Protective effects of elevated endogenous surfactant pools to injurious mechanical ventilation

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 294, Issue 4, 2008, Pages

  Yamashita, Cory ^a   Forbes, Amy ^a   Tessolini, Jenna M ^a   Yao, Li Juan ^a   Lewis, James F ^a   Veldhuizen, Ruud A W ^a,b  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b LAWSON HEALTH RESEARCH INSTITUTE   (Canada)

Author keywords

Alveolar macrophages; Inflammatory mediators

Indexed keywords

CLODRONIC ACID; LIPOSOME; SURFACTANT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; CONTROLLED STUDY; LUNG ALVEOLUS MACROPHAGE; LUNG COMPLIANCE; LUNG INJURY; MALE; NONHUMAN; OXYGENATION; PRIORITY JOURNAL; RAT;

ANIMALS; CLODRONIC ACID; LIPOSOMES; LUNG DISEASES; MACROPHAGES, ALVEOLAR; MALE; PULMONARY SURFACTANTS; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATION, ARTIFICIAL; TRACHEA;

EID: 42049102173     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00389.2007     Document Type: Article

References (36)

1. Benoit A, Huang Y, Proctor J, Rowden G, Anderson R. Effects of alveolar macrophage depletion on liposomal vaccine protection against respiratory syncytial virus (RSV). Clin Exp Immunol 145: 147-154, 2006.
2. Berg JT, White JE, Tsan MF. Response of alveolar macrophage-depleted rats to hyperoxia. Exp Lung Res 21: 175-185, 1995.
3. Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37: 911-917, 1959.
4. Brower RG, Matthay MA, Morris A, Schoenfeld D, Thompson BT, Wheeler A. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med 342: 1301-1308, 2000.
5. Cockshutt AM, Weitz J, Possmayer F. Pulmonary surfactant- associated protein A enhances the surface activity of lipid extract surfactant and reverses inhibition by blood proteins in vitro. Biochemistry 29: 8424-8429, 1990.
6. Dos Santos CC, Slutsky AS. The contribution of biophysical lung injury to the development of biotrauma. Annu Rev Physiol 68: 585-618, 2006.
7. Dreyfuss D, Saumon G. Ventilator-induced lung injury: lessons from experimental studies. Am J Respir Crit Care Med 157: 294-323, 1998.
8. Duck-Chong CG. A rapid sensitive method for determining phospholipid phosphorus involving digestion with magnesium nitrate. Lipids 14: 492-497, 1979.
9. Eyal FG, Hamm CR, Parker JC. Reduction in alveolar macrophages attenuates acute ventilator induced lung injury in rats. Intensive Care Med 33: 1212-1218, 2007.
10. Forbes A, Pickell M, Foroughian M, Yao LJ, Lewis J, Veldhuizen R. Alveolar macrophage depletion is associated with increased surfactant pool sizes in adult rats. J Appl Physiol 103: 637-645, 2007.
11. Frank JA, Wray CM, McAuley DF, Schwendener R, Matthay MA. Alveolar macrophages contribute to alveolar barrier dysfunction in ventilator-induced lung injury. Am J Physiol Lung Cell Mol Physiol 291: L1191-L1198, 2006.
12. Gilliard N, Pappert D, Spragg RG. Fractal analysis of surfactant deposition in rabbit lungs. J Appl Physiol 78: 862-866, 1995.
13. Gilliard N, Richman PM, Merritt TA, Spragg RG. Effect of volume and dose on the pulmonary distribution of exogenous surfactant administered to normal rabbits or to rabbits with oleic acid lung injury. Am Rev Respir Dis 141: 743-747, 1990.
14. Goerke J. Pulmonary surfactant: functions and molecular composition. Biochim Biophys Acta 1408: 79-89, 1998.
15. Gross NJ, Kellam M, Young J, Krishnasamy S, Dhand R. Separation of alveolar surfactant into subtypes. A comparison of methods. Am J Respir Crit Care Med 162: 617-622, 2000.
16. Ikegami M, Ueda T, Hull W, Whitsett JA, Mulligan RC, Dranoff G, Jobe AH. Surfactant metabolism in transgenic mice after granulocyte macrophage-colony stimulating factor ablation. Am J Physiol Lung Cell Mol Physiol 270: L650-L658, 1996.
17. Leemans JC, Juffermans NP, Florquin S, Van Rooijen N, Vervoordeldonk MJ, Verbon A, van Deventer SJ, van der Poll T. Depletion of alveolar macrophages exerts protective effects in pulmonary tuberculosis in mice. J Immunol 166: 4604-4611, 2001.
18. Lewis JF, Veldhuizen R. The role of exogenous surfactant in the treatment of acute lung injury. Annu Rev Physiol 65: 613-642, 2003.
19. Malloy JL, Veldhuizen RA, Lewis JF. Effects of ventilation on the surfactant system in sepsis-induced lung injury. J Appl Physiol 88: 401-408, 2000.
20. McCormack FX, Whitsett JA. The pulmonary collectins, SP-A and SP-D, orchestrate innate immunity in the lung. J Clin Invest 109: 707-712, 2002.
21. Putz G, Goerke J, Clements JA. Surface activity of rabbit pulmonary surfactant subfractions at different concentrations in a captive bubble. J Appl Physiol 77: 597-605, 1994.
22. Ranieri VM, Giunta F, Suter PM, Slutsky AS. Mechanical ventilation as a mediator of multisystem organ failure in acute respiratory distress syndrome [letter]. JAMA 284: 43-44, 2000.
23. Schurch S, Bachofen H, Goerke J, Possmayer F. A captive bubble method reproduces the in situ behavior of lung surfactant monolayers. J Appl Physiol 67: 2389-2396, 1989.
24. Slutsky AS, Tremblay LN. Multi system organ failure: is mechanical ventilation a contributing factor? Am J Respir Crit Care Med 157: 1721-1725, 1998.
25. Spragg RG, Lewis JF, Wurst W, Hafner D, Baughman RP, Wewers MD, Marsh JJ. Treatment of acute respiratory distress syndrome with recombinant surfactant protein C surfactant. Am J Respir Crit Care Med 167: 1562-1566, 2003.
26. Van Rooijen N, Sanders A. Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications. J Immunol Methods 174: 83-93, 1994.
27. Vazquez de Anda GF, Lachmann RA, Gommers D, Verbrugge SJ, Haitsma J, Lachmann B. Treatment of ventilation-induced lung injury with exogenous surfactant. Intensive Care Med 27: 559-565, 2001.
28. Veldhuizen RA, Welk B, Harbottle R, Hearn S, Nag K, Petersen N, Possmayer F. Mechanical ventilation of isolated rat lungs changes the structure and biophysical properties of surfactant. J Appl Physiol 92: 1169-1175, 2002.
29. Veldhuizen RAW, Ito Y, Marcou J, Yao LJ, McCaig L, Lewis JF. Effects of lung injury on pulmonary surfactant aggregate conversion in vivo and in vitro. Am J Physiol Lung Cell Mol Physiol 272: L872-L878, 1997.
30. Veldhuizen RAW, Tremblay LN, Govindarajan A, Rozendaal BAWM, Haagsman HP, Slutsky AS. Pulmonary surfactant is altered during mechanical ventilation of isolated rat lung. Crit Care Med 28: 2545-2551, 2000.
31. Verbrugge SJ, Bohm SH, Gommers D, Zimmermann LJ, Lachmann B. Surfactant impairment after mechanical ventilation with large alveolar surface area changes and effects of positive end-expiratory pressure. Br J Anaesth 80: 360-364, 1998.
32. Verbrugge SJ, Lachmann B. Mechanisms of ventilation-induced lung injury: physiological rationale to prevent it. Monaldi Arch Chest Dis 54: 22-37, 1999.
33. Verbrugge SJ, Vazquez dA, Gommers D, Neggers SJ, Sorm V, Bohm SH, Lachmann B. Exogenous surfactant preserves lung function and reduces alveolar evans blue dye influx in a rat model of ventilation-induced lung injury. Anesthesiology 89: 467-474, 1998.
34. Welk B, Malloy JL, Joseph M, Yao LJ, Veldhuizen AW. Surfactant treatment for ventilation-induced lung injury in rats: effects on lung compliance and cytokines. Exp Lung Res 27: 505-520, 2001.
35. Wright JR, Clements JA. Metabolism and turnover of lung surfactant. Am Rev Respir Dis 136: 426-444, 1987.
36. Yamada T, Ikegami M, Jobe AH. Effects of surfactant subfractions on preterm rabbit lung function. Pediatr Res 27: 592-598, 1990.