Downregulation of hepatic lipoprotein assembly in rats by fermented products of Monascus pilosus

Nutrition

Volumn 24, Issue 5, 2008, Pages 477-483

  Kuo, Chia Feng ^a   Jao, Yueh Chuan ^a   Yang, Ping ^a  

^a SHIH CHIEN UNIVERSITY   (Taiwan)

Author keywords

Acyl coenzyme A:cholesterol acyltransferase; Apolipoprotein B 100; Garlic; Microsomal triacylglycerol transfer protein; Monascus pilosus

Indexed keywords

3 HYDROXY 3 METHYLGLUTARYL COENZYME A; ACYL COENZYME A; APOLIPOPROTEIN B100; CHOLESTEROL ACYLTRANSFERASE; GARLIC EXTRACT; LIPOPROTEIN; MYCELIA EXTRACT; PROBIOTIC AGENT; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CHOLESTEROL DIET; CONTROLLED STUDY; DOWN REGULATION; FERMENTED PRODUCT; GARLIC; HYPERCHOLESTEROLEMIA; LIPID BLOOD LEVEL; MALE; MONASCUS; MONASCUS PILOSUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; UPREGULATION;

ANIMALS; ANTICHOLESTEREMIC AGENTS; CHOLESTEROL, DIETARY; DOWN-REGULATION; FERMENTATION; GARLIC; HYPERCHOLESTEROLEMIA; LIPOPROTEINS; LIVER; MALE; MONASCUS; OXIDATION-REDUCTION; PHYTOTHERAPY; PLANT EXTRACTS; RANDOM ALLOCATION; RATS;

ALLIUM SATIVUM; ANIMALIA; MONASCUS; MONASCUS PILOSUS; RATTUS; RATTUS NORVEGICUS;

EID: 41549147215     PISSN: 08999007     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nut.2008.01.011     Document Type: Article

References (41)

1. Steinberg D., Parthasarathy S., Carew T.E., Khoo J.C., and Witztum J.L. Beyond cholesterol, modifications of low-density lipoprotein that increase its atherogenicity. N Engl J Med 320 (1989) 915-924
2. Holvoet P. Oxidized LDL and coronary heart disease. Acta Cardiol 59 (2004) 479-484
3. Carew T.E., Schwenke D.C., and Steinberg D. Antiatherogenic effect of probucol unrelated to its hypercholesterolemic effect: evidence that antioxidant in vivo can selectively inhibit low density lipoprotein degradation in macrophage-rich fatty streaks and slow the progression of atherosclerosis in the Watanabe Heritable hyperlipidemic rabbit. Proc Natl Acad Sci USA 84 (1987) 7725-7729
4. Kita T., Nagano Y., Yokode M., Ishi K., Kume N., Ooshima A., et al. Probucol prevents the progression of atherosclerosis in Watanabe Heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia. Proc Natl Acad Sci USA 84 (1987) 5928-5932
5. Juzlova P., Martinkova L., and Kren V. Secondary metabolites of the fungus Monascus: a review. J Ind Microbiol 16 (1996) 163-170
6. Martinkova L., Juzlova P., and Vesely D. Biological activity of polyketide pigments produced by the fungus Monascus. J Appl Bact 19 (1995) 609-616
7. Endo A. Chemistry, biochemistry, and pharmacology of HMG-CoA reductase inhibitors. Klin Wochenschr 66 (1988) 421-427
8. Junxian W., Lu Z., Chi J., Wang W., Su M., Kou W., et al. Multicenter clinical trial of the serum lipid-lowering effects of a Monascus purpureus (red yeast) rice preparation from traditional Chinese medicine. Curr Ther Res 58 (1997) 964-978
9. Mangaloglu L., Cheung R.C., Van Iderstine S.C., Taghibiglou C., Pontrelli L., and Adeli K. Treatment with atorvastatin ameliorates hepatic very-low-density lipoprotein overproduction in an animal model of insulin resistance, the fructose-fed Syrian golden hamster: evidence that reduced hypertriglyceridemia is accompanied by improved hepatic insulin sensitivity. Metabolism 51 (2002) 409-418
10. Wang I.K., Chen P.C., and Lin J.K. Hypotriglyceridemic effect of anka (a fermentated rice product of Monascus spp.) in rats. J Agric Food Chem 48 (2000) 3183-3189
11. Aniya Y., Yokomakura T., Yonamine M., Shimada K., Nagamine T., Shimabukuro M., et al. Screening of antioxidant action of various molds and protection of Monascus anka against experimentally induced liver injuries of rats. Gen Pharmacol 32 (1999) 225-231
12. Kuo C.-F., Wang T.-S., Yang P.-L., Jao Y.-C., and Lin W.-Y. Antioxidant activity of liquid-state fermentation products of Monascus pilosus grown in garlic-containing medium. J Food Sci 71 (2006) 456-460
13. Folch J., Lee M., and Sloane S.G.H. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226 (1957) 497-509
14. Wetterau J.R., Lin M.C.M., and Jamli H. Microsomal triglyceride transfer protein. Biochim Biophys Acta 1345 (1997) 136-150
15. Chang T.Y., Chang C.C., Ohgami N., and Yamauchi Y. Cholesterol sensing, trafficking, and esterification. Annu Rev Cell Dev Biol 22 (2006) 129-157
16. Yeh Y.-Y., and Yeh S.M. Garlic reduces plasma lipids by inhibiting hepatic cholesterol and triacylglycerol synthesis. Lipids 29 (1994) 189-193
17. Eilat S., Oestraicher S., Rabinkov S., Ohad D., Mirelman D., Battler A., et al. Alteration of lipid profile in hyperlipidemic rabbit by allicin, an active constituent of garlic. Coron Artery Dis 6 (1995) 985-990
18. Chan L. Apolipoprotein B, the major protein component of triglyceride rich and low density lipoprotein. J Biol Chem 267 (1992) 25621-25624
19. Yao Z., and McLeod R.S. Synthesis and secretion of hepatic apolipoprotein B-containing lipoproteins. Biochim Biophys Acta 1212 (1994) 152-166
20. Sniderman A.D., and Cianflone K. Substrate delivery as a determinant of hepatic apoB secretion. Arterioscler Thromb 13 (1993) 629-636
21. Thompson G.R., Naoumova R.P., and Watts G.F. Role of cholesterol in regulating apolipoprotein B secretion by the liver. J Lipid Res 37 (1996) 439-447
22. Olekers P., Behari A., Cromley D., Billheimer J.T., and Sturley S.L. Characterization of two human genes encoding acyl coenzyme A-cholesterol acyltransferase related enzymes. J Biol Chem 273 (1998) 26765-26778
23. Van Greevenbroek M.M., Robertus-Teunissen M.G., Erkelens D.W., and de Bruin T.W. Participation of the microsomal triglyceride transfer protein in lipoprotein assembly in Caco-2 cells: interaction with saturated and unsaturated dietary fatty acids. J Lipid Res 39 (1993) 173-185
24. Shelness G.S., Ingram M.F., Huang X.F., and DeLozier J.A. Apolipoprotein B in the rough endoplasmic reticulum: translation, translocation and the initiation of lipoprotein assembly. J Nutr 129 (1999) 456-462
25. Brown M.S., and Goldstein J.L. A receptor-mediated pathway for cholesterol homeostasis. Science 232 (1986) 34-47
26. Chang T.Y., Chang C.C., Ohgami N., and Yamauchi Y. Cholesterol sensing, trafficking, and esterification. Annu Rev Cell Dev Biol 22 (2006) 129-157
27. Björkhem I., and Akerlund J.E. Studies on the link between HMG-CoA reductase and cholesterol 7α-hydroxylase in rat liver. J Lipid Res 29 (1988) 136-143
28. Liu L., and Yeh Y.Y. S-alk(en)yl cysteines of garlic inhibit cholesterol synthesis by deactivating HMG-CoA reductase in cultured rat hepatocytes. J Nutr 132 (2002) 1129-1134
29. Gordon D.A., Hamil H., Gregg R.E., Olofsson S.-O., and Boren J. Inhibition of the microsomal triglyceride transfer protein blocks the first step of apolipoprotein B lipoprotein assembly but not the addition of bulk core lipids in the second step. J Biol Chem 271 (1996) 33047-33053
30. Jamil H., Gordon D.A., Eustice D.C., Brooks C.M., Dickson K.J.K., Chen Y., et al. An inhibitor of the microsomal triglyceride transfer protein inhibits apoB secretion from HepG2 cells. Proc Natl Acad Sci USA 93 (1996) 11991-11995
31. Wetterau J.R., Gregg R.E., Harrity T.W., Arbeeny C., Cap M., Connolly F., et al. An MTP inhibitor that normalizes atherogenic lipoprotein levels in WHHL rabbits. Science 282 (1998) 751-754
32. Cuchel M., Bloedon L.T., Szapary P.O., Kolansky D.M., Wolfe M.L., Sarkis A., et al. Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia. N Engl J Med 356 (2007) 148-156
33. Pal S., Ho N., Santos C., Dubois P., Mamo J., Croft K., et al. Red wine polyphenolics increase LDL receptor expression and activity and suppress the secretion of apoB100 from human HepG2 cells. J Nutr 133 (2003) 700-706
34. Nerurkar P.V., Pearson L., Efird J.T., Adeli K., Theriault A.G., and Nerurkar V.R. Microsomal triglyceride transfer protein gene expression and apo B secretion are inhibited by bitter melon in HepG2 cells. J Nutr 135 (2005) 702-706
35. Wilcox L.J., Borradaile N.M., Dreu L.E., and Huff M.W. Secretion of hepatocyte apo B is inhibited by the flavonoids, naringenin and hesperetin, via reduced activity and expression of ACAT2 and MTP. J Lipid Res 42 (2001) 725-734
36. Huff M.W., Telford D.E., Barrett P.H.R., Billheimer J.T., and Gillies P.J. Inhibition of hepatic ACAT decreases apoB secretion in miniature pigs fed a cholesterol-free diet. Arterioscler Thromb 14 (1994) 1498-1508
37. Ramharack R., Spahr M.A., and Sekerke C.S. CI-1011 lowers lipoprotein and plasma cholesterol concentrations in chow-fed cynomolgus monkeys. Atherosclerosis 136 (1998) 79-87
38. Nicolosi R.J., Wilson T.A., and Krause B.R. The ACAT inhibitor, CI-1011 is effective in the prevention and regression of aortic fatty streak area in hamsters. Atherosclerosis 137 (1998) 77-85
39. Fridovich I. Superoxide dismutases. An adaptation to a paramagnetic gas. J Biol Chem 264 (1989) 7761-7764
40. Michiels C., Raes M., Toussaint O., and Remacle H. Importance of Se-glutathione peroxidase, catalase, and Cu/Zn-SOD for cell survival against oxidative stress. Free Radic Biol Med 17 (1994) 235-248
41. Maldonado P.D., Barrera D., Medina-Campos O.N., Hernandez-Pando R., Ibarra-Rubio M.E., and Pedraza-Chaverri J. Aged garlic extract attenuates gentamicin induced renal damage and oxidative stress in rats. Life Sci 73 (2003) 2543-2556