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Volumn 173, Issue 1, 2008, Pages 32-42

Protective effects of Ginkgo biloba against rat liver carcinogenesis

Author keywords

Chemoprevention; Diethylnitrosamine; Ginkgo biloba; GST P positive preneoplastic foci; Liver carcinogenesis; Putative initiated hepatocytes

Indexed keywords

CYCLINE; DIETHYLNITROSAMINE; GINKGO BILOBA EXTRACT; GLUTATHIONE S TRANSFERASE P; PROTEIN P53; TRANSFERASE; TRANSFORMING GROWTH FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 41949098914     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2008.01.012     Document Type: Article
Times cited : (25)

References (45)
  • 1
    • 0033974910 scopus 로고    scopus 로고
    • Ginkgo biloba: a living fossil
    • Jacobs B.P., and Browner W.S. Ginkgo biloba: a living fossil. Am. J. Med. 108 (2000) 341-342
    • (2000) Am. J. Med. , vol.108 , pp. 341-342
    • Jacobs, B.P.1    Browner, W.S.2
  • 2
    • 0141749421 scopus 로고    scopus 로고
    • Neuroprotective effects of Ginkgo biloba extract
    • Ahlemeyer B., and Krieglstein J. Neuroprotective effects of Ginkgo biloba extract. Cell Mol. Life Sci. 60 (2003) 1779-1792
    • (2003) Cell Mol. Life Sci. , vol.60 , pp. 1779-1792
    • Ahlemeyer, B.1    Krieglstein, J.2
  • 3
    • 0042169046 scopus 로고    scopus 로고
    • Ginkgo biloba extracts and cancer: a research area in its infancy
    • DeFeudis F.V., Papadopoulos V., and Drieu K. Ginkgo biloba extracts and cancer: a research area in its infancy. Fundam. Clin. Pharmacol. 17 (2003) 405-417
    • (2003) Fundam. Clin. Pharmacol. , vol.17 , pp. 405-417
    • DeFeudis, F.V.1    Papadopoulos, V.2    Drieu, K.3
  • 4
    • 16344375886 scopus 로고    scopus 로고
    • Biological activities of Ginkgo extracts
    • Boonkaew T., and Camper N.D. Biological activities of Ginkgo extracts. Phytomedicine 12 (2004) 318-323
    • (2004) Phytomedicine , vol.12 , pp. 318-323
    • Boonkaew, T.1    Camper, N.D.2
  • 5
    • 0033853197 scopus 로고    scopus 로고
    • Protective effect of ginkgo extract on rat brain with transient middle cerebral artery occlusion
    • Zhang W.R., Hayashi T., and Kitagawa H. Protective effect of ginkgo extract on rat brain with transient middle cerebral artery occlusion. Neurol. Res. 22 (2000) 517-521
    • (2000) Neurol. Res. , vol.22 , pp. 517-521
    • Zhang, W.R.1    Hayashi, T.2    Kitagawa, H.3
  • 6
    • 0034853406 scopus 로고    scopus 로고
    • Ginkgo biloba neuroprotection: therapeutic implications in Alzheimer's disease
    • Luo Y. Ginkgo biloba neuroprotection: therapeutic implications in Alzheimer's disease. J. Alzheimers Dis. 3 (2001) 401-407
    • (2001) J. Alzheimers Dis. , vol.3 , pp. 401-407
    • Luo, Y.1
  • 8
    • 33745860411 scopus 로고    scopus 로고
    • Effects of extract from Ginkgo biloba on carbon tetrachloride-induced liver injury in rats
    • He S.X., Luo J.Y., and Wang Y.P. Effects of extract from Ginkgo biloba on carbon tetrachloride-induced liver injury in rats. World J. Gastroenterol. 12 (2006) 3924-3928
    • (2006) World J. Gastroenterol. , vol.12 , pp. 3924-3928
    • He, S.X.1    Luo, J.Y.2    Wang, Y.P.3
  • 9
    • 33645763019 scopus 로고    scopus 로고
    • Protective effects of Ginkgo biloba against acetaminophen-induced toxicity in mice
    • Sener G., Omurtag G.Z., and Sehirli O. Protective effects of Ginkgo biloba against acetaminophen-induced toxicity in mice. Mol. Cell Biochem. 283 (2006) 39-45
    • (2006) Mol. Cell Biochem. , vol.283 , pp. 39-45
    • Sener, G.1    Omurtag, G.Z.2    Sehirli, O.3
  • 10
    • 33947286256 scopus 로고    scopus 로고
    • Antioxidant and hepatoprotective effects of Ginkgo biloba phytosomes in carbon tetrachloride-induced liver injury in rodents
    • Naik S.R., and Panda V.S. Antioxidant and hepatoprotective effects of Ginkgo biloba phytosomes in carbon tetrachloride-induced liver injury in rodents. Liver Int. 27 (2007) 393-399
    • (2007) Liver Int. , vol.27 , pp. 393-399
    • Naik, S.R.1    Panda, V.S.2
  • 11
    • 0037154807 scopus 로고    scopus 로고
    • Effects of extract of Ginkgo biloba leaves and its constituents on carcinogen-metabolizing enzyme activities and glutathione levels in mouse liver
    • Sasaki K., Hatta S., and Wada K. Effects of extract of Ginkgo biloba leaves and its constituents on carcinogen-metabolizing enzyme activities and glutathione levels in mouse liver. Life Sci. 70 (2002) 1657-1667
    • (2002) Life Sci. , vol.70 , pp. 1657-1667
    • Sasaki, K.1    Hatta, S.2    Wada, K.3
  • 12
    • 0038740798 scopus 로고    scopus 로고
    • Induction of the procarcinogen-activating CYP1A2 by a herbal dietary supplement in rats and humans
    • Ryu S.D., and Chung W.G. Induction of the procarcinogen-activating CYP1A2 by a herbal dietary supplement in rats and humans. Food Chem. Toxicol. 41 (2003) 861-866
    • (2003) Food Chem. Toxicol. , vol.41 , pp. 861-866
    • Ryu, S.D.1    Chung, W.G.2
  • 13
    • 2442534164 scopus 로고    scopus 로고
    • Inhibition of human P450 enzymes by multiple constituents of the Ginkgo biloba extract
    • Gaudineau C., Beckerman R., Welbourn S., and Auclair K. Inhibition of human P450 enzymes by multiple constituents of the Ginkgo biloba extract. Biochem. Biophys. Res. Commun. 318 (2004) 1072-1078
    • (2004) Biochem. Biophys. Res. Commun. , vol.318 , pp. 1072-1078
    • Gaudineau, C.1    Beckerman, R.2    Welbourn, S.3    Auclair, K.4
  • 14
    • 1942534088 scopus 로고    scopus 로고
    • Induction and recovery of hepatic drug metabolizing enzymes in rats treated with Ginkgo biloba extract
    • Sugiyama T., Kubota Y., Shinozuka K., Yamada S., Yamada K., and Umegaki K. Induction and recovery of hepatic drug metabolizing enzymes in rats treated with Ginkgo biloba extract. Food Chem. Toxicol. 42 (2004) 953-957
    • (2004) Food Chem. Toxicol. , vol.42 , pp. 953-957
    • Sugiyama, T.1    Kubota, Y.2    Shinozuka, K.3    Yamada, S.4    Yamada, K.5    Umegaki, K.6
  • 15
    • 0346685835 scopus 로고    scopus 로고
    • Effects of Ginkgo biloba extract on cell proliferation and cytotoxicity in human hepatocellular carcinoma cells
    • Chao J.C., and Chu C.C. Effects of Ginkgo biloba extract on cell proliferation and cytotoxicity in human hepatocellular carcinoma cells. World J. Gastroenterol. 10 (2004) 37-41
    • (2004) World J. Gastroenterol. , vol.10 , pp. 37-41
    • Chao, J.C.1    Chu, C.C.2
  • 16
    • 0036791446 scopus 로고    scopus 로고
    • Apoptosis of hepatoma cells SMMC-7721 induced by Ginkgo biloba seed polysaccharide
    • Chen Q., Yang G.W., and An L.G. Apoptosis of hepatoma cells SMMC-7721 induced by Ginkgo biloba seed polysaccharide. World J. Gastroenterol. 8 (2002) 832-836
    • (2002) World J. Gastroenterol. , vol.8 , pp. 832-836
    • Chen, Q.1    Yang, G.W.2    An, L.G.3
  • 18
    • 15244358528 scopus 로고    scopus 로고
    • Ginkgo biloba extract (EGb 761) induces apoptosis by the activation of caspase-3 in oral cavity cancer cells
    • Kim K.S., Rhee K.H., Yoon J.H., Lee J.G., Lee J.H., and Yoo J.B. Ginkgo biloba extract (EGb 761) induces apoptosis by the activation of caspase-3 in oral cavity cancer cells. Oral Oncol. 41 (2005) 383-389
    • (2005) Oral Oncol. , vol.41 , pp. 383-389
    • Kim, K.S.1    Rhee, K.H.2    Yoon, J.H.3    Lee, J.G.4    Lee, J.H.5    Yoo, J.B.6
  • 19
    • 0035005844 scopus 로고    scopus 로고
    • Chemopreventive effect of Ginkgo biloba extract against benzo(a)pyrene-induced forestomach carcinogenesis in mice: amelioration of doxorubicin cardiotoxicity
    • Agha A.M., El-Fattah A.A., Al-Zuhair H.H., and Al-Rikabi A.C. Chemopreventive effect of Ginkgo biloba extract against benzo(a)pyrene-induced forestomach carcinogenesis in mice: amelioration of doxorubicin cardiotoxicity. J. Exp. Clin. Cancer Res. 20 (2001) 39-50
    • (2001) J. Exp. Clin. Cancer Res. , vol.20 , pp. 39-50
    • Agha, A.M.1    El-Fattah, A.A.2    Al-Zuhair, H.H.3    Al-Rikabi, A.C.4
  • 20
    • 2942558654 scopus 로고    scopus 로고
    • Preventive effects of extract of leaves of ginkgo (Ginkgo biloba) and its component bilobalide on azoxymethane-induced colonic aberrant crypt foci in rats
    • Suzuki R., Kohno H., and Sugie S. Preventive effects of extract of leaves of ginkgo (Ginkgo biloba) and its component bilobalide on azoxymethane-induced colonic aberrant crypt foci in rats. Cancer Lett. 210 (2004) 159-169
    • (2004) Cancer Lett. , vol.210 , pp. 159-169
    • Suzuki, R.1    Kohno, H.2    Sugie, S.3
  • 21
    • 0026484103 scopus 로고
    • Predictive value of hepatic preneoplastic lesions as indicators of carcinogenic response
    • Vainio H., Magee P., McGregor D., and McMichael A.J. (Eds), International Agency of Research on Cancer, Lyon
    • Bannasch P., and Zerban H. Predictive value of hepatic preneoplastic lesions as indicators of carcinogenic response. In: Vainio H., Magee P., McGregor D., and McMichael A.J. (Eds). Mechanism of Carcinogenesis in Risk Identification, IARC Scientific Publication 116 (1992), International Agency of Research on Cancer, Lyon 389-427
    • (1992) Mechanism of Carcinogenesis in Risk Identification, IARC Scientific Publication 116 , pp. 389-427
    • Bannasch, P.1    Zerban, H.2
  • 22
    • 0037261429 scopus 로고    scopus 로고
    • Relevance of hepatic preneoplasia for human hepatocarcinogenesis
    • Su Q., and Bannasch P. Relevance of hepatic preneoplasia for human hepatocarcinogenesis. Toxicol. Pathol. 31 (2003) 126-133
    • (2003) Toxicol. Pathol. , vol.31 , pp. 126-133
    • Su, Q.1    Bannasch, P.2
  • 23
    • 0023833075 scopus 로고
    • Reciprocal relationship between development of glutathione S-transferase positive liver foci and proliferation of surrounding hepatocytes in rats
    • Tatematsu M., Aoki T., Kagawa M., Mera Y., and Ito N. Reciprocal relationship between development of glutathione S-transferase positive liver foci and proliferation of surrounding hepatocytes in rats. Carcinogenesis 9 (1988) 221-225
    • (1988) Carcinogenesis , vol.9 , pp. 221-225
    • Tatematsu, M.1    Aoki, T.2    Kagawa, M.3    Mera, Y.4    Ito, N.5
  • 24
    • 0023215479 scopus 로고
    • Single GST-P positive liver cells-putative initiated hepatocytes
    • Moore M.A., Nakagawa K., Satoh K., Ishikawa T., and Sato K. Single GST-P positive liver cells-putative initiated hepatocytes. Carcinogenesis 8 (1987) 483-486
    • (1987) Carcinogenesis , vol.8 , pp. 483-486
    • Moore, M.A.1    Nakagawa, K.2    Satoh, K.3    Ishikawa, T.4    Sato, K.5
  • 25
    • 0024452919 scopus 로고
    • Transient induction of single GST-P positive hepatocytes by DEN
    • Satoh K., Hatayama I., and Tateoka N. Transient induction of single GST-P positive hepatocytes by DEN. Carcinogenesis 10 (1989) 2107-2111
    • (1989) Carcinogenesis , vol.10 , pp. 2107-2111
    • Satoh, K.1    Hatayama, I.2    Tateoka, N.3
  • 26
    • 0032947970 scopus 로고    scopus 로고
    • Marriage of a medium-term liver model to surrogate markers: a practical approach for risk and benefit assessment
    • Moore M.A., Tsuda H., and Tamano S. Marriage of a medium-term liver model to surrogate markers: a practical approach for risk and benefit assessment. Toxicol. Pathol. 27 (1999) 237-242
    • (1999) Toxicol. Pathol. , vol.27 , pp. 237-242
    • Moore, M.A.1    Tsuda, H.2    Tamano, S.3
  • 27
    • 0037648908 scopus 로고    scopus 로고
    • A medium-term rat liver bioassay for rapid in vivo detection of carcinogenic potential of chemicals
    • Ito N., Tamano S., and Shirai T. A medium-term rat liver bioassay for rapid in vivo detection of carcinogenic potential of chemicals. Cancer Sci. 94 (2003) 3-8
    • (2003) Cancer Sci. , vol.94 , pp. 3-8
    • Ito, N.1    Tamano, S.2    Shirai, T.3
  • 29
    • 0023858438 scopus 로고
    • Enhancing effect of various hepatocarcinogens on induction of preneoplastic glutathione S-transferase placental form positive foci in rats-an approach for a new medium-term bioassay system
    • Ito N., Tsuda H., Tatematsu M., Inoue T., Tagawa Y., Aoki T., Uwagawa S., Kagawa M., Ogiso T., and Masui T. Enhancing effect of various hepatocarcinogens on induction of preneoplastic glutathione S-transferase placental form positive foci in rats-an approach for a new medium-term bioassay system. Carcinogenesis 9 (1988) 387-394
    • (1988) Carcinogenesis , vol.9 , pp. 387-394
    • Ito, N.1    Tsuda, H.2    Tatematsu, M.3    Inoue, T.4    Tagawa, Y.5    Aoki, T.6    Uwagawa, S.7    Kagawa, M.8    Ogiso, T.9    Masui, T.10
  • 30
    • 0032765190 scopus 로고    scopus 로고
    • The nomenclature of cell death: recommendations of an ad hoc Committee of the Society of Toxicologic Pathologists
    • Levin S., Bucci T.J., and Cohen S.M. The nomenclature of cell death: recommendations of an ad hoc Committee of the Society of Toxicologic Pathologists. Toxicol. Pathol. 27 (1999) 484-490
    • (1999) Toxicol. Pathol. , vol.27 , pp. 484-490
    • Levin, S.1    Bucci, T.J.2    Cohen, S.M.3
  • 31
    • 0029780653 scopus 로고    scopus 로고
    • N-Nitrosodiethylamine mechanistic data and risk assessment: bioactivation, DNA-adduct formation, mutagenicity, and tumor initiation
    • Verna L., Whysner J., and Williams G.M. N-Nitrosodiethylamine mechanistic data and risk assessment: bioactivation, DNA-adduct formation, mutagenicity, and tumor initiation. Pharmacol. Ther. 71 (1996) 57-81
    • (1996) Pharmacol. Ther. , vol.71 , pp. 57-81
    • Verna, L.1    Whysner, J.2    Williams, G.M.3
  • 32
    • 0026332478 scopus 로고
    • Mechanistic and statistical insight into the large carcinogenesis bioassays on N-nitrosodiethylamine and N-nitrosodimethylamine
    • Swenberg J.A., Hoel D.G., and Magee P.N. Mechanistic and statistical insight into the large carcinogenesis bioassays on N-nitrosodiethylamine and N-nitrosodimethylamine. Cancer Res. 51 (1991) 6409-6414
    • (1991) Cancer Res. , vol.51 , pp. 6409-6414
    • Swenberg, J.A.1    Hoel, D.G.2    Magee, P.N.3
  • 33
    • 0030940501 scopus 로고    scopus 로고
    • Involvement of 8-hydroxyguanine formation in the initiation of rat liver carcinogenesis by low dose levels of N-nitrosodiethylamine
    • Nakae D., Kobayashi Y., Akai H., Andoh N., Satoh H., Ohashi K., Tsutsumi M., and Konishi Y. Involvement of 8-hydroxyguanine formation in the initiation of rat liver carcinogenesis by low dose levels of N-nitrosodiethylamine. Cancer Res. 57 (1997) 1281-1287
    • (1997) Cancer Res. , vol.57 , pp. 1281-1287
    • Nakae, D.1    Kobayashi, Y.2    Akai, H.3    Andoh, N.4    Satoh, H.5    Ohashi, K.6    Tsutsumi, M.7    Konishi, Y.8
  • 34
    • 0029805480 scopus 로고    scopus 로고
    • Diethylnitrosamine exposure-responses for DNA damage, centrilobular cytotoxicity, cell proliferation and carcinogenesis in rat liver exhibits some non-linearities
    • Williams G.M., Iatropoulos M.J., and Wang C.X. Diethylnitrosamine exposure-responses for DNA damage, centrilobular cytotoxicity, cell proliferation and carcinogenesis in rat liver exhibits some non-linearities. Carcinogenesis 17 (1996) 2253-2258
    • (1996) Carcinogenesis , vol.17 , pp. 2253-2258
    • Williams, G.M.1    Iatropoulos, M.J.2    Wang, C.X.3
  • 35
    • 0031927039 scopus 로고    scopus 로고
    • Wild-type p53 expression in liver tissue and in enzyme-altered foci: an in vivo investigation on diethylnitrosamine-treated rats
    • Lennartsson P., Hogberg J., and Stenius U. Wild-type p53 expression in liver tissue and in enzyme-altered foci: an in vivo investigation on diethylnitrosamine-treated rats. Carcinogenesis 19 (1998) 1231-1237
    • (1998) Carcinogenesis , vol.19 , pp. 1231-1237
    • Lennartsson, P.1    Hogberg, J.2    Stenius, U.3
  • 36
    • 0032913852 scopus 로고    scopus 로고
    • P53 expression and TGF-alpha-induced replication of hepatocytes isolated from rats exposed to the carcinogen diethylnitrosamine
    • Lennartsson P., Stenius U., and Hogberg J. P53 expression and TGF-alpha-induced replication of hepatocytes isolated from rats exposed to the carcinogen diethylnitrosamine. Cell Biol. Toxicol. 15 (1999) 31-39
    • (1999) Cell Biol. Toxicol. , vol.15 , pp. 31-39
    • Lennartsson, P.1    Stenius, U.2    Hogberg, J.3
  • 37
    • 0030941458 scopus 로고    scopus 로고
    • P53: the cellular gatekeeper for growth and division
    • Levine A.J. P53: the cellular gatekeeper for growth and division. Cell 88 (1997) 323-331
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 39
    • 0027881693 scopus 로고
    • Comparison of proliferating cell nuclear antigen to tritiated thymidine as a marker of proliferating hepatocytes in rats
    • Foley J., Ton T., Maronpot R., Butterworth B., and Goldsworthy T.L. Comparison of proliferating cell nuclear antigen to tritiated thymidine as a marker of proliferating hepatocytes in rats. Environ. Health Perspect. 5 (1993) 199-205
    • (1993) Environ. Health Perspect. , vol.5 , pp. 199-205
    • Foley, J.1    Ton, T.2    Maronpot, R.3    Butterworth, B.4    Goldsworthy, T.L.5
  • 40
    • 0041531109 scopus 로고
    • Transforming growth factor alpha may be a physiological regulator of liver regeneration by means of an autocrine mechanism
    • Mead J.E., and Fausto N. Transforming growth factor alpha may be a physiological regulator of liver regeneration by means of an autocrine mechanism. Proc. Natl. Acad. Sci. U.S.A. 86 (1989) 1558-1562
    • (1989) Proc. Natl. Acad. Sci. U.S.A. , vol.86 , pp. 1558-1562
    • Mead, J.E.1    Fausto, N.2
  • 41
    • 33744550042 scopus 로고    scopus 로고
    • Possible tumour development from double positive foci for TGF-alpha and GST-P observed in early stages on rat hepatocarcinogenesis
    • Gitano M., Wada J., Ariki Y., Kato M., Wanibuchi H., Morimura K., Hidaka T., Hosoe K., and Fukushima S. Possible tumour development from double positive foci for TGF-alpha and GST-P observed in early stages on rat hepatocarcinogenesis. Cancer Sci. 97 (2006) 478-483
    • (2006) Cancer Sci. , vol.97 , pp. 478-483
    • Gitano, M.1    Wada, J.2    Ariki, Y.3    Kato, M.4    Wanibuchi, H.5    Morimura, K.6    Hidaka, T.7    Hosoe, K.8    Fukushima, S.9
  • 42
    • 18444374697 scopus 로고    scopus 로고
    • P53 may positively regulate hepatocyte proliferation in rats
    • Inoue Y., Tomiya T., and Yanase M. P53 may positively regulate hepatocyte proliferation in rats. Hepatology 36 (2002) 336-344
    • (2002) Hepatology , vol.36 , pp. 336-344
    • Inoue, Y.1    Tomiya, T.2    Yanase, M.3
  • 43
    • 0036319426 scopus 로고    scopus 로고
    • Anomalous elevation of glutathione S-transferase P-form (GST-P) in the elementary process of epigenetic initiation of chemical hepatocarcinogenesis in rats
    • Satoh K., and Hatayama I. Anomalous elevation of glutathione S-transferase P-form (GST-P) in the elementary process of epigenetic initiation of chemical hepatocarcinogenesis in rats. Carcinogenesis 23 (2002) 1193-1198
    • (2002) Carcinogenesis , vol.23 , pp. 1193-1198
    • Satoh, K.1    Hatayama, I.2
  • 44
    • 33845327099 scopus 로고    scopus 로고
    • Biomakers for oxidative stress status of DNA, lipids, and proteins in vitro and in vivo cancer research
    • Hwang E.S., and Kim G.H. Biomakers for oxidative stress status of DNA, lipids, and proteins in vitro and in vivo cancer research. Toxicology 229 (2007) 1-10
    • (2007) Toxicology , vol.229 , pp. 1-10
    • Hwang, E.S.1    Kim, G.H.2
  • 45
    • 0030331755 scopus 로고    scopus 로고
    • L.W. Wattenberg, Inhibition of tumorigenesis in animals, in: B.W. Stewart, D. McGregor, P. Kleihwes (Eds.), Principles of Chemoprevention, IARC Scientific Publication 139, International Agency of Research on Cancer, Lyon, 1996, pp. 151-158.
    • L.W. Wattenberg, Inhibition of tumorigenesis in animals, in: B.W. Stewart, D. McGregor, P. Kleihwes (Eds.), Principles of Chemoprevention, IARC Scientific Publication 139, International Agency of Research on Cancer, Lyon, 1996, pp. 151-158.


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