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Volumn 71, Issue 1, 2008, Pages 132-138

HI-CHART: A Phase I/II Study on the Feasibility of High-Dose Continuous Hyperfractionated Accelerated Radiotherapy in Patients With Inoperable Non-Small-Cell Lung Cancer

Author keywords

Dose escalation; HI CHART; NSCLC; Phase I II; Radiotherapy

Indexed keywords

DOSIMETRY; ONCOLOGY; PATIENT MONITORING; PULMONARY DISEASES; RISK ANALYSIS; THREE DIMENSIONAL;

EID: 41749106933     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2007.09.048     Document Type: Article
Times cited : (41)

References (35)
  • 1
    • 0346236869 scopus 로고    scopus 로고
    • Long-term benefit is observed in a phase III comparison of sequential vs concurrent chemo-radiation for patients with unresected stage III nsclc: RTOG 9410
    • [Abstract]
    • Curran W., Scott C., Langer C., et al. Long-term benefit is observed in a phase III comparison of sequential vs concurrent chemo-radiation for patients with unresected stage III nsclc: RTOG 9410. [Abstract]. Proc ASCO (2003) 2499
    • (2003) Proc ASCO , pp. 2499
    • Curran, W.1    Scott, C.2    Langer, C.3
  • 2
    • 0032858243 scopus 로고    scopus 로고
    • Phase III study of concurrent versus sequential thoracic radiotherapy in combination with mitomycin, vindesine, and cisplatin in unresectable stage III non-small-cell lung cancer
    • Furuse K., Fukuoka M., Kawahara M., et al. Phase III study of concurrent versus sequential thoracic radiotherapy in combination with mitomycin, vindesine, and cisplatin in unresectable stage III non-small-cell lung cancer. J Clin Oncol 17 (1999) 2692-2699
    • (1999) J Clin Oncol , vol.17 , pp. 2692-2699
    • Furuse, K.1    Fukuoka, M.2    Kawahara, M.3
  • 3
    • 0033179899 scopus 로고    scopus 로고
    • Continuous, hyperfractionated, accelerated radiotherapy (CHART) versus conventional radiotherapy in non-small cell lung cancer: Mature data from the randomised multi-center trial
    • Saunders M.I., Dische S., Barrett A., et al. Continuous, hyperfractionated, accelerated radiotherapy (CHART) versus conventional radiotherapy in non-small cell lung cancer: Mature data from the randomised multi-center trial. Radiother Oncol 52 (1999) 137-148
    • (1999) Radiother Oncol , vol.52 , pp. 137-148
    • Saunders, M.I.1    Dische, S.2    Barrett, A.3
  • 4
    • 0033993435 scopus 로고    scopus 로고
    • Final results of phase III trial in regionally advanced unresectable non-small cell lung cancer: Radiation Therapy Oncology Group, Eastern Cooperative Oncology Group, and Southwest Oncology Group
    • Sause W., Kolesar P., Taylor S., et al. Final results of phase III trial in regionally advanced unresectable non-small cell lung cancer: Radiation Therapy Oncology Group, Eastern Cooperative Oncology Group, and Southwest Oncology Group. Chest 117 (2000) 358-364
    • (2000) Chest , vol.117 , pp. 358-364
    • Sause, W.1    Kolesar, P.2    Taylor, S.3
  • 5
    • 0033914570 scopus 로고    scopus 로고
    • Final report of the 70.2-Gy and 75.6-Gy dose levels of a phase I dose escalation study using three-dimensional conformal radiotherapy in the treatment of inoperable non-small cell lung cancer
    • Rosenzweig K.E., Mychalczak B., Fuks Z., et al. Final report of the 70.2-Gy and 75.6-Gy dose levels of a phase I dose escalation study using three-dimensional conformal radiotherapy in the treatment of inoperable non-small cell lung cancer. Cancer J 6 (2000) 82-87
    • (2000) Cancer J , vol.6 , pp. 82-87
    • Rosenzweig, K.E.1    Mychalczak, B.2    Fuks, Z.3
  • 6
    • 0035154254 scopus 로고    scopus 로고
    • Dose escalation in non-small-cell lung cancer using three-dimensional conformal radiation therapy update of a phase I trial
    • Hayman J.A., Martel M.K., Ten Haken R.K., et al. Dose escalation in non-small-cell lung cancer using three-dimensional conformal radiation therapy update of a phase I trial. J Clin Oncol 19 (2001) 127-136
    • (2001) J Clin Oncol , vol.19 , pp. 127-136
    • Hayman, J.A.1    Martel, M.K.2    Ten Haken, R.K.3
  • 7
    • 1542358175 scopus 로고    scopus 로고
    • Results following treatment to doses of 92.4 or 102.9 Gy on a phase I dose escalation study for non-small cell lung cancer
    • Narayan S., Henning G.T., Ten Haken R.K., et al. Results following treatment to doses of 92.4 or 102.9 Gy on a phase I dose escalation study for non-small cell lung cancer. Lung Cancer 44 (2004) 79-88
    • (2004) Lung Cancer , vol.44 , pp. 79-88
    • Narayan, S.1    Henning, G.T.2    Ten Haken, R.K.3
  • 8
    • 16544389343 scopus 로고    scopus 로고
    • Induction and concurrent chemotherapy with high-dose thoracic conformal radiation therapy in unresectable stage IIIA and IIIB non-small-cell lung cancer: A dose-escalation phase I trial
    • Socinski M.A., Morris D.E., Halle J.S., et al. Induction and concurrent chemotherapy with high-dose thoracic conformal radiation therapy in unresectable stage IIIA and IIIB non-small-cell lung cancer: A dose-escalation phase I trial. J Clin Oncol 22 (2004) 4341-4350
    • (2004) J Clin Oncol , vol.22 , pp. 4341-4350
    • Socinski, M.A.1    Morris, D.E.2    Halle, J.S.3
  • 9
    • 0036803119 scopus 로고    scopus 로고
    • High-dose conformal radiotherapy for treatment of stage IIIA/IIIB non-small-cell lung cancer: Technical issues and results of a phase I/II trial
    • Rosenman J.G., Halle J.S., Socinski M.A., et al. High-dose conformal radiotherapy for treatment of stage IIIA/IIIB non-small-cell lung cancer: Technical issues and results of a phase I/II trial. Int J Radiat Oncol Biol Phys 54 (2002) 348-356
    • (2002) Int J Radiat Oncol Biol Phys , vol.54 , pp. 348-356
    • Rosenman, J.G.1    Halle, J.S.2    Socinski, M.A.3
  • 10
    • 24944432301 scopus 로고    scopus 로고
    • High-dose radiation improved local tumor control and overall survival in patients with inoperable/unresectable non-small-cell lung cancer: Long-term results of a radiation dose escalation study
    • Kong F.M., Ten Haken R.K., Schipper M.J., et al. High-dose radiation improved local tumor control and overall survival in patients with inoperable/unresectable non-small-cell lung cancer: Long-term results of a radiation dose escalation study. Int J Radiat Oncol Biol Phys 63 (2005) 324-333
    • (2005) Int J Radiat Oncol Biol Phys , vol.63 , pp. 324-333
    • Kong, F.M.1    Ten Haken, R.K.2    Schipper, M.J.3
  • 11
    • 12844271279 scopus 로고    scopus 로고
    • Toxicity and outcome results of RTOG 9311: A phase I-II dose-escalation study using three-dimensional conformal radiotherapy in patients with inoperable non-small-cell lung carcinoma
    • Bradley J., Graham M.V., Winter K., et al. Toxicity and outcome results of RTOG 9311: A phase I-II dose-escalation study using three-dimensional conformal radiotherapy in patients with inoperable non-small-cell lung carcinoma. Int J Radiat Oncol Biol Phys 61 (2005) 318-328
    • (2005) Int J Radiat Oncol Biol Phys , vol.61 , pp. 318-328
    • Bradley, J.1    Graham, M.V.2    Winter, K.3
  • 12
    • 1942542250 scopus 로고    scopus 로고
    • Escalated dose for non-small-cell lung cancer with accelerated hypofractionated three-dimensional conformal radiation therapy
    • Thirion P., Holmberg O., Collins C.D., et al. Escalated dose for non-small-cell lung cancer with accelerated hypofractionated three-dimensional conformal radiation therapy. Radiother Oncol 71 (2004) 163-166
    • (2004) Radiother Oncol , vol.71 , pp. 163-166
    • Thirion, P.1    Holmberg, O.2    Collins, C.D.3
  • 13
    • 33746813139 scopus 로고    scopus 로고
    • Final results of a Phase I/II dose escalation trial in non-small-cell lung cancer using three-dimensional conformal radiotherapy
    • Belderbos J., Heemsbergen W., De Jaeger K., et al. Final results of a Phase I/II dose escalation trial in non-small-cell lung cancer using three-dimensional conformal radiotherapy. Int J Radiat Oncol Biol Phys 66 (2006) 126-134
    • (2006) Int J Radiat Oncol Biol Phys , vol.66 , pp. 126-134
    • Belderbos, J.1    Heemsbergen, W.2    De Jaeger, K.3
  • 14
    • 0031731368 scopus 로고    scopus 로고
    • Experience with dose escalation using CHARTWEL (continuous hyperfractionated accelerated radiotherapy week end less) in non-small cell lung cancer
    • Saunders M.I., Rojas A., Lyn B.E., et al. Experience with dose escalation using CHARTWEL (continuous hyperfractionated accelerated radiotherapy week end less) in non-small cell lung cancer. Br J Cancer 78 (1998) 1323-1328
    • (1998) Br J Cancer , vol.78 , pp. 1323-1328
    • Saunders, M.I.1    Rojas, A.2    Lyn, B.E.3
  • 15
    • 0036785960 scopus 로고    scopus 로고
    • Dose-escalation with CHARTWEL (continuous hyperfractionated accelerated radiotherapy week-end less) combined with neo-adjuvant chemotherapy in the treatment of locally advanced non-small cell lung cancer
    • Saunders M.I., Rojas A., Lyn B.E., et al. Dose-escalation with CHARTWEL (continuous hyperfractionated accelerated radiotherapy week-end less) combined with neo-adjuvant chemotherapy in the treatment of locally advanced non-small cell lung cancer. Clin Oncol 14 (2002) 352-360
    • (2002) Clin Oncol , vol.14 , pp. 352-360
    • Saunders, M.I.1    Rojas, A.2    Lyn, B.E.3
  • 16
    • 33749006218 scopus 로고    scopus 로고
    • Toxicity and outcome of a phase II trial of taxane-based neoadjuvant chemotherapy and 3-dimensional, conformal, accelerated radiotherapy in locally advanced nonsmall cell lung cancer
    • Rojas A.M., Lyn B.E., Wilson E.M., et al. Toxicity and outcome of a phase II trial of taxane-based neoadjuvant chemotherapy and 3-dimensional, conformal, accelerated radiotherapy in locally advanced nonsmall cell lung cancer. Cancer 107 (2006) 1321-1330
    • (2006) Cancer , vol.107 , pp. 1321-1330
    • Rojas, A.M.1    Lyn, B.E.2    Wilson, E.M.3
  • 17
    • 0036785983 scopus 로고    scopus 로고
    • From CHART to CHARTWEL in non-small cell lung cancer: Clinical radiobiological modelling of the expected change in outcome
    • Bentzen S.M., Saunders M.I., and Dische S. From CHART to CHARTWEL in non-small cell lung cancer: Clinical radiobiological modelling of the expected change in outcome. Clin Oncol (R Coll Radiol) 14 (2002) 372-381
    • (2002) Clin Oncol (R Coll Radiol) , vol.14 , pp. 372-381
    • Bentzen, S.M.1    Saunders, M.I.2    Dische, S.3
  • 18
    • 21244442951 scopus 로고    scopus 로고
    • Selective mediastinal node irradiation based on FDG-PET scan data in patients with non-small-cell lung cancer: A prospective clinical study
    • De Ruysscher D., Wanders S., van Haren E., et al. Selective mediastinal node irradiation based on FDG-PET scan data in patients with non-small-cell lung cancer: A prospective clinical study. Int J Radiat Oncol Biol Phys 62 (2005) 988-994
    • (2005) Int J Radiat Oncol Biol Phys , vol.62 , pp. 988-994
    • De Ruysscher, D.1    Wanders, S.2    van Haren, E.3
  • 19
    • 0031740895 scopus 로고    scopus 로고
    • FDG-PET scan in potentially operable non-small cell lung cancer: Do anatometabolic PET-CT fusion images improve the localisation of regional lymph node metastases?
    • Vansteenkiste J.F., Stroobants S.G., Dupont P.J., et al. FDG-PET scan in potentially operable non-small cell lung cancer: Do anatometabolic PET-CT fusion images improve the localisation of regional lymph node metastases?. Eur J Nucl Med 25 (1998) 1495-1501
    • (1998) Eur J Nucl Med , vol.25 , pp. 1495-1501
    • Vansteenkiste, J.F.1    Stroobants, S.G.2    Dupont, P.J.3
  • 23
    • 4544316279 scopus 로고    scopus 로고
    • Dose-volume effects in rat thoracolumbar spinal cord: An evaluation of NTCP models
    • Philippens M.E., Pop L.A., Visser A.G., et al. Dose-volume effects in rat thoracolumbar spinal cord: An evaluation of NTCP models. Int J Radiat Oncol Biol Phys 60 (2004) 578-590
    • (2004) Int J Radiat Oncol Biol Phys , vol.60 , pp. 578-590
    • Philippens, M.E.1    Pop, L.A.2    Visser, A.G.3
  • 24
    • 0032761213 scopus 로고    scopus 로고
    • Repair halftimes estimated from observations of treatment-related morbidity after CHART or conventional radiotherapy in head and neck cancer
    • Bentzen S.M., Saunders M.I., and Dische S. Repair halftimes estimated from observations of treatment-related morbidity after CHART or conventional radiotherapy in head and neck cancer. Radiother Oncol 53 (1999) 219-226
    • (1999) Radiother Oncol , vol.53 , pp. 219-226
    • Bentzen, S.M.1    Saunders, M.I.2    Dische, S.3
  • 25
    • 34047112709 scopus 로고    scopus 로고
    • Routine individualised patient dosimetry using electronic portal imaging devices
    • Nijsten S.M., Mijnheer B.J., Dekker A.L., et al. Routine individualised patient dosimetry using electronic portal imaging devices. Radiother Oncol 83 (2007) 65-75
    • (2007) Radiother Oncol , vol.83 , pp. 65-75
    • Nijsten, S.M.1    Mijnheer, B.J.2    Dekker, A.L.3
  • 26
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors
    • Therasse P., Arbuck S., Eisenhauer E., et al. New guidelines to evaluate the response to treatment in solid tumors. J Natl Cancer Inst 92 (2000) 205-216
    • (2000) J Natl Cancer Inst , vol.92 , pp. 205-216
    • Therasse, P.1    Arbuck, S.2    Eisenhauer, E.3
  • 27
    • 17144434501 scopus 로고
    • Endpoints for multi-modal clinical trials in stage III non-small cell lung cancer (NSCLC): A consensus report
    • Green M.R., Cox J.D., Ardizzoni A., et al. Endpoints for multi-modal clinical trials in stage III non-small cell lung cancer (NSCLC): A consensus report. Lung Cancer 11 (1994) S11-S13
    • (1994) Lung Cancer , vol.11
    • Green, M.R.1    Cox, J.D.2    Ardizzoni, A.3
  • 28
    • 0023677684 scopus 로고
    • International clinical trials in radiation oncology: The late effects of toxicity scoring
    • Rubin P., and Wasserman T.H. International clinical trials in radiation oncology: The late effects of toxicity scoring. Int J Radiat Oncol Biol Phys 114 (1988) S29-S38
    • (1988) Int J Radiat Oncol Biol Phys , vol.114
    • Rubin, P.1    Wasserman, T.H.2
  • 29
    • 0003307436 scopus 로고    scopus 로고
    • The linear-quadratic model in clinical practice
    • Steel G.G. (Ed), Arnold, London
    • Bentzen S.M., and Baumann M. The linear-quadratic model in clinical practice. In: Steel G.G. (Ed). Basic clinical radiobiology (2002), Arnold, London 134-146
    • (2002) Basic clinical radiobiology , pp. 134-146
    • Bentzen, S.M.1    Baumann, M.2
  • 30
    • 0036471281 scopus 로고    scopus 로고
    • Dose, volume, and tumor control prediction in primary radiotherapy of nonsmall-cell lung cancer
    • Willner J., Baier K., Caragiani E., et al. Dose, volume, and tumor control prediction in primary radiotherapy of nonsmall-cell lung cancer. Int J Radiat Oncol Biol Phys 52 (2002) 382-389
    • (2002) Int J Radiat Oncol Biol Phys , vol.52 , pp. 382-389
    • Willner, J.1    Baier, K.2    Caragiani, E.3
  • 31
    • 0035169875 scopus 로고    scopus 로고
    • A new approach to dose escalation in non-small-cell lung cancer
    • Mehta M., Scrimger R., Mackie R., et al. A new approach to dose escalation in non-small-cell lung cancer. Int J Radiat Oncol Biol Phys 49 (2001) 23-33
    • (2001) Int J Radiat Oncol Biol Phys , vol.49 , pp. 23-33
    • Mehta, M.1    Scrimger, R.2    Mackie, R.3
  • 32
    • 33644755371 scopus 로고    scopus 로고
    • Radiation-induced narrowing of the tracheobronchial tree: An in-depth analysis
    • Kelsey C.R., Kahn D., Hollis D.R., et al. Radiation-induced narrowing of the tracheobronchial tree: An in-depth analysis. Lung Cancer 52 (2006) 111-116
    • (2006) Lung Cancer , vol.52 , pp. 111-116
    • Kelsey, C.R.1    Kahn, D.2    Hollis, D.R.3
  • 33
    • 33947498981 scopus 로고    scopus 로고
    • Stereotactic body radiation therapy in multiple organ sites
    • Timmerman R.D., Kavanagh B.D., Cho L.C., et al. Stereotactic body radiation therapy in multiple organ sites. J Clin Oncol 25 (2007) 947-952
    • (2007) J Clin Oncol , vol.25 , pp. 947-952
    • Timmerman, R.D.1    Kavanagh, B.D.2    Cho, L.C.3
  • 34
    • 33748921880 scopus 로고    scopus 로고
    • Intra-patient variability of tumor volume and tumor motion during conventionally fractionated radiotherapy for locally advanced non-small-cell lung cancer: A prospective clinical study
    • Bosmans G., van Baardwijk A., Dekker A., et al. Intra-patient variability of tumor volume and tumor motion during conventionally fractionated radiotherapy for locally advanced non-small-cell lung cancer: A prospective clinical study. Int J Radiat Oncol Biol Phys 66 (2006) 748-753
    • (2006) Int J Radiat Oncol Biol Phys , vol.66 , pp. 748-753
    • Bosmans, G.1    van Baardwijk, A.2    Dekker, A.3
  • 35
    • 18944379885 scopus 로고    scopus 로고
    • Benefit of respiration-gated stereotactic radiotherapy for stage I lung cancer: An analysis of 4DCT datasets
    • Underberg R.W., Lagerwaard F.J., Slotman B.J., et al. Benefit of respiration-gated stereotactic radiotherapy for stage I lung cancer: An analysis of 4DCT datasets. Int J Radiat Oncol Biol Phys 62 (2005) 554-560
    • (2005) Int J Radiat Oncol Biol Phys , vol.62 , pp. 554-560
    • Underberg, R.W.1    Lagerwaard, F.J.2    Slotman, B.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.