A novel time-controlled release system based on drug-resin complexes and elementary osmotic pump

Chemical and Pharmaceutical Bulletin

Volumn 56, Issue 4, 2008, Pages 457-463

  Wang, Chao ^a   Chen, Fei ^a   Heng, Paul Wan Sia ^b   Li, Ji Zhong ^a   Li, Xiang ^a   Ye, Guan Hao ^a   Nie, Shu Fang ^a   Pan, Wei San ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Drug release mechanism; Drug resin complexes; Osmotic pump tablet; Propranolol hydrochloride; Time controlled delivery

Indexed keywords

BISOPROLOL FUMARATE; CELLULOSE ACETATE; ELECTROLYTE; MACROGOL; MACROGOL 4000; POLACRILIN; POVIDONE; PROPRANOLOL; RESIN; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ARTICLE; CHRONOTHERAPY; COMPLEX FORMATION; CONDUCTANCE; DOG; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; ION EXCHANGE; NONHUMAN; OSMOTIC PRESSURE; OSMOTIC PUMP; TABLET; TIMED DRUG RELEASE;

ADRENERGIC BETA-ANTAGONISTS; ALGORITHMS; ANIMALS; AREA UNDER CURVE; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, ION EXCHANGE; DELAYED-ACTION PREPARATIONS; DOGS; ELECTRIC CONDUCTIVITY; OSMOSIS; PHARMACEUTICAL PREPARATIONS; POLYETHYLENE GLYCOLS; PROPRANOLOL; RESINS, SYNTHETIC; SODIUM CHLORIDE; SOLUBILITY; SPECTROPHOTOMETRY, ULTRAVIOLET; TABLETS;

EID: 42049104093     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.56.457     Document Type: Article

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