Neonatal Vitamin B12 Deficiency Secondary to Maternal Subclinical Pernicious Anemia: Identification by Expanded Newborn Screening

Journal of Pediatrics

Volumn 152, Issue 5, 2008, Pages 731-733

  Marble, Michael ^a   Copeland, Sara ^b   Khanfar, Nashat ^c   Rosenblatt, David S ^d  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF IOWA CHILDREN S HOSPITAL   (United States)

^c Progressive Pediatrics   (United States)

^d MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLCARNITINE; CARNITINE; CYANOCOBALAMIN; HOMOCYSTEINE; HYDROXOCOBALAMIN; METHIONINE; METHYLMALONIC ACID; PROPIONYLCARNITINE; DRUG DERIVATIVE;

ARTICLE; CASE REPORT; CYANOCOBALAMIN DEFICIENCY; FEMALE; HUMAN; INFANT; NEWBORN; NEWBORN DISEASE; NEWBORN SCREENING; PERNICIOUS ANEMIA; PREGNANCY COMPLICATION; PREGNANCY OUTCOME; PRIORITY JOURNAL; URINALYSIS; VITAMIN BLOOD LEVEL; BLOOD; PREGNANCY;

ANEMIA, PERNICIOUS; CARNITINE; FEMALE; HUMANS; INFANT, NEWBORN; NEONATAL SCREENING; PREGNANCY; PREGNANCY COMPLICATIONS, HEMATOLOGIC; VITAMIN B 12 DEFICIENCY;

EID: 41849104490     PISSN: 00223476     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpeds.2008.01.023     Document Type: Article

References (13)

1. Rosenblatt D.S., and Whitehead V.M. Cobalamin and folate deficiency: acquired and hereditary disorders in children. Semin Hematol 36 (1999) 19-34
2. Naylor E.W., and Chase D.H. Automated tandem mass spectrometry for mass newborn screening for disorders in fatty acid, organic acid, and amino acid metabolism. J Child Neurol 14 Suppl 1 (1999) S4-S8
3. Dionisi-Vici C., Deodato F., Roschinger W., Rhead W., and Wilcken B. "Classical" organic acidurias, propionic aciduria, methylmalonic aciduria, and isovaleric aciduria: long-term outcome and effects of expanded newborn screening using tandem mass spectrometry. J Inherit Metab Dis 29 (2006) 383-389
4. Danielsson L., Enocksson E., Hagenfeldt L., Rasmussen E.B., and Tillberg E. Failure to thrive due to subclinical maternal pernicious anemia. Acta Paediatr Scand 77 (1988) 310-311
5. 12 deficiency. Eur J Pediatr 150 (1991) 205-208
6. 12 deficiency in an infant associated with a maternal deficiency and a strict vegetarian diet. J Pediatr Hematol Oncol 26 (2004) 270-271
7. 12 deficiency. Pediatr Crit Care Med 6 (2005) 483-485
8. Korenke G.C., Hunneman D.H., Eber S., and Hanefeld F. Severe encephalopathy with epilepsy in an infant caused by subclinical maternal pernicious anaemia: case report and review of the literature. Eur J Pediatr 163 (2004) 196-201
9. 12 deficiency: challenges in newborn screening for vitamin B12 deficiency. Haematologica 90 12 Suppl (2005) ECR 45
10. Wiley V., Carpenter K., and Wilcken B. Newborn screening with tandem mass spectrometry: 12 months experience in NSW Australia. Acta Paediatr Suppl 432 (1999) 48-51
11. Holleland G., Schneede J., Ueland P.M., Lund P.C., Refsum H., and Sandberg S. Cobalamin deficiency in general practice: assessment of the diagnostic utility and cost-benefit analysis of methylmalonic acid determination in relation to current diagnostic strategies. Clin Chem 45 (1999) 189-198
12. Andersson H.C., and Shapira E. Biochemical and clinical response to hydroxocobalamin versus cyanocobalamin treatment in patients with methylmalonic acidemia and homocystinuria (CblC). J Pediatr 132 (1998) 121-124
13. 12 deficiency. Clin Chem 48 (2002) 1126-1128