Rational screening of antibodies and design of sandwich enzyme linked immunosorbant assay on the basis of a kinetic model

Journal of Bioscience and Bioengineering

Volumn 105, Issue 3, 2008, Pages 261-272

  Choi, Dong Hwan ^a   Katakura, Yoshio ^a   Ninomiya, Kazuaki ^a   Shioya, Suteaki ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

association rate constant; dissociation rate constant; kinetic model; phage antibody; sandwich enzyme linked immunosorbant assay; simulation

Indexed keywords

ANTIGEN-ANTIBODY REACTIONS; IMMUNOSENSORS; MONOCLONAL ANTIBODIES; PROTEINS; RATE CONSTANTS; REACTION KINETICS;

ASSOCIATION RATE CONSTANTS; DISSOCIATION RATE CONSTANTS; KINETIC MODELS; SANDWICH ENZYME LINKED IMMUNOSORBANT ASSAY;

ENZYME ACTIVITY;

ANTIBODY; C REACTIVE PROTEIN;

ANTIBODY LIBRARY; ANTIBODY SCREENING; ANTIGEN ANTIBODY REACTION; ARTICLE; CONTROLLED STUDY; DISSOCIATION CONSTANT; ENZYME LINKED IMMUNOSORBENT ASSAY; HYBRIDOMA; KINETICS; NONHUMAN;

AMINO ACID SEQUENCE; ANTIBODIES; ANTIGEN-ANTIBODY REACTIONS; C-REACTIVE PROTEIN; COMPUTER SIMULATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; KINETICS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY;

EID: 41549163214     PISSN: 13891723     EISSN: None     Source Type: Journal    
DOI: 10.1263/jbb.105.261     Document Type: Article

References (27)

1. Malmsten M. Ellipsometry of protein layers adsorbed at hydrophobic surfaces. J. Colloid Interface Sci. 166 (1994) 333-342
2. Bulter J.E., Ni L., Nessler R., Joshi K.S., Suter M., Rosenberg B., Chang J., Brown W.R., and Cantarero L.A. The physical and functional behavior of capture antibodies adsorbed on polystyrene. J. Immunol. Methods 150 (1992) 77-90
3. Zhuang G., Katakura Y., Furuta T., Omasa T., Kishimoto M., and Suga K. A kinetic model for a biopanning process considering antigen desorption and effective antigen concentration on a solid phase. J. Biosci. Bioeng. 91 (2001) 474-481
4. Lomax D.P., Roubal W.T., Moore J.D., and Johnson L.L. An enzyme-linked immunosorbent assay (ELISA) for measuring vitellogenin in English sole (Pleuronectes vetulus): development, validation and cross-reactivity with other pleuronectids. Comp. Biochem. Physiol. B Biochem. Mol. Biol. 121 (1998) 425-436
5. Lemaire S., Dumont M., and Nolet S. Sensitive method of detection, quantitation, and purification of peptides using pre-column derivatization with phenyl isothiocyanate. J. Chromatogr. 425 (1988) 77-86
6. Griffiths A.D., and Duncan A.R. Strategies for selection of antibodies by phase display. Curr. Opin. Biotechnol. 9 (1998) 102-108
7. Holt L.J., Enever C., Wildt R.M., and Tomlinson I.M. The use of recombinant antibodies in proteomic. Curr. Opin. Biotechnol. 11 (2000) 445-449
8. Fjeld J.G., and Skretting A. Evaluation of labeled monoclonal antibodies by simultaneous estimation of the association constant, the immunoreactive fraction, and the number of effective binding sites on the specific target. J. Immunol. Methods 151 (1992) 97-106
9. Katakura Y., Zhuang G., Nakatani T., Furuta T., Omasa T., Kishimoto M., Suga K., and Shioya S. A practical kinetic model for efficient isolation of useful antibodies from phage display libraries. J. Mol. Catal. B: Enzym. 29 (2004) 191-200
10. Zhuang G., Katakura Y., Omasa T., Kishimoto M., and Suga K. Measurementof association rate constant of antibody-antigen interaction in solution based on enzyme-linked immunosorbent assay. J. Biosci. Bioeng. 92 (2001) 330-336
11. Hardy F., Djavadi-Ohaniance L., and Goldberg M.E. Measurement of antibody/antigen association rate constants in solution by a method based on the enzyme-linked immunosorbent assay. J. Immunol. Methods 200 (1997) 155-159
12. Hoylaerts M.F., Bollen A., and De Broe M.E. The application of enzyme kinetics to the determination of dissociation constants for antigen-antibody interactions in solution. J. Immunol. Methods 126 (1990) 253-261
13. 9 transformants from 1 microgram of vector DNA. Nihon Univ. J. Med. 47 (2005) 43-56
14. Nader R., Russell P.T., and Paul M.R. Clinical efficacy of an automated high-sensitivity C-reactive protein assay. Clin. Chem. 45 (1999) 2136-2141
15. Jiang H., Lint T.F., and Gewurz H. Defined chemically cross-linked oligomers of human C-reactive protein: characterization and reactivity with the complement system. Immunology 74 (1991) 725-731
16. John E.V. Human C-reactive protein: expression, structure, and function. Mol. Immunol. 38 (2001) 189-197
17. Tsumoto K., Shinoki K., Kondo H., Uchikawa M., Juji T., and Kumagai I. Highly efficient recovery of functional single-chain Fv fragments from inclusion bodies overexpressed in Escherichia coli by controlled introduction of oxidizing reagen-application to a human single-chain Fv fragment. J. Immnol. Methods 219 (1998) 119-129
18. Piran U., and Riordan W.R. Dissociation rate constant of the biotin-streptavidin complex. J. Immunol. Methods 133 (1990) 141-143
19. Lancet D., Sadovsky E., and Seidemann E. Probability model for molecular recognition in biological receptor repertoires: significance to the olfactory system. Proc. Natl. Acad. Sci. USA 90 (1993) 3715-3719
20. Goldbaum F.A., Cauerhff A., Velikovsky C.A., Llera A.S., Riottot M.M., and Poljak R.J. Lack of significant differences in association rates and affinities of antibodies from short-term and long-term responses to hen egg lysozyme. J. Immunol. 162 (1999) 6040-6045
21. Foote J., and Eisen H.N. Kinetic and affinity limits on antibodies produced during immune responses. Proc. Natl. Acad. Sci. USA 92 (1995) 1254-1256
22. Volanakis J.E. Human C-reactive protein: expression, structure, and function. Mol. Immunol. 38 (2001) 189-197
23. Potempa L.A., Siegel J.N., Fiedel B.A., Potempa R.T., and Gewurz H. Expression, detection and assay of a neoantigen (neo-CRP) associatied with a free, human C-reactive protein subunit. Mol. Immnol. 24 (1987) 513-531
24. Bass S., Greene R., and Wells J.A. Hormone phage: an enrichment method for variant proteins with altered binding properties. Proteins 8 (1990) 309-314
25. Bradbury A., Persic L., Werge T., and Cattaneo A. Use of living columns to select specific phage antibodies. Biotechnology 11 (1993) 1565-1569
26. Gill S.C., and von Hippel P.H. Calculation of protein extinction coefficients from amino acid sequence data. Anal. Biochem. 182 (1989) 319-326
27. Huang S.C., Stump M.D., Weiss R., and Caldwell K.D. Binding of biotinylated DNA to streptavidin-coated polystyrene latex: effects of chain length and particle size. Anal. Biochem. 237 (1996) 115-122