Secondary effects of catalytic diesel particulate filters: Reduced aryl hydrocarbon receptor-mediated activity of the exhaust

Environmental Science and Technology

Volumn 42, Issue 8, 2008, Pages 2992-2998

  Wenger, Daniela ^a,c   Gerecke, Andreas C ^a   Heeb, Norbert V ^a   Zennegg, Markus ^a   Kohler, Martin ^a   Naegeli, Hanspeter ^b   Zenobi, Renato ^c  

^a SWISS FEDERAL LABORATORIES FOR MATERIALS SCIENCE AND TECHNOLOGY   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ARYL HYDROCARBON RECEPTOR (AHR); TOXIC SUBSTANCES;

CATALYST ACTIVITY; COPPER; FILTERS (FOR FLUIDS); HYDROCARBONS;

DIESEL FUELS;

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; AROMATIC HYDROCARBON RECEPTOR AGONIST; COPPER; DIESEL FUEL; FURAN DERIVATIVE; IRON; POLYCHLORINATED DIBENZODIOXIN; POLYCYCLIC AROMATIC HYDROCARBON; UNCLASSIFIED DRUG;

CATALYST ACTIVITY; COPPER; DIESEL FUELS; FILTERS (FOR FLUIDS); HYDROCARBONS;

BIOTRANSFORMATION; CATALYSIS; CONCENTRATION (COMPOSITION); CYTOLOGY; DETOXIFICATION; DIESEL ENGINE; FILTER; HYDROCARBON; PAH; TOXIC SUBSTANCE;

AIR ANALYSIS; AIR SAMPLING; ARTICLE; BIOTRANSFORMATION; CATALYSIS; DIESEL PARTICULATE FILTER; EXHAUST GAS; FILTER; GAS CHROMATOGRAPHY; PARTICULATE MATTER; QUANTITATIVE ANALYSIS; REPORTER GENE; TECHNOLOGY;

AIR POLLUTANTS; AIR POLLUTION; ANIMALS; BENZOFURANS; CATALYSIS; CELL LINE, TUMOR; COPPER; CYCLOHEXANES; FILTRATION; GASOLINE; GENES, REPORTER; IRON; LUCIFERASES; POLYCYCLIC HYDROCARBONS, AROMATIC; RATS; RECEPTORS, ARYL HYDROCARBON; TETRACHLORODIBENZODIOXIN; VEHICLE EMISSIONS;

EID: 42149141731     PISSN: 0013936X     EISSN: None     Source Type: Journal    
DOI: 10.1021/es071827x     Document Type: Article

References (27)

1. Kittelson, D. B. Engines and nanoparticles: A review. J. Aerosol Sci. 1998, 29, 575-588.
2. Schauer, J. J.; Kleeman, M. J.; Cass, G. R.; Simoneit, B. R. T. Measurement of emissions from air pollution sources. 2. C1 through C30 organic compounds from medium duty diesel trucks. Environ. Sci. Technol. 1999, 33, 1578-1587.
3. Westerholm, R.; Christensen, A.; Tornqvist, M.; Ehrenberg, L.; Rannug, U.; Sjogren, M.; Rafter, J.; Soontjens, C.; Almen, J.; Gragg, K. Comparison of exhaust emissions from Swedish environmental classified diesel fuel (MK1) and European Program on Emissions, Fuels and Engine Technologies (EPEFE) reference fuel: A chemical and biological characterization with viewpoints on cancer risk. Environ. Sci. Technol. 2001, 35, 1748-1754.
4. Denison, M. S.; Whitlock, J. P. Xenobiotic-inducible transcription of cytochrome-P450 genes. J. Biol. Chem. 1995, 270, 18175-18178.
5. Gelboin, H. V. Benzo[a]pyrene metabolism, activation, and carcinogenesis - role and regulation of mixed-function oxidases and related enzymes. Physiol. Rev. 1980, 60, 1107-1166.
6. Schmidt, J. V.; Bradfield, C. A. Ah receptor signaling pathways. Annu. Rev. Cell Dev. Biol. 1996, 12, 55-89.
7. Poland, A.; Knutson, J. C. 2,3,7,8-Tetrachlorodibenzo-paradioxin and related halogenated aromatic-hydrocarbons - examination of the mechanism of toxicity. Annu. Rev. Pharmacol. Toxicol. 1982, 22, 517-554.
8. Safe, S.; Wang, F.; Porter, W.; Duan, R.; McDougal, A. Ah receptor agonists as endocrine disruptors: antiestrogenic activity and mechanisms. Toxicol. Lett. 1998, 103, 343-347.
9. Kizu, R.; Okamura, K.; Toriba, A.; Mizokami, A.; Burnstein, K. L.; Klinge, C. M.; Hayakawa, K. Antiandrogenic activities of diesel exhaust particle extracts in PC3/AR human prostate carcinoma cells. Toxicol. Sci. 2003, 76, 299-309.
10. Watanabe, N.; Kurita, M. The masculinization of the fetus during pregnancy due to inhalation of diesel exhaust. Environ. Health Perspect. 2001, 109, 111-119.
11. Yoshida, S.; Sagai, M.; Oshio, S.; Umeda, T.; Ihara, T.; Sugamata, M.; Sugawara, I.; Takeda, K. Exposure to diesel exhaust affects the male reproductive system of mice. Int. J. Androl. 1999, 22, 307-315.
12. Mason, G. G. F. Dioxin-receptor ligands in urban air and vehicle exhaust. Environ. Health Perspect. 1994, 102, 111-116.
13. Meek, M. D. Ah receptor and estrogen receptor-dependent modulation of gene expression by extracts of diesel exhaust particles. Environ. Res. 1998, 79, 114-121.
14. Okamura, K.; Kizu, R.; Toriba, A.; Klinge, C. M.; Hayakawa, K. Antiestrogenic activity of extracts of diesel exhaust particulate matter in MCF-7 human breast carcinoma cells. Polycyclic Aromat. Compd. 2002, 22, 747-759.
15. Aarts, J.; Denison, M. S.; Cox, M. A.; Schalk, M. A. C.; Garrison, P. M.; Tullis, K.; Dehaan, L. H. J.; Brouwer, A. Species-specific antagonism of Ah receptor action by 2,2′,5,5′tetrachlorobiphenyl and 2,2′,3,3′,4,4′-hexachlorobiphenyl. Eur. J. Pharmacol., Environ. Toxicol. Pharmacol. Sect. 1995, 293, 463-474.
16. Behnisch, P. A.; Hosoe, K.; Sakai, S. Brominated dioxin-like compounds: In vitro assessment in comparison to classical dioxin-like compounds and other polyaromatic compounds. Environ. Int. 2003, 29, 861-877.
17. Machala, M.; Vondráček, J.; Bláha, L.; Ciganek, M.; Neča, J. Aryl hydrocarbon receptor-mediated activity of mutagenic polycyclic aromatic hydrocarbons determined using in vitro reporter gene assay. Mutat. Res. 2001, 497, 49-62.
18. Zhu, Y.; Hinds, W. C.; Kim, S.; Shen, S.; Sioutas, C. Study of ultrafine particles near a major highway with heavy-duty diesel traffic. Atmos. Environ. 2002, 36, 4323-4335.
19. Heeb, N. V.; Zennegg, M.; Gujer, E.; Honegger, P.; Zeyer, K.; Gfeller, U.; Wichser, A.; Kohler, M.; Schmid, P.; Emmenegger, L.; Ulrich, A.; Wenger, D.; Petermann, J.-L.; Czerwinksi, J.; Mosimann, T.; Kasper, M.; Mayer, A. Secondary effects of catalytic diesel particulate filters: copper-induced formation of PCDD/Fs. Environ. Sci. Technol. 2007, 41, 5789-5794.
20. Riedl, M.; Diaz-Sanchez, D. Biology of diesel exhaust effects on respiratory function. J. Allergy Clin. Immunol. 2005, 115, 221-228.
21. Delfino, R. J.; Sioutas, C.; Malik, S. Potential role of ultrafine particles in associations between airborne particle mass and cardiovascular health. Environ. Health Perspect. 2005, 113, 934-946.
22. Brüske-Hohlfeld, I.; Möhner, M.; Ahrens, W.; Pohlabeln, H.; Heinrich, J.; Kreuzer, M.; Jöckel, K.-H.; Wichmann, H.-E. Lung cancer risk in male workers occupationally exposed to diesel motor emissions in Germany. Am. J. Ind. Med. 1999, 36, 405-414.
23. van Setten, B. A. A. L.; Makkee, M.; Moulijn, J. A. Science and technology of catalytic diesel particulate filters. Catal. Rev. 2001, 43, 489-564.
24. European Committee for Standardization. Stationary Source Emissions-Determination of the Mass Concentration of PCDDs/PCDFs and Dioxin-Like PCBs-Part 1, Sampling of PCDDs/PCDFs. European Standard EN 1948-1: Brussels, 1996.
25. Wenger, D.; Gerecke, A. C.; Heeb, N. V.; Zenobi, R. Estrogenic and dioxin-like activity in diesel exhaust. Organohalogen Comp. 2006, 68, 1295-1298.
26. Li, H.; Banner, C. D.; Mason, G. G.; Westerholm, R. N.; Rafter, J.J. Determination of polycyclic aromatic compounds and dioxin receptor ligands present in diesel exhaust particulate extracts. Atmos. Environ. 1996, 30, 3537-3543.
27. Hamers, T.; van Schaardenburg, M. D.; Felzel, E. C.; Murk, A. J.; Koeman, J. H. The application of reporter gene assays for the determination of the toxic potency of diffuse air pollution. Sci. Total Environ. 2000, 262, 159-174.