메뉴 건너뛰기




Volumn 4, Issue 1, 2008, Pages 109-116

Trabectedin and its potential in the treatment of soft tissue sarcoma

Author keywords

Chemotherapy; DNA repair; Drug development; Sarcoma

Indexed keywords

BRCA1 PROTEIN; CAPECITABINE; CISPLATIN; DEXAMETHASONE; DOCETAXEL; DOXORUBICIN; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; IFOSFAMIDE; IMATINIB; PACLITAXEL; RNA BINDING PROTEIN; SEROTONIN 3 ANTAGONIST; STEROID; TRABECTEDIN;

EID: 41549138731     PISSN: 11766336     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (27)

References (44)
  • 1
    • 0027280571 scopus 로고
    • An intergroup phase III randomized study of doxorubicin and dacarbazine with or without ifosfamide and mesna in advanced soft tissue and bone sarcomas
    • Antman K, Crowley J, Balcerzak SP, et al. 1993. An intergroup phase III randomized study of doxorubicin and dacarbazine with or without ifosfamide and mesna in advanced soft tissue and bone sarcomas. J Clin Oncol, 11:1276-85.
    • (1993) J Clin Oncol , vol.11 , pp. 1276-1285
    • Antman, K.1    Crowley, J.2    Balcerzak, S.P.3
  • 2
    • 0035675835 scopus 로고    scopus 로고
    • Prognostic impact of P53 status, TLS-CHOP fusion transcript structure, and histological grade in myxoid liposarcoma: A molecular and clinicopathologic study of 82 cases
    • Antonescu CR, Tschernyavsky SJ, Decuseara R, et al. 2001. Prognostic impact of P53 status, TLS-CHOP fusion transcript structure, and histological grade in myxoid liposarcoma: a molecular and clinicopathologic study of 82 cases. Clin Cancer Res, 7:3977-87.
    • (2001) Clin Cancer Res , vol.7 , pp. 3977-3987
    • Antonescu, C.R.1    Tschernyavsky, S.J.2    Decuseara, R.3
  • 3
    • 33745444832 scopus 로고    scopus 로고
    • Docetaxel and gemcitabine combination in 133 advanced soft-tissue sarcomas: A retrospective analysis
    • Bay JO, Ray-Coquard I, Fayette J, et al. 2006. Docetaxel and gemcitabine combination in 133 advanced soft-tissue sarcomas: a retrospective analysis. Int J Cancer, 119:706-11.
    • (2006) Int J Cancer , vol.119 , pp. 706-711
    • Bay, J.O.1    Ray-Coquard, I.2    Fayette, J.3
  • 4
    • 2942571277 scopus 로고    scopus 로고
    • A phase II study of ET-743/trabectedin ('Yondelis') for patients with advanced gastrointestinal stromal tumours
    • Blay JY, Le CA, Verweij J, Scurr M, et al. (2004). A phase II study of ET-743/trabectedin ('Yondelis') for patients with advanced gastrointestinal stromal tumours. Eur J Cancer, 40:1327-31.
    • (2004) Eur J Cancer , vol.40 , pp. 1327-1331
    • Blay1    JY, L.C.2    Verweij, J.3    Scurr, M.4
  • 5
    • 23844442937 scopus 로고    scopus 로고
    • Soft-tissue sarcomas in adults
    • Clark MA, Fisher C, Judson I, et al. 2005. Soft-tissue sarcomas in adults. N Engl J Med, 353:701-11.
    • (2005) N Engl J Med , vol.353 , pp. 701-711
    • Clark, M.A.1    Fisher, C.2    Judson, I.3
  • 6
    • 53149097453 scopus 로고    scopus 로고
    • Final results of a combination study between trabectedin and pegylated
    • Cohen RB, Schilder RJ, Cheng J, et al. 2005. Final results of a combination study between trabectedin and pegylated. ASCO Meeting Abstracts, 23:3074.
    • (2005) ASCO Meeting Abstracts , vol.23 , pp. 3074
    • Cohen, R.B.1    Schilder, R.J.2    Cheng, J.3
  • 7
    • 0027227651 scopus 로고
    • Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma
    • Crozat A, Aman P, Mandahl N, et al. 1993. Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma. Nature, 363:640-4.
    • (1993) Nature , vol.363 , pp. 640-644
    • Crozat, A.1    Aman, P.2    Mandahl, N.3
  • 8
    • 0142089888 scopus 로고    scopus 로고
    • The combination of yondelis and cisplatin is synergistic against human tumor xenografts
    • D'Incalci M, Colombo T, Ubezio P, et al. 2003. The combination of yondelis and cisplatin is synergistic against human tumor xenografts. Eur J Cancer, 39:1920-6.
    • (2003) Eur J Cancer , vol.39 , pp. 1920-1926
    • D'Incalci, M.1    Colombo, T.2    Ubezio, P.3
  • 9
    • 27744452788 scopus 로고    scopus 로고
    • DNA and non-DNA targets in the mechanism of action of the antitumor drug trabectedin
    • David-Cordonnier MK Gajate C, Olmea O, et al. 2005. DNA and non-DNA targets in the mechanism of action of the antitumor drug trabectedin. Chem Biol, 12:1201-10.
    • (2005) Chem Biol , vol.12 , pp. 1201-1210
    • David-Cordonnier, M.K.1    Gajate, C.2    Olmea, O.3
  • 10
    • 0035281734 scopus 로고    scopus 로고
    • Ecteinascidin-743: A marine-derived compound in advanced, pretreated sarcoma patients - preliminary evidence of activity
    • Delaloge S, Yovine A, Taamma A, et al. 2001. Ecteinascidin-743: a marine-derived compound in advanced, pretreated sarcoma patients - preliminary evidence of activity. J Clin Oncol, 19:1248-55.
    • (2001) J Clin Oncol , vol.19 , pp. 1248-1255
    • Delaloge, S.1    Yovine, A.2    Taamma, A.3
  • 11
    • 0141731283 scopus 로고    scopus 로고
    • Complete protection by high-dose dexamethasone against the hepatotoxicity ofthe novel antitumor drug yondelis (ET-743) in the rat
    • Donald S, Verschoyle RD, Greaves P, et al. 2003. Complete protection by high-dose dexamethasone against the hepatotoxicity ofthe novel antitumor drug yondelis (ET-743) in the rat. Cancer Res, 63:5902-8.
    • (2003) Cancer Res , vol.63 , pp. 5902-5908
    • Donald, S.1    Verschoyle, R.D.2    Greaves, P.3
  • 12
    • 0027256397 scopus 로고
    • Randomized comparison of doxorubicin alone versus ifosfamide plus doxorubicin or mitomycin, doxorubicin, and cisplatin against advanced soft tissue sarcomas
    • Edmonson JH, Ryan LM, Blum RH, et al. 1993. Randomized comparison of doxorubicin alone versus ifosfamide plus doxorubicin or mitomycin, doxorubicin, and cisplatin against advanced soft tissue sarcomas. J Clin Oncol, 11:1269-75.
    • (1993) J Clin Oncol , vol.11 , pp. 1269-1275
    • Edmonson, J.H.1    Ryan, L.M.2    Blum, R.H.3
  • 13
    • 0037096739 scopus 로고    scopus 로고
    • Ecteinascidin-743 inhibits activated but not constitutive transcription
    • Friedman D, Hu Z, Kolb EA, et al. 2002. Ecteinascidin-743 inhibits activated but not constitutive transcription. Cancer Res, 62:3377-81.
    • (2002) Cancer Res , vol.62 , pp. 3377-3381
    • Friedman, D.1    Hu, Z.2    Kolb, E.A.3
  • 14
    • 24944460785 scopus 로고    scopus 로고
    • Ecteinascidin-743 (ET-743) for chemotherapy-naive patients with advanced soft tissue sarcomas: Multicenter phase II and pharmacokinetic study
    • Garcia-Carbonero R, Supko JG, Maki RG, et al. 2005. Ecteinascidin-743 (ET-743) for chemotherapy-naive patients with advanced soft tissue sarcomas: multicenter phase II and pharmacokinetic study. J Clin Oncol, 23:5484-92.
    • (2005) J Clin Oncol , vol.23 , pp. 5484-5492
    • Garcia-Carbonero, R.1    Supko, J.G.2    Maki, R.G.3
  • 15
    • 2342461682 scopus 로고    scopus 로고
    • Phase II and pharmacokinetic study of ecteinascidin 743 in patients with progressive sarcomas of soft tissues refractory to chemotherapy
    • Garcia-Carbonero R, Supko JG, Manola J, et al. 2004. Phase II and pharmacokinetic study of ecteinascidin 743 in patients with progressive sarcomas of soft tissues refractory to chemotherapy. J Clin Oncol, 22:1480-90.
    • (2004) J Clin Oncol , vol.22 , pp. 1480-1490
    • Garcia-Carbonero, R.1    Supko, J.G.2    Manola, J.3
  • 16
    • 0000183433 scopus 로고    scopus 로고
    • Identification of biochemical parameters that predict the onset of severe toxicities in patients treated with ET-743
    • Gomez J, Lopez-Lazaro L, Guzman C, et al. 2000. Identification of biochemical parameters that predict the onset of severe toxicities in patients treated with ET-743. ASCO Meeting Abstracts, 19:727.
    • (2000) ASCO Meeting Abstracts , vol.19 , pp. 727
    • Gomez, J.1    Lopez-Lazaro, L.2    Guzman, C.3
  • 17
    • 41549144621 scopus 로고    scopus 로고
    • Phase I combination study of trabectedin (T) and capecitabine (C) in patients with advanced malignancies
    • Gore L, Rivera E, Lavallee K, et al. 2006. Phase I combination study of trabectedin (T) and capecitabine (C) in patients with advanced malignancies. ASCO Meeting Abstracts, 24:2079.
    • (2006) ASCO Meeting Abstracts , vol.24 , pp. 2079
    • Gore, L.1    Rivera, E.2    Lavallee, K.3
  • 18
    • 0242650889 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic (PK) study of ecteinascidin-743 (ET, Trabectedin) and cisplatin (P) combination in pre-treated patients (pts) with selected advanced solid tumors
    • Grasselli G, Malossi A, Colombo N, et al. 2007. Phase I and pharmacokinetic (PK) study of ecteinascidin-743 (ET, Trabectedin) and cisplatin (P) combination in pre-treated patients (pts) with selected advanced solid tumors. ASCO Meeting Abstracts, 22:542.
    • (2007) ASCO Meeting Abstracts , vol.22 , pp. 542
    • Grasselli, G.1    Malossi, A.2    Colombo, N.3
  • 19
    • 33747447825 scopus 로고    scopus 로고
    • Patterns of tumor response to trabectedin (ET743) in myxoid liposarcomas
    • Grosso F, Demetri GD, Blay JY, et al. 2006. Patterns of tumor response to trabectedin (ET743) in myxoid liposarcomas. ASCO Meeting Abstracts, 24:9511.
    • (2006) ASCO Meeting Abstracts , vol.24 , pp. 9511
    • Grosso, F.1    Demetri, G.D.2    Blay, J.Y.3
  • 20
    • 33745161449 scopus 로고    scopus 로고
    • Steroid premedication markedly reduces liver and bone marrow toxicity of trabectedin in advanced sarcoma
    • Grosso F, Dileo P, Sanfilippo R, et al. 2006. Steroid premedication markedly reduces liver and bone marrow toxicity of trabectedin in advanced sarcoma. Eur J Cancer, 42:1484-90.
    • (2006) Eur J Cancer , vol.42 , pp. 1484-1490
    • Grosso, F.1    Dileo, P.2    Sanfilippo, R.3
  • 21
    • 50349083290 scopus 로고    scopus 로고
    • Sensitivity of myxoid-round cell liposarcoma (MRCL) to trabectedin (T) may be related to a direct effect on the fusion transcript
    • Grosso F, Forni C, Frapolli R, et al. 2007). Sensitivity of myxoid-round cell liposarcoma (MRCL) to trabectedin (T) may be related to a direct effect on the fusion transcript. ASCO Meeting Abstracts, 25: 10000.
    • (2007) ASCO Meeting Abstracts , vol.25 , pp. 10000
    • Grosso, F.1    Forni, C.2    Frapolli, R.3
  • 22
    • 34347214071 scopus 로고    scopus 로고
    • Efficacy of trabectedin (ecteinascidin-743) in advanced pretreated myxoid liposarcomas: A retrospective study
    • Grosso F, Jones RL, Demetri GD, et al. 2007. Efficacy of trabectedin (ecteinascidin-743) in advanced pretreated myxoid liposarcomas: a retrospective study. Lancet Oncol, 8:595-602.
    • (2007) Lancet Oncol , vol.8 , pp. 595-602
    • Grosso, F.1    Jones, R.L.2    Demetri, G.D.3
  • 23
    • 0037096747 scopus 로고    scopus 로고
    • Gemcitabine and docetaxel in patients with unresectable leiomyosarcoma: Results of a phase II trial
    • Hensley ML, Maki R, Venkatraman E, et al. 2002. Gemcitabine and docetaxel in patients with unresectable leiomyosarcoma: results of a phase II trial. J Clin Oncol, 20:2824-31.
    • (2002) J Clin Oncol , vol.20 , pp. 2824-2831
    • Hensley, M.L.1    Maki, R.2    Venkatraman, E.3
  • 24
    • 33748035692 scopus 로고    scopus 로고
    • Cross-talk between nucleotide excision and homologous recombination DNA repair pathways in the mechanism of action of antitumor trabectedin
    • Herrero AB, Martin-Castellanos C, Marco E, et al. 2006. Cross-talk between nucleotide excision and homologous recombination DNA repair pathways in the mechanism of action of antitumor trabectedin. Cancer Res, 66:8155-62.
    • (2006) Cancer Res , vol.66 , pp. 8155-8162
    • Herrero, A.B.1    Martin-Castellanos, C.2    Marco, E.3
  • 25
    • 33947149579 scopus 로고    scopus 로고
    • Ecteinascidin-743: Evidence of activity in advanced, pretreated soft tissue and bone sarcoma patients
    • Huygh G, Clement PM, Dumez H, et al. 2006. Ecteinascidin-743: evidence of activity in advanced, pretreated soft tissue and bone sarcoma patients. Sarcoma, 2006:56282.
    • (2006) Sarcoma , vol.2006 , pp. 56282
    • Huygh, G.1    Clement, P.M.2    Dumez, H.3
  • 26
    • 20044372153 scopus 로고    scopus 로고
    • Phase II study of ET-743 in advanced soft tissue sarcomas: A European Organisation for the Research and Treatment of Cancer (EORTC) soft tissue and bone sarcoma group trial
    • Blay JY, Judson I, et al. 2005, Phase II study of ET-743 in advanced soft tissue sarcomas: a European Organisation for the Research and Treatment of Cancer (EORTC) soft tissue and bone sarcoma group trial. J Clin Oncol, 23:576-84.
    • (2005) J Clin Oncol , vol.23 , pp. 576-584
    • Blay, J.Y.1    Judson, I.2
  • 27
    • 41549089846 scopus 로고    scopus 로고
    • Randomized phase II study of trabectedin in patients with liposarcoma and leiomyosarcoma (L-sarcomas) after failure of prior anthracylines (A) and ifosfamide (I)
    • Morgan JA, Le Cesne A, Chawla S, et al. 2007. Randomized phase II study of trabectedin in patients with liposarcoma and leiomyosarcoma (L-sarcomas) after failure of prior anthracylines (A) and ifosfamide (I). ASCO Meeting Abstracts, 25:10060.
    • (2007) ASCO Meeting Abstracts , vol.25 , pp. 10060
    • Morgan, J.A.1    Le Cesne, A.2    Chawla, S.3
  • 28
    • 41549123853 scopus 로고    scopus 로고
    • Phase I and pharmacokinetics (PK) study of sequential paclitaxel and trabectedin every 2 weeks in patients with advanced solid tumors
    • Papadopoulos KP, Chu Q, Patnaik A, et al. 2006. Phase I and pharmacokinetics (PK) study of sequential paclitaxel and trabectedin every 2 weeks in patients with advanced solid tumors. ASCO Meeting Abstracts, 24:2029.
    • (2006) ASCO Meeting Abstracts , vol.24 , pp. 2029
    • Papadopoulos, K.P.1    Chu, Q.2    Patnaik, A.3
  • 29
    • 0035424877 scopus 로고    scopus 로고
    • Phase II clinical investigation of gemcitabine in advanced soft tissue sarcomas and window evaluation of dose rate on gemcitabine triphosphate accumulation
    • Patel SR, Gandhi V, Jenkins J, et al. 2001. Phase II clinical investigation of gemcitabine in advanced soft tissue sarcomas and window evaluation of dose rate on gemcitabine triphosphate accumulation.. J Clin Oncol, 19:3493-9.
    • (2001) J Clin Oncol , vol.19 , pp. 3493-3499
    • Patel, S.R.1    Gandhi, V.2    Jenkins, J.3
  • 30
    • 0036913513 scopus 로고    scopus 로고
    • A phase II and pharmacokinetic study of ecteinascidin 743 in patients with gastrointestinal stromal tumors
    • Ryan DP, Puchalski T, Supko JG, et al. 2002. A phase II and pharmacokinetic study of ecteinascidin 743 in patients with gastrointestinal stromal tumors. Oncologist, 7:531-8.
    • (2002) Oncologist , vol.7 , pp. 531-538
    • Ryan, D.P.1    Puchalski, T.2    Supko, J.G.3
  • 31
    • 0035127175 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of ecteinascidin 743 administered as a 72-hour continuous intravenous infusion in patients with solid malignancies
    • Ryan DP, Supko JG, Eder JP, et al. 2001. Phase I and pharmacokinetic study of ecteinascidin 743 administered as a 72-hour continuous intravenous infusion in patients with solid malignancies. Clin Cancer Res, 7:231-42.
    • (2001) Clin Cancer Res , vol.7 , pp. 231-242
    • Ryan, D.P.1    Supko, J.G.2    Eder, J.P.3
  • 32
    • 4043125603 scopus 로고    scopus 로고
    • Randomized phase II study of trabectedin (ET-743) given by two
    • Samuels BL, Rushing D, Chawla SP, et al. 2004. Randomized phase II study of trabectedin (ET-743) given by two. ASCO Meeting Abstracts, 22:9000.
    • (2004) ASCO Meeting Abstracts , vol.22 , pp. 9000
    • Samuels, B.L.1    Rushing, D.2    Chawla, S.P.3
  • 33
    • 41549100818 scopus 로고    scopus 로고
    • DNA repair functionality modulates the clinical outcome of patients
    • Schoffski P, Casali PG, Taron M, et al. 2006. DNA repair functionality modulates the clinical outcome of patients. ASCO Meeting Abstracts, 24:9522.
    • (2006) ASCO Meeting Abstracts , vol.24 , pp. 9522
    • Schoffski, P.1    Casali, P.G.2    Taron, M.3
  • 34
    • 34548706418 scopus 로고    scopus 로고
    • From the cover: Replication and homologous recombination repair regulate DNA double-strand break formation by the antitumor alkylator ecteinascidin 743
    • Soares DG, Escargueil AE, Poindessous V, et al. 2007. From the cover: replication and homologous recombination repair regulate DNA double-strand break formation by the antitumor alkylator ecteinascidin 743. Proc Natl Acad Sci USA, 104:13062-7.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 13062-13067
    • Soares, D.G.1    Escargueil, A.E.2    Poindessous, V.3
  • 35
    • 0035281641 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of ecteinascidin-743, a new marine compound, administered as a 24-hour continuous infusion in patients with solid tumors
    • Taamma A, Misset JL, Riofrio M, et al. 2001. Phase I and pharmacokinetic study of ecteinascidin-743, a new marine compound, administered as a 24-hour continuous infusion in patients with solid tumors. J Clin Oncol, 19:1256-65.
    • (2001) J Clin Oncol , vol.19 , pp. 1256-1265
    • Taamma, A.1    Misset, J.L.2    Riofrio, M.3
  • 36
    • 0036894384 scopus 로고    scopus 로고
    • Sequence-dependent synergistic cytotoxicity of ecteinascidin-743 and paclitaxel in human breast cancer cell lines in vitro and in vivo
    • Takahashi N, Li W, Banerjee D, et al. 2002. Sequence-dependent synergistic cytotoxicity of ecteinascidin-743 and paclitaxel in human breast cancer cell lines in vitro and in vivo. Cancer Res, 62:6909-15.
    • (2002) Cancer Res , vol.62 , pp. 6909-6915
    • Takahashi, N.1    Li, W.2    Banerjee, D.3
  • 37
    • 0034786774 scopus 로고    scopus 로고
    • Sequence-dependent enhancement of cytotoxicity produced by ecteinascidin 743 (ET-743) with doxorubicin or paclitaxel in soft tissue sarcoma cells
    • Takahashi N, Li WW, Banerjee D, et al. 2001. Sequence-dependent enhancement of cytotoxicity produced by ecteinascidin 743 (ET-743) with doxorubicin or paclitaxel in soft tissue sarcoma cells. Clin Cancer Res, 7:3251-7.
    • (2001) Clin Cancer Res , vol.7 , pp. 3251-3257
    • Takahashi, N.1    Li, W.W.2    Banerjee, D.3
  • 38
    • 0035136529 scopus 로고    scopus 로고
    • Ecteinascidin 743 induces protein-linked. DNA breaks in human colon carcinoma HCT116 cells and is cytotoxic independently of topoisomerase I expression
    • Takebayashi Y, Goldwasser F, Urasaki Y, et al. 2001. Ecteinascidin 743 induces protein-linked. DNA breaks in human colon carcinoma HCT116 cells and is cytotoxic independently of topoisomerase I expression. Clin Cancer Res, 7:185-91.
    • (2001) Clin Cancer Res , vol.7 , pp. 185-191
    • Takebayashi, Y.1    Goldwasser, F.2    Urasaki, Y.3
  • 39
    • 17944374027 scopus 로고    scopus 로고
    • Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair
    • Takebayashi Y, Pourquier P, Zimonjic DB, et al. 2001. Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair. Nat Med, 7:961-66.
    • (2001) Nat Med , vol.7 , pp. 961-966
    • Takebayashi, Y.1    Pourquier, P.2    Zimonjic, D.B.3
  • 40
    • 0142121506 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of Yondelis (Ecteinascidin-743; ET-743) administered as an infusion over 1 h or 3 h every 21 days in patients with solid tumours
    • Twelves C, Hoekman K, Bowman A, et al. 2003. Phase I and pharmacokinetic study of Yondelis (Ecteinascidin-743; ET-743) administered as an infusion over 1 h or 3 h every 21 days in patients with solid tumours. Eur J Cancer, 39:1842-51.
    • (2003) Eur J Cancer , vol.39 , pp. 1842-1851
    • Twelves, C.1    Hoekman, K.2    Bowman, A.3
  • 41
    • 0036154945 scopus 로고    scopus 로고
    • A phase I and pharmacokinetic study of ecteinascidin-743 on a daily x 5 schedule in patients with solid malignancies
    • Villalona-Calero MA, Eckhardt SG, Weiss G, et al. 2002. A phase I and pharmacokinetic study of ecteinascidin-743 on a daily x 5 schedule in patients with solid malignancies. Clin Cancer Res, 8:75-85.
    • (2002) Clin Cancer Res , vol.8 , pp. 75-85
    • Villalona-Calero, M.A.1    Eckhardt, S.G.2    Weiss, G.3
  • 42
    • 41549106488 scopus 로고    scopus 로고
    • Phase I study of trabectedin (T) in combination with docetaxel (D) in patients with advanced malignancies
    • Von Mehren M, Buck D, Temmer E, et al. 2006. Phase I study of trabectedin (T) in combination with docetaxel (D) in patients with advanced malignancies. ASCO Meeting Abstracts, 24:2068.
    • (2006) ASCO Meeting Abstracts , vol.24 , pp. 2068
    • Von Mehren, M.1    Buck, D.2    Temmer, E.3
  • 43
    • 84944374895 scopus 로고
    • Doxorubicin chemotherapy in the treatment of soft-tissue sarcoma. Combined results of two randomized trials
    • Wilson RE, Wood WC, Lerner HL, et al. 1986. Doxorubicin chemotherapy in the treatment of soft-tissue sarcoma. Combined results of two randomized trials. Arch Surg, 121:1354-9.
    • (1986) Arch Surg , vol.121 , pp. 1354-1359
    • Wilson, R.E.1    Wood, W.C.2    Lerner, H.L.3
  • 44
    • 1542398698 scopus 로고    scopus 로고
    • Phase II study of ecteinascidin-743 in advanced pretreated soft tissue sarcoma patients
    • Yovine A, Riofrio M, Blay JY, et al. 2004. Phase II study of ecteinascidin-743 in advanced pretreated soft tissue sarcoma patients. J Clin Oncol, 22:890-9.
    • (2004) J Clin Oncol , vol.22 , pp. 890-899
    • Yovine, A.1    Riofrio, M.2    Blay, J.Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.