Endothelial cells and normal breast epithelial cells enhance invasion of breast carcinoma cells by CXCR-4-dependent up-regulation of urokinase-type plasminogen activator receptor (uPAR, CD87) expression

Journal of Pathology

Volumn 214, Issue 5, 2008, Pages 545-554

  Serrati S ^a   Margheri, F ^a   Fibbi, G ^a   Di Cara, G ^b   Minafra, L ^b   Pucci Minafra, I ^b   Liotta, F ^a   Annunziato, F ^a   Pucci D, M ^a   Del Rosso, M ^a,c  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF PALERMO   (Italy)

^c Department of Experimental Pathology and Oncology ^*  (Italy)

Author keywords

Angiogenesis; Breast cancer; CXCL12; CXCR4; Invasion; JNK; Microenvironment; SDF1; uPAR

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE KINASE 7; STRESS ACTIVATED PROTEIN KINASE; STROMAL CELL DERIVED FACTOR 1; UROKINASE;

ARTICLE; BREAST CANCER; BREAST EPITHELIUM; CANCER INVASION; CELL MIGRATION; CELL SURFACE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; GENE SEQUENCE; HUMAN; HUMAN CELL; METASTASIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; ZYMOGRAPHY;

BREAST; BREAST NEOPLASMS; CELL COMMUNICATION; CELL LINE; CHEMOKINE CXCL12; CULTURE MEDIA, CONDITIONED; ENDOTHELIUM, VASCULAR; EPITHELIAL CELLS; FEMALE; FIBRINOLYSIS; HUMANS; MAP KINASE KINASE 4; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; NEOVASCULARIZATION, PATHOLOGIC; PHOSPHORYLATION; RECEPTORS, CELL SURFACE; RECEPTORS, CXCR4; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 41849096039     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2309     Document Type: Article

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