients. ANESTHESIOLOGY 1987; 66:3-12
13. Schwartz AE, Matteo RS, Ornstein E, Young WL, Meyers KJ: Pharmacokinetics of sufentanil in obese patients. Anesth Analg 1991; 73:790-3
14. Egan TD, Huizinga B, Gupta SK, Jaarsma RL, Sperry RJ, Yee JB, Muir KT: Remifentanil pharmacokinetics in obese versus lean patients. ANESTHESIOLOGY 1998; 89:562-73
15. Shafer SL, Varvel, JR: Pharmacokinetics, pharmacodynamics, and rational opioid selection. ANESTHESIOLOGY 1991; 74:53-63
16. Hughes MA, Glass PSA, Jacobs JR: Context-sensitive half-time in multicompartment pharmacokinetic models for intravenous anesthetic drugs. ANESTHESIOLOGY 1992; 76:334-41