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Volumn 32, Issue 1, 2008, Pages 8-11

Chemotherapy in the elderly

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE DERIVATIVE; ANTINEOPLASTIC AGENT; AROMATASE INHIBITOR; CAPECITABINE; CARBOPLATIN; CISPLATIN; CYCLOPHOSPHAMIDE; DOXORUBICIN; EPIPODOPHYLLOTOXIN DERIVATIVE; ETOPOSIDE; FLUOROURACIL; IFOSFAMIDE; KETOCONAZOLE; MACROLIDE; OXALIPLATIN; PHENYTOIN; SEROTONIN UPTAKE INHIBITOR; STEROID; TAXANE DERIVATIVE; VINCA ALKALOID;

EID: 42149106775     PISSN: 0311306X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (5)

References (50)
  • 1
    • 0030886129 scopus 로고    scopus 로고
    • Cancer burden in the aged: An epidemiologic and demographic overview
    • Yancik R. Cancer burden in the aged: an epidemiologic and demographic overview. Cancer. 1997;80:1273-1283.
    • (1997) Cancer , vol.80 , pp. 1273-1283
    • Yancik, R.1
  • 2
    • 0033950047 scopus 로고    scopus 로고
    • Aging and cancer in America: Demographic and epidemiologic perspectives
    • Yancik R, Ries LA. Aging and cancer in America: demographic and epidemiologic perspectives. Hematol Oncol Clin North Am. 2000;14:17-23.
    • (2000) Hematol Oncol Clin North Am , vol.14 , pp. 17-23
    • Yancik, R.1    Ries, L.A.2
  • 3
    • 42149101879 scopus 로고    scopus 로고
    • Australian Bureau of Statistics. Media release 4108.1, Older People, New South Wales, 2004; [Monograph on the internet, Released 17/09/2004. Available from:, nsf/mediareleasesbytitle/ 425918E7B04E56CECA256F11007A8731?OpenDocument
    • Australian Bureau of Statistics. Media release 4108.1 - Older People, New South Wales, 2004; [Monograph on the internet]. Released 17/09/2004. Available from: http://www.abs.gov.au/ausstats/abs@.nsf/mediareleasesbytitle/ 425918E7B04E56CECA256F11007A8731?OpenDocument
  • 4
    • 42149148537 scopus 로고    scopus 로고
    • Australian Bureau of Statistics. Media release 4430.0, Disability, Ageing and Carers, Australia: Summary of Findings, 2003, Monograph on the internet, Released 15/09/2004. Available from:, nsf/Latestproducts/4430.0Media%20Release12003?opendocument&tabname= Summary&prodno=4430.0&issue=2003&num=&view
    • Australian Bureau of Statistics. Media release 4430.0 - Disability, Ageing and Carers, Australia: Summary of Findings, 2003. [Monograph on the internet]. Released 15/09/2004. Available from: http://www.abs.gov.au/AUSSTATS/ abs@.nsf/Latestproducts/4430.0Media%20Release12003?opendocument&tabname= Summary&prodno=4430.0&issue=2003&num=&view
  • 5
    • 0033619959 scopus 로고    scopus 로고
    • Under-representation of patients 65 years of age or older in cancer- treatment trials
    • Hutchins LF, Unger JM, Crowley JJ, et al. Under-representation of patients 65 years of age or older in cancer- treatment trials. N Engl J Med. 1999;341:2061-2067.
    • (1999) N Engl J Med , vol.341 , pp. 2061-2067
    • Hutchins, L.F.1    Unger, J.M.2    Crowley, J.J.3
  • 6
    • 0038518557 scopus 로고    scopus 로고
    • Enrolment of older patients in cancer treatment trials in Canada: Why is age a barrier?
    • Yee KW, Pater JL, Pho L, et al. Enrolment of older patients in cancer treatment trials in Canada: why is age a barrier? J Clin Oncol. 2003;21:1618-1623.
    • (2003) J Clin Oncol , vol.21 , pp. 1618-1623
    • Yee, K.W.1    Pater, J.L.2    Pho, L.3
  • 7
    • 0028070572 scopus 로고
    • Representation of older patients in cancer treatment trials
    • Trimble EL, Carter CL, Cain D, et al. Representation of older patients in cancer treatment trials. Cancer. 1994;74(suppl 7):2208-2214.
    • (1994) Cancer , vol.74 , Issue.SUPPL. 7 , pp. 2208-2214
    • Trimble, E.L.1    Carter, C.L.2    Cain, D.3
  • 8
    • 16544371710 scopus 로고    scopus 로고
    • Talarico L, Chen G, Pazdur R. Enrolment of elderly patients in clinical trials for cancer drug registration: a 7-year experience by the US Food and Drug Administration. J Clin Oncol. 2004;22:4626-4631. Erratum in: J Clin Oncol. 2004;22:4811.
    • Talarico L, Chen G, Pazdur R. Enrolment of elderly patients in clinical trials for cancer drug registration: a 7-year experience by the US Food and Drug Administration. J Clin Oncol. 2004;22:4626-4631. Erratum in: J Clin Oncol. 2004;22:4811.
  • 9
    • 30744434127 scopus 로고    scopus 로고
    • Physiologic aspects of aging: Impact on cancer management and decision making, part I
    • Sawhney R, Sehl M, Naeim A. Physiologic aspects of aging: impact on cancer management and decision making, part I. Cancer J. 2005;11: 449-460.
    • (2005) Cancer J , vol.11 , pp. 449-460
    • Sawhney, R.1    Sehl, M.2    Naeim, A.3
  • 10
    • 30744449760 scopus 로고    scopus 로고
    • Physiologic aspects of aging: Impact on cancer management and decision making, part II
    • Sehl M, Sawhney R, Naeim A. Physiologic aspects of aging: impact on cancer management and decision making, part II. Cancer J. 2005;11:461-473.
    • (2005) Cancer J , vol.11 , pp. 461-473
    • Sehl, M.1    Sawhney, R.2    Naeim, A.3
  • 11
    • 26444541729 scopus 로고    scopus 로고
    • Physiology of aging: Relevance to symptom perception and treatment tolerance
    • Balducci L, Lyman GH, Ershler WB, et al, eds, 2nd ed. London; New York: Taylor & Francis;
    • Duthie ED. Physiology of aging: relevance to symptom perception and treatment tolerance. In: Balducci L, Lyman GH, Ershler WB, et al, eds. Comprehensive Geriatric Oncology. 2nd ed. London; New York: Taylor & Francis; 2004.
    • (2004) Comprehensive Geriatric Oncology
    • Duthie, E.D.1
  • 12
    • 0037108453 scopus 로고    scopus 로고
    • Familial aggregation of diabetes and hypertension in a case-control study of colorectal neoplasia
    • Brauer PM, McKeown-Eyssen GE, Jazmaji V, et al. Familial aggregation of diabetes and hypertension in a case-control study of colorectal neoplasia. Am J Epidemiol. 2002;156:702-713.
    • (2002) Am J Epidemiol , vol.156 , pp. 702-713
    • Brauer, P.M.1    McKeown-Eyssen, G.E.2    Jazmaji, V.3
  • 13
    • 0030730907 scopus 로고    scopus 로고
    • Associations of sedentary lifestyle, obesity, smoking, alcohol use, and diabetes with the risk of colorectal cancer
    • Le Marchand L, Wilkens LR, Kolonel LN, et al. Associations of sedentary lifestyle, obesity, smoking, alcohol use, and diabetes with the risk of colorectal cancer. Cancer Res. 1997;57:4787-4794.
    • (1997) Cancer Res , vol.57 , pp. 4787-4794
    • Le Marchand, L.1    Wilkens, L.R.2    Kolonel, L.N.3
  • 14
    • 0033577215 scopus 로고    scopus 로고
    • Prospective study of adult onset diabetes mellitus (type 2) and risk of colorectal cancer in women
    • Hu FB, Manson JE, Liu S, et al. Prospective study of adult onset diabetes mellitus (type 2) and risk of colorectal cancer in women. J Natl Cancer Inst. 1999;91:542-547.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 542-547
    • Hu, F.B.1    Manson, J.E.2    Liu, S.3
  • 15
    • 2942520997 scopus 로고    scopus 로고
    • Diabetes mellitus as a predictor of cancer mortality in a large cohort of US adults
    • Coughlin SS, Calle EE, Teras LR, et al. Diabetes mellitus as a predictor of cancer mortality in a large cohort of US adults. Am J Epidemiol. 2004;159:1160-1167.
    • (2004) Am J Epidemiol , vol.159 , pp. 1160-1167
    • Coughlin, S.S.1    Calle, E.E.2    Teras, L.R.3
  • 16
    • 0141992838 scopus 로고    scopus 로고
    • Cross-linked fibrin degradation products (D-dimer), plasma cytokines, and cognitive decline in communitydwelling elderly persons
    • Wilson CJ, Cohen HJ, Pieper CF. Cross-linked fibrin degradation products (D-dimer), plasma cytokines, and cognitive decline in communitydwelling elderly persons. J Am Geriatr Soc. 2003;51:1374-1381.
    • (2003) J Am Geriatr Soc , vol.51 , pp. 1374-1381
    • Wilson, C.J.1    Cohen, H.J.2    Pieper, C.F.3
  • 17
    • 17644368573 scopus 로고    scopus 로고
    • Interleukin-6: From basic science to medicine -40 years in immunology
    • Kishimoto T. Interleukin-6: from basic science to medicine -40 years in immunology. Annu Rev Immunol. 2005;23:1-21.
    • (2005) Annu Rev Immunol , vol.23 , pp. 1-21
    • Kishimoto, T.1
  • 18
    • 33646041638 scopus 로고    scopus 로고
    • C-reactive protein and other emerging blood biomarkers to optimize risk stratification of vulnerable patients
    • Tsimikas S, Willerson JT, Ridker PM. C-reactive protein and other emerging blood biomarkers to optimize risk stratification of vulnerable patients. J Am Coll Cardiol. 2006;47(suppl 8):C19-C31.
    • (2006) J Am Coll Cardiol , vol.47 , Issue.SUPPL. 8
    • Tsimikas, S.1    Willerson, J.T.2    Ridker, P.M.3
  • 19
    • 0025071032 scopus 로고
    • Altered pharmacokinetics in the elderly
    • Yuen GJ. Altered pharmacokinetics in the elderly. Clin Geriatr Med. 1990;6:257-267.
    • (1990) Clin Geriatr Med , vol.6 , pp. 257-267
    • Yuen, G.J.1
  • 20
    • 0031057556 scopus 로고    scopus 로고
    • Pharmacology of cancer chemotherapy in the older person
    • Baker SD, Grochow LB. Pharmacology of cancer chemotherapy in the older person. Clin Geriatr Med. 1997;13:169-183.
    • (1997) Clin Geriatr Med , vol.13 , pp. 169-183
    • Baker, S.D.1    Grochow, L.B.2
  • 21
    • 0031011748 scopus 로고    scopus 로고
    • Medication compliance as a feature in drug development
    • Kastrissios H, Blaschke TF. Medication compliance as a feature in drug development. Annu Rev Pharmacol Toxicol. 1997;37:451-475.
    • (1997) Annu Rev Pharmacol Toxicol , vol.37 , pp. 451-475
    • Kastrissios, H.1    Blaschke, T.F.2
  • 22
    • 0030931530 scopus 로고    scopus 로고
    • Ageing and pharmacology
    • Vestal RE. Ageing and pharmacology. Cancer. 1997;80:1302-1310.
    • (1997) Cancer , vol.80 , pp. 1302-1310
    • Vestal, R.E.1
  • 23
    • 42149137765 scopus 로고    scopus 로고
    • Avorn J, Gurwitz JH. Principles of pharmacology. In Cassel CK, Cohen HJ, Larson EB, et al, Geriatric Medicine. 3rd ed. New York: Springer-Verlag; 1996.
    • Avorn J, Gurwitz JH. Principles of pharmacology. In Cassel CK, Cohen HJ, Larson EB, et al, Geriatric Medicine. 3rd ed. New York: Springer-Verlag; 1996.
  • 24
    • 19944427867 scopus 로고    scopus 로고
    • Factors affecting cytochrome P-450 3A activity in cancer patients
    • Baker SD, van Schaik RH, Rivory LP, et al. Factors affecting cytochrome P-450 3A activity in cancer patients. Clin Cancer Res. 2004; 10:8341-8350.
    • (2004) Clin Cancer Res , vol.10 , pp. 8341-8350
    • Baker, S.D.1    van Schaik, R.H.2    Rivory, L.P.3
  • 25
    • 0026708362 scopus 로고
    • Effect of age and gender on the activity of human hepatic CYP3A
    • Hunt CM, Westerkam WR, Stave GM. Effect of age and gender on the activity of human hepatic CYP3A. Biochem Pharmacol. 1992;44:275-283.
    • (1992) Biochem Pharmacol , vol.44 , pp. 275-283
    • Hunt, C.M.1    Westerkam, W.R.2    Stave, G.M.3
  • 26
    • 0035124031 scopus 로고    scopus 로고
    • Race but not age affects erythromycin breath test results in older hypertensive men
    • Schwartz JB. Race but not age affects erythromycin breath test results in older hypertensive men. J Clin Pharmacol. 2001;41:324-329.
    • (2001) J Clin Pharmacol , vol.41 , pp. 324-329
    • Schwartz, J.B.1
  • 27
    • 0021910427 scopus 로고
    • Longitudinal studies on the rate of decline in renal function with age
    • Lindeman RD, Tobin J, Shock NW. Longitudinal studies on the rate of decline in renal function with age. J Am Geriatr Soc. 1985;33:278-285.
    • (1985) J Am Geriatr Soc , vol.33 , pp. 278-285
    • Lindeman, R.D.1    Tobin, J.2    Shock, N.W.3
  • 28
    • 1242272766 scopus 로고    scopus 로고
    • Renal function in the elderly (>70 years old) measured by means of iohexol clearance, serum creatinine, serum urea and estimated clearance
    • Fehrman-Ekholm I, Skeppholm L. Renal function in the elderly (>70 years old) measured by means of iohexol clearance, serum creatinine, serum urea and estimated clearance. Scand J Urol Nephrol. 2004;38:73-77.
    • (2004) Scand J Urol Nephrol , vol.38 , pp. 73-77
    • Fehrman-Ekholm, I.1    Skeppholm, L.2
  • 29
    • 2442686588 scopus 로고    scopus 로고
    • Can creatinine clearance be accurately predicted by formulae in octogenarian in-patients?
    • Rimon E, Kagansky N, Cojocaru L, et al. Can creatinine clearance be accurately predicted by formulae in octogenarian in-patients? QJM. 2004;97:281-287.
    • (2004) QJM , vol.97 , pp. 281-287
    • Rimon, E.1    Kagansky, N.2    Cojocaru, L.3
  • 30
    • 0036229778 scopus 로고    scopus 로고
    • Creatinine clearance, Cockcroft-Gault formula and cystatin C: Estimators of true glomerular filtration rate in the elderly?
    • Burkhardt H, Bojarsky G, Gretz N, et al. Creatinine clearance, Cockcroft-Gault formula and cystatin C: estimators of true glomerular filtration rate in the elderly? Gerontology. 2002;48:140-146.
    • (2002) Gerontology , vol.48 , pp. 140-146
    • Burkhardt, H.1    Bojarsky, G.2    Gretz, N.3
  • 31
    • 1342267612 scopus 로고    scopus 로고
    • Evaluation of the Cockroft- Gault, Jelliffe and Wright formulae in estimating renal function in elderly cancer patients
    • Marx GM, Blake GM, Galani E, et al. Evaluation of the Cockroft- Gault, Jelliffe and Wright formulae in estimating renal function in elderly cancer patients. Ann Oncol. 2004;15:291-295.
    • (2004) Ann Oncol , vol.15 , pp. 291-295
    • Marx, G.M.1    Blake, G.M.2    Galani, E.3
  • 32
    • 0037451920 scopus 로고    scopus 로고
    • Adverse drug events in ambulatory care
    • Gandhi TK, Weingart SN, Borus J, et al. Adverse drug events in ambulatory care. N Engl J Med. 2003;348:1556-1564.
    • (2003) N Engl J Med , vol.348 , pp. 1556-1564
    • Gandhi, T.K.1    Weingart, S.N.2    Borus, J.3
  • 33
    • 0242320969 scopus 로고    scopus 로고
    • Understanding and preventing drug interactions in elderly patients
    • Delafuente JC. Understanding and preventing drug interactions in elderly patients. Crit Rev Oncol Hematol. 2003;48:133-143.
    • (2003) Crit Rev Oncol Hematol , vol.48 , pp. 133-143
    • Delafuente, J.C.1
  • 34
    • 33646928882 scopus 로고    scopus 로고
    • Incidence and predictors of all and preventable adverse drug reactions in frail elderly persons after hospital stay
    • Hanlon JT, Pieper CF, Hajjar ER, et al. Incidence and predictors of all and preventable adverse drug reactions in frail elderly persons after hospital stay. J Gerontol A Biol Sci Med Sci. 2006;61:511-515.
    • (2006) J Gerontol A Biol Sci Med Sci , vol.61 , pp. 511-515
    • Hanlon, J.T.1    Pieper, C.F.2    Hajjar, E.R.3
  • 35
    • 0035852040 scopus 로고    scopus 로고
    • Potentially inappropriate medication use in the community-dwelling elderly: Findings from the 1996 Medical Expenditure Panel Survey
    • Zhan C, Sangl J, Bierman AS, et al. Potentially inappropriate medication use in the community-dwelling elderly: findings from the 1996 Medical Expenditure Panel Survey. JAMA. 2001;286:2823-2829.
    • (2001) JAMA , vol.286 , pp. 2823-2829
    • Zhan, C.1    Sangl, J.2    Bierman, A.S.3
  • 36
    • 0347985317 scopus 로고    scopus 로고
    • Crawford J, Dale DC, Lyman GH. Chemotherapy-induced neutropenia: risks, consequences, and new directions for its management. Cancer. 2004;100:228-237. Erratum in: Cancer. 2004;100:1993-1994.
    • Crawford J, Dale DC, Lyman GH. Chemotherapy-induced neutropenia: risks, consequences, and new directions for its management. Cancer. 2004;100:228-237. Erratum in: Cancer. 2004;100:1993-1994.
  • 37
    • 24044454968 scopus 로고    scopus 로고
    • Use of comprehensive geriatric assessment in older cancer patients: Recommendations from the task force on CGA of the International Society of Geriatric Oncology (SIOG)
    • Extermann M, Aapro M, Bernabei R, et al. Use of comprehensive geriatric assessment in older cancer patients: recommendations from the task force on CGA of the International Society of Geriatric Oncology (SIOG). Crit Rev Oncol Hematol. 2005;55:241-252. 37.
    • (2005) Crit Rev Oncol Hematol , vol.55 , Issue.241-252 , pp. 37
    • Extermann, M.1    Aapro, M.2    Bernabei, R.3
  • 38
    • 27244441470 scopus 로고    scopus 로고
    • Developing a cancer-specific geriatric assessment: A feasibility study
    • Hurria A, Gupta S, Zauderer M, et al. Developing a cancer-specific geriatric assessment: a feasibility study. Cancer. 2005;104:1998-2005.
    • (2005) Cancer , vol.104 , pp. 1998-2005
    • Hurria, A.1    Gupta, S.2    Zauderer, M.3
  • 39
    • 0343080998 scopus 로고    scopus 로고
    • A prospective pharmacologic evaluation of age-related toxicity of adjuvant chemotherapy in women with breast cancer
    • Dees EC, O'Reilly S, Goodman SN, et al: A prospective pharmacologic evaluation of age-related toxicity of adjuvant chemotherapy in women with breast cancer. Cancer Invest 18:521-529, 2000.
    • (2000) Cancer Invest , vol.18 , pp. 521-529
    • Dees, E.C.1    O'Reilly, S.2    Goodman, S.N.3
  • 40
    • 0029365836 scopus 로고
    • Physiological aspects of aging. Implications for the treatment of cancer
    • Lichtman SM. Physiological aspects of aging. Implications for the treatment of cancer. Drugs Aging. 1995;7:212-225.
    • (1995) Drugs Aging , vol.7 , pp. 212-225
    • Lichtman, S.M.1
  • 42
    • 0036137077 scopus 로고    scopus 로고
    • Carboplatin dosing formulae: Gender bias and the use of creatinine-based methodologies
    • Calvert AH, Egorin MJ. Carboplatin dosing formulae: gender bias and the use of creatinine-based methodologies. Eur J Cancer. 2002;38:11-16.
    • (2002) Eur J Cancer , vol.38 , pp. 11-16
    • Calvert, A.H.1    Egorin, M.J.2
  • 44
    • 0033045023 scopus 로고    scopus 로고
    • High inter- and intrapatient variation in 5-fluorouracil plasma concentrations during a prolonged drug infusion
    • Takimoto CH, Yee LK, Venzon DJ, et al: High inter- and intrapatient variation in 5-fluorouracil plasma concentrations during a prolonged drug infusion. Clin Cancer Res 5:1347-1352, 1999
    • (1999) Clin Cancer Res , vol.5 , pp. 1347-1352
    • Takimoto, C.H.1    Yee, L.K.2    Venzon, D.J.3
  • 45
    • 33646338675 scopus 로고    scopus 로고
    • Cancer in the elderly population: The protection racket
    • Raghavan D, Suh T: Cancer in the elderly population: The protection racket. J Clin Oncol 24: 1795-1796, 2006.
    • (2006) J Clin Oncol , vol.24 , pp. 1795-1796
    • Raghavan, D.1    Suh, T.2
  • 46
    • 0032729847 scopus 로고    scopus 로고
    • Bioequivalence of two tablet formulations of capecitabine and exploration of age, gender, body surface area, and creatinine clearance as factors influencing systemic exposure in cancer patients
    • Cassidy J, Twelves C, Cameron D, et al: Bioequivalence of two tablet formulations of capecitabine and exploration of age, gender, body surface area, and creatinine clearance as factors influencing systemic exposure in cancer patients. Cancer Chemother Pharmacol 44:453-460, 1999.
    • (1999) Cancer Chemother Pharmacol , vol.44 , pp. 453-460
    • Cassidy, J.1    Twelves, C.2    Cameron, D.3
  • 47
    • 0344514147 scopus 로고    scopus 로고
    • Pharmacology of anticancer drugs in the elderly population
    • Wildiers H, Highley MS, de Bruijn EA, et al: Pharmacology of anticancer drugs in the elderly population. Clin Pharmacokinet 42:1213-1242, 2003.
    • (2003) Clin Pharmacokinet , vol.42 , pp. 1213-1242
    • Wildiers, H.1    Highley, M.S.2    de Bruijn, E.A.3
  • 48
    • 0035846320 scopus 로고    scopus 로고
    • A pooled analysis of adjuvant chemotherapy for resected colon cancer in elderly patients
    • Sargent DJ, Goldberg RM, Jacobson SD, et al: A pooled analysis of adjuvant chemotherapy for resected colon cancer in elderly patients. N Engl J Med 345:1091-1097, 2001.
    • (2001) N Engl J Med , vol.345 , pp. 1091-1097
    • Sargent, D.J.1    Goldberg, R.M.2    Jacobson, S.D.3
  • 49
    • 4644288273 scopus 로고    scopus 로고
    • Efficacy of 5-fluorouracil-based chemotherapy in elderly patients with metastatic colorectal cancer: A pooled analysis of clinical trials
    • Folprecht G, Cunningham D, Ross P, et al:Efficacy of 5-fluorouracil-based chemotherapy in elderly patients with metastatic colorectal cancer: A pooled analysis of clinical trials. Ann Oncol 15:1330-1338, 2004.
    • (2004) Ann Oncol , vol.15 , pp. 1330-1338
    • Folprecht, G.1    Cunningham, D.2    Ross, P.3
  • 50
    • 2942525789 scopus 로고    scopus 로고
    • Taxanes in elderly breast cancer patients
    • Wildiers H, Paridaens R. Taxanes in elderly breast cancer patients. Cancer Treat Rev. 2004;30:333-342.
    • (2004) Cancer Treat Rev , vol.30 , pp. 333-342
    • Wildiers, H.1    Paridaens, R.2


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