Evaluation of a 2-pyridone, KRQ-10018, against Mycobacterium tuberculosis in vitro and in vivo

Antimicrobial Agents and Chemotherapy

Volumn 52, Issue 4, 2008, Pages 1513-1515

  Lenaerts, Anne J ^a   Bitting, Casey ^a   Woolhiser, Lisa ^a   Gruppo, Veronica ^a   Marietta, Karen S ^a   Johnson, Christine M ^a   Orme, Ian M ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 PYRIDONE DERIVATIVE; ISONIAZID; KRQ 10018; MOXIFLOXACIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; IN VITRO STUDY; IN VIVO STUDY; LUNG TUBERCULOSIS; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; SINGLE DRUG DOSE; STRUCTURE ANALYSIS; THERAPY EFFECT; TREATMENT OUTCOME; TREATMENT RESPONSE;

ANIMALS; ANTITUBERCULAR AGENTS; BIOLOGICAL AVAILABILITY; INTERFERON TYPE II; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; PYRIDONES; QUINOLONES; TREATMENT OUTCOME; TUBERCULOSIS, PULMONARY;

EID: 42049093588     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.00897-07     Document Type: Article

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