The quantitative and functional relation between insulin-like growth factor-I (IGF) and IGF-binding proteins during human osteoarthritis

Journal of Orthopaedic Research

Volumn 26, Issue 4, 2008, Pages 465-474

  Morales, Teresa I ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Human cartilage; IGF binding proteins (IGFBPs); IGF I analog; Insulin like growth factor I (IGF I); Osteoarthritis

Indexed keywords

PROTEOGLYCAN; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C; SULFATE;

ADULT; ARTICLE; CARTILAGE; FEMALE; HUMAN; HUMAN TISSUE; MALE; ORGAN CULTURE; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN METABOLISM; QUANTITATIVE ANALYSIS; ARTICULAR CARTILAGE; HIP OSTEOARTHRITIS; KNEE OSTEOARTHRITIS; METABOLISM; MIDDLE AGED; ORGAN CULTURE TECHNIQUE;

CARTILAGE, ARTICULAR; FEMALE; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; INSULIN-LIKE GROWTH FACTOR I; MALE; MIDDLE AGED; ORGAN CULTURE TECHNIQUES; OSTEOARTHRITIS, HIP; OSTEOARTHRITIS, KNEE;

EID: 41649090670     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1002/jor.20549     Document Type: Article

References (32)

1. Salmon WD Jr, Daughaday WH. 1957. A hormonally controlled serum factor, which stimulates sulfate incorporation by cartilage in vitro. J Lab Clin Invest 49:825-836.
2. McQuillan DJ, Handley CJ, Campbell MA, et al. 1986. Stimulation of proteoglycan biosynthesis by serum and insulin-like growth factor-I in cultured bovine articular cartilage. Biochem J 240:423-430.
3. Luyten FP, Hascall VC, Nissley SP, et al. 1988. Insulin-like growth factors maintain steady-state metabolism of proteoglycans in bovine articular cartilage explants. Arch Biochem Biophys 267:416-425.
4. Mankin HJ, Mow VC, Buckwalter JA. 2000. Articular cartilage repair and osteoarthritis. In: Buckwalter JA, Einhorn TA, Simon SR, editors. Orthopaedic basic science. Chicago: American Academy of Orthopaedic Surgeons; p 471-488.
5. Blakeley VA, Butler AA, Koval AP, et al. 1999. IGF-I receptor function. In: Rosenfeld R, Roberts C Jr, editors. Contemporary endocrinology: the IGF system. Totowa, NJ: Humana Press; p 143-163.
6. Nissley SP. 1999. Type II receptor mediated events. In: Rosenfeld R, Roberts C Jr, editors. Contemporary endocrinology: the IGF system. Totowa, NJ: Humana Press; p 165-197.
7. Firth SM, Baxter RC. 2002. Cellular actions of the insulinlike growth factor binding proteins. Endocr Rev 23:824-854.
8. Mohan S, Baylink DJ. 2002. IGF-binding proteins are multifunctional and act via IGF-dependent and-independent mechanisms. J Endocrinol 175:19-31.
9. Clemmons DR. 1999. IGF binding proteins and extracellular matrix. In: Rosenfeld R, Roberts C Jr, editors. Contemporary endocrinology: the IGF system. Totowa, NJ: Humana Press; p 273-279.
10. Youngman O, Rosenfeld RG. 1999. IGF-independent actions of the IGF binding proteins. In: Rosenfeld R, Roberts C Jr, editors. Contemporary endocrinology: the IGF system. Totowa, NJ: Humana Press; p 257-272.
11. Lee KW, Cohen P. 2002. Beyond carrier proteins. Nuclear effects: unexpected intracellular actions of insulin-like growth factor binding protein-3. J Endocrinol 175: 33-40.
12. Olney RC, Tsuchiya K, Wilson DM, et al. 1996. Chondrocytes from osteoarthritic cartilage have increased expression of insulin-like growth factor I (IGF-I) and IGF-binding protein-3 (IGFBP-3) and -5, but not IGF-II or IGFBP-4. J Clin Endocrinol Metab 81:1096-1103.
13. Tardif G, Roboul P, Pelletier J-P, et al. 1996. Normal expression of type 1 insulin-like growth factor receptor by human osteoarthritic chondrocytes with increased expression and synthesis of insulin-like growth factor binding proteins. Arthritis Rheum 39:968-978.
14. Chevalier X, Tyler JA. 1996. Production of binding proteins and role of the insulin-like growth factor I binding protein 3 in human articular cartilage explants. Br J Rheum 35:515-522.
15. Morales TI. 2002. The insulin-like growth factor binding proteins in uncultured human cartilage. Increases in insulin-like growth factor binding protein 3 during osteoarthritis. Arthritis Rheum 46:2358-2367.
16. Eviatar T, Kauffman H, Maroudas A. 2003. Synthesis of insulin-like binding protein 3 in vitro in human articular cartilage cultures. Arthritis Rheum 48:410-417.
17. Verschure PJ, Van Marle J, Joosten LAB, et al. 1996. Localization of insulin-like growth factor-1 receptor in human normal and osteoarthritic cartilage in relation to proteoglycan synthesis and content. Br J Rheum 35:1044-1055.
18. Dore S, Abribat T, Rousseau N, et al. 1995. Increased insulin-like growth factor 1 production by human osteoarthritic chondrocytes is not dependent on growth hormone action. Arthritis Rheum 38:413-419.
19. Schneiderman R, Rosenberg N, Hiss J, et al. 1995. Concentration and size distribution of insulin-like growth factor-I in human normal and osteoarthritic synovial fluid and cartilage. Arch Biochem Biophys 324:173-188.
20. Mankin HJ, Dorfman HD, Lippiello L, et al. 1971. Biochemical and metabolic abnormalities in articular cartilage from osteoarthritic human hips: II. Correlation of morphology with biochemical and metabolic data. J Bone Joint Surg 53A:523-537.
21. Farndale RW, Buttle DJ, Barret AJ. 1988. Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue. Biochim Biophys Acta 883:173-177.
22. Ballard FJ, Wallace JC, Francis GL, et al. 1996. Des (1-3) IGF-I: a truncated form of insulin-like growth factor-I. Int J Biochem Cell Biol 28:1085-1087.
23. Oh Y, Muller HL, Lee D-Y, et al. 1993. Characterization of the affinities of insulin-like growth factor (IGF)-binding proteins 1-4for IGF-I, IGF-II, IGF-I/insulin hybrid, and IGF-I analogs. Endocrinology 132:1337-1343.
24. Francis GL, Aplin SE, Milner SJ, et al. 1993. Insulin-like growth factor (IGF)-II binding to IGF-binding proteins and IGF receptors is modified by deletion of the N-terminal hexapeptide or substitution of arginine for glutamate-6 in IGF-II. Biochem J 293:713-719.
25. Clemmons DR, Dehoff ML, Busby WH, et al. 1992. Competition for binding to insulin-like growth factor (IGF) binding protein-2, 3, 4,and 5 by the IGFs and IGF analogs. Endocrinology 131:890-895.
26. Morales TI. 1997. The role and content of endogenous insulin-like growth factor-binding proteins in bovine articular cartilage. Arch Biochem Biophys 343:164-172.
27. Bhakta NR, Garcia AM, Frank EH, et al. 2000. The insulin-like growth factors (IGFs) I and II bind to articular cartilage via the IGF-binding proteins. J Biol Chem 275: 5860-5866.
28. Hunziker EB, Kapfinger E, Martin JA, et al. 2007. The Insulin-like growth factor binding protein-3 (IGFBP-3) is closely associated with the chondrocyte nucleus in human articular cartilage. OA Cartilage.
29. DeCeuninck F, Caliez A, Dassencourt L, Anract P, et al. 2004. Pharmacological disruption of insulin-like growth factor 1 binding to IGF-binding proteins restores anabolic responses in human osteoarthritic chondrocytes. Arthritis Res Ther 6:R393-R403.
30. Martin JA, Ellerbroek SM, Buckwalter J. 1997. Age-related decline in chondrocyte response to insulin-like growth factor-I: the role of growth factor binding proteins. J Orthop Res 15:491-498.
31. Loeser RF, Shanker G, Carlson CS, et al. 2000. Reduction in the chondrocyte response to insulin-like growth factor 1 in aging and osteoarthritis. Arthritis Rheum 43:2110-2120.
32. DeGroot J, Verzijl N, Bank RA, et al. 1999. Age-related decrease in proteoglycan synthesis of human articular chondrocytes. Arth & Rheum 42:1003-1009.