Inflammatory cytokines increase extracellular procathepsin D in permanent and primary endothelial cell cultures

European Journal of Cell Biology

Volumn 87, Issue 5, 2008, Pages 311-323

  Erdmann, Sabine ^a   Ricken, Albert ^a   Hummitzsch, Katja ^a   Merkwitz, Claudia ^a   Schliebe, Nicole ^a   Gaunitz, Frank ^a   Strotmann, Rainer ^a   Spanel Borowski, Katharina ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Cathepsin D; Ea.hy 926 cells; Endothelial cells; Extracellular proteolysis; HUVEC; Interferon ; Procathepsin D; Tumor necrosis factor

Indexed keywords

CASPASE 3; CATHEPSIN D; CYTOKINE; GAMMA INTERFERON; MESSENGER RNA; PROCATHEPSIN D; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL ISOLATION; CELL LINE; CELL LYSATE; CONTROLLED STUDY; CULTURE MEDIUM; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; STIMULATION; UMBILICAL VEIN; WESTERN BLOTTING;

APOPTOSIS; ASPARTIC ENDOPEPTIDASES; CATHEPSIN D; CELL LINE; CELLS, CULTURED; CULTURE MEDIA; ENDOTHELIAL CELLS; ENZYME PRECURSORS; EXTRACELLULAR SPACE; GENE EXPRESSION REGULATION; HUMANS; HYDROGEN-ION CONCENTRATION; INTERFERON TYPE II; TUMOR NECROSIS FACTOR-ALPHA;

EID: 42149170633     PISSN: 01719335     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejcb.2008.01.005     Document Type: Article

References (44)

1. Baechle D., Flad T., Cansier A., Steffen H., Schittek B., Tolson J., Herrmann T., Dihazi H., Beck A., Mueller C.A., and Kalbacher H. Cathepsin D is present in human eccrine sweat and involved in the postsecretory processing of the antimicrobial peptide DCD-1L. J. Biol. Chem. 281 (2006) 5406-5415
2. Beaujouin M., Baghdiguian S., Glondu-Lassis M., Berchem G., and Liaudet-Coopman E. Overexpression of both catalytically active and -inactive cathepsin D by cancer cells enhances apoptosis-dependent chemo-sensitivity. Oncogene 25 (2006) 1967-1973
3. Berchem G., Glondu M., Gleizes M., Brouillet J.P., Vignon F., Garcia M., and Liaudet-Coopman E. Cathepsin-D affects multiple tumor progression steps in vivo: proliferation, angiogenesis and apoptosis. Oncogene 21 (2002) 5951-5955
4. Bouis D., Hospers G.A., Meijer C., Molema G., and Mulder N.H. Endothelium in vitro: a review of human vascular endothelial cell lines for blood vessel-related research. Angiogenesis 4 (2001) 91-102
5. Briozzo P., Morisset M., Capony F., Rougeot C., and Rochefort H. In vitro degradation of extracellular matrix with Mr 52,000 cathepsin D secreted by breast cancer cells. Cancer Res. 48 (1988) 3688-3692
6. Briozzo P., Badet J., Capony F., Pieri I., Montcourrier P., Barritault D., and Rochefort H. MCF7 mammary cancer cells respond to bFGF and internalize it following its release from extracellular matrix: a permissive role of cathepsin D. Exp. Cell Res. 194 (1991) 252-259
7. Edgell C.J., McDonald C.C., and Graham J.B. Permanent cell line expressing human factor VIII-related antigen established by hybridization. Proc. Natl. Acad. Sci. USA 80 (1983) 3734-3737
8. Erdmann S., Ricken A.M., Merkwitz C., Struman I., Roberta C., Hummitzsch K., Gaunitz F., Isidoro C., Martial J., and Spanel-Borowski K. The expression of prolactin and its cathepsin D-mediated cleavage in the bovine corpus luteum vary with the oestrous cycle. Am. J. Physiol. Endocrinol. Metab. 293 (2007) E1365-E1377
9. Fenyves A.M., Behrens J., and Spanel-Borowski K. Cultured microvascular endothelial cells (MVEC) differ in cytoskeleton, expression of cadherins and fibronectin matrix. A study under the influence of interferon-gamma. J. Cell Sci. 106 (1993) 879-890
10. Gerritsen M.E., and Bloor C.M. Endothelial cell gene expression in response to injury. FASEB J. 7 (1993) 523-532
11. Gruemmer R., Klein-Hitpass L., and Neulen J. Regulation of gene expression in endothelial cells: the role of human follicular fluid. J. Mol. Endocrinol. 34 (2005) 37-46
12. Hausmann M., Obermeier F., Schreiter K., Spottl T., Falk W., Scholmerich J., Herfarth H., Saftig P., and Rogler G. Cathepsin D is up-regulated in inflammatory bowel disease macrophages. Clin. Exp. Immunol. 136 (2004) 157-167
13. Huynh H.K., and Dorovini-Zis K. Effects of interferon-gamma on primary cultures of human brain microvessel endothelial cells. Am. J. Pathol. 142 (1993) 1265-1278
14. Johansson A.C., Steen H., Ollinger K., and Roberg K. Cathepsin D mediates cytochrome c release and caspase activation in human fibroblast apoptosis induced by staurosporine. Cell Death Differ 10 (2003) 1253-1259
15. Lahav M., Meidan R., Amsterdam A., Gebauer H., and Lindner H.R. Intracellular distribution of cathepsin D in rat corpora lutea in relation to reproductive state and the action of prostaglandin F2alpha and prolactin. J. Endocrinol. 75 (1977) 317-324
16. Laurent-Matha V., Maruani-Herrmann S., Prebois C., Beaujouin M., Glondu M., Noel A., Alvarez-Gonzalez M.L., Blacher S., Coopman P., Baghdiguian S., Gilles C., Loncarek J., Freiss G., Vignon F., and Liaudet-Coopman E. Catalytically inactive human cathepsin D triggers fibroblast invasive growth. J. Cell Biol. 168 (2005) 489-499
17. Laurent-Matha V., Derocq D., Prebois C., Katunuma N., and Liaudet-Coopman E. Processing of human cathepsin D is independent of its catalytic function and auto-activation: involvement of cathepsins L and B. J. Biochem. (Tokyo) 139 (2006) 363-371
18. Lee H., Baek S., Joe S.J., and Pyo S.N. Modulation of IFN-gamma production by TNF-alpha in macrophages from the tumor environment: significance as an angiogenic switch. Int. Immunopharmacol. 6 (2006) 71-78
19. Leto G., Tumminello F.M., Crescimanno M., Flandina C., and Gebbia N. Cathepsin D expression levels in nongynecological solid tumors: clinical and therapeutic implications. Clin. Exp. Metastasis 21 (2004) 91-106
20. Li J.H., and Pober J.S. The cathepsin B death pathway contributes to TNF plus IFN-gamma-mediated human endothelial injury. J. Immunol. 175 (2005) 1858-1866
21. Livak K.J., and Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25 (2001) 402-408
22. Lkhider M., Castino R., Bouguyon E., Isidoro C., and Ollivier-Bousquet M. Cathepsin D released by lactating rat mammary epithelial cells is involved in prolactin cleavage under physiological conditions. J. Cell Sci. 117 (2004) 5155-5164
23. Mawatari M., Kohno K., Mizoguchi H., Matsuda T., Asoh K., Van Damme J., Welgus H.G., and Kuwano M. Effects of tumor necrosis factor and epidermal growth factor on cell morphology, cell surface receptors, and the production of tissue inhibitor of metalloproteinases and IL-6 in human microvascular endothelial cells. J. Immunol. 143 (1989) 1619-1627
24. Morikawa W., Yamamoto K., Ishikawa S., Takemoto S., Ono M., Fukushi J., Naito S., Nozaki C., Iwanaga S., and Kuwano M. Angiostatin generation by cathepsin D secreted by human prostate carcinoma cells. J. Biol. Chem. 275 (2000) 38912-38920
25. Nelimarkka L., Kainulainen V., Schonherr E., Moisander S., Jortikka M., Lammi M., Elenius K., Jalkanen M., and Jarvelainen H. Expression of small extracellular chondroitin/dermatan sulfate proteoglycans is differentially regulated in human endothelial cells. J. Biol. Chem. 272 (1997) 12730-12737
26. Pandita R., Pocsik E., and Aggarwal B.B. Interferon-gamma induces cell surface expression for both types of tumor necrosis factor receptors. FEBS Lett. 312 (1992) 87-90
27. Pate J.L., and Landis Keyes P. Immune cells in the corpus luteum: friends or foes?. Reproduction 122 (2001) 665-676
28. Piwnica D., Fernandez I., Binart N., Touraine P., Kelly P.A., and Goffin V. A new mechanism for prolactin processing into 16 K PRL by secreted cathepsin D. Mol. Endocrinol. 20 (2006) 3263-3278
29. Roberg K., Kagedal K., and Ollinger K. Microinjection of cathepsin D induces caspase-dependent apoptosis in fibroblasts. Am. J. Pathol. 161 (2002) 89-96
30. Rochefort H., Cavailles V., Augereau P., Capony F., Maudelonde T., Touitou I., and Garcia M. Overexpression and hormonal regulation of pro-cathepsin D in mammary and endometrial cancer. J. Steroid Biochem. 34 (1989) 177-182
31. Rochefort H., Garcia M., Glondu M., Laurent V., Liaudet E., Rey J.M., and Roger P. Cathepsin D in breast cancer: mechanisms and clinical applications, a 1999 overview. Clin. Chim. Acta 291 (2000) 157-170
32. 2+-regulated exocytic vesicles in fibroblasts and epithelial cells. J. Cell Biol. 137 (1997) 93-104
33. Saftig P., Hetman M., Schmahl W., Weber K., Heine L., Mossmann H., Koster A., Hess B., Evers M., von Figura K., and Peters C. Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells. EMBO J. 14 (1995) 3599-3608
34. Schestkowa O., Geisel D., Jacob R., and Hasilik A. The catalytically inactive precursor of cathepsin D induces apoptosis in human fibroblasts and HeLa cells. J. Cell. Biochem. 101 (2007) 1558-1566
35. Spanel-Borowski K., Ricken A.M., and Patton W.F. Cytokeratin-positive and cytokeratin-negative cultured endothelial cells from bovine aorta and vena cava. Differentiation 57 (1994) 225-234
36. Vashishta A., Saraswat Ohri S., Vetvickova J., Fusek M., Ulrichova J., and Vetvicka V. Procathepsin D secreted by HaCaT keratinocyte cells--a novel regulator of keratinocyte growth. Eur. J. Cell Biol. 86 (2007) 303-313
37. Vetvicka V., Vetvickova J., Hilgert I., Voburka Z., and Fusek M. Analysis of the interaction of procathepsin D activation peptide with breast cancer cells. Int. J. Cancer 73 (1997) 403-409
38. Vetvicka V., Benes P., and Fusek M. Procathepsin D in breast cancer: what do we know? Effects of ribozymes and other inhibitors. Cancer Gene Ther 9 (2002) 854-863
39. Weiser S., Miu J., Ball H.J., and Hunt N.H. Interferon-gamma synergises with tumour necrosis factor and lymphotoxin-alpha to enhance the mRNA and protein expression of adhesion molecules in mouse brain endothelial cells. Cytokine 37 (2007) 84-91
40. Westley B., and Rochefort H. A secreted glycoprotein induced by estrogen in human breast cancer cell lines. Cell 20 (1980) 353-362
41. Winkler C., Denker K., Wortelkamp S., and Sickmann A. Silver- and Coomassie-staining protocols: detection limits and compatibility with ESI MS. Electrophoresis 28 (2007) 2095-2099
42. Xie S., and Kang J.X. Differential expression of the mannose 6-phosphate/insulin-like growth factor-II receptor in human breast cancer cell lines of different invasive potential. Med. Sci. Monit. 8 (2002) BR293-BR300
43. Yasuda Y., Kageyama T., Akamine A., Shibata M., Kominami E., Uchiyama Y., and Yamamoto K. Characterization of new fluorogenic substrates for the rapid and sensitive assay of cathepsin E and cathepsin D. J. Biochem. (Tokyo) 125 (1999) 1137-1143
44. Yoshimura A. Signal transduction of inflammatory cytokines and tumor development. Cancer Sci. 97 (2006) 439-447