메뉴 건너뛰기




Volumn 48, Issue 2, 2008, Pages

Potential roles for pharmacists in pharmacogenetics

Author keywords

Pharmacists; Pharmacogenetics; Research

Indexed keywords

EDUCATION; HUMAN; MEDICAL RESEARCH; METHODOLOGY; ORGANIZATION AND MANAGEMENT; PHARMACIST; PHARMACOGENETICS; PROFESSIONAL STANDARD; REVIEW;

EID: 42149168055     PISSN: 15443191     EISSN: 15443450     Source Type: Journal    
DOI: 10.1331/JAPhA.2008.07050     Document Type: Article
Times cited : (33)

References (52)
  • 1
    • 4344580348 scopus 로고    scopus 로고
    • Pharmacogenomics and pharmacogenetics: Future role of molecular diagnostics in the clinical diagnostic laboratory
    • Ito RK, Demers LM. Pharmacogenomics and pharmacogenetics: future role of molecular diagnostics in the clinical diagnostic laboratory. Clin Chem. 2004;50:1526-7.
    • (2004) Clin Chem , vol.50 , pp. 1526-1527
    • Ito, R.K.1    Demers, L.M.2
  • 2
  • 5
    • 0033632208 scopus 로고    scopus 로고
    • Human Genome Project and pharmacogenomics: Implications for pharmacy
    • Carrico JM. Human Genome Project and pharmacogenomics: implications for pharmacy. J Am Pharm Assoc. 2000;40:115-6.
    • (2000) J Am Pharm Assoc , vol.40 , pp. 115-116
    • Carrico, J.M.1
  • 6
    • 0038744249 scopus 로고    scopus 로고
    • How genetics could change pharmacy
    • How genetics could change pharmacy. The Pharmaceutical Journal. 2003;270:508-9.
    • (2003) The Pharmaceutical Journal , vol.270 , pp. 508-509
  • 8
    • 0036124608 scopus 로고    scopus 로고
    • Pharmaceutical education in the wake of genomic technologies for drug development and personalized medicine
    • Vizirianakis IS. Pharmaceutical education in the wake of genomic technologies for drug development and personalized medicine. Eur J Pharm Sci. 2002;15:243-50.
    • (2002) Eur J Pharm Sci , vol.15 , pp. 243-250
    • Vizirianakis, I.S.1
  • 9
    • 3543052218 scopus 로고    scopus 로고
    • From pharmacogenetics to personalized medicine: A vital need for educating health professionals and the community
    • Frueh FW, Gurwitz D. From pharmacogenetics to personalized medicine: a vital need for educating health professionals and the community. Pharmacogenomics. 2004;5:571-9.
    • (2004) Pharmacogenomics , vol.5 , pp. 571-579
    • Frueh, F.W.1    Gurwitz, D.2
  • 10
    • 33646007664 scopus 로고    scopus 로고
    • Teaching and practicing pharmacogenomics: A complex matter
    • Lunshof J. Teaching and practicing pharmacogenomics: a complex matter. Pharmacogenomics. 2006;7:243-6.
    • (2006) Pharmacogenomics , vol.7 , pp. 243-246
    • Lunshof, J.1
  • 11
    • 23644449909 scopus 로고    scopus 로고
    • Pharmacogenomics education: International Society of Pharmacogenomics recommendations for medical, pharmaceutical, and health schools deans of education
    • Gurwitz D, Lunshof JE, Dedoussis G, et al. Pharmacogenomics education: International Society of Pharmacogenomics recommendations for medical, pharmaceutical, and health schools deans of education. Pharmacogenomics J. 2005;5:221-5.
    • (2005) Pharmacogenomics J , vol.5 , pp. 221-225
    • Gurwitz, D.1    Lunshof, J.E.2    Dedoussis, G.3
  • 12
    • 0037450581 scopus 로고    scopus 로고
    • The secret of life
    • Gibbs N. The secret of life. TIME Magazine. 2003;161(7):42-5.
    • (2003) TIME Magazine , vol.161 , Issue.7 , pp. 42-45
    • Gibbs, N.1
  • 13
    • 0038670579 scopus 로고    scopus 로고
    • The human phenome project
    • Freimer N, Sabatti C. The human phenome project. Nat Genet. 2003;34:15-21.
    • (2003) Nat Genet , vol.34 , pp. 15-21
    • Freimer, N.1    Sabatti, C.2
  • 15
    • 22844448777 scopus 로고    scopus 로고
    • Priorities and standards in pharmacogenetic research
    • Need AC, Motulsky AG, Goldstein DB. Priorities and standards in pharmacogenetic research. Nat Genet. 2005;37:671-81.
    • (2005) Nat Genet , vol.37 , pp. 671-681
    • Need, A.C.1    Motulsky, A.G.2    Goldstein, D.B.3
  • 16
    • 4544335467 scopus 로고    scopus 로고
    • Translation of pharmacogenomics and pharmacogenetics: A regulatory perspective
    • Lesko LJ, Woodcock J. Translation of pharmacogenomics and pharmacogenetics: a regulatory perspective. Nat Rev Drug Discov. 2004;3:763-9.
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 763-769
    • Lesko, L.J.1    Woodcock, J.2
  • 17
    • 0032563666 scopus 로고    scopus 로고
    • Comparison of an anticoagulation clinic with usual medical care: Anticoagulation control, patient outcomes, and health care costs
    • Chiquette E, Amato MG, Bussey HI. Comparison of an anticoagulation clinic with usual medical care: anticoagulation control, patient outcomes, and health care costs. Arch Intern Med. 1998;158:1641-7.
    • (1998) Arch Intern Med , vol.158 , pp. 1641-1647
    • Chiquette, E.1    Amato, M.G.2    Bussey, H.I.3
  • 18
    • 33745256203 scopus 로고    scopus 로고
    • Pharmacy-managed anticoagulation: Assessment of in-hospital efficacy and evaluation of financial impact and community acceptance
    • Donovan JL, Drake JA, Whittaker P, Tran MT. Pharmacy-managed anticoagulation: assessment of in-hospital efficacy and evaluation of financial impact and community acceptance. J Thromb Thrombolysis. 2006;22:23-30.
    • (2006) J Thromb Thrombolysis , vol.22 , pp. 23-30
    • Donovan, J.L.1    Drake, J.A.2    Whittaker, P.3    Tran, M.T.4
  • 19
    • 0348038821 scopus 로고    scopus 로고
    • Comparison of physician- and pharmacist-managed warfarin sodium treatment in open heart surgery patients
    • Tschol N, Lai DK, Tilley JA, et al. Comparison of physician- and pharmacist-managed warfarin sodium treatment in open heart surgery patients. Can J Cardiol. 2003;19:1413-7.
    • (2003) Can J Cardiol , vol.19 , pp. 1413-1417
    • Tschol, N.1    Lai, D.K.2    Tilley, J.A.3
  • 20
    • 33749493824 scopus 로고    scopus 로고
    • Clinical and economic outcomes of pharmacist- managed antiepileptic drug therapy
    • Bond CA, Raehl CL. Clinical and economic outcomes of pharmacist- managed antiepileptic drug therapy. Pharmacotherapy. 2006;26:1369-78.
    • (2006) Pharmacotherapy , vol.26 , pp. 1369-1378
    • Bond, C.A.1    Raehl, C.L.2
  • 21
    • 0642368627 scopus 로고    scopus 로고
    • Assessment of clinical pharmacist management of lipid-lowering therapy in a primary care setting
    • Till LT, Voris JC, Horst JB. Assessment of clinical pharmacist management of lipid-lowering therapy in a primary care setting. J Manag Care Pharm. 2003;9:269-73.
    • (2003) J Manag Care Pharm , vol.9 , pp. 269-273
    • Till, L.T.1    Voris, J.C.2    Horst, J.B.3
  • 22
    • 0033674433 scopus 로고    scopus 로고
    • Clinical and economic impact of ambulatory care clinical pharmacists in management of dyslipidemia in older adults: The IMPROVE study: Impact of Managed Pharmaceutical Care on Resource Utilization and Outcomes in Veterans Affairs Medical Centers
    • Ellis SL, Carter BL, Malone DC, et al. Clinical and economic impact of ambulatory care clinical pharmacists in management of dyslipidemia in older adults: the IMPROVE study: Impact of Managed Pharmaceutical Care on Resource Utilization and Outcomes in Veterans Affairs Medical Centers. Pharmacotherapy. 2000;20:1508-16.
    • (2000) Pharmacotherapy , vol.20 , pp. 1508-1516
    • Ellis, S.L.1    Carter, B.L.2    Malone, D.C.3
  • 23
    • 33845450660 scopus 로고    scopus 로고
    • Effect of a pharmacy care program on medication adherence and persistence, blood pressure, and low-density lipoprotein cholesterol: A randomized controlled trial
    • Lee JK, Grace KA, Taylor AJ. Effect of a pharmacy care program on medication adherence and persistence, blood pressure, and low-density lipoprotein cholesterol: a randomized controlled trial. JAMA. 2006;296:2563-71.
    • (2006) JAMA , vol.296 , pp. 2563-2571
    • Lee, J.K.1    Grace, K.A.2    Taylor, A.J.3
  • 24
    • 0028840258 scopus 로고
    • Hemorrhagic complications of anticoagulant treatment
    • Levine MN, Raskob G, Landefeld S, Hirsh J. Hemorrhagic complications of anticoagulant treatment. Chest. 1995;108(4 suppl):276S-290S.
    • (1995) Chest , vol.108 , Issue.4 SUPPL.
    • Levine, M.N.1    Raskob, G.2    Landefeld, S.3    Hirsh, J.4
  • 25
    • 0027257511 scopus 로고
    • Anticoagulant-related bleeding: Clinical epidemiology, prediction, and prevention
    • Landefeld CS, Beyth RJ. Anticoagulant-related bleeding: clinical epidemiology, prediction, and prevention. Am J Med. 1993;95:315-28.
    • (1993) Am J Med , vol.95 , pp. 315-328
    • Landefeld, C.S.1    Beyth, R.J.2
  • 26
    • 0141832724 scopus 로고    scopus 로고
    • Pharmacogenetics of CYP2C9 and interindividual variability in anticoagulant response to warfarin
    • Takahashi H, Echizen H. Pharmacogenetics of CYP2C9 and interindividual variability in anticoagulant response to warfarin. Pharmacogenomics J. 2003;3:202-14.
    • (2003) Pharmacogenomics J , vol.3 , pp. 202-214
    • Takahashi, H.1    Echizen, H.2
  • 27
    • 0036194038 scopus 로고    scopus 로고
    • The frequency and effects of cytochrome P450 (CYP) 2C9 polymorphisms in patients receiving warfarin
    • Tabrizi AR, Zehnbauer BA, Borecki IB, et al. The frequency and effects of cytochrome P450 (CYP) 2C9 polymorphisms in patients receiving warfarin. J Am Coll Surg. 2002;194:267-73.
    • (2002) J Am Coll Surg , vol.194 , pp. 267-273
    • Tabrizi, A.R.1    Zehnbauer, B.A.2    Borecki, I.B.3
  • 28
    • 0029564238 scopus 로고
    • Genetic polymorphism of CYP2C9 and its effect on warfarin maintenance dose requirement in patients undergoing anticoagulation therapy
    • Furuya H, Fernandez-Salguero P, Gregory W, et al. Genetic polymorphism of CYP2C9 and its effect on warfarin maintenance dose requirement in patients undergoing anticoagulation therapy. Pharmacogenetics. 1995;5:389-92.
    • (1995) Pharmacogenetics , vol.5 , pp. 389-392
    • Furuya, H.1    Fernandez-Salguero, P.2    Gregory, W.3
  • 29
    • 0037012465 scopus 로고    scopus 로고
    • Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy
    • Higashi MK, Veenstra DL, Kondo LM, et al. Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy. JAMA. 2002;287:1690-8.
    • (2002) JAMA , vol.287 , pp. 1690-1698
    • Higashi, M.K.1    Veenstra, D.L.2    Kondo, L.M.3
  • 31
    • 11244332058 scopus 로고    scopus 로고
    • A polymorphism in the VKORC1 gene is associated with an interindividual variability in the dose-anticoagulant effect of warfarin
    • D'Andrea G, D'Ambrosio RL, Di Perna P, et al. A polymorphism in the VKORC1 gene is associated with an interindividual variability in the dose-anticoagulant effect of warfarin. Blood. 2005;105:645-9.
    • (2005) Blood , vol.105 , pp. 645-649
    • D'Andrea, G.1    D'Ambrosio, R.L.2    Di Perna, P.3
  • 32
    • 85006526547 scopus 로고    scopus 로고
    • Evaluating the potential impact of pharmacogenomics on ADRs
    • Oren E, McCart G, Phillips KA. Evaluating the potential impact of pharmacogenomics on ADRs. J Manag Care Pharm. 2002;8:285-90.
    • (2002) J Manag Care Pharm , vol.8 , pp. 285-290
    • Oren, E.1    McCart, G.2    Phillips, K.A.3
  • 33
    • 0021923341 scopus 로고
    • Retrospective evaluation of a pharmacist-managed warfarin anticoagulation clinic
    • Garabedian-Ruffalo SM, Gray DR, Sax MJ, Ruffalo RL. Retrospective evaluation of a pharmacist-managed warfarin anticoagulation clinic. Am J Hosp Pharm. 1985;42:304-8.
    • (1985) Am J Hosp Pharm , vol.42 , pp. 304-308
    • Garabedian-Ruffalo, S.M.1    Gray, D.R.2    Sax, M.J.3    Ruffalo, R.L.4
  • 34
    • 0034018727 scopus 로고    scopus 로고
    • Optimization of inpatient warfarin therapy: Impact of daily consultation by a pharmacist- managed anticoagulation service
    • Dager WE, Branch JM, King JH, et al. Optimization of inpatient warfarin therapy: impact of daily consultation by a pharmacist- managed anticoagulation service. Ann Pharmacother. 2000;3:567-72.
    • (2000) Ann Pharmacother , vol.3 , pp. 567-572
    • Dager, W.E.1    Branch, J.M.2    King, J.H.3
  • 35
    • 23044440450 scopus 로고    scopus 로고
    • The impact of CYP2C9 and VKORC1 genetic polymorphism and patient characteristics upon warfarin dose requirements: Proposal for a new dosing regimen
    • Sconce EA, Khan TI, Wynne HA, et al. The impact of CYP2C9 and VKORC1 genetic polymorphism and patient characteristics upon warfarin dose requirements: proposal for a new dosing regimen. Blood. 2005;106:2329-33.
    • (2005) Blood , vol.106 , pp. 2329-2333
    • Sconce, E.A.1    Khan, T.I.2    Wynne, H.A.3
  • 36
    • 33646371252 scopus 로고    scopus 로고
    • Regulatory perspectives on pharmacogenomics: A review of the literature on key issues faced by the United States Food and Drug Administration
    • Phillips KA, Van Bebber SL. Regulatory perspectives on pharmacogenomics: a review of the literature on key issues faced by the United States Food and Drug Administration. Med Care Res Rev. 2006;63:301-26.
    • (2006) Med Care Res Rev , vol.63 , pp. 301-326
    • Phillips, K.A.1    Van Bebber, S.L.2
  • 37
    • 33845999625 scopus 로고    scopus 로고
    • Genetic testing in cancer therapeutics
    • Ezzeldin HH, Diasio RB. Genetic testing in cancer therapeutics. Clin Cancer Res. 2006;12:4137-41.
    • (2006) Clin Cancer Res , vol.12 , pp. 4137-4141
    • Ezzeldin, H.H.1    Diasio, R.B.2
  • 38
    • 13844316592 scopus 로고    scopus 로고
    • Cancer pharmacogenomics: Powerful tools in cancer chemotherapy and drug development
    • Lee W, Lockhart AC, Kim RB, Rothenberg ML. Cancer pharmacogenomics: powerful tools in cancer chemotherapy and drug development. Oncologist. 2005;10:104-11.
    • (2005) Oncologist , vol.10 , pp. 104-111
    • Lee, W.1    Lockhart, A.C.2    Kim, R.B.3    Rothenberg, M.L.4
  • 40
    • 33644525291 scopus 로고    scopus 로고
    • Uridine diphosphate glucuronosyl transferase 1A1 promoter polymorphism predicts the risk of gastrointestinal toxicity and fatigue induced by irinotecan-based chemotherapy
    • Massacesi C, Terrazzino S, Marcucci F, et al. Uridine diphosphate glucuronosyl transferase 1A1 promoter polymorphism predicts the risk of gastrointestinal toxicity and fatigue induced by irinotecan-based chemotherapy. Cancer. 2006;106:1007-16.
    • (2006) Cancer , vol.106 , pp. 1007-1016
    • Massacesi, C.1    Terrazzino, S.2    Marcucci, F.3
  • 41
    • 2342459714 scopus 로고    scopus 로고
    • Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan
    • Innocenti F, Undevia SD, Iyer L, et al. Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan. J Clin Oncol. 2004;22:1382-8.
    • (2004) J Clin Oncol , vol.22 , pp. 1382-1388
    • Innocenti, F.1    Undevia, S.D.2    Iyer, L.3
  • 42
    • 0036025450 scopus 로고    scopus 로고
    • UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity
    • Iyer L, Das S, Janisch L, et al. UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity. Pharmacogenomics J. 2002;2:43-7.
    • (2002) Pharmacogenomics J , vol.2 , pp. 43-47
    • Iyer, L.1    Das, S.2    Janisch, L.3
  • 43
    • 0025837127 scopus 로고
    • Altered mercaptopurine metabolism, toxic effects, and dosage requirement in a thiopurine methyltransferase-deficient child with acute lymphocytic leukemia
    • Evans WE, Horner M, Chu YQ, et al. Altered mercaptopurine metabolism, toxic effects, and dosage requirement in a thiopurine methyltransferase- deficient child with acute lymphocytic leukemia. J Pediatr. 1991;119:985-9.
    • (1991) J Pediatr , vol.119 , pp. 985-989
    • Evans, W.E.1    Horner, M.2    Chu, Y.Q.3
  • 44
    • 0035871560 scopus 로고    scopus 로고
    • Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine
    • Evans WE, Hon YY, Bomgaars L, et al. Preponderance of thiopurine S-methyltransferase deficiency and heterozygosity among patients intolerant to mercaptopurine or azathioprine. J Clin Oncol. 2001;19:2293-301.
    • (2001) J Clin Oncol , vol.19 , pp. 2293-2301
    • Evans, W.E.1    Hon, Y.Y.2    Bomgaars, L.3
  • 45
    • 20144365645 scopus 로고    scopus 로고
    • Thiopurine methyltransferase (TPMT) genotype and early treatment response to mercaptopurine in childhood acute lymphoblastic leukemia
    • Stanulla M, Schaeffeler E, Flohr T, et al. Thiopurine methyltransferase (TPMT) genotype and early treatment response to mercaptopurine in childhood acute lymphoblastic leukemia. JAMA. 2005;293:1485-9.
    • (2005) JAMA , vol.293 , pp. 1485-1489
    • Stanulla, M.1    Schaeffeler, E.2    Flohr, T.3
  • 46
    • 84873514613 scopus 로고    scopus 로고
    • Greenville, N.C.: DSM Pharmaceuticals
    • Purinethol [package insert]. Greenville, N.C.: DSM Pharmaceuticals: 2003.
    • (2003) Purinethol [Package Insert]
  • 47
    • 18744381845 scopus 로고    scopus 로고
    • Pharmacogenetic testing for drug metabolizing enzymes: Is it happening in practice?
    • Gardiner SJ, Begg EJ. Pharmacogenetic testing for drug metabolizing enzymes: is it happening in practice? Pharmacogenet Genomics. 2005;15:365-9.
    • (2005) Pharmacogenet Genomics , vol.15 , pp. 365-369
    • Gardiner, S.J.1    Begg, E.J.2
  • 48
    • 33845863919 scopus 로고    scopus 로고
    • Novel personalized medicine technology: UGT1A1 testing for irinotecan as a case study
    • Van Bebber SL, Keegan HL, Phillips KA, Issa AM. Novel personalized medicine technology: UGT1A1 testing for irinotecan as a case study. Future Medicine. 2006;3:415-9.
    • (2006) Future Medicine , vol.3 , pp. 415-419
    • Van Bebber, S.L.1    Keegan, H.L.2    Phillips, K.A.3    Issa, A.M.4
  • 50
    • 84891874890 scopus 로고    scopus 로고
    • Accessed at December 7, 2006
    • DHPLC determination of TPMT polymorphisms. Accessed at www.clinicaltrials.gov/ct/show/NCT00402090?order=1, December 7, 2006.
    • DHPLC Determination of TPMT Polymorphisms
  • 51
    • 33747168764 scopus 로고    scopus 로고
    • Cost-effectiveness of pharmacogenomics in clinical practice: A case study of thiopurine methyltransferase genotyping in acute lymphoblastic leukemia in Europe
    • van den Akker-van Marle ME, Gurwitz D, Detmar SB, et al. Cost-effectiveness of pharmacogenomics in clinical practice: a case study of thiopurine methyltransferase genotyping in acute lymphoblastic leukemia in Europe. Pharmacogenomics. 2006;7:783-92.
    • (2006) Pharmacogenomics , vol.7 , pp. 783-792
    • Van Den Akker-Van Marle, M.E.1    Gurwitz, D.2    Detmar, S.B.3
  • 52
    • 33749064790 scopus 로고    scopus 로고
    • Researchers draft guidelines for clinical use of pharmacogenomics
    • Hampton T. Researchers draft guidelines for clinical use of pharmacogenomics. JAMA. 2006;296:1453-4.
    • (2006) JAMA , vol.296 , pp. 1453-1454
    • Hampton, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.