-
1
-
-
33746371464
-
Protection of the kidney by thiazolidinediones: An assessment from bench to bedside
-
Sarafidis PA, Bakris GL. Protection of the kidney by thiazolidinediones: an assessment from bench to bedside. Kidney Int 2006; 70:1223-1233.
-
(2006)
Kidney Int
, vol.70
, pp. 1223-1233
-
-
Sarafidis, P.A.1
Bakris, G.L.2
-
2
-
-
0032540012
-
PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL
-
Tontonoz P, Nagy L, Alvarez JG, et al. PPARgamma promotes monocyte/macrophage differentiation and uptake of oxidized LDL. Cell 1998; 93:241-252.
-
(1998)
Cell
, vol.93
, pp. 241-252
-
-
Tontonoz, P.1
Nagy, L.2
Alvarez, J.G.3
-
3
-
-
0035046542
-
Peroxisome proliferator-activated receptor-gamma agonist troglitazone protects against nondiabetic glomerulosclerosis in rats
-
Ma LJ, Marcantoni C, Linton MF, et al. Peroxisome proliferator-activated receptor-gamma agonist troglitazone protects against nondiabetic glomerulosclerosis in rats. Kidney Int 2001; 59:1899-1910.
-
(2001)
Kidney Int
, vol.59
, pp. 1899-1910
-
-
Ma, L.J.1
Marcantoni, C.2
Linton, M.F.3
-
4
-
-
0035126947
-
Effects of troglitazone and temocapril in spontaneously hypertensive rats with chronic renal failure
-
Yoshida K, Kohzuki M, Xu HL, et al. Effects of troglitazone and temocapril in spontaneously hypertensive rats with chronic renal failure. J Hypertens 2001; 19:503-510.
-
(2001)
J Hypertens
, vol.19
, pp. 503-510
-
-
Yoshida, K.1
Kohzuki, M.2
Xu, H.L.3
-
5
-
-
33646686362
-
Peroxisome proliferator-activated receptor-gamma agonist is protective in podocyte injury-associated sclerosis
-
Yang HC, Ma LJ, Ma J, Fogo AB. Peroxisome proliferator-activated receptor-gamma agonist is protective in podocyte injury-associated sclerosis. Kidney Int 2006; 69:1756-1764.
-
(2006)
Kidney Int
, vol.69
, pp. 1756-1764
-
-
Yang, H.C.1
Ma, L.J.2
Ma, J.3
Fogo, A.B.4
-
6
-
-
0036098955
-
Microangiopathic injury and augmented PAI-1 in human diabetic nephropathy
-
Paueksakon P, Revelo MP, Ma LJ, et al. Microangiopathic injury and augmented PAI-1 in human diabetic nephropathy. Kidney Int 2002; 61:2142-2148.
-
(2002)
Kidney Int
, vol.61
, pp. 2142-2148
-
-
Paueksakon, P.1
Revelo, M.P.2
Ma, L.J.3
-
7
-
-
27944490844
-
Chronic allograft nephropathy: Expression and localization of PAI-1 and PPAR-gamma
-
Revelo MP, Federspiel C, Helderman H, Fogo AB. Chronic allograft nephropathy: expression and localization of PAI-1 and PPAR-gamma. Nephrol Dial Transplant 2005; 20:2812-2819.
-
(2005)
Nephrol Dial Transplant
, vol.20
, pp. 2812-2819
-
-
Revelo, M.P.1
Federspiel, C.2
Helderman, H.3
Fogo, A.B.4
-
8
-
-
34250013383
-
PPAR-gamma agonist protects podocytes from injury
-
The beneficial effect of PPARγ agonists on podocyte injury in vitro is shown
-
Kanjanabuch T, Ma LJ, Chen J, et al. PPAR-gamma agonist protects podocytes from injury. Kidney Int 2007; 71:1232-1239. The beneficial effect of PPARγ agonists on podocyte injury in vitro is shown.
-
(2007)
Kidney Int
, vol.71
, pp. 1232-1239
-
-
Kanjanabuch, T.1
Ma, L.J.2
Chen, J.3
-
9
-
-
33748335467
-
Thiazolidinediones ameliorate diabetic nephropathy via cell cycle-dependent mechanisms
-
Okada T, Wada J, Hida K, et al. Thiazolidinediones ameliorate diabetic nephropathy via cell cycle-dependent mechanisms. Diabetes 2006; 55:1666-1677.
-
(2006)
Diabetes
, vol.55
, pp. 1666-1677
-
-
Okada, T.1
Wada, J.2
Hida, K.3
-
10
-
-
0346101487
-
Divergent effects of low versus high dose anti-TGF-beta antibody in puromycin aminonucleoside nephropathy in rats
-
Ma LJ, Jha S, Ling H, et al. Divergent effects of low versus high dose anti-TGF-beta antibody in puromycin aminonucleoside nephropathy in rats. Kidney Int 2004; 65:106-115.
-
(2004)
Kidney Int
, vol.65
, pp. 106-115
-
-
Ma, L.J.1
Jha, S.2
Ling, H.3
-
11
-
-
0038205926
-
Add-on anti-TGF-beta antibody to ACE inhibitor arrests progressive diabetic nephropathy in the rat
-
Benigni A, Zoja C, Corna D, et al. Add-on anti-TGF-beta antibody to ACE inhibitor arrests progressive diabetic nephropathy in the rat. J Am Soc Nephrol 2003; 14:1816-1824.
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 1816-1824
-
-
Benigni, A.1
Zoja, C.2
Corna, D.3
-
12
-
-
34147213227
-
Thiazolidinedione ameliorates renal injury in experimental diabetic rats through anti-inflammatory effects mediated by inhibition of NF-kappaB activation
-
This article provides evidence for the beneficial effects of PPARγ agonists in decreasing inflammation and inhibiting nuclear factor κB in diabetic injury
-
Ohga S, Shikata K, Yozai K, et al. Thiazolidinedione ameliorates renal injury in experimental diabetic rats through anti-inflammatory effects mediated by inhibition of NF-kappaB activation. Am J Physiol Renal Physiol 2007; 292:F1141-F1150. This article provides evidence for the beneficial effects of PPARγ agonists in decreasing inflammation and inhibiting nuclear factor κB in diabetic injury.
-
(2007)
Am J Physiol Renal Physiol
, vol.292
-
-
Ohga, S.1
Shikata, K.2
Yozai, K.3
-
13
-
-
36649011357
-
Thiazolidinediones provide better renoprotection than insulin in an obese, hypertensive type II diabetic rat model
-
This study provides evidence to support the actions of PPARγ agonists beyond glycemic control in vivo
-
Ohtomo S, Izuhara Y, Takizawa S, et al. Thiazolidinediones provide better renoprotection than insulin in an obese, hypertensive type II diabetic rat model. Kidney Int 2007; 72:1512-1519. This study provides evidence to support the actions of PPARγ agonists beyond glycemic control in vivo.
-
(2007)
Kidney Int
, vol.72
, pp. 1512-1519
-
-
Ohtomo, S.1
Izuhara, Y.2
Takizawa, S.3
-
14
-
-
23044437024
-
Pioglitazone attenuates TGF-beta(1)-induction of fibronectin synthesis and its splicing variant in human mesangial cells via activation of peroxisome proliferator-activated receptor (PPAR)gamma
-
Maeda A, Horikoshi S, Gohda T, et al. Pioglitazone attenuates TGF-beta(1)-induction of fibronectin synthesis and its splicing variant in human mesangial cells via activation of peroxisome proliferator-activated receptor (PPAR)gamma. Cell Biol Int 2005; 29:422-428.
-
(2005)
Cell Biol Int
, vol.29
, pp. 422-428
-
-
Maeda, A.1
Horikoshi, S.2
Gohda, T.3
-
15
-
-
0035098304
-
Expression and function of peroxisome proliferator-activated receptor-gamma in mesangial cells
-
Nicholas SB, Kawano Y, Wakino S, et al. Expression and function of peroxisome proliferator-activated receptor-gamma in mesangial cells. Hypertension 2001; 37:722-727.
-
(2001)
Hypertension
, vol.37
, pp. 722-727
-
-
Nicholas, S.B.1
Kawano, Y.2
Wakino, S.3
-
16
-
-
20544469044
-
Pioglitazone inhibits cell growth and reduces matrix production in human kidney fibroblasts
-
Zafiriou S, Stanners SR, Saad S, et al. Pioglitazone inhibits cell growth and reduces matrix production in human kidney fibroblasts. J Am Soc Nephrol 2005; 16:638-645.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 638-645
-
-
Zafiriou, S.1
Stanners, S.R.2
Saad, S.3
-
17
-
-
33645454825
-
Hepatocyte growth factor is a downstream effector that mediates the antifibrotic action of peroxisome proliferator-activated receptor-gamma agonists
-
Li Y, Wen X, Spataro BC, et al. Hepatocyte growth factor is a downstream effector that mediates the antifibrotic action of peroxisome proliferator-activated receptor-gamma agonists. J Am Soc Nephrol 2006; 17:54-65.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 54-65
-
-
Li, Y.1
Wen, X.2
Spataro, B.C.3
-
18
-
-
33750825285
-
Molecular activation of PPARgamma by angiotensin II type 1-receptor antagonists
-
Erbe DV, Gartrell K, Zhang YL, et al. Molecular activation of PPARgamma by angiotensin II type 1-receptor antagonists. Vascul Pharmacol 2006; 45:154-162.
-
(2006)
Vascul Pharmacol
, vol.45
, pp. 154-162
-
-
Erbe, D.V.1
Gartrell, K.2
Zhang, Y.L.3
-
19
-
-
42149184556
-
Macrophages deficient in peroxisome proliferators-activated receptor-γ accelerate angiotensin II-induced atherosclerosis [abstract]
-
Suganuma E, Babaev V, Fogo A, et al. Macrophages deficient in peroxisome proliferators-activated receptor-γ accelerate angiotensin II-induced atherosclerosis [abstract]. J Am Soc Nephrol 2004; 15:5A.
-
(2004)
J Am Soc Nephrol
, vol.15
-
-
Suganuma, E.1
Babaev, V.2
Fogo, A.3
-
20
-
-
34250212715
-
Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
-
Nissen SE, Wolski K. Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N Engl J Med 2007; 356:2457-2471.
-
(2007)
N Engl J Med
, vol.356
, pp. 2457-2471
-
-
Nissen, S.E.1
Wolski, K.2
-
21
-
-
35648969638
-
Does rosiglitazone increase cardiovascular outcomes?
-
Doggrell SA. Does rosiglitazone increase cardiovascular outcomes? Expert Opin Pharmacother 2007; 8:2665-2669.
-
(2007)
Expert Opin Pharmacother
, vol.8
, pp. 2665-2669
-
-
Doggrell, S.A.1
-
22
-
-
36448964472
-
Is rosiglitazone associated with increased risk for cardiovascular events? Nat Clin Pract
-
Hanefeld M. Is rosiglitazone associated with increased risk for cardiovascular events? Nat Clin Pract Cardiovasc Med 2007; 4:648-649.
-
(2007)
Cardiovasc Med
, vol.4
, pp. 648-649
-
-
Hanefeld, M.1
-
23
-
-
34447530707
-
Renoprotection provided by losartan in combination with pioglitazone is superior to renoprotection provided by losartan alone in patients with type 2 diabetic nephropathy
-
Improved renal function with lower serum creatinine and proteinuria was observed in patients with diabetes with a combination of ARB and PPARγ agonist, linked to improved glycemic control
-
Jin HM, Pan Y. Renoprotection provided by losartan in combination with pioglitazone is superior to renoprotection provided by losartan alone in patients with type 2 diabetic nephropathy. Kidney Blood Press Res 2007; 30:203-211. Improved renal function with lower serum creatinine and proteinuria was observed in patients with diabetes with a combination of ARB and PPARγ agonist, linked to improved glycemic control.
-
(2007)
Kidney Blood Press Res
, vol.30
, pp. 203-211
-
-
Jin, H.M.1
Pan, Y.2
-
24
-
-
10744228409
-
Prevention of obesity and insulin resistance in mice lacking plasminogen activator inhibitor 1
-
Ma LJ, Mao SL, Taylor KL, et al. Prevention of obesity and insulin resistance in mice lacking plasminogen activator inhibitor 1. Diabetes 2004; 53:336-346.
-
(2004)
Diabetes
, vol.53
, pp. 336-346
-
-
Ma, L.J.1
Mao, S.L.2
Taylor, K.L.3
-
25
-
-
36249006990
-
Rosiglitazone decreases albuminuria in type 2 diabetic patients
-
These authors makes important observations in humans with diabetes of improved renal function linked to PPARγ agonists, independent of glycemic effects, possibly mediated by effects on tumor necrosis factor-α and adiponectin
-
Miyazaki Y, Cersosimo E, Triplitt C, DeFronzo RA. Rosiglitazone decreases albuminuria in type 2 diabetic patients. Kidney Int 2007; 72:1367-1373. These authors makes important observations in humans with diabetes of improved renal function linked to PPARγ agonists, independent of glycemic effects, possibly mediated by effects on tumor necrosis factor-α and adiponectin.
-
(2007)
Kidney Int
, vol.72
, pp. 1367-1373
-
-
Miyazaki, Y.1
Cersosimo, E.2
Triplitt, C.3
DeFronzo, R.A.4
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