Mechanistic study of potentiation of chemotherapy by a haloenol lactone derivative in vitro

Cancer Chemotherapy and Pharmacology

Volumn 62, Issue 1, 2008, Pages 117-122

  Wang, Wei ^a   Xia, Cindy Q ^b   Liu, Ning ^b   Gan, Liang Shang ^c   Zheng, Jiang ^a,d  

^a NORTHEASTERN UNIVERSITY   (United States)

^b MILLENNIUM PHARMACEUTICALS INC   (United States)

^c BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

^d UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

GST selective inhibitor; Haloenol lactone; MRP inhibition; Potentiation in drug resistance

Indexed keywords

3 CINNAMYL 5 BROMOMETHYLIDENETETRAHYDRO 2 FURANONE; CHLORAMBUCIL; CISPLATIN; GLUTATHIONE; GLUTATHIONE TRANSFERASE P1; LACTONE DERIVATIVE; MELPHALAN; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 2; MULTIDRUG RESISTANCE PROTEIN 3; UNCLASSIFIED DRUG; VERLUKAST;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENTIATION; GLUTATHIONE METABOLISM; HUMAN; HUMAN CELL; IC 50; KIDNEY CARCINOMA; PRIORITY JOURNAL;

4-BUTYROLACTONE; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC AGENTS, ALKYLATING; CELL LINE, TUMOR; CELL SURVIVAL; CISPLATIN; DRUG RESISTANCE, NEOPLASM; DRUG SYNERGISM; ESTRADIOL; GLUTATHIONE; GLUTATHIONE S-TRANSFERASE PI; HUMANS; LEUKOTRIENE C4; MEMBRANES; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS;

EID: 42149177817     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-007-0581-x     Document Type: Article

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