Muscle dystrophy single point mutation in the 2B segment of lamin A does not affect the mechanical properties at the dimer level

Journal of Biomechanics

Volumn 41, Issue 6, 2008, Pages 1295-1301

  Zhang, Huanan ^a   Ackbarow, Theodor ^a   Buehler, Markus J ^a  

^a Massachusetts Institute of Technology   (United States)

Author keywords

Deformation; Fracture; Lamin; Laminopathy; Mechanical properties; Muscle dystrophy; Nanomechanics; Nuclear envelope; Plasticity; Stress strain; Young's modulus

Indexed keywords

CELLS; DIMERS; MECHANICAL PROPERTIES; MUTAGENESIS; NANOMECHANICS; PROTEINS;

LAMINOPATHY; MUSCLE DYSTROPHY; NUCLEAR ENVELOPE;

DISEASES;

DIMER; LAMIN A;

ARTICLE; GENE MUTATION; MISSENSE MUTATION; MOLECULAR DYNAMICS; MUSCULAR DYSTROPHY; PRIORITY JOURNAL; PROTEIN STRUCTURE; SIMULATION; TENSILE STRENGTH; WILD TYPE;

DIMERIZATION; LAMIN TYPE A; MODELS, MOLECULAR; MUSCULAR DYSTROPHIES; POINT MUTATION; PROTEIN STRUCTURE, TERTIARY; STRESS, MECHANICAL;

EID: 41549115897     PISSN: 00219290     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2008.01.009     Document Type: Article

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