Meta-analysis of randomized, controlled treatment trials for pediatric obsessive-compulsive disorder

Journal of Child Psychology and Psychiatry and Allied Disciplines

Volumn 49, Issue 5, 2008, Pages 489-498

  Watson, Hunna J ^a   Rees, Clare S ^a  

^a CURTIN UNIVERSITY   (Australia)

Author keywords

Child adolescent obsessive compulsive disorder; Cognitive behavioral therapy; Drug therapy; Meta analysis; Pediatric; Pharmacology; Psychotherapy

Indexed keywords

BUSPIRONE; CITALOPRAM; CLOMIPRAMINE; FLUOXETINE; FLUVOXAMINE; PAROXETINE; SERTRALINE; SUMATRIPTAN;

ARTICLE; CHILD; CLINICAL PRACTICE; CLINICAL TRIAL; COGNITIVE THERAPY; CONTROLLED CLINICAL TRIAL; EVIDENCE BASED MEDICINE; FEMALE; HUMAN; MALE; META ANALYSIS; OBSESSIVE COMPULSIVE DISORDER; PSYCHOTHERAPY; RANDOMIZED CONTROLLED TRIAL; SYSTEMATIC REVIEW; TREATMENT RESPONSE;

ADOLESCENT; ADULT; CHILD; COGNITIVE THERAPY; COMBINED MODALITY THERAPY; DRUG THERAPY; HUMANS; OBSESSIVE-COMPULSIVE DISORDER; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

EID: 41849146755     PISSN: 00219630     EISSN: 14697610     Source Type: Journal    
DOI: 10.1111/j.1469-7610.2007.01875.x     Document Type: Article

References (46)

1. Abramowitz, J.S., Whiteside, S.P. Deacon, B.J. (2005). The effectiveness of treatment for pediatric obsessive-compulsive disorder: A meta-analysis. Behavior Therapy, 36, 55 63.
2. Barrett, P., Healy-Farrell, L. March, J.S. (2004). Cognitive-behavioral family treatment of childhood obsessive-compulsive disorder: A controlled trial. Journal of the American Academy of Child and Adolescent Psychiatry, 43, 46 62.
3. Barrett, P.M. Healy, L.J. (2003). An examination of the cognitive processes involved in childhood obsessive-compulsive disorder. Behaviour Research and Therapy, 41, 285 289.
4. Bolton, D. Perrin, S. (in press). Evaluation of exposure and response-prevention for obsessive compulsive disorder in childhood and adolescence. Journal of Behavior Therapy and Experimental Psychiatry.
5. Deeks, J.J., Altman, D.G. Bradburn, M.J. (2001). Statistical methods for examining heterogeneity and combining results from several studies in meta-analysis. In M. Egger, G. Davey Smith D.G. Altman (Eds Systematic reviews in health care: Meta-analysis in context (2nd edn, pp. 285 312). London : BMJ Publication Group.
6. DeVeaugh-Geiss, J., Moroz, B. Biederman, J. (1992). Clomipramine hydrochloride in childhood and adolescent obsessive-compulsive disorder: A multicenter trial. Journal of the American Academy of Child and Adolescent Psychiatry, 31, 45 49.
7. Egger, M., Davey Smith, G., Schneider, M. Minder, C. (1997). Bias in meta-analyses detected by a simple graphical test. British Medical Journal, 315, 629 634.
8. Field, A.P. (2003). The problems in using fixed-effects models of meta-analysis on real-world data. Understanding Statistics, 2, 105 124.
9. Flament, M.F., Rapoport, J.L., Berg, C.J., Sceery, W., Kilts, C., Mellstrom, B., et al. (1985). Clomipramine treatment of childhood obsessive-compulsive disorder: A double-blind controlled study. Archives of General Psychiatry, 42, 977 983.
10. Freeman, J.B., Choate-Summers, M.L., Moore, P.S., Garcia, A.M., Sapyta, J.J., Leonard, H.L., et al. (2007). Cognitive behavioral treatment for young children with obsessive-compulsive disorder. Biological Psychiatry, 61, 337 343.
11. Geller, D.A., Biederman, J., Stewart, S.E., Mullin, B., Martin, A., Spencer, T., et al. (2003a). Which SSRI? A meta-analysis of pharmacotherapy trials in pediatric obsessive-compulsive disorder. The American Journal of Psychiatry, 160, 1919 1928.
12. Geller, D.A., Hoog, S.L., Heiligenstein, J.H., Ricardi, R.K., Tamura, R., Kluszynski, S., et al. (2001). Fluoxetine treatment for obsessive-compulsive disorder in children and adolescents: A placebo-controlled clinical trial. Journal of the American Academy of Child and Adolescent Psychiatry, 40, 773 779.
13. Geller, D.A., Stewart, S.E., Farrell, C. Emslie, G. (2003b). Impact of comorbidity on treatment response to paroxetine in pediatric obsessive-compulsive disorder: Is the use of exclusion criteria empirically supported in randomized clinical trials Journal of Child and Adolescent Psychopharmacology, 13, 19 29.
14. Geller, D.A., Wagner, K.D., Emslie, G., Murphy, T., Carpenter, D.J., Wetherhold, E., et al. (2004). Paroxetine treatment in children and adolescents with obsessive-compulsive disorder: A randomized, multicenter, double-blind, placebo-controlled trial. Journal of the American Academy of Child and Adolescent Psychiatry, 43, 1387 1396.
15. Glass, G. (1976). Primary, secondary, and meta-analysis of research. Educational Researcher, 5, 3 8.
16. Goodman, W.K., Price, L.H. Rasmussen, S.A. (1989). The Yale-Brown Obsessive-Compulsive Scale I: Development, use, and reliability. Archives of General Psychiatry, 46, 1006 1011.
17. Grencavege, L., Bootzin, R. Shoham, V. (1993). Specific and non-specific effects in therapy. In C.G. Costello (Ed Basic issues in psychopathology (pp. 359 376). New York : Guilford.
18. Guggisberg, K.W. (2005). Methodological review and meta-analysis of treatments for child and adolescent obsessive-compulsive disorder. Unpublished PhD thesis. University of Utah, Salt Lake City.
19. Hedges, L.V. Olkin, I. (1985). Statistical methods for meta-analysis. Orlando, FL : Academic Press.
20. Higgins, J.P.T. Green, S. (Eds 2005). Cochrane handbook for systematic reviews of interventions 4.2.5 [updated May, 2005]. In The Cochrane Library, Issue 3. Chichester, UK : John Wiley & Sons, Ltd.
21. Himle, J.A. (2003). Group cognitive behavioral therapy versus group anxiety management for adolescent OCD: A randomized, controlled pilot study. Poster presented at the National Conference of the Anxiety Disorders Association of America, Toronto, Canada.
22. Hunter, J.E. Schmidt, F.L. (2000). Fixed effects vs. random effects meta-analysis models: Implications for cumulative research knowledge. International Journal of Selection and Assessment, 8, 275 292.
23. Kobak, K.A., Greist, J.H., Jefferson, J.W., Katzelnick, D.J. Henk, H.J. (1998). Behavioral versus pharmacological treatments of obsessive-compulsive disorder: A meta-analysis. Psychopharmacology, 136, 205 216.
24. Leonard, H.L., Swedo, S.E., Lenane, M.C., Rettew, D.C., Cheslow, D.L., Hamburger, S.D., et al. (1991). A double-blind desipramine substitution during long-term clomipramine treatment in children and adolescents with obsessive-compulsive disorder. Archives of General Psychiatry, 48, 922 927.
25. Leonard, H.L., Swedo, S.E., Rapoport, J.L., Coby, E.V., Lenane, M.C., Cheslow, D.L., et al. (1989). Treatment of obsessive-compulsive disorder with clomipramine and desipramine in children and adolescents: A double-blind crossover comparison. Archives of General Psychiatry, 46, 1088 1092.
26. Liebowitz, M.R., Turner, S.M., Piacentini, J., Beidel, D.C., Clarvit, S.R., Davies, S.O., et al. (2002). Fluoxetine in children and adolescents with OCD: A placebo-controlled trial. Journal of the American Academy of Child and Adolescent Psychiatry, 41, 1431 1438.
27. Lipsey, M.W. Wilson, D.B. (1993). The efficacy of psychological, educational, and behavioral treatment: Confirmation from meta-analysis. American Psychologist, 48, 1181 1209.
28. March, J.S., Biederman, J., Wolkow, R., Safferman, A., Mardekian, J., Cook, E.H., et al. (1998). Sertraline in children and adolescents with obsessive-compulsive disorder: A multicenter randomized controlled trial. Journal of the American Medical Association, 280, 1752 1756.
29. March, J.S. Curry, J.S. (1998). Predicting the outcome of treatment. Journal of Abnormal Child Psychology, 26, 39 51.
30. March, J.S., Frances, A., Carpenter, D. Kahn, D.A. (1997). The expert consensus guideline series: Treatment of obsessive-compulsive disorder. Journal of Clinical Psychiatry, 58, 1 72.
31. March, J.S., Johnston, H., Jefferson, J.W., Kobak, K.A. Greist, J.H. (1990). Do subtle neurological impairments predict treatment resistance to clomipramine in children and adolescents with obsessive-compulsive disorder. Journal of Child and Adolescent Psychopharmacology, 1, 133 140.
32. March, J.S. Mulle, K. (1998). OCD in children and adolescents: A cognitive-behavioral treatment manual. New York : Guilford.
33. O'Kearney, R.T., Anstey, K.J. von Sanden, C. (2006). Behavioural and cognitive behavioural therapy for obsessive compulsive disorder in children and adolescents. Cochrane Database of Systematic Reviews, Issue 4. Art. No.:CD004856. DOI: 10.1002/14651858.CD004856.pub2, b.
34. Orwin, R. (1983). A fail safe N for effect sizes in meta-analysis. Journal of Educational Statistics, 8, 157 159.
35. Pediatric OCD Treatment Study [POTS] Team. (2004). Cognitive-behavior therapy, sertraline, and their combination for children and adolescents with obsessive-compulsive disorder. Journal of the American Medical Association, 292, 1969 1976.
36. Perlmutter, S.J., Leitman, S.F., Garvey, M.A., Hamburger, S., Feldman, E., Leonard, H.L., et al. (1999). Therapeutic plasma exchange and intravenous immunoglobulin for obsessive-compulsive disorder and tic disorders in childhood. Lancet, 354, 1153 1158.
37. Phillips, A.S. (2003). A meta-analysis of treatments for pediatric obsessive-compulsive disorder. Unpublished PhD, Kansas State University, Kansas.
38. Piacentini, J., Bergman, R.L., Kellar, M. McCracken, J. (2003). Functional impairment in children and adolescents with obsessive-compulsive disorder. Journal of Child and Adolescent Psychopharmacology, 13, S61 69.
39. Riddle, M.A., Reeve, E.A., Yaryura-Tobias, J.A., Yang, H.M., Claghorn, J.L., Gaffney, G., et al. (2001). Fluvoxamine for children and adolescents with obsessive-compulsive disorder: A randomized, controlled, multicenter trial. Journal of the American Academy of Child and Adolescent Psychiatry, 40, 222 229.
40. Riddle, M.A., Scahill, L., King, R.A., Hardin, M.T., Anderson, G.M., Ort, S.I., et al. (1992). Double-blind, crossover trial of fluoxetine and placebo in children and adolescents with obsessive-compulsive disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 31, 1062 1069.
41. Rosenthal, R. (1979). The 'file drawer problem' and tolerance for null results. Psychological Bulletin, 86, 638 641.
42. Scahill, L., Riddle, M.A., King, R.A., Hardin, M.T., Rasmussen, A., Makuch, R.W., et al. (1997a). Fluoxetine has no marked effect on tic symptoms in patients with Tourette's syndrome: A double-blind placebo-controlled study. Journal of the American Academy of Child and Adolescent Psychiatry, 7, 75 85.
43. Scahill, L., Riddle, M., McSwiggin-Hardin, M., Ort, S., King, R., Goodman, W., et al. (1997b). Children's Yale-Brown Obsessive Compulsive Scale: Reliability and validity. Journal of the American Academy of Child and Adolescent Psychiatry, 36, 844 852.
44. Valderhaug, R., Gotestam, K.G. Larsson, B. (2004). Clinicians' views on management of obsessive-compulsive disorders in children and adolescents. Nordic Journal of Psychiatry, 58, 125 132.
45. Weisz, J.R., Donenberg, G.R. Han, S.S. (1995). Bridging the gap between laboratory and clinic in child and adolescent psychotherapy. Journal of Consulting and Clinical Psychology, 63, 688 701.
46. Wewetzer, C., Jans, T., Muller, B., Neudorfl, A., Bucherl, U., Remschmidt, H., et al. (2001). Long-term outcome and prognosis of obsessive-compulsive disorder with onset in childhood or adolescence. European Child and Adolescent Psychiatry, 10, 37 46.