Intracellular delivery of acetyl-histone peptides inhibits native bromodomain-chromatin interactions and impairs mitotic progression

FEBS Letters

Volumn 582, Issue 10, 2008, Pages 1501-1507

  Nishiyama, Akira ^a   Mochizuki, Kazuki ^a   Mueller, Florian ^b   Karpova, Tatiana ^b   McNally, James G ^b   Ozato, Keiko ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Acetyl histone tail; Brd4; Bromodomain; FRAP; Peptide transduction

Indexed keywords

ACETYL HISTONE PEPTIDE DERIVATIVE; HISTONE H4; PEPTIDE DERIVATIVE; PROTEIN BRD4; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BLEACHING; CELL CULTURE; CELL GROWTH; CHROMATIN; CHROMOSOME; CONTROLLED STUDY; IN VIVO STUDY; MITOSIS; NONHUMAN; PRIORITY JOURNAL;

ACETYLATION; AMINO ACID SEQUENCE; ANIMALS; CHROMATIN; HISTONES; MICE; MITOSIS; MOLECULAR SEQUENCE DATA; NIH 3T3 CELLS; NUCLEAR PROTEINS; PEPTIDES; PROTEIN STRUCTURE, TERTIARY; RNA, SMALL INTERFERING; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; TRANSCRIPTION FACTORS;

HUMAN IMMUNODEFICIENCY VIRUS;

EID: 42049117592     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2008.03.044     Document Type: Article

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