-
1
-
-
15244350599
-
Variations of CYP3A activity induced by antiretroviral treatment in HIV-1 infected patients
-
Fellay J, Marzolini C, Decosterd L, et al. Variations of CYP3A activity induced by antiretroviral treatment in HIV-1 infected patients. Eur J Clin Pharmacol 2000; 60:865-873.
-
(2000)
Eur J Clin Pharmacol
, vol.60
, pp. 865-873
-
-
Fellay, J.1
Marzolini, C.2
Decosterd, L.3
-
2
-
-
0033846819
-
Variability in activity of hepatic CYP3A4 in patients infected with HIV
-
Slain D, Pakyz A, Israel DS, et al. Variability in activity of hepatic CYP3A4 in patients infected with HIV. Pharmacotherapy 2000; 20:898-907.
-
(2000)
Pharmacotherapy
, vol.20
, pp. 898-907
-
-
Slain, D.1
Pakyz, A.2
Israel, D.S.3
-
3
-
-
0029561243
-
Alterations in gastric acidity in patients infected with human immunodeficiency virus
-
Welage LS, Carver PL, Revankar S, et al. Alterations in gastric acidity in patients infected with human immunodeficiency virus. Clin Infect Dis 1995; 21:1431-1438.
-
(1995)
Clin Infect Dis
, vol.21
, pp. 1431-1438
-
-
Welage, L.S.1
Carver, P.L.2
Revankar, S.3
-
4
-
-
0001931449
-
Alpha-1-acid glycoprotein concentrations in HIV disease. Implications for treatment with protease inhibitors
-
Merry C, Mulcahy F, Lloyd J, et al. Alpha-1-acid glycoprotein concentrations in HIV disease. Implications for treatment with protease inhibitors. AIDS 1996; 10:21.
-
(1996)
AIDS
, vol.10
, pp. 21
-
-
Merry, C.1
Mulcahy, F.2
Lloyd, J.3
-
5
-
-
42049118101
-
-
Bristol-Myers Squibb Co, Princeton, New Jersey, USA: Bristol-Myers Squibb Co
-
Bristol-Myers Squibb Co.: Reyataz® (atazanavir): product information. Princeton, New Jersey, USA: Bristol-Myers Squibb Co.; 2007.
-
(2007)
Reyataz® (atazanavir): Product information
-
-
-
6
-
-
25144448034
-
Clinical pharmacokinetics and summary of efficacy and tolerability of atazanavir
-
Le Tiec C, Barrail A, Goujard C, et al. Clinical pharmacokinetics and summary of efficacy and tolerability of atazanavir. Clin Pharmacokinet 2005; 44:1035-1050.
-
(2005)
Clin Pharmacokinet
, vol.44
, pp. 1035-1050
-
-
Le Tiec, C.1
Barrail, A.2
Goujard, C.3
-
7
-
-
27544433097
-
Proton pump inhibitors do not reduce atazanavir concentrations in HIV-infected patients treated with ritonavir-boosted atazanavir
-
Guiard-Schmid JB, Poirier JM, Bonnard P, et al. Proton pump inhibitors do not reduce atazanavir concentrations in HIV-infected patients treated with ritonavir-boosted atazanavir. AIDS 2005; 19:1937-1938.
-
(2005)
AIDS
, vol.19
, pp. 1937-1938
-
-
Guiard-Schmid, J.B.1
Poirier, J.M.2
Bonnard, P.3
-
8
-
-
34548572319
-
Tenofovir comedication does not impair the steady-state pharmacokinetics of ritonavir-boosted atazanavir in HIV-1-infected adults
-
von Hentig N, Dauer B, Haberl A, et al. Tenofovir comedication does not impair the steady-state pharmacokinetics of ritonavir-boosted atazanavir in HIV-1-infected adults. Eur J Clin Pharmacol 2007; 63:935-940.
-
(2007)
Eur J Clin Pharmacol
, vol.63
, pp. 935-940
-
-
von Hentig, N.1
Dauer, B.2
Haberl, A.3
-
9
-
-
34247175708
-
Pharmacokinetics of saquinavir, atazanavir, and ritonavir in a twice-daily boosted double-protease inhibitor regimen
-
von Hentig N, Muller A, Rottmann C, et al. Pharmacokinetics of saquinavir, atazanavir, and ritonavir in a twice-daily boosted double-protease inhibitor regimen. Antimicrob Agents Chemother 2007; 51:1431-1439.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 1431-1439
-
-
von Hentig, N.1
Muller, A.2
Rottmann, C.3
-
10
-
-
33745792782
-
Virological responses to atazanavir-ritonavir-based regimens: Resistance-substitutions score and pharmacokinetic parameters (Reyaphar study)
-
Pellegrin I, Breilh D, Ragnaud JM, et al. Virological responses to atazanavir-ritonavir-based regimens: resistance-substitutions score and pharmacokinetic parameters (Reyaphar study). Antivir Ther 2006; 11:421-429.
-
(2006)
Antivir Ther
, vol.11
, pp. 421-429
-
-
Pellegrin, I.1
Breilh, D.2
Ragnaud, J.M.3
-
11
-
-
33646873968
-
Atazanavir and lopinavir/ritonavir: Pharmacokinetics, safety and efficacy of a promising double-boosted protease inhibitor regimen
-
Ribera E, Azuaje C, Lopez RM, et al. Atazanavir and lopinavir/ritonavir: pharmacokinetics, safety and efficacy of a promising double-boosted protease inhibitor regimen. AIDS 2006; 20:1131-1139.
-
(2006)
AIDS
, vol.20
, pp. 1131-1139
-
-
Ribera, E.1
Azuaje, C.2
Lopez, R.M.3
-
12
-
-
33644513115
-
Ritonavir-boosted atazanavir-lopinavir combination: A pharmacokinetic interaction study of total, unbound plasma and cellular exposures
-
Colombo S, Buclin T, Franc C, et al. Ritonavir-boosted atazanavir-lopinavir combination: a pharmacokinetic interaction study of total, unbound plasma and cellular exposures. Antivir Ther 2006; 11:53-62.
-
(2006)
Antivir Ther
, vol.11
, pp. 53-62
-
-
Colombo, S.1
Buclin, T.2
Franc, C.3
-
13
-
-
2542502584
-
Interactions between atazanavir-ritonavir and tenofovir in heavily pretreated human immunodeficiency virus-infected patients
-
Taburet AM, Piketty C, Chazallon C, et al. Interactions between atazanavir-ritonavir and tenofovir in heavily pretreated human immunodeficiency virus-infected patients. Antimicrob Agents Chemother 2004; 48:2091-2096.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 2091-2096
-
-
Taburet, A.M.1
Piketty, C.2
Chazallon, C.3
-
14
-
-
34548299142
-
Steady-state pharmacokinetics of oncedaily fosamprenavir/ritonavir and atazanavir/ritonavir alone and in combination with 20 mg omeprazole in healthy volunteers
-
Luber AD, Brower R, Kim D, et al. Steady-state pharmacokinetics of oncedaily fosamprenavir/ritonavir and atazanavir/ritonavir alone and in combination with 20 mg omeprazole in healthy volunteers. HIV Med 2007; 8:457-464.
-
(2007)
HIV Med
, vol.8
, pp. 457-464
-
-
Luber, A.D.1
Brower, R.2
Kim, D.3
-
15
-
-
34249890243
-
Beneficial pharmacokinetic interaction between atazanavir and lopinavir/ritonavir
-
Pham PA, Flexner C, Parsons T, et al. Beneficial pharmacokinetic interaction between atazanavir and lopinavir/ritonavir. J Acquir Immune Defic Syndr 2007; 45:201-205.
-
(2007)
J Acquir Immune Defic Syndr
, vol.45
, pp. 201-205
-
-
Pham, P.A.1
Flexner, C.2
Parsons, T.3
-
16
-
-
35148851106
-
Interaction between buprenorphine and atazanavir or atazanavir/ritonavir
-
McCance-Katz EF, Moody DE, Morse GD, et al. Interaction between buprenorphine and atazanavir or atazanavir/ritonavir. Drug Alcohol Depend 2007; 91:269-278.
-
(2007)
Drug Alcohol Depend
, vol.91
, pp. 269-278
-
-
McCance-Katz, E.F.1
Moody, D.E.2
Morse, G.D.3
-
17
-
-
33749510684
-
Effect of rifampin on steady-state pharmacokinetics of atazanavir with ritonavir in healthy volunteers
-
Burger DM, Agarwala S, Child M, et al. Effect of rifampin on steady-state pharmacokinetics of atazanavir with ritonavir in healthy volunteers. Antimicrob Agents Chemother 2006; 50:3336-3342.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, pp. 3336-3342
-
-
Burger, D.M.1
Agarwala, S.2
Child, M.3
-
18
-
-
42049106892
-
-
th European AIDS Conference (EACS); 24-27 October 2007; Madrid, Spain. Paris, France: European AIDS Clinical Society; 2007.
-
th European AIDS Conference (EACS); 24-27 October 2007; Madrid, Spain. Paris, France: European AIDS Clinical Society; 2007.
-
-
-
-
19
-
-
34547768666
-
Abacavir plasma pharmacokinetics in the absence and presence of atazanavir/ritonavir or lopinavir/ritonavir and vice versa in HIV-infected patients
-
Waters LJ, Moyle G, Bonora S, et al. Abacavir plasma pharmacokinetics in the absence and presence of atazanavir/ritonavir or lopinavir/ritonavir and vice versa in HIV-infected patients. Antivir Ther 2007; 12:825-830.
-
(2007)
Antivir Ther
, vol.12
, pp. 825-830
-
-
Waters, L.J.1
Moyle, G.2
Bonora, S.3
-
20
-
-
28844450388
-
Simultaneous determination of HIV protease inhibitors amprenavir, atazanavir, indinavir, lopinavir, nelfinavir, ritonavir and saquinavir in human plasma by high-performance liquid chromatography-tandem mass spectrometry
-
Dickinson L, Robinson L, Tjia J, et al. Simultaneous determination of HIV protease inhibitors amprenavir, atazanavir, indinavir, lopinavir, nelfinavir, ritonavir and saquinavir in human plasma by high-performance liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2005; 829:82-90.
-
(2005)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.829
, pp. 82-90
-
-
Dickinson, L.1
Robinson, L.2
Tjia, J.3
-
21
-
-
34147176581
-
The tablet formulation of lopinavir/ritonavir provides similar bioavailability to the soft-gelatin capsule formulation with less pharmacokinetic variability and diminished food effect
-
Klein CE, Chiu YL, Awni W, et al. The tablet formulation of lopinavir/ritonavir provides similar bioavailability to the soft-gelatin capsule formulation with less pharmacokinetic variability and diminished food effect. J Acquir Immune Defic Syndr 2007; 44:401-410.
-
(2007)
J Acquir Immune Defic Syndr
, vol.44
, pp. 401-410
-
-
Klein, C.E.1
Chiu, Y.L.2
Awni, W.3
-
22
-
-
42049114103
-
-
Jassen-Cilag Ltd: Prezista® (darunavir ethanolate) 300 mg film-coated tablets: summary of product characteristics. Wycomb, Buckinghamshire, UK: Jassen-Cilag Ltd; 2007.
-
Jassen-Cilag Ltd: Prezista® (darunavir ethanolate) 300 mg film-coated tablets: summary of product characteristics. Wycomb, Buckinghamshire, UK: Jassen-Cilag Ltd; 2007.
-
-
-
-
23
-
-
34548300159
-
Clinical pharmacokinetics of darunavir
-
Rittweger M, Arasteh K. Clinical pharmacokinetics of darunavir. Clin Pharmacokinet 2007; 46:739-756.
-
(2007)
Clin Pharmacokinet
, vol.46
, pp. 739-756
-
-
Rittweger, M.1
Arasteh, K.2
-
24
-
-
34250854707
-
Pharmacokinetics and antiretroviral response to darunavir/ritonavir and etravirine combination in patients with high-level viral resistance
-
Boffito M, Winston A, Jackson A, et al. Pharmacokinetics and antiretroviral response to darunavir/ritonavir and etravirine combination in patients with high-level viral resistance. AIDS 2007; 21:1449-1455.
-
(2007)
AIDS
, vol.21
, pp. 1449-1455
-
-
Boffito, M.1
Winston, A.2
Jackson, A.3
-
25
-
-
34547780413
-
Pharmacokinetics of darunavir/ritonavir and TMC125 alone and coadministered in HIV-negative volunteers
-
Scholler-Gyure M, Kakuda TN, Sekar V, et al. Pharmacokinetics of darunavir/ritonavir and TMC125 alone and coadministered in HIV-negative volunteers. Antivir Ther 2007; 12:789-796.
-
(2007)
Antivir Ther
, vol.12
, pp. 789-796
-
-
Scholler-Gyure, M.1
Kakuda, T.N.2
Sekar, V.3
-
26
-
-
33847672711
-
Pharmacokinetic interaction between darunavir boosted with ritonavir and omeprazole or ranitidine in human immunodeficiency virus-negative healthy volunteers
-
Sekar VJ, Lefebvre E, De Paepe E, et al. Pharmacokinetic interaction between darunavir boosted with ritonavir and omeprazole or ranitidine in human immunodeficiency virus-negative healthy volunteers. Antimicrob Agents Chemother 2007; 51:958-961.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 958-961
-
-
Sekar, V.J.1
Lefebvre, E.2
De Paepe, E.3
-
27
-
-
0027310686
-
Alpha 1-acid glycoprotein levels in AIDS patients before and after short-term treatment with zidovudine (ZDV)
-
Oie S, Jacobson MA, Abrams DI. Alpha 1-acid glycoprotein levels in AIDS patients before and after short-term treatment with zidovudine (ZDV). J Acquir Immune Defic Syndr 1993; 6:531-533.
-
(1993)
J Acquir Immune Defic Syndr
, vol.6
, pp. 531-533
-
-
Oie, S.1
Jacobson, M.A.2
Abrams, D.I.3
-
28
-
-
42049083199
-
-
th European AIDS Conference (EACS); 24-27 October 2007; Madrid, Spain. Paris, France: European AIDS Clinical Society; 2007.
-
th European AIDS Conference (EACS); 24-27 October 2007; Madrid, Spain. Paris, France: European AIDS Clinical Society; 2007.
-
-
-
-
29
-
-
42049088339
-
-
th Annual Meeting of the Population Approach Group in Europe (PAGE). 14-16 June 2006. Bruges, Belgium. June 2006 [Abstract 964] 2006. Paris, France: PAGE; 2006. http://www.page-meeting.org/? abstract=964 [Accessed 13 February 2008].
-
th Annual Meeting of the Population Approach Group in Europe (PAGE). 14-16 June 2006. Bruges, Belgium. June 2006 [Abstract 964] 2006. Paris, France: PAGE; 2006. http://www.page-meeting.org/? abstract=964 [Accessed 13 February 2008].
-
-
-
-
30
-
-
42049117654
-
-
GlaxoSmithKline UK: Telzir® (fosamprenavir calcium) 700 mg film-coated tablets: summary of product characteristics. Brentford, Middlesex, UK: Glaxo-SmithKline UK; 2007.
-
GlaxoSmithKline UK: Telzir® (fosamprenavir calcium) 700 mg film-coated tablets: summary of product characteristics. Brentford, Middlesex, UK: Glaxo-SmithKline UK; 2007.
-
-
-
-
31
-
-
42049106255
-
-
Kim YH, Hu C, Wire MB, et al. Steady-state amprenavir pharmacokinetics are similar between healthy and HIV-infected subjects following GW433908 ± ritonavir using population pharmacokinetic analysis [abstract 7.5]. In: Program and Abstracts of the 5th International Workshop on Clinical Pharmacology of HIV Therapy; 1-3 April 2004; Rome, Italy. Geneva, Switzerland: International AIDS Society; 2004.
-
Kim YH, Hu C, Wire MB, et al. Steady-state amprenavir pharmacokinetics are similar between healthy and HIV-infected subjects following GW433908 ± ritonavir using population pharmacokinetic analysis [abstract 7.5]. In: Program and Abstracts of the 5th International Workshop on Clinical Pharmacology of HIV Therapy; 1-3 April 2004; Rome, Italy. Geneva, Switzerland: International AIDS Society; 2004.
-
-
-
-
32
-
-
34548706470
-
Amprenavir and ritonavir plasma concentrations in HIV-infected patients treated with fosamprenavir/ritonavir with various degrees of liver impairment
-
Seminari E, De Bona A, Gentilini G, et al. Amprenavir and ritonavir plasma concentrations in HIV-infected patients treated with fosamprenavir/ritonavir with various degrees of liver impairment. J Antimicrob Chemother 2007; 60:831-836.
-
(2007)
J Antimicrob Chemother
, vol.60
, pp. 831-836
-
-
Seminari, E.1
De Bona, A.2
Gentilini, G.3
-
33
-
-
33344460707
-
Fosamprenavir: Clinical pharmacokinetics and drug interactions of the amprenavir prodrug
-
Wire MB, Shelton MJ, Studenberg S. Fosamprenavir: clinical pharmacokinetics and drug interactions of the amprenavir prodrug. Clin Pharmacokinet 2006; 45:137-168.
-
(2006)
Clin Pharmacokinet
, vol.45
, pp. 137-168
-
-
Wire, M.B.1
Shelton, M.J.2
Studenberg, S.3
-
34
-
-
20144365012
-
Combining fosamprenavir with lopinavir/ritonavir substantially reduces amprenavir and lopinavir exposure: ACTG protocol A5143 results
-
Kashuba AD, Tierney C, Downey GF, et al. Combining fosamprenavir with lopinavir/ritonavir substantially reduces amprenavir and lopinavir exposure: ACTG protocol A5143 results. AIDS 2005; 19:145-152.
-
(2005)
AIDS
, vol.19
, pp. 145-152
-
-
Kashuba, A.D.1
Tierney, C.2
Downey, G.F.3
-
35
-
-
34547617204
-
Fosamprenavir plus ritonavir increases plasma ketoconazole and ritonavir exposure, while amprenavir exposure remains unchanged
-
Wire MB, Ballow CH, Borland J, et al. Fosamprenavir plus ritonavir increases plasma ketoconazole and ritonavir exposure, while amprenavir exposure remains unchanged. Antimicrob Agents Chemother 2007; 51:2982-2984.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 2982-2984
-
-
Wire, M.B.1
Ballow, C.H.2
Borland, J.3
-
36
-
-
33846601305
-
Plasma amprenavir pharmacokinetics and tolerability following administration of 1,400 milligrams of fosamprenavir once daily in combination with either 100 or 200 milligrams of ritonavir in healthy volunteers
-
Ruane PJ, Luber AD, Wire MB, et al. Plasma amprenavir pharmacokinetics and tolerability following administration of 1,400 milligrams of fosamprenavir once daily in combination with either 100 or 200 milligrams of ritonavir in healthy volunteers. Antimicrob Agents Chemother 2007; 51:560-565.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 560-565
-
-
Ruane, P.J.1
Luber, A.D.2
Wire, M.B.3
-
37
-
-
33745448252
-
Coadministration of esomeprazole with fosamprenavir has no impact on steady-state plasma amprenavir pharmacokinetics
-
Shelton MJ, Ford SL, Borland J, et al. Coadministration of esomeprazole with fosamprenavir has no impact on steady-state plasma amprenavir pharmacokinetics. J Acquir Immune Defic Syndr 2006; 42:61-67.
-
(2006)
J Acquir Immune Defic Syndr
, vol.42
, pp. 61-67
-
-
Shelton, M.J.1
Ford, S.L.2
Borland, J.3
-
38
-
-
2142700048
-
Pharmacokinetics and safety of GW433908 and ritonavir, with and without efavirenz, in healthy volunteers
-
Wire MB, Ballow C, Preston SL, et al. Pharmacokinetics and safety of GW433908 and ritonavir, with and without efavirenz, in healthy volunteers. AIDS 2004; 18:897-907.
-
(2004)
AIDS
, vol.18
, pp. 897-907
-
-
Wire, M.B.1
Ballow, C.2
Preston, S.L.3
-
39
-
-
42049089195
-
-
Abbott Laboratories Limited: Kaletra® (lopinavir/ritonavir) 133.3/33.3 mg soft capsules: summary of product characteristics. Abbott Park, Illinois, USA: Abbott Laboratories Limited; 2007.
-
Abbott Laboratories Limited: Kaletra® (lopinavir/ritonavir) 133.3/33.3 mg soft capsules: summary of product characteristics. Abbott Park, Illinois, USA: Abbott Laboratories Limited; 2007.
-
-
-
-
40
-
-
42049107560
-
Kaletra® (lopinavir/ritonavir) 200/50 mg film-coated tablets: Summary of product characteristics
-
Abbott Laboratories Limited
-
Abbott Laboratories Limited: Kaletra® (lopinavir/ritonavir) 200/50 mg film-coated tablets: summary of product characteristics. Abbott Park, Illinois, USA: Abbott Laboratories Limited; 2007.
-
(2007)
Abbott Park, Illinois, USA: Abbott Laboratories Limited
-
-
-
41
-
-
33846156577
-
Lopinavir/ritonavir pharmacokinetics in HIV and hepatitis C virus co-infected patients without liver function impairment: Influence of liver fibrosis
-
Molto J, Valle M, Blanco A, et al. Lopinavir/ritonavir pharmacokinetics in HIV and hepatitis C virus co-infected patients without liver function impairment: influence of liver fibrosis. Clin Pharmacokinet 2007; 46:85-92.
-
(2007)
Clin Pharmacokinet
, vol.46
, pp. 85-92
-
-
Molto, J.1
Valle, M.2
Blanco, A.3
-
42
-
-
33746135180
-
Pharmacokinetics and tolerability of a combination of indinavir, lopinavir and ritonavir in multiply pretreated HIV-1 infected adults
-
von Hentig N, Muller A, Rottmann C, et al. Pharmacokinetics and tolerability of a combination of indinavir, lopinavir and ritonavir in multiply pretreated HIV-1 infected adults. Eur J Med Res 2006; 11:236-244.
-
(2006)
Eur J Med Res
, vol.11
, pp. 236-244
-
-
von Hentig, N.1
Muller, A.2
Rottmann, C.3
-
43
-
-
33748043297
-
Association of total bilirubin with indinavir and lopinavir plasma concentrations in HIV-infected patients receiving three different double-boosted dosing regimens
-
Dicenzo R, Luque A, Larppanichpoonphol P, et al. Association of total bilirubin with indinavir and lopinavir plasma concentrations in HIV-infected patients receiving three different double-boosted dosing regimens. J Antimicrob Chemother 2006; 58:393-400.
-
(2006)
J Antimicrob Chemother
, vol.58
, pp. 393-400
-
-
Dicenzo, R.1
Luque, A.2
Larppanichpoonphol, P.3
-
44
-
-
0035986072
-
Salvage treatment with lopinavir/ritonavir (Kaletra) in HIV-infected patients failing all current antiretroviral drug families
-
de Mendoza C, Martin-Carbonero L, Barreiro P, et al. Salvage treatment with lopinavir/ritonavir (Kaletra) in HIV-infected patients failing all current antiretroviral drug families. HIV Clin Trials 2002; 3:304-309.
-
(2002)
HIV Clin Trials
, vol.3
, pp. 304-309
-
-
de Mendoza, C.1
Martin-Carbonero, L.2
Barreiro, P.3
-
45
-
-
33846039806
-
Lopinavir/ritonavir reduces bupropion plasma concentrations in healthy subjects
-
Hogeland GW, Swindells S, McNabb JC, et al. Lopinavir/ritonavir reduces bupropion plasma concentrations in healthy subjects. Clin Pharmacol Ther 2007; 81:69-75.
-
(2007)
Clin Pharmacol Ther
, vol.81
, pp. 69-75
-
-
Hogeland, G.W.1
Swindells, S.2
McNabb, J.C.3
-
46
-
-
33845416796
-
Interactions between buprenorphine and antiretrovirals. II. The protease inhibitors nelfinavir, lopinavir/ritonavir, and ritonavir
-
McCance-Katz EF, Moody DE, Smith PF, et al. Interactions between buprenorphine and antiretrovirals. II. The protease inhibitors nelfinavir, lopinavir/ritonavir, and ritonavir. Clin Infect Dis 2006; 43 (suppl 4):S235-S246.
-
(2006)
Clin Infect Dis
, vol.43
, Issue.SUPPL. 4
-
-
McCance-Katz, E.F.1
Moody, D.E.2
Smith, P.F.3
-
47
-
-
33750570685
-
Pharmacokinetics and safety of tenofovir disoproxil fumarate on coadministration with lopinavir/ritonavir
-
Kearney BP, Mathias A, Mittan A, et al. Pharmacokinetics and safety of tenofovir disoproxil fumarate on coadministration with lopinavir/ritonavir. J Acquir Immune Defic Syndr 2006; 43:278-283.
-
(2006)
J Acquir Immune Defic Syndr
, vol.43
, pp. 278-283
-
-
Kearney, B.P.1
Mathias, A.2
Mittan, A.3
-
48
-
-
3342927541
-
Coadministration of lopinavir/ritonavir and phenytoin results in two-way drug interaction through cytochrome P-450 induction
-
Lim ML, Min SS, Eron JJ, et al. Coadministration of lopinavir/ritonavir and phenytoin results in two-way drug interaction through cytochrome P-450 induction. J Acquir Immune Defic Syndr 2004; 36:1034-1040.
-
(2004)
J Acquir Immune Defic Syndr
, vol.36
, pp. 1034-1040
-
-
Lim, M.L.1
Min, S.S.2
Eron, J.J.3
-
49
-
-
2142827107
-
Pharmacokinetics of adjusted-dose lopinavir-ritonavir combined with rifampin in healthy volunteers
-
la Porte CJ, Colbers EP, Bertz R, et al. Pharmacokinetics of adjusted-dose lopinavir-ritonavir combined with rifampin in healthy volunteers. Antimicrob Agents Chemother 2004; 48:1553-1560.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 1553-1560
-
-
la Porte, C.J.1
Colbers, E.P.2
Bertz, R.3
-
50
-
-
42049124127
-
-
Roche Pharmaceuticals: Invirase® (saquinavir mesylate) capsules and tablets: US prescribing information. Nutley, New Jersey, USA: Roche Pharmaceuticals; 2007.
-
Roche Pharmaceuticals: Invirase® (saquinavir mesylate) capsules and tablets: US prescribing information. Nutley, New Jersey, USA: Roche Pharmaceuticals; 2007.
-
-
-
-
51
-
-
42049123920
-
-
Dickinson L, Back D, Winston A, et al. Intra-patient variability and comparison of saquinavir/ritonavir Ctrough concentrations between HIV-infected individuals and healthy volunteers administered saquinavir mesylate 500 mg film-coated tablets (1000/100 mg twice daily) [abstract 60]. In: Program and Abstracts of the 7th International Workshop on Clinical Pharmacology of HIV Therapy; 20-22 April 2006; Lisbon, Portugal. Geneva, Switzerland: International AIDS Society; 2006.
-
Dickinson L, Back D, Winston A, et al. Intra-patient variability and comparison of saquinavir/ritonavir Ctrough concentrations between HIV-infected individuals and healthy volunteers administered saquinavir mesylate 500 mg film-coated tablets (1000/100 mg twice daily) [abstract 60]. In: Program and Abstracts of the 7th International Workshop on Clinical Pharmacology of HIV Therapy; 20-22 April 2006; Lisbon, Portugal. Geneva, Switzerland: International AIDS Society; 2006.
-
-
-
-
52
-
-
0035041368
-
The interaction of saquinavir (soft gelatin capsule) with ketoconazole, erythromycin and rifampicin: Comparison of the effect in healthy volunteers and in HIV-infected patients
-
Grub S, Bryson H, Goggin T, et al. The interaction of saquinavir (soft gelatin capsule) with ketoconazole, erythromycin and rifampicin: comparison of the effect in healthy volunteers and in HIV-infected patients. Eur J Clin Pharmacol 2001; 57:115-121.
-
(2001)
Eur J Clin Pharmacol
, vol.57
, pp. 115-121
-
-
Grub, S.1
Bryson, H.2
Goggin, T.3
-
53
-
-
42049113236
-
-
••].
-
••].
-
-
-
-
54
-
-
33745456982
-
-
max were 82%, 106% and 75%, respectively).
-
max were 82%, 106% and 75%, respectively).
-
-
-
-
55
-
-
35948968734
-
Association of saquinavir plasma concentrations with side effects but not with antiretroviral outcome in patients infected with protease inhibitor-susceptible human immunodeficiency virus type 1
-
Lotsch J, Harder S, Sturmer M, et al. Association of saquinavir plasma concentrations with side effects but not with antiretroviral outcome in patients infected with protease inhibitor-susceptible human immunodeficiency virus type 1. Antimicrob Agents Chemother 2007; 51:3264-3272.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 3264-3272
-
-
Lotsch, J.1
Harder, S.2
Sturmer, M.3
-
56
-
-
34248189706
-
Saquinavir, nelfinavir and M8 pharmacokinetics following combined saquinavir, ritonavir and nelfinavir administration
-
Stocker H, Herzmann C, Breske A, et al. Saquinavir, nelfinavir and M8 pharmacokinetics following combined saquinavir, ritonavir and nelfinavir administration. J Antimicrob Chemother 2007; 59:560-564.
-
(2007)
J Antimicrob Chemother
, vol.59
, pp. 560-564
-
-
Stocker, H.1
Herzmann, C.2
Breske, A.3
-
57
-
-
20244374969
-
Boosted saquinavir hard gel formulation exposure in HIV-infected subjects: Ritonavir 100 mg once daily versus twice daily
-
Boffito M, Maitland D, Dickinson L, et al. Boosted saquinavir hard gel formulation exposure in HIV-infected subjects: ritonavir 100 mg once daily versus twice daily. J Antimicrob Chemother 2005; 55:542-545.
-
(2005)
J Antimicrob Chemother
, vol.55
, pp. 542-545
-
-
Boffito, M.1
Maitland, D.2
Dickinson, L.3
-
58
-
-
19944377562
-
Pharmacokinetics of saquinavir hard gel/ritonavir (1000/100 mg twice daily) when administered with tenofovir diproxil fumarate in HIV-1-infected subjects
-
Boffito M, Back D, Stainsby-Tron M, et al. Pharmacokinetics of saquinavir hard gel/ritonavir (1000/100 mg twice daily) when administered with tenofovir diproxil fumarate in HIV-1-infected subjects. Br J Clin Pharmacol 2005; 59:38-42.
-
(2005)
Br J Clin Pharmacol
, vol.59
, pp. 38-42
-
-
Boffito, M.1
Back, D.2
Stainsby-Tron, M.3
-
59
-
-
33846445233
-
Pharmacokinetics of saquinavir with atazanavir or low-dose ritonavir administered once daily (ASPIRE I) or twice daily (ASPIRE II) in seronegative volunteers
-
King JR, Kakuda TN, Paul S, et al. Pharmacokinetics of saquinavir with atazanavir or low-dose ritonavir administered once daily (ASPIRE I) or twice daily (ASPIRE II) in seronegative volunteers. J Clin Pharmacol 2007; 47:201-208.
-
(2007)
J Clin Pharmacol
, vol.47
, pp. 201-208
-
-
King, J.R.1
Kakuda, T.N.2
Paul, S.3
-
60
-
-
33645795947
-
Pharmacokinetics of tenofovir disoproxil fumarate and ritonavir-boosted saquinavir mesylate administered alone or in combination at steady state
-
Chittick GE, Zong J, Blum MR, et al. Pharmacokinetics of tenofovir disoproxil fumarate and ritonavir-boosted saquinavir mesylate administered alone or in combination at steady state. Antimicrob Agents Chemother 2006; 50:1304-1310.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, pp. 1304-1310
-
-
Chittick, G.E.1
Zong, J.2
Blum, M.R.3
-
61
-
-
0037648770
-
Pharmacokinetic and tolerability profile of twice-daily saquinavir hard gelatin capsules and saquinavir soft gelatin capsules boosted with ritonavir in healthy volunteers
-
Kurowski M, Sternfeld T, Sawyer A, et al. Pharmacokinetic and tolerability profile of twice-daily saquinavir hard gelatin capsules and saquinavir soft gelatin capsules boosted with ritonavir in healthy volunteers. HIV Med 2003; 4:94-100.
-
(2003)
HIV Med
, vol.4
, pp. 94-100
-
-
Kurowski, M.1
Sternfeld, T.2
Sawyer, A.3
-
63
-
-
42049084674
-
-
Boehringer Ingelheim Pharmaceuticals: Aptivus® (tipranavir) capsules: US prescribing information. Ridgefield, Connecticut, USA: Boehringer Ingelheim Limited; 2007.
-
Boehringer Ingelheim Pharmaceuticals: Aptivus® (tipranavir) capsules: US prescribing information. Ridgefield, Connecticut, USA: Boehringer Ingelheim Limited; 2007.
-
-
-
-
64
-
-
42049100385
-
-
th Conference on Retroviruses and Opportunistic Infections (CROI); 22-25 February 2005; Boston, Massachusetts, USA. Alexandria, Virginia, USA: CROI; 2005. http://www.aegis.com/conferences/croi/2005/654.html [Accessed 13 February 2008].
-
th Conference on Retroviruses and Opportunistic Infections (CROI); 22-25 February 2005; Boston, Massachusetts, USA. Alexandria, Virginia, USA: CROI; 2005. http://www.aegis.com/conferences/croi/2005/654.html [Accessed 13 February 2008].
-
-
-
-
65
-
-
42049110390
-
-
Sabo JP, Yong CL, MacGregor TR, et al. Nonlinear mixed effects modeling of the steady-state pharmacokinetics of tipranavir for adult healthy volunteers and HIV+ patients receiving TPV 500 mg bid coadministered with RTV 100 mg or 200 mg bid [abstract 7]. In: Program and Abstracts of the 8th International Workshop on Clinical Pharmacology of HIV Therapy; 16-18 April 2007; Budapest, Hungary. Geneva, Switzerland: International AIDS Society; 2007.
-
Sabo JP, Yong CL, MacGregor TR, et al. Nonlinear mixed effects modeling of the steady-state pharmacokinetics of tipranavir for adult healthy volunteers and HIV+ patients receiving TPV 500 mg bid coadministered with RTV 100 mg or 200 mg bid [abstract 7]. In: Program and Abstracts of the 8th International Workshop on Clinical Pharmacology of HIV Therapy; 16-18 April 2007; Budapest, Hungary. Geneva, Switzerland: International AIDS Society; 2007.
-
-
-
-
66
-
-
42049113896
-
-
Bonora S, D'Avolio A, Gonzalez de Requena D, et al. Intracellular accumulation of tipranavir/ritonavir in the clinical setting [abstract 48]. In: Program and Abstracts of the 8th International Workshop on Clinical Pharmacology of HIV Therapy; 16-18 April 2007; Budapest, Hungary. Geneva, Switzerland: International AIDS Society; 2007.
-
Bonora S, D'Avolio A, Gonzalez de Requena D, et al. Intracellular accumulation of tipranavir/ritonavir in the clinical setting [abstract 48]. In: Program and Abstracts of the 8th International Workshop on Clinical Pharmacology of HIV Therapy; 16-18 April 2007; Budapest, Hungary. Geneva, Switzerland: International AIDS Society; 2007.
-
-
-
-
67
-
-
33748893949
-
Unexpected drug-drug interaction between tipranavir/ritonavir and enfuvirtide
-
Gonzalez de Requena D, Calcagno A, et al. Unexpected drug-drug interaction between tipranavir/ritonavir and enfuvirtide. AIDS 2006; 20:1977-1979.
-
(2006)
AIDS
, vol.20
, pp. 1977-1979
-
-
Gonzalez de Requena, D.1
Calcagno, A.2
-
68
-
-
42049092176
-
-
Curran A, Lopez R, Pou L, et al. Pharmacokinetic evaluation of potential interaction between tipranavir and enfuvirtide [abstract 53]. In: Program and Abstracts of the 7th International Workshop on Clinical Pharmacology of HIV Therapy; 20-22 April 2006; Lisbon, Portugal. Geneva, Switzerland: International AIDS Society; 2006.
-
Curran A, Lopez R, Pou L, et al. Pharmacokinetic evaluation of potential interaction between tipranavir and enfuvirtide [abstract 53]. In: Program and Abstracts of the 7th International Workshop on Clinical Pharmacology of HIV Therapy; 20-22 April 2006; Lisbon, Portugal. Geneva, Switzerland: International AIDS Society; 2006.
-
-
-
-
69
-
-
34447275664
-
Steady-state disposition of the nonpeptidic protease inhibitor tipranavir when coadministered with ritonavir
-
Chen L, Sabo JP, Philip E, et al. Steady-state disposition of the nonpeptidic protease inhibitor tipranavir when coadministered with ritonavir. Antimicrob Agents Chemother 2007; 51:2436-2444.
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 2436-2444
-
-
Chen, L.1
Sabo, J.P.2
Philip, E.3
-
70
-
-
42049113681
-
-
la Porte CJ, Cameron DW, Sabo JP, et al. The effect of omeprazole, food and formulation on the pharmacokinetics of tipranavir coadministered with ritonavir [abstract 59]. In: Program and Abstracts of the 8th International Workshop on Clinical Pharmacology of HIV Therapy; 16-18 April 2007; Budapest, Hungary. Geneva, Switzerland: International AIDS Society; 2007.
-
la Porte CJ, Cameron DW, Sabo JP, et al. The effect of omeprazole, food and formulation on the pharmacokinetics of tipranavir coadministered with ritonavir [abstract 59]. In: Program and Abstracts of the 8th International Workshop on Clinical Pharmacology of HIV Therapy; 16-18 April 2007; Budapest, Hungary. Geneva, Switzerland: International AIDS Society; 2007.
-
-
-
-
71
-
-
13844296701
-
Pharmacokinetic characterization of different dose combinations of coadministered tipranavir and ritonavir in healthy volunteers
-
MacGregor TR, Sabo JP, Norris SH, et al. Pharmacokinetic characterization of different dose combinations of coadministered tipranavir and ritonavir in healthy volunteers. HIV Clin Trials 2004; 5:371-382.
-
(2004)
HIV Clin Trials
, vol.5
, pp. 371-382
-
-
MacGregor, T.R.1
Sabo, J.P.2
Norris, S.H.3
|