Transgenic λ medaka as a new model for germ cell mutagenesis

Environmental and Molecular Mutagenesis

Volumn 49, Issue 3, 2008, Pages 173-184

  Winn, Richard N ^a   Majeske, Audrey J ^b,c   Jagoe, Charles H ^b   Glenn, Travis C ^b   Smith, Michael H ^b   Norris, Michelle B ^a  

^a UNIVERSITY OF GEORGIA   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

^c GEORGE WASHINGTON UNIVERSITY   (United States)

Author keywords

Cll gene; Genomic instability; Germline; Mutations

Indexed keywords

ETHYLNITROSOUREA; MUTAGENIC AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; FERTILIZATION; GENE FREQUENCY; GENE MUTATION; GENE TARGETING; GENETIC MODEL; GENETIC RISK; GENOMIC INSTABILITY; GERM CELL; MALE; MEIOSIS; MOLECULAR GENETICS; MOSAICISM; MUTAGENESIS; MUTATIONAL ANALYSIS; NONHUMAN; ORYZIAS; PREVALENCE; PROGENY; SPERMATID; SPERMATOGONIUM; SPERMATOZOON; TRANSGENIC ANIMAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ETHYLNITROSOUREA; GERM CELLS; MALE; MODELS, ANIMAL; MUTAGENESIS; MUTAGENS; ORYZIAS; TRANSCRIPTION FACTORS; VIRAL PROTEINS;

ORYZIINAE;

EID: 41849129275     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.20364     Document Type: Article

References (58)

1. Amanuma K, Takeda H, Amanuma H, Aoki Y. 2000. Transgenic zebra-fish for detecting mutations caused by compounds in aquatic environments. Nat Biotechnol 18:62-65.
2. Barber R, Plumb MA, Boulton E, Roux I, Dubrova YE. 2002. Elevated mutation rates in the germ line of first- and second- generation offspring of irradiated male mice. Proc Natl Acad Sci USA 99:6877-6882.
3. Barber RC, Dubrova YE. 2006. The offspring of irradiated parents, are they stable? Mutat Res 598:50-60.
4. Barnett LB, Tyl RW, Shane BS, Shelby MD, Lewis SE. 2002. Transmission of mutations in the lacl transgene to the offspring of ENU-treated Big Blue® mice. Environ Mol Mutagen 40:251-257.
5. Boerrigter M, Dolle M, Martus H, Gossen JA, Vijg J. 1995. Plasmid based transgenic mouse model for studying in vivo mutations. Nature 377:657-659.
6. Burkhart JG, Winn RN, Van Beneden RJ, Malling HV. 1993. Spontaneous and induced mutagenesis in transgenic animals containing ΦX174. Environ Mol Mutant 21 (Suppl. 12):9.
7. Cachot J, Law M, Pottier D, Peluhet L, Norris M, Budzinski H, Winn R. 2007. Characterization of toxic effects of sediment-associated organic pollutants using λ transgenic medaka. Environ Sci Technol 41:7830-7836.
8. David WM, Mitchell DL, Walter RB. 2004. DNA repair in hybrid fish of the genus Xiphophorus. Comp Biocbem Physiol C Toxicol Pharmacol 138:301-309.
9. Dubrova YE, Plumb M, Gutierrez B, Boulton E, Jeffreys AJ. 2000. Genome stability - Transgenerational mutation by radiation. Nature 405:37.
10. Favor J, Neuhauser-Klaus A, Ehling UH. 1990. The frequency of dominant cataract and recessive specific-locus mutations and mutation mosaics in F1 mice derived from post-spermatogonial treatment with ethylnitrosourea. Mutat Res 229:105-114.
11. Friedberg EC, Walker GC, Siede W. 1995. DNA Repair and Mutagenesis. Washington, DC: ASM Press.
12. Generoso WM, Bishop JB, Gosslee DG, Newell GW, Sheu CJ, Halle Ev. 1980. Heritable translocation test in mice. Mutat Res 76:191-215.
13. Geter DR, Winn RN, Fournie JW, Norris MB, DeAngelo AB, Hawkins WE. 2004. MX [3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone], a drinking water carcinogen, does not induce mutations in the liver of cll transgenic medaka. J Toxicol Environ Health 67:373-383.
14. Gossen JA, De Leeuw WJF, Tan CHT, Zwarthoff EC, Berends F, Lohman PHM, Knook DL, Vijg J. 1989. Efficient rescue of integrated shuttle vectors from transgenic mice: A model for studying mutations in vivo. Proc Natl Acad Sci USA 86:7971-7975.
15. Green PM, Gianelli F. 1994. Direct sequencing of PCR-amplified DNA. Mol Biotech 1:117-124.
16. Hall JG. 1988. Review and hypotheses: Somatic mosaicism - Observations related to clinical genetics. Am J Hum Genet 43:355-363.
17. Harbach PR, Zimmer DM, Filipunas AL, Matters WB, Aaron CS. 1998. Spontaneous and ENU-induced ell mutation spectra in Big Blue® mice. Environ Mol Mutant 31(Suppl. 29):14.
18. Jakubczak JL, Medina G, French JE, Muller WJ, Paul B, Adhya S, Garges S. 1996. Analysis of genetic instability during mammary tumor progression using a novel selection-based assay for in vivo mutations in a bacteriophage λ transgene target. Proc Natl Acad Sci USA 93:9073-9078.
19. Kasahara M, Naruse K, Sasaki S, Nakatani Y, Qu W, Ahsan B, Yamada T, Nagayasu Y, Doi K, Kasai Y, Jindo T, Kobayashi D, Shimada A, Toyoda A, Kuroki Y, Fujiyama A, Sasaki T, Shimizu A, Asakawa S, Shimizu N, Hashimoto S, Yang J, Lee Y, Matsushima K, Sugano S, Sakaizumi M, Narita T, Ohishi K, Haga S, Ohta F, Nomoto H, Nogata K, Morishita T, Endo T, Shin-I T, Takeda H, Morishita S, Kohara Y. 2007. The medaka draft genome and insights into vertebrate genome evolution. Nature 447:714-719.
20. Kohler SW, Provost GS, Kretz PL, Fieck A, Bullock WO, Sorge JA, Putman DL, Short JM. 1991. Analysis of spontaneous and induced mutations in transgenic mice using a lambda ZAP®/lacl shuttle vector. Environ Mol Mutagen 18:316-321.
21. Lawrence CW. 2002. Cellular roles of DNA polymerase ζ and Rev1 protein. DNA Repair 1:425-435.
22. Lawrence CW, Banerjee S, Borden A, LeClerk J. 1990. T-T Cyclobutane dimers are misinstructive, rather than non-instructive, mutagenic lesions. Mol Gen Genet 222:166-168.
23. Manjanatha MG, Chen JB, Shaddock JGJ, Harris AJ, Shelton SD, Casciano DA. 1996. Molecular analysis of lacl mutations in Rat2™ cells exposed to 7, 12- dimethylbenz[a]anthracene: Evidence for DNA sequence and DNA strand biases for mutation. Mutat Res 372:53-64.
24. McElroy A, Bogler A, Weisbaum D, Norris M, Mendelman L, Setlow R, Winn R. 2006. Uptake, metabolism, mutant frequencies and mutational spectra in lambda transgenic medaka embryos exposed to benzo(a)pyrene dosed sediments. Mar Environ Res 62:S273-S277.
25. Morgan WF. 2003. Is there a common mechanism underlying genomic instability, bystander effects and other nontargeted effects of exposure to ionizing radiation? Oncogene 22:7094-7099.
26. Niwa O. 2003. Induced genomic instability in irradiated germ cells and in the offspring; reconciling discrepancies among the human and animal studies. Oncogene 22:7078-7086.
27. 1 mice born to irradiated spermatozoa. Proc Natl Acad Sci USA 98:1705-1710.
28. Postlethwait JH, Yan Y-L, Gates MA, Horne S, Amores A, Brownlie A, Donovan A, Egan ES, Force A, Gong Z, Goutel C, Fritz A, Kelsh R, Knapik E, Liao E, Paw B, Ransom D, Singer A, Thomson M, Abduljabbar TS, Yelick P, Beier D, Joly JS, Larhammar D, Rosa F, Westerfield M, Zon LI, Johnson SL, Talbot WS. 1998. Vertebrate genome evolution and the zebrafish gene map. Nat Genet 18:345-349.
29. Postlethwait JH, Amores A, Force A, Yan YL. 1999. The zebrafish genome. Methods Cell Biol 60:149-163.
30. Prakash L. 1994. The RAD6 gene and protein of Saccharomyces cerevisiae. Ann N Y Acad Sci 726:267-273.
31. Russell LB. 2004. Effects of male germ-cell stage on the frequency, nature, and spectrum of induced specific-locus mutations in the mouse. Genetica 122:25-36.
32. Russell LB, Matter B. 1980. Whole-mammal mutagenicity tests: Evaluation of five methods. Mutat Res 75:279-302.
33. Russell LB, Selby PB, Halle Ev, Sheridan W, Valcovic L. 1981. The mouse specific-locus test with agents other than radiations: Interpretation of data and recommendations for future work. Mutat Res 86:329-354.
34. Russell WL, Bangham JW, Russell LB. 1998. Differential response of mouse male germ-cell stages to radiation-induced specific-locus and dominant mutations. Genetics 148:1567-1578.
35. Shelby MD. 1994. Human germ cell mutagens. Environ Mol Mutagen 23(Suppl 24):30-34.
36. Shelby MD, Bishop JB, Mason JM, Tindall KR. 1993. Fertility, reproduction, and genetic disease: Studies on the mutagenic effects of environmental agents on mammalian germ cells. Environ Health Perspect 100:283-291.
37. Shima A, Shimada A. 1991. Development of a possible nonmammalian test system for radiation-induced germ-cell mutagenesis using a fish, the Japanese medaka, (Oryzias latipes). Proc Natl Acad Sci USA 88:2545-2549.
38. Shima A, Shimada A. 2001. The medaka as a models for studying germ-cell mutagenesis and genomic instability. Mar Biotechnol 3 (Suppl 1):S162-S167.
39. Shimada A, Shima A. 2001. High incidence of mosaic mutations induced by irradiating paternal germ cells of the medaka fish, Oryzias latipes. Mutat Res 495:33-42.
40. Shimada A, Shima A. 2004. Transgenerational genomic instability as revealed by a somatic mutation assay using the medaka fish. Mutat Res 552:33-42.
41. Shimada A, Eguchi H, Yoshinaga S, Shima A. 2005. Dose-rate effect on transgenerational mutation frequencies in spermatogonial stem cells of the medaka fish. Radiat Res 163:112-114.
42. 1 mice born to fathers irradiated at the spermatozoa stage. Radiat Res 157:661-667.
43. Singer TM, Lambert IB, Williams A, Douglas GR, Yauk CL. 2006. Detection of induced male germline mutation: Correlations and comparisons between traditional germline mutation assays, transgenic rodent assays and expanded simple tandem repeat instability assays. Mutat Res 598:164-193.
44. Strauss BS. 1991. The 'A rule' of mutagen specificity: A consequence of DNA polymerase bypass of non-instructional lesions? Bioessays 13:79-84.
45. Suzuki T, Itoh S, Takemoto N, Yajima N, Miura M, Hayashi M, Shimada H, Sofuni T. 1997. Ethyl nitrosourea and methyl methasulfonate mutagenicity in sperm and testicular germ cells of lacZ transgenic mice (Muta™Mouse). Mutat Res 388:155-163.
46. Vorobtsova IE. 2000. Irradiation of male rats increases the chromosomal sensitivity of progeny to genotoxic agents. Mutagen 15:33-38.
47. Vorobtsova IE, Aliyakparova LM, Anisimov VN. 1993. Promotion of skin tumors by 12-O-tetradecanoylphorbol-13-acetate in two generations of descendants of male mice exposed to X-ray irradiation. Mutat Res 287:207-216.
48. Walter RB, Rolig RL, Kozak KA, McEntire BB, Morizot DC, Nairn RS. 1993. Cloning and gene map assignment of the Xiphophorous DNA ligase 1 gene. Mol Biol Evol 10:1227-1238.
49. Watson DE, Cunningham ML, Tindall KR. 1998. Spontaneous and ENU-induced mutation spectra at the cll locus in Big Blue Rat2 embryonic firoblasts. Mutagen 13:487-497.
50. Winn RN. 2006. Mutagenesis: Insights from lambda-transgenic medaka. In: Evans DH, Claiborne JB, editors. The Physiology of Fishes, 3rd ed. Boca Raton: Taylor and Francis. pp 501-522.
51. Winn RN, Norris MB. 2005. Analysis of mutations in λ transgenic medaka using the cll mutation assay. In: Ostrander GK, editor. Techniques in Aquatic Toxicology, 2nd ed. New York: CRC Press. pp 705-734.
52. Winn RN, Van Beneden RJ, Burkhart JG. 1995. Transfer, methylation and spontaneous mutation frequency of φX174am3cs70 sequences in Medaka (Oryzias latipes) and Mummichog (Fundulus heteroclitus): Implications for gene transfer and environmental mutagenesis in aquatic species. Mar Environ Res 40:247-265.
53. Winn RN, Norris MB, Brayer KJ, Torres C, Muller SL. 2000. Detection of mutations in transgenic fish carrying a bacteriophage λ cll transgene target. Proc Natl Acad Sci 97:12655-12660.
54. Winn RN, Norris M, Muller S, Torres C, Brayer K. 2001. Bacteriophage λ and plasmid pUR288 transgenic fish models for detecting in vivo mutations. Mar Biotechnol 3:S185-S195.
55. Winn RN, Kling H, Norris MB. 2005a. Antimutagenicity of green tea polyphenols in the liver of transgenic medaka. Environ Mol Mutagen 46:88-95.
56. Winn RN, Norris MB, Turner J, Kimlin M. 2005b. Assessment of lambda transgenic fish as a new model of UV mutagenesis. Trans Ecol Environ 85:205-213.
57. Winn RN, Norris MB, Lothenbach D, Flynn K, Hammermeister D, Whiteman F, Sheedy B, Johnson R. 2006. Sub-chronic exposure to 1,1-dichloropropene induces frameshift mutations in lambda transgenic medaka. Mutat Res 595:52-59.
58. Wyrobek AJ, Mulvihill JJ, Wassom JS, Malling HV, Shelby MD, Lewis SE, Witt KL, Preston RJ, Perreault SD, Allen JW, Demarini DM, Woychik RP, Bishop JB. 2007. Assessing human germ-cell mutagen in the Postgenome Era: A celebration of the legacy of William Lawson (Bill) Russell. Environ Mol Mutagen 48:71-95.