Application of micellar electrokinetic capillary chromatography for evaluation of inhibitory effects on cytochrome P450 reaction

Journal of Chromatography A

Volumn 1189, Issue 1-2, 2008, Pages 274-277

  Konečný, Jiří ^a   Mičíková, Ivana ^a   Řemínek, Roman ^a   Glatz, Zdeněk ^a  

^a MASARYK UNIVERSITY   (Czech Republic)

Author keywords

CYP2C9; Cytochrome P450; Diclofenac; Drug metabolism; Ketoconazole; MEKC; Sulfaphenazole

Indexed keywords

CAPILLARY ELECTROPHORESIS; DATA REDUCTION; LIVER; METABOLISM; PROTEINS;

CYTOCHROME P450; DICLOFENAC; DRUG METABOLISM; KETOCONAZOLE; SULFAPHENAZOLE;

CHROMATOGRAPHIC ANALYSIS;

CYTOCHROME P450; DICLOFENAC; KETOCONAZOLE; SULFAPHENAZOLE;

ARTICLE; CHEMICAL REACTION; DRUG INHIBITION; HUMAN; HUMAN TISSUE; IC 50; LIVER; MICELLAR ELECTROKINETIC CHROMATOGRAPHY; MOLECULAR MODEL; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL;

ARYL HYDROCARBON HYDROXYLASES; CHROMATOGRAPHY, MICELLAR ELECTROKINETIC CAPILLARY; CYTOCHROME P-450 ENZYME SYSTEM; DICLOFENAC; HUMANS; KETOCONAZOLE; MOLECULAR STRUCTURE; REPRODUCIBILITY OF RESULTS; SULFAPHENAZOLE;

EID: 41949115725     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2007.11.004     Document Type: Article

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