Metabolism of 17α-hydroxyprogesterone caproate by hepatic and placental microsomes of human and baboons

Biochemical Pharmacology

Volumn 75, Issue 9, 2008, Pages 1848-1857

  Yan, Ru ^a   Nanovskaya, Tatiana N ^a   Zharikova, Olga L ^a   Mattison, Donald R ^b   Hankins, Gary D V ^a   Ahmed, Mahmoud S ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

17 Hydroxyprogesterone caproate; Baboon liver; Baboon placenta; Human liver; Human placenta; Metabolism; Microsomes; Preterm delivery

Indexed keywords

HYDROXYPROGESTERONE CAPROATE; HYDROXYPROGESTERONE;

ANIMAL TISSUE; ARTICLE; DRUG METABOLISM; DRUG STRUCTURE; DRUG USE; HUMAN; HUMAN TISSUE; LIVER MICROSOME; MICROSOME; NONHUMAN; PAPIO CYNOCEPHALUS; PLACENTA; PLACENTAL TRANSFER; PREGNANCY; PRIORITY JOURNAL; QUANTITATIVE ASSAY; VALIDATION PROCESS; ANIMAL; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; LIVER; METABOLISM; SPECIES DIFFERENCE;

17-ALPHA-HYDROXYPROGESTERONE; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; HUMANS; LIVER; MICROSOMES; MICROSOMES, LIVER; PAPIO CYNOCEPHALUS; PLACENTA; SPECIES SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 41949095956     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2008.01.013     Document Type: Article

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