Adenovirus and adeno-associated virus-mediated delivery of human myophosphorylase cDNA and LacZ cDNA to muscle in the ovine model of McArdle's disease: Expression and re-expression of glycogen phosphorylase

Neuromuscular Disorders

Volumn 18, Issue 3, 2008, Pages 248-258

  Howell, J McC ^a,b   Walker, K R ^b   Davies, L ^a   Dunton, E ^a   Everaardt, A ^a   Laing, N ^b   Karpati, G ^c  

^a MURDOCH UNIVERSITY   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Adeno associated virus 2; Gene therapy; Glycogen phosphorylase; McArdle's disease; Modified adenovirus 5; Myophosphorylase; Ovine model of McArdle's disease; Phosphorylase isoforms

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; COMPLEMENTARY DNA; GLYCOGEN PHOSPHORYLASE; PARVOVIRUS VECTOR;

ADENO ASSOCIATED VIRUS; ADENO ASSOCIATED VIRUS 2; ADENOVIRUS 5; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; GENE TRANSFER; GLYCOGEN STORAGE DISEASE TYPE 5; INJECTION; LIVER; MUSCLE CELL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEMITENDINOUS MUSCLE; SHEEP;

ADENOVIRIDAE; ANIMALS; BETA-GALACTOSIDASE; BIOPSY; DISEASE MODELS, ANIMAL; DNA, COMPLEMENTARY; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE THERAPY; GENE TRANSFER TECHNIQUES; GLYCOGEN PHOSPHORYLASE, MUSCLE FORM; GLYCOGEN STORAGE DISEASE TYPE V; HUMANS; LAC OPERON; MUSCLE FIBERS; MUSCLE, SKELETAL; PERIODIC ACID-SCHIFF REACTION; SHEEP;

EID: 41549107481     PISSN: 09608966     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nmd.2007.10.006     Document Type: Article

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