Synthesis and characterization of DNA containing an N1-2′- deoxyinosine-ethyl-N3-thymidine interstrand cross-link: A structural mimic of the cross-link formed by 1,3-bis-(2-chloroethyl)-1-nitrosourea

Chemical Research in Toxicology

Volumn 21, Issue 3, 2008, Pages 686-695

  Wilds, Christopher J ^a   Xu, Fei ^a   Noronha, Anne M ^a  

^a Gina Cody School of Engineering and Computer Science   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

1 [N 1 (3' O TERT BUTYLDIMETHYLSILYL 5' O DIMETHOXYTRITYL 2' DEOXYINOSINYL)] 2 [N 3 (5' O DIMETHOXYTRITYLTHYMIDYL)] 3' O (BETA CYANOETHYL N,N' DIISOPROPYL)PHOSPHORAMIDITE ETHANE; 1 [N 1 (3' O TERT BUTYLDIMETHYLSILYL 5' O DIMETHOXYTRITYL 2' DEOXYINOSINYL)] 2 [N 3 (5' O DIMETHOXYTRITYLTHYMIDYL)] 3' O PHENOXYACETYL ETHANE; 1 [N 1 (3' O TERT BUTYLDIMETHYLSILYL 5' O DIMETHOXYTRITYL 2' DEOXYINOSINYL)] 2 [N 3 (5' O DIMETHOXYTRITYLTHYMIDYL)]ETHANE; 1 [N 1 (5' O DIMETHOXYTRITYL 2' DEOXYINOSINYL)] 2 [N 3 (5' O DIMETHOXYTRITYLTHYMIDYL)]ETHANE; 1 [N 1 (5' O DIMETHOXYTRITYL 2' DEOXYINOSINYL)] 3' O (BETA CYANOETHYL N,N' DIISOPROPYL)PHOSPHORAMIDITE] 2 [N 3 (5' O DIMETHOXYTRITYLTHYMIDYL)] 3' O (BETA CYANOETHYL N,N' DIISOPROPYL)PHOSPHORAMIDITE ETHANE; 5' O DIMETHOXYTRITYL 3' O TERT BUTYLDIMETHYLSILYL 2' DEOXYINOSINE; CARMUSTINE; DOUBLE STRANDED DNA; N 1 (2 CHLOROETHYL) 5' O DIMETHOXYTRITYL 3' O (TERT BUTYLDIMETHYLSILYL) 2' DEOXYINOSINE; N 1 (2 IODOETHYL) 5' O DIMETHOXYTRITYL 3' O (TERT BUTYLDIMETHYLSILYL) 2' DEOXYINOSINE; UNCLASSIFIED DRUG;

ARTICLE; CIRCULAR DICHROISM; CROSS LINKING; DENATURATION; DNA DAMAGE; DNA REPAIR; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTON NUCLEAR MAGNETIC RESONANCE; SOLID PHASE SYNTHESIS; ULTRAVIOLET RADIATION;

CARCINOGENS; CARMUSTINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; CROSS-LINKING REAGENTS; DNA; DNA REPAIR; INDICATORS AND REAGENTS; INOSINE; MODELS, MOLECULAR; NUCLEIC ACID DENATURATION; OLIGONUCLEOTIDES; THYMIDINE; ULTRAVIOLET RAYS;

EID: 41849094096     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx700422h     Document Type: Article

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