Wnt signaling in retinal stem cells and regeneration

Development Growth and Differentiation

Volumn 50, Issue 4, 2008, Pages 245-251

  Kubo, Fumi ^a,b   Nakagawa, Shinichi ^a  

^a Japan Science and Technology Agency   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

Ciliary marginal zone; Regeneration; Retina; Stem cells; Wnt

Indexed keywords

BETA CATENIN; WNT PROTEIN;

CELL PROLIFERATION; CELL REGENERATION; CELL TYPE; CILIARY MARGINAL ZONE; EYE DEVELOPMENT; GLIA CELL; IN VIVO STUDY; MUELLER CELL; NONHUMAN; PIGMENT EPITHELIUM; RETINA CELL; REVIEW; STEM CELL; VERTEBRATE; XENOPUS; ANIMAL; CELL DIFFERENTIATION; CYTOLOGY; METABOLISM; PHYSIOLOGY; REGENERATION; RETINA; SIGNAL TRANSDUCTION;

VERTEBRATA;

ANIMALS; CELL DIFFERENTIATION; REGENERATION; RETINA; SIGNAL TRANSDUCTION; STEM CELLS; WNT PROTEINS;

EID: 41649094278     PISSN: 00121592     EISSN: 1440169X     Source Type: Journal    
DOI: 10.1111/j.1440-169X.2008.01033.x     Document Type: Review

References (58)

1. Ahmad, I., Tang, L. Pham, H. 2000. Identification of neural progenitors in the adult mammalian eye. Biochem. Biophys. Res. Commun 270, 517 521.
2. Amato, M. A., Arnault, E. Perron, M. 2004. Retinal stem cells in vertebrates: parallels and divergences. Int. J. Dev. Biol. 48, 993 1001.
3. Bergman, P. B., Moravski, C. J., Edmondson, S. R. et al. 2005. Expression of the IGF system in normal and diabetic transgenic (mRen-2), 27 rat eye. Invest. Ophthalmol. Vis. Sci. 46, 2708 2715.
4. Blanpain, C., Horsley, V. Fuchs, E. 2007. Epithelial stem cells: turning over new leaves. Cell 128, 445 458.
5. Boucher, S. E. Hitchcock, P. F. 1998. Insulin-related growth factors stimulate proliferation of retinal progenitors in the goldfish. J Comp Neurol 394, 386 394.
6. Cho, S. H. Cepko, C. L. 2006. Wnt2b/beta-catenin-mediated canonical Wnt signaling determines the peripheral fates of the chick eye. Development 133, 3167 3177.
7. Clevers, H. 2006. Wnt/beta-catenin signaling in development and disease. Cell 127, 469 480.
8. Close, J. L., Liu, J., Gumuscu, B. Reh, T. A. 2006. Epidermal growth factor receptor expression regulates proliferation in the postnatal rat retina. Glia 54, 94 104.
9. Coulombre, J. L. Coulombre, A. J. 1965. Regeneration of neural retina from the pigmented epithelium in the chick embryo. Dev. Biol. 12, 79 92.
10. Das, A. V., Zhao, X., James, J., Kim, M., Cowan, K. H. Ahmad, I. 2006. Neural stem cells in the adult ciliary epithelium express GFAP and are regulated by Wnt signaling. Biochem. Biophys. Res. Commun 339, 708 716.
11. Diaz, B., Serna, J., De Pablo, F. De La Rosa, E. J. 2000. In vivo regulation of cell death by embryonic (pro) insulin and the insulin receptor during early retinal neurogenesis. Development 127, 1641 1649.
12. Dorsky, R. I., Sheldahl, L. C. Moon, R. T. 2002. A transgenic Lef1/beta-catenin-dependent reporter is expressed in spatially restricted domains throughout zebrafish development. Dev. Biol. 241, 229 237.
13. Fischer, A. J., Dierks, B. D. Reh, T. A. 2002. Exogenous growth factors induce the production of ganglion cells at the retinal margin. Development 129, 2283 2291.
14. Fischer, A. J. Reh, T. A. 2000. Identification of a proliferating marginal zone of retinal progenitors in postnatal chickens. Dev. Biol. 220, 197 210.
15. Fischer, A. J. Reh, T. A. 2001. Muller glia are a potential source of neural regeneration in the postnatal chicken retina. Nat Neurosci 4, 247 252.
16. Fuhrmann, S., Stark, M. R. Heller, S. 2003. Expression of Frizzled genes in the developing chick eye. Gene. Expr. Patterns 3, 659 662.
17. Hackam, A. S. 2005. The Wnt signaling pathway in retinal degenerations. IUBMB Life 57, 381 388.
18. Harada, T., Harada, C., Nakayama, N. et al. 2000. Modification of glial-neuronal cell interactions prevents photoreceptor apoptosis during light-induced retinal degeneration. Neuron 26, 533 541.
19. Harris, W. A. Perron, M. 1998. Molecular recapitulation: the growth of the vertebrate retina. Int. J. Dev. Biol. 42, 299 304.
20. Hollyfield, J. G. 1968. Differential addition of cells to the retina in Rana pipiens tadpoles. Dev. Biol. 18, 163 179.
21. Hovanes, K., Li, T. W., Munguia, J. E. et al. 2001. Beta-catenin- sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer. Nat. Genet. 28, 53 57.
22. Inoue, T., Kagawa, T., Fukushima, M. et al. 2006. Activation of canonical Wnt pathway promotes proliferation of retinal stem cells derived from adult mouse ciliary margin. Stem Cells 24, 95 104.
23. Jasoni, C., Hendrickson, A. Roelink, H. 1999. Analysis of chicken Wnt-13 expression demonstrates coincidence with cell division in the developing eye and is consistent with a role in induction. Dev Dyn 215, 215 224.
24. Jin, E. J., Burrus, L. W. Erickson, C. A. 2002. The expression patterns of Wnts and their antagonists during avian eye development. Mech. Dev. 116, 173 176.
25. Kengaku, M., Capdevila, J., Rodriguez-Esteban, C. et al. 1998. Distinct WNT pathways regulating AER formation and dorsoventral polarity in the chick limb bud. Science 280, 1274 1277.
26. Kubo, F., Takeichi, M. Nakagawa, S. 2003. Wnt2b controls retinal cell differentiation at the ciliary marginal zone. Development 130, 587 598.
27. Kubo, F., Takeichi, M. Nakagawa, S. 2005. Wnt2b inhibits differentiation of retinal progenitor cells in the absence of Notch activity by downregulating the expression of proneural genes. Development 132, 2759 2770.
28. Kubota, R., Hokoc, J. N., Moshiri, A., Mcguire, C. Reh, T. A. 2002. A comparative study of neurogenesis in the retinal ciliary marginal zone of homeothermic vertebrates. Brain Res. Dev. Brain Res. 134, 31 41.
29. Liu, H., Mohamed, O., Dufort, D. Wallace, V. A. 2003. Characterization of Wnt signaling components and activation of the Wnt canonical pathway in the murine retina. Dev. Dyn. 227, 323 334.
30. Liu, H., Thurig, S., Mohamed, O., Dufort, D. Wallace, V. A. 2006. Mapping canonical Wnt signaling in the developing and adult retina. Invest. Ophthalmol. Vis. Sci. 47, 5088 5097.
31. Liu, H., Xu, S., Wang, Y. et al. 2007. Ciliary margin transdifferentiation from neural retina is controlled by canonical Wnt signaling. Dev. Biol. 308, 54 67.
32. Logan, C. Y. Nusse, R. 2004. The Wnt signaling pathway in development and disease. Annu. Rev. Cell Dev. Biol. 20, 781 810.
33. Morris, V. B., Wylie, C. C. Miles, V. J. 1976. The growth of the chick retina after hatching. Anat. Rec. 184, 111 113.
34. Moshiri, A., Close, J. Reh, T. A. 2004. Retinal stem cells and regeneration. Int J Dev Biol 48, 1003 1014.
35. Moshiri, A., Mcguire, C. R. Reh, T. A. 2005. Sonic hedgehog regulates proliferation of the retinal ciliary marginal zone in posthatch chicks. Dev. Dyn. 233, 66 75.
36. Moshiri, A. Reh, T. A. 2004. Persistent progenitors at the retinal margin of ptc mice. J. Neurosci. 24, 229 237.
37. Nakagawa, S., Takada, S., Takada, R. Takeichi, M. 2003. Identification of the laminar-inducing factor: Wnt-signal from the anterior rim induces correct laminar formation of the neural retina in vitro. Dev. Biol. 260, 414 425.
38. Ooto, S., Akagi, T., Kageyama, R. et al. 2004. Potential for neural regeneration after neurotoxic injury in the adult mammalian retina. Proc Natl Acad Sci U S A 101, 13654 13659.
39. Osakada, F., Ooto, S., Akagi, T., Mandai, M., Akaike, A. Takahashi, M. 2007. Wnt signaling promotes regeneration in the retina of adult mammals. J. Neurosci. 27, 4210 4219.
40. Otteson, D. C. Hitchcock, P. F. 2003. Stem cells in the teleost retina: persistent neurogenesis and injury-induced regeneration. Vision Res 43, 927 936.
41. Perron, M. Harris, W. A. 2000. Retinal stem cells in vertebrates. Bioessays 22, 685 688.
42. Perron, M., Kanekar, S., Vetter, M. L. Harris, W. A. 1998. The genetic sequence of retinal development in the ciliary margin of the Xenopus eye. Dev. Biol. 199, 185 200.
43. Reh, T. A. Levine, E. M. 1998. Multipotential stem cells and progenitors in the vertebrate retina. J. Neurobiol. 36, 206 220.
44. Reya, T. Clevers, H. 2005. Wnt signalling in stem cells and cancer. Nature 434, 843 850.
45. Sernagor, E. 2006. Retinal Development. Cambridge University Press, Cambridge.
46. Straznicky, K. Gaze, R. M. 1971. The growth of the retina in Xenopus laevis: an autoradiographic study. J. Embryol. Exp. Morph. 26, 67 79.
47. Sumanas, S. Ekker, S. C. 2001. Xenopus frizzled-5: a frizzled family member expressed exclusively in the neural retina of the developing eye. Mech. Dev. 103, 133 136.
48. Tropepe, V., Coles, B. L., Chiasson, B. J. et al. 2000. Retinal stem cells in the adult mammalian eye. Science 287, 2032 2036.
49. Van Es, J. H., Jay, P., Gregorieff, A. et al. 2005. Wnt signalling induces maturation of Paneth cells in intestinal crypts. Nat Cell Biol 7, 381 386.
50. Van Raay, T. J., Moore, K. B., Iordanova, I. et al. 2005. Frizzled 5 signaling governs the neural potential of progenitors in the developing Xenopus retina. Neuron 46, 23 36.
51. Wahlin, K. J., Campochiaro, P. A., Zack, D. J. Adler, R. 2000. Neurotrophic factors cause activation of intracellular signaling pathways in Muller cells and other cells of the inner retina, but not photoreceptors. Invest Ophthalmol Vis Sci 41, 927 936.
52. Wetts, R., Serbedzija, G. N. Fraser, S. E. 1989. Cell lineage analysis reveals multipotent precursors in the ciliary margin of the frog retina. Dev. Biol. 136, 254 263.
53. Yamaguchi, M., Tonou-Fujimori, N., Komori, A. et al. 2005. Histone deacetylase 1 regulates retinal neurogenesis in zebrafish by suppressing Wnt and Notch signaling pathways. Development 132, 3027 3043.
54. Yang, X. J. 2004. Roles of cell-extrinsic growth factors in vertebrate eye pattern formation and retinogenesis. Semin. Cell Dev. Biol. 15, 91 103.
55. Yi, H., Nakamura, R. E., Mohamed, O., Dufort, D. Hackam, A. S. 2007. Characterization of Wnt signaling during photoreceptor degeneration. Invest Ophthalmol Vis Sci 48, 5733 5741.
56. Zakin, L. D., Mazan, S., Maury, M., Martin, N., Guenet, J. L. Brulet, P. 1998. Structure and expression of Wnt13, a novel mouse Wnt2 related gene. Mech Dev 73, 107 116.
57. Zhao, S., Chen, Q., Hung, F. C. Overbeek, P. A. 2002. BMP signaling is required for development of the ciliary body. Development 129, 4435 4442.
58. Zhou, P., Byrne, C., Jacobs, J. Fuchs, E. 1995. Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate. Genes Dev 9, 700 713.