Synthesis of [1,2-3H]ethylamine hydrochloride and [ 3H]-labeled apadenoson for a human ADME study

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 51, Issue 2, 2008, Pages 113-117

  Hong, Yang ^a   Bonacorsi, Samuel J ^a   Tian, Yuan ^a   Gong, Sharon ^a   Zhang, Donglu ^a   Humphreys, W Griffith ^a   Balasubramanian, Balu ^a   Cheesman, Edward H ^b   Zhang, Zhiqin ^b   Castner, James F ^b   Crane, Paul D ^b  

^a BRISTOL MYERS SQUIBB RESEARCH AND DEVELOPMENT   (United States)

^b BRISTOL MYERS SQUIBB   (United States)

Author keywords

Adenosine A2a receptor agonist; Apadenoson; Tritium NMR (T NMR); 3H ethylamine hydrochloride

Indexed keywords

NUCLEAR MAGNETIC RESONANCE;

ADENOSINE A2A RECEPTOR AGONIST; APADENOSON; ETHYLAMINE; HIGH PURITY; RADIOCHEMICAL PURITY; STEP SEQUENCES; TRITIUM-NMR; [3H]ETHYLAMINE HYDROCHLORIDE;

TRITIUM;

ADENOSINE A2A RECEPTOR AGONIST; ETHYLAMINE; TRITIUM; UNCLASSIFIED DRUG; [1,2 3 H]ETHYLAMINE HYDROCHLORIDE; [3 H]APADENOSON;

ABSORPTION; ARTICLE; EXCRETION; FILTRATION; HUMAN; ISOTOPE LABELING; METABOLISM; RADIATION DOSE DISTRIBUTION; RADIOACTIVITY; RADIOCHEMISTRY; SEQUENCE ANALYSIS; SYNTHESIS;

EID: 41849088805     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.1495     Document Type: Article

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