Modeling atopic dermatitis with increasingly complex mouse models

Journal of Investigative Dermatology

Volumn 128, Issue 5, 2008, Pages 1061-1064

  Scharschmidt, Tiffany C ^a   Segre, Julia A ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN C1;

ATOPIC DERMATITIS; DISEASE SEVERITY; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; INNATE IMMUNITY; KERATINOCYTE; NONHUMAN; NOTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; UNITED STATES;

EID: 42149172649     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/sj.jid.5701201     Document Type: Note

References (12)

1. Aberg KM, Man M-Q, Gallo RL, Ganz T, Crumrine D, Brown BE et al. (2007) Co-regulation and interdependence of the mammalian epidermal permeability and antimicrobial barriers. J Invest Dermatol, published online 18 October 2007; doi:10.1038/sj.jid.5701099
2. Bickers DR, Lim HW, Margolis D, Weinstock MA, Goodman C, Faulkner E et al. (2006) The burden of skin diseases, 2004: a joint project of the American Academy of Dermatology Association and the Society for Investigative Dermatology. J Am Acad Dermatol 55:490-500
3. Elias PM, Feingold KR (2001) Does the tail wag the dog? Role of the barrier in the pathogenesis of inflammatory dermatoses and therapeutic implications. Arch Dermatol 137:1079-81
4. Epp N, Furstenberger G, Muller K, de Juanes S, Leitges M, Hausser I et al. (2007) 12R-lipoxygenase deficiency disrupts epidermal barrier function. J Cell Biol 177:173-82
5. Howell MD, Kim BE, Gao P, Grant AV, Boguniewicz M, Debenedetto A et al. (2007) Cytokine modulation of atopic dermatitis filaggrin skin expression. J Allergy Clin Immunol 120:150-5
6. Man M-Q, Hatano Y, Lee SH, Man M, Chang S, Feingold KR et al. (2008) Characterization of a hapten-induced, murine model with multiple features of atopic dermatitis: structural, immunologic, and biochemical changes following single versus multiple oxazolone challenges. J Invest Dermatol 128:79-86
7. Nagelkerken L, Verzaal P, Lagerweij T, Persoon-Deen C, Berbee JF, Prens EP et al. (2008) Development of atopic dermatitis in mice transgenic for human apolipoprotein C1. J Invest Dermatol 128:1165-72
8. Presland RB, Boggess D, Lewis SP, Hull C, Fleckman P, Sundberg JP (2000) Loss of normal profilaggrin and filaggrin in flaky tail (ft/ft) mice: an animal model for the filaggrin-deficient skin disease ichthyosis vulgaris. J Invest Dermatol 115:1072-81
9. Sandilands A, Terron-Kwiatkowski A, Hull PR, O'Regan GM, Clayton TH, Watson RM et al. (2007) Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema. Nat Genet 39:650-4
10. Soumelis V, Reche PA, Kanzler H, Yuan W, Edward G, Homey B et al. (2002) Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP. Nat Immunol 3:673-80
11. Terada M, Tsutsui H, Imai Y, Yasuda K, Mizutani H, Yamanishi K et al. (2006) Contribution of IL-18 to atopic-dermatitis-like skin inflammation induced by Staphylococcus aureus product in mice. Proc Natl Acad Sci USA 103:8816-21
12. Yoo J, Omori M, Gyarmati D, Zhou B, Aye T, Brewer A et al. (2005) Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin. J Exp Med 202:541-9