The contents of the neuro-excitatory amino acid β-ODAP (β-N-oxalyl-l-α,β-diaminopropionic acid), and other free and protein amino acids in the seeds of different genotypes of grass pea (Lathyrus sativus L.)

Food Chemistry

Volumn 110, Issue 2, 2008, Pages 422-427

  Fikre, Asnake ^a,b   Korbu, Lijalem ^a,b   Kuo, Yu Haey ^a   Lambein, Fernand ^a  

^a GHENT UNIVERSITY   (Belgium)

^b ETHIOPIAN INSTITUTE OF AGRICULTURAL RESEARCH   (Ethiopia)

Author keywords

Drought tolerance; Food legume; Free and protein amino acids; Homoarginine; Methionine; Neurolathyrism

Indexed keywords

3 OXALYLAMINOALANINE; AMINO ACID DERIVATIVE; ARGININE; ASPARTIC ACID; EXCITATORY AMINO ACID; GLUTAMIC ACID; HOMOARGININE; LEUCINE; METHIONINE; PHENYL ISOTHIOCYANATE; PROLINE; PROTEIN; SULFUR AMINO ACID;

AMINO ACID COMPOSITION; ARTICLE; DERIVATIZATION; GENOTYPE; GRASS PEA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LEGUME; LENTIL; NONHUMAN; PLANT SEED; QUANTITATIVE ANALYSIS; SOYBEAN;

GLYCINE MAX; LATHYRUS SATIVUS; LENS CULINARIS; PISUM SATIVUM;

EID: 41949120491     PISSN: 03088146     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.foodchem.2008.02.019     Document Type: Article

References (30)

1. Campbell, C. G. (1997). Grass pea. Lathyrus sativus L. Promoting the conservation and use of underutilized and neglected crops. Nr 18. Institute of Plant Genetics and Crop Plant Research, Gatersleben, Germany/International Plant Genetic Resources Institute, Rome, Italy. p. 92.
2. Dahiya B.S., and Jeswani L.M. Genotype & environment interactions for neurotoxic principle (BOAA) in grass pea. Indian Journal of Agricultural Sciences 45 9 (1975) 437-439
3. Davies A.J., Nunn P.B., O'Brien P., Pettit L.D., and Wang G.F. Facile isolation from Lathyrus sativus seed of the neurotoxin β-N-oxalyl-l-α,β-diaminopropionic acid as the copper complex and studies of the coordination chemistry of copper and zinc with the amino acid in aqueous solution. Journal of Inorganic Biochemistry 39 (1990) 209-216
4. Debre Zeit Annual Report. (2003). Debre Zeit Agricultural Research Center, Debre Zeit, Ethiopia. pp. 59-61.
5. Gatta C.D., Polignano G.B., and Bisignano V. Variation for protein content and seed weight in grass pea (Lathyrus spp.) germplasm. PGR Newsletter. FAO-Biodiversity issue 132 (2002) 30-34
6. Getahun H., Lambein F., Vanhoorne M., and Van der Stuyft P. Food-aid cereals to reduce neurolathyrism related to grass-pea preparations during famine. Lancet 362 (2003) 1808-1810
7. Hanbury C.D., Siddique K.H.M., Galwey N.W., and Cocks P.S. Genotype-environment interaction for seed yield and ODAP concentration of Lathyrus sativus L. and L. cicera L. in Mediterranean type environments. Euphytica 11 (2000) 45-60
8. Haque, R. (1997). A study on the effect of nutritional and agro-ecological factors on the accumulation of neurotoxin β-N-oxalyl-l-α,β-diaminopropionic acid (ODAP) and other amino acids in Lathyrus sativus (Khesari) aimed at repressing its toxin synthesis. PhD dissertation, Bangladesh Agricultural University, Mymensingh.
9. Jiao C.-J., Xu Q.-L., Wang C.-Y., Li F.-M., Li Z.-X., and Wang Y.-F. Accumulation pattern of toxin β-ODAP during lifespan and effect of nutrient elements on β-ODAP content in Lathyrus sativus seedlings. Journal of Agricultural Science 144 (2006) 369-375
10. Jyothi P., and Rao S.L.N. Sustained nitric oxide generation with l-homoarginine. Research Communications in Biochemistry and Cell and Molecular Biology 3 (1999) 223-232
11. Kebede N., Haque R., Kuo Y.-H., and Lambein F. Influence of nutrient supply on the toxicity of Lathyrus sativus. Acta Botanica Neerlandica 43 (1994) 295
12. Kuo Y.-H., Bau H.M., Quemener B., Khan J.K., and Lambein F. Solid state fermentation of Lathyrus seeds using Aspergillus oryzae and Rhizopus oligosporus sp. T3 to eliminate the neurotoxin β-ODAP without loss of nutritional value. Journal of the Science of Food and Agriculture 69 (1995) 81-89
13. Kuo Y.-H., Bau H.-M., Rozan P., Chowdhury B., and Lambein F. Reduction efficiency of the neurotoxin β-ODAP in low-toxin varieties of Lathyrus sativus seeds by solid state fermentation with Aspergillus oryzae and Rhizopus microsporus var Chinensis. Journal of the Science of Food and Agriculture 80 (2000) 2209-2215
14. Kuo Y.-H., Ikegami F., and Lambein F. Metabolic routes of β-(isoxazolin-5-on-2-yl)-l-alanine (BIA), the precursor of the neurotoxin ODAP (β-N-oxalyl-l-α,β-diaminopropionic acid), in different legume seedlings. Phytochemistry 49 (1998) 43-48
15. Kuo Y.-H., Ikegami F., and Lambein F. Neuroactive and other free amino acids in seed and young plants of Panax ginseng. Phytochemistry 62 (2003) 1087-1091
16. Kuo Y.-H., Rozan P., Lambein F., Frias J., and Vidal-Valverde C. Effects of different germination conditions on the content of free protein and non-protein amino acids of commercial legumes. Food Chemistry 86 4 (2004) 537-545
17. Kusama-Eguchi K., Suda A., Ikegami F., Kusama T., Ogawa Y., and Watanabe K. Neurotoxicity and pharmacology of Lathyrus sativus extracts of high- and low-toxicity strains. Journal of Natural Medicines 60 (2006) 107-112
18. Lambein F., Kuo Y.-H., Kusama-Eguchi K., and Ikegami F. 3-N-Oxalyl-l-2,3-diaminopropanoic acid, a multifunctional plant metabolite of toxic reputation. Arkivoc ix (2007) 45-52
19. Leakey C. Khesari Dhal - The poisonous pea. Appropriate Technology 6 (1979) 15-16
20. Monsoor M.A., and Yusuf H.K.M. In vitro protein digestibility of Lathyrus pea (Lathyrus sativus), lentil (Lens culinaris), and chickpea (Cicer arietinum). International Journal of Food Science and Technology 37 (2002) 97-99
21. Nunn P.B., Lyddiard J.R.A., Perera C.K.P.W., and Bell E.A. Grass pea-induced plasma methionine deficiency effects on motorneurons in neurolathyrism. Journal of Food, Agriculture and Environment 3 2 (2005) 347
22. Nunn P.B., Perera C.K.P.W., Bell E.A., and Lambein F. Appearance of the neurotoxin β-N-oxalyl-l-α,β-diaminopropionic acid (β-ODAP) and of homoarginine in systemic blood and urine following the consumption of cooked Lathyrus sativus by human volunteers. Archives Internationales de Physiologie et de Biochimie 102 (1994) B89
23. Ramanujam K.L., Sethi K.L., and Rao S.L.N. Stability of neurotoxin content in Khesari. Indian Journal of Genetics and Plant Breed 40 1 (1980) 300-304
24. Rozan P., Kuo Y.-H., and Lambein F. Amino acids in seeds and seedlings of the genus Lens. Phytochemistry 58 (2001) 281-289
25. Shamim M.Z., Hossain M.S., Islam K., Yusuf H.K.M., and Lambein F. Mechanism of ODAP toxicity in one-day-old chicks. Dhaka Univ. Journal of Biological Sciences 11 (2002) 1-7
26. Urga K., Fufa H., Biratu E., and Hussain A. Evaluation of Lathyrus sativus cultivated in Ethiopia for proximate composition, minerals, β-ODAP and anti-nutritional components. African Journal of Food, Agriculture, Nutrition and Development 5 1 (2005) 1-15
27. Wang X., Warkentin T.D., Briggs C.J., Oomah B.D., Campbell C.G., and Woods S. Total phenolics and condensed tannins in field pea (Pisum sativum L.) and grass pea (Lathyrus sativus L.). Euphytica 101 1 (1998) 97-102
28. Wang X., Warkentin T.D., Briggs C.J., Oomah B.D., Campbell C.G., and Woods S. Trypsin inhibitor activity in field pea (Pisum sativum L.) and grass pea (Lathyrus sativus L.). Journal of Agricultural and Food Chemistry 46 7 (1998) 2620-2623
29. Wuletaw T. Stability of grass pea (Lathyrus sativus L.) varieties for ODAP content and grain yield in Ethiopia. Lathyrus Lathyrism Newsletter 3 (2003) 32-34. http://www.go.to/lathyrus
30. Xie G.-X., Qiu Y.-P., Qiu M.-F., Gao X.-F., Liu Y.-M., and Jia W. Analysis of dencichine in Panax notoginseng by gas chromatography-mass spectrometry with ethyl chloroformate derivatization. Journal of Pharmaceutical and Biomedical Analysis 43 (2007) 920-925