Spinal hemorrhages are associated with early neonatal motor function loss in human spina bifida aperta

Early Human Development

Volumn 84, Issue 7, 2008, Pages 423-431

  Sival, D A ^a   Verbeek, R J ^a   Brouwer, O F ^a   Sollie, K M ^a   Bos, A F ^a   den Dunnen, W F A ^b  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

Ependymal denudation; Fetal movement; Histology; Motor neuron; Spina bifida; Spinal hemorrhage

Indexed keywords

ARTICLE; AUTOPSY; CONTROLLED STUDY; DISEASE ASSOCIATION; FETUS; FETUS MOVEMENT; GLIOSIS; HISTOPATHOLOGY; HUMAN; LOCOMOTION; MENINGOMYELOCELE; MOTONEURON; MOTOR DYSFUNCTION; MUSCLE CELL; NEWBORN DISEASE; SPINA BIFIDA; SPINA BIFIDA APERTA; SPINAL CORD BLOOD FLOW; SPINAL CORD HEMORRHAGE;

BIOPSY; FEMALE; FETAL DISEASES; GESTATIONAL AGE; HEMORRHAGE; HUMANS; INFANT, NEWBORN; MOTOR ACTIVITY; MOTOR NEURON DISEASE; MOTOR NEURONS; MUSCLE, SKELETAL; PREGNANCY; SPINA BIFIDA CYSTICA; SPINAL CORD; SPINAL DISEASES;

EID: 41549104493     PISSN: 03783782     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.earlhumdev.2007.11.003     Document Type: Article

References (49)

1. Sival D.A., van Weerden T.W., Vles J.H., Timmer A., den Dunnen W.F.A., Staal-Schreinemachers A.L., et al. Neonatal loss of motor function in human spina bifida aperta. Pediatrics 114 2 (2004) 427-434
2. Sival D.A., Begeer J.H., Staal-Schreinemachers A.L., Vos-Niel J.M.E., Beekhuis J.R., and Prechtl H.F.R. Perinatal motor behaviour and neurological outcome in spina bifida aperta. Early Hum Dev 50 1 (1997) 27-38
3. Sival D.A., Brouwer O.F., Bruggink J.L., Vles J.S., Staal-Schreinemachers A.L., Sollie K.M., et al. Movement analysis in neonates with spina bifida aperta. Early Hum Dev 82 4 (2006) 227-234
4. Meuli M., Meuli-Simmen C., Hutchins G.M., Yingling C.D., McBiles-Hoffman K., Harrison M.R., et al. In utero surgery rescues neurological function at birth in sheep with spina bifida. Nat Med 1 (1995) 342-347
5. Hirose S., Meuli-Simmen C., and Meuli M. Fetal surgery for myelomeningocele: panacea or peril?. World J Surg 27 1 (2003) 87-94
6. Bruner J.P., Tulipan N., Reed G., Davis G.H., Bennett K., Luker K.S., et al. Intrauterine repair of spina bifida: preoperative predictors of shunt-dependent hydrocephalus. Am J Obstet Gynecol 190 5 (2004) 1305-1312
7. Tulipan N., Sutton L.N., Bruner J.P., Cohen B.M., Johnson M., and Adzick N.S. The effect of intrauterine myelomeningocele repair on the incidence of shunt-dependent hydrocephalus. Pediatr Neurosurg 38 1 (2003) 27-33
8. McLone D.G., Dias M.S., Goossens W., and Knepper P.A. Pathological changes in exposed neural tissue of fetal delayed splotch (Spd) mice. Child's Nerv Syst 13 1 (1997) 1-7
9. Hirose S., Farmer D.L., and Albanese C.T. Fetal surgery for myelomeningocele. Curr Opin Obstet Gynecol 13 2 (2001) 215-222
10. Tulipan N., Bruner J.P., Hernanz-Schulman M., Lowe L.H., Walsh W.F., Nickolaus D., et al. Effect of intrauterine myelomeningocele repair on central nervous system structure and function. Pediatr Neurosurg 31 4 (1999) 183-188
11. Sutton LN. Fetal surgery for neural tube defects. Best Pract Res Clin Obstet Gynaecol in press [Aug 20; Electronic publication ahead of print, doi:10.1016/j.bpobgyn.2007.07.004].
12. Sival D.A., Brouwer O.F., Bruggink J.L., Vles J.S., Staal-Schreinemachers A.L., Sollie K.M., et al. Movement analysis in neonates with spina bifida aperta. Early Hum Dev 82 4 (2006) 227-234
13. Walsh D.S., and Adzick N.S. Foetal surgery for spina bifida. Semin Neonatol 8 3 (2003) 197-205
14. Prechtl H.F. Qualitative changes of spontaneous movements in fetus and preterm infant are a marker of neurological dysfunction [editorial]. Early Hum Dev 23 3 (1990) 151-158
15. Einspieler C., Prechtl H.F., Ferrari F., Cioni G., and Bos A.F. The qualitative assessment of general movements in preterm, term and young infants-review of the methodology. Early Hum Dev 50 1 (1997) 47-60
16. Robertson G.S., Crocker S.J., Nicholson D.W., and Schulz J.B. Neuroprotection by the inhibition of apoptosis. Brain Pathol 10 2 (2000) 283-292
17. Srinivasan A., Roth K.A., Sayers R.O., Shindler K.S., Wong A.M., Fritz L.C., et al. In situ immunodetection of activated caspase-3 in apoptotic neurons in the developing nervous system. Cell Death Differ 5 12 (1998) 1004-1016
18. Dubowitz V., and Sewry C.A. Muscle biopsy-a practical approach. 3rd ed. (2006), Saunders-Elsevier chapter 3
19. Dominguez-Pinos M.D., Paez P., Jimenez A.J., Weil B., Arraez M.A., Perez-Figares J.M., et al. Ependymal denudation and alterations of the subventricular zone occur in human fetuses with a moderate communicating hydrocephalus. J Neuropathol Exp Neurol 64 7 (2005) 595-604
20. O'Rahilly R., and Muller F. Bidirectional closure of the rostral neuropore in the human embryoventricular peritoneal shunt requirement in patients with myelomeningocele. Am J Anat 184 4 (1989) 259-268
21. Golden J.A., and Chernoff G.F. Multiple sites of anterior neural tube closure in humans: evidence from anterior neural tube defects (anencephaly). Pediatrics 95 4 (1995) 506-510
22. Nakatsu T., Uwabe C., and Shiota K. Neural tube closure in humans initiates at multiple sites: evidence from human embryos and implications for the pathogenesis of neural tube defects. Anat Embryol (Berl) 201 6 (2000) 455-466
23. Copp A.J., and Brook F.A. Does lumbosacral spina bifida arise by failure of neural folding or by defective canalisation?. J Med Genet 26 3 (1989) 160-166
24. Muller F., and O'Rahilly R. The development of the human brain, the closure of the caudal neuropore, and the beginning of secondary neurulation at stage 12. Anat Embryol (Berl) 176 4 (1987) 413-430
25. Kessel M., and Gruss P. Murine developmental control genes. Science 249 4967 (1990) 374-379
26. Dressler G.R., and Gruss P. Do multigene families regulate vertebrate development?. Trends Genet 4 8 (1988) 214-219
27. Saraga-Babic M., Krolo M., Sapunar D., Terzic J., and Biocic M. Differences in origin and fate between the cranial and caudal spinal cord during normal and disturbed human development. Acta Neuropathol (Berl) 91 2 (1996) 194-199
28. Sarnat H.B. Role of human fetal ependyma. Pediatr Neurol 8 3 (1992) 163-178
29. Sarnat H.B. Histochemistry and immunocytochemistry of the developing ependyma and choroid plexus. Microsc Res Tech 41 1 (1998) 14-28
30. Ybot-Gonzalez P., Cogram P., Gerrelli D., and Copp A.J. Sonic hedgehog and the molecular regulation of mouse neural tube closure. Development 129 10 (2002) 2507-2517
31. Wagner C., Batiz L.F., Rodriguez S., Jimenez A.J., Paez P., Tome M., et al. Cellular mechanisms involved in the stenosis and obliteration of the cerebral aqueduct of Hyh mutant mice developing congenital hydrocephalus. J Neuropathol Exp Neurol 62 10 (2003) 1019-1040
32. Perez-Figares J.M., Jimenez A.J., Perez-Martin M., Fernandez-Llebrez P., Cifuentes M., Riera P., et al. Spontaneous congenital hydrocephalus in the mutant mouse Hyh. Changes in the ventricular system and the subcommissural organ. J Neuropathol Exp Neurol 57 2 (1998) 188-202
33. Jimenez A.J., Tome M., Paez P., Wagner C., Rodriguez S., Fernandez-Llebrez P., et al. A programmed ependymal denudation precedes congenital hydrocephalus in the Hyh mutant mouse. J Neuropathol Exp Neurol 60 11 (2001) 1105-1119
34. Jimenez-Jimenez F.J., Molina J.A., Vargas C., Gomez P., Navarro J.A., ito-Leon J., et al. Neurotransmitter amino acids in cerebrospinal fluid of patients with Parkinson's disease. J Neurol Sci 141 1-2 (1996) 39-44
35. Millicovsky G., and Lazar M.L. Spina bifida: role of neural tissue damage during pregnancy in producing spinal paralysis. Obstet Gynecol 86 2 (1995) 300-301
36. Lok J., and Martin L.J. Rapid subcellular redistribution of Bax precedes caspase-3 and endonuclease activation during excitotoxic neuronal apoptosis in rat brain. J Neurotrauma 19 7 (2002) 815-828
37. Whalley K., O'Neill P., and Ferretti P. Changes in response to spinal cord injury with development: vascularization, hemorrhage and apoptosis. Neuroscience 137 3 (2006) 821-832
38. Barut S., Unlu Y.A., Karaoglan A., Tuncdemir M., Dagistanli F.K., Ozturk M., et al. The neuroprotective effects of z-DEVD.fmk, a caspase-3 inhibitor, on traumatic spinal cord injury in rats. Surg Neurol 64 3 (2005) 213-220
39. Martin L.J. Neuronal death in amyotrophic lateral sclerosis is apoptosis: possible contribution of a programmed cell death mechanism. J Neuropathol Exp Neurol 58 5 (1999) 459-471
40. Hofmeyr G.J., Nikodem V.C., de J.M., and Gelbart B.R. A randomised placebo controlled trial of oral misoprostol in the third stage of labour. Br J Obstet Gynaecol 105 9 (1998) 971-975
41. Chervenak F.A., Duncan C., Ment L.R., Tortora M., McClure M., and Hobbins J.C. Perinatal management of meningomyelocele. Obstet Gynecol 63 3 (1984) 376-380
42. Liu S.L., Shurtleff D.B., Ellenbogen R.G., Loeser J.D., and Kropp R. 19-year follow-up of fetal myelomeningocele brought to term. Eur J Pediatr Surg 9 Suppl 1 (1999) 12-14
43. Shurtleff D.B., Luthy D.A., Nyberg D.A., and Mack L.A. The outcome of fetal myelomeningocele brought to term. Eur J Pediatr Surg 4 Suppl 1 (1994) 25-28
44. Stark G., and Drummond M. Spina bifida as an obstetric problem. Dev Med Child Neurol Suppl 22 (1970) [Suppl]
45. Ralis Z.A. Traumatizing effect of breech delivery on infants with spina bifida. J Pediatr 87 4 (1975) 613-616
46. Meuli M., Meuli-Simmen C., Hutchins G.M., Seller M.J., Harrison M.R., and Adzick N.S. The spinal cord lesion in human fetuses with myelomeningocele: implications for fetal surgery. J Pediatr Surg 32 3 (1997) 448-452
47. Harding B., and Copp A.J. Malformations. In: Graham D.I., and Lantos P.L. (Eds). Greenfield's Neuropathology (1997), Arnold, New York 397-507
48. Boot C.R., van L.H., and Hopman M.T. Arterial vascular properties in individuals with spina bifida. Spinal Cord 41 4 (2003) 242-246
49. Luthy D.A., Wardinsky T., Shurtleff D.B., Hollenbach K.A., Hickok D.E., Nyberg D.A., et al. Cesarean section before the onset of labor and subsequent motor function in infants with meningomyelocele diagnosed antenatally [see comments]. N Engl J Med 324 10 (1991) 662-666