Elevated serum erythropoietin concentration is associated with coordinated changes in red blood cell and reticulocyte indices of pregnant women at term

Scandinavian Journal of Clinical and Laboratory Investigation

Volumn 68, Issue 2, 2008, Pages 160-165

  Ervasti, M ^a   Kotisaari, S ^a   Heinonen, S ^a   Punnonen, K ^a  

^a KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

Erythropoietin; Iron deficiency; Pregnancy; Red blood cell; Reticulocyte

Indexed keywords

ERYTHROPOIETIN; FERRITIN; HEMOGLOBIN; IRON; TRANSFERRIN RECEPTOR;

ADULT; ARTICLE; CORRELATION ANALYSIS; ERYTHROCYTE; ERYTHROPOIESIS; FEMALE; HEMOGLOBIN DETERMINATION; HUMAN; IRON DEFICIENCY; MULTIVARIATE ANALYSIS; NORMAL HUMAN; PREDICTION; PREGNANCY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; REGRESSION ANALYSIS; RETICULOCYTE;

ERYTHROCYTES; ERYTHROPOIETIN; FEMALE; HUMANS; PREGNANCY; PREGNANCY TRIMESTER, THIRD; RETICULOCYTES;

EID: 41649089013     PISSN: 00365513     EISSN: 15027686     Source Type: Journal    
DOI: 10.1080/00365510701550102     Document Type: Article

References (22)

1. Jelkmann W. Erythropoietin: structure, control of production, and function. Physiol Rev 1992;72:449-89.
2. Huch R, Huch A. Erythropoietin in obstetrics. Hematol Oncol Clin North Am 1994;8:1021-40.
3. Jelkmann W. Molecular biology of erythropoietin. Intern Med 2004;43:649-59.
4. Beguin Y, Lipscei G, Thoumsin H, Fillet G. Blunted erythropoietin production and decreased erythropoiesis in early pregnancy. Blood 1991;78:89-93.
5. Riikonen S, Saijonmaa O, Järvenpää A-L, Fyhrquist F. Serum concentrations of erythropoietin in healthy and anaemic pregnant women. Scand J Clin Lab Invest 1994;54:653-7.
6. McMullin MF, White R, Lappin T, Reeves J, MacKenzie G. Haemoglobin during pregnancy: relationship to erythropoietin and haematinic status. Eur J Haematol 2003;71:44-50.
7. Milman N, Graudal N, Nielsen OJ, Agger AO. Serum erythropoietin during normal pregnancy: relationship to hemoglobin and iron status markers and impact of iron supplementation in a longitudinal, placebo-controlled study on 118 women. Int J Hematol 1997;66:159-68.
8. Goldstein JD, Garry DJ, Maulik D. Obstetric conditions and erythropoietin levels. Am J Obstet Gynecol 2000;182:1055-7.
9. Widness JA, Schmidt RL, Sawyer ST. Erythropoietin transplacental passage. Review of animal studies. J Perinat Med 1995;23:61-70.
10. Kotisaari S, Romppanen J, Penttilä I, Punnonen K. The Advia 120 red blood cell and reticulocyte indices are useful in diagnosis of iron-deficiency anemia. Eur J Haematol 2002;68:150-6.
11. Brugnara C. Iron deficiency and erythropoiesis: new diagnostic approaches. Clin Chem 2003;49:1573-8.
12. Schaefer R, Schaefer L. Hypochromic red blood cells and reticulocytes. Kidney Int 1999;55:S44-8.
13. Brugnara C, Zurakowski D, DiCanzio J, Boyd T, Platt O. Reticulocyte hemoglobin content to diagnose iron deficiency in children. J Am Med Assoc 1999;281:2225-30.
14. Ullrich C, Wu A, Armsby C, Rieber S, Wingerter S, Brugnara C, et al. Screening healthy infants for iron deficiency using reticulocyte hemoglobin content. J Am Med Assoc 2005;294:924-30.
15. Stoffman N, Brugnara C, Woods ER. An algorithm using reticulocyte hemoglobin content (CHr) measurement in screening adolescent for iron deficiency. J Adolesc Health 2005;36:529.e1-6.
16. Breymann C. Iron deficiency and anaemia in pregnancy: modern aspects of diagnosis and therapy. Blood Cells Mol Dis 2002;29:506-16.
17. Krafft A, Huch R, Breymann C. Impact of parturition on iron status in nonanaemic iron deficiency. Eur J Clin Invest 2003;33:919-23.
18. Suominen P, Punnonen K, Rajamaki A, Irjala K. Evaluation of new immunoenzymometric assay for measuring soluble transferrin receptor to detect iron deficiency in anemic patients. Clin Chem 1997;43:1641-6.
19. WHO. Standards for maternal and neonatal care: iron and folate supplementation. Integrated management of pregnancy and childbirth (IMPAC). IMPAC; 2006.
20. Kotisaari S, Romppanen J, Ågren U, Eskelinen S, Punnonen K. Reticulocyte indices rapidly reflect an increase in iron availability for erythropoiesis. Haematologica 2003;88:1422-3.
21. Punnonen K, Irjala K, Rajamäki A. Serum transferrin receptor and its ratio to serum ferritin in the diagnosis of iron deficiency. Blood 1997;89:1052-7.
22. Thomas C, Thomas L. Biochemical markers and hematologic indices in the diagnosis of functional iron deficiency. Clin Chem 2002;48:1066-76.