Annexin-1 modulates repair of gastric mucosal injury

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 294, Issue 3, 2008, Pages

  Martin, Gary R ^a   Perretti, Mauro ^b   Flower, Roderick J ^b   Wallace, John L ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Gastric ulcer; Glucocorticoid; Resolution of inflammation

Indexed keywords

AC2 26; ANNEXIN; ANNEXIN 1 RECEPTOR ANTAGONIST; DEXAMETHASONE; FORMYLPEPTIDE RECEPTOR LIKE 1; GLUCOCORTICOID; INDOMETACIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE OVEREXPRESSION; INFLAMMATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; STOMACH MUCOSA INJURY; STOMACH ULCER; ULCER HEALING;

ANIMALS; ANNEXIN A1; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BLOTTING, WESTERN; DEXAMETHASONE; DOSE-RESPONSE RELATIONSHIP, DRUG; GASTRIC MUCOSA; IMMUNOHISTOCHEMISTRY; INDOMETHACIN; MALE; MICE; MICE, INBRED C57BL; RECEPTORS, FORMYL PEPTIDE; STOMACH ULCER;

EID: 41549101993     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00531.2007     Document Type: Article

References (34)

1. Allcock GH, Allegra M, Flower RJ, Perretti M. Neutrophil accumulation induced by bacterial lipopolysaccharide: effects of dexamethasone and annexin 1. Clin Exp Immunol 123: 62-67, 2001.
2. Babbin BA, Lee WY, Parkos CA, Winfree LM, Akyildiz A, Perretti M, Nusrat A. Annexin I regulates SKCO-15 cell invasion by signaling through formyl peptide receptors. J Biol Chem 281: 19588-19599, 2006.
3. Buckingham JC, John CD, Solito E, Tierney T, Flower RJ, Christian H, Morris J. Annexin 1, glucocorticoids, and the neuroendocrine-immune interface. Ann NY Acad Sci 1088: 396-409, 2006.
4. Camussi G, Tetta C, Bussolino F, Baglioni C. Antiinflammatory peptides (antiflammins) inhibit synthesis of platelet-activating factor, neutrophil aggregation and chemotaxis, and intradermal inflammatory reactions. J Exp Med 171: 913-927, 1990.
5. Carpani de Kaski M, Rentsch R, Levi S, Hodgson HJ. Corticosteroids reduce regenerative repair of epithelium in experimental gastric ulcers. Gut 37: 613-616, 1995.
6. Chiang N, Serhan CN, Dahlen SE, Drazen JM, Hay DW, Rovati GE, Shimizu T, Yokomizo T, Brink C. The lipoxin receptor ALX: potent ligand-specific and stereoselective actions in vivo. Pharmacol Rev 58: 463-487, 2006.
7. Christensen S, Riis A, Norgaard M, Thomsen RW, Tonnesen EM, Larsson A, Sorensen HT. Perforated peptic ulcer: use of pre-admission oral glucocorticoids and 30-day mortality. Aliment Pharmacol Ther 23: 45-52, 2006.
8. Ehrlich HP, Tarver H. Effects of beta-carotene, vitamin A, and glucocorticoids on collagen synthesis in wounds. Proc Soc Exp Biol Med 137: 936-938, 1971.
9. Elliott SN, McKnight W, Cirino G, Wallace JL. A nitric oxide-releasing nonsteroidal anti-inflammatory drug accelerates gastric ulcer healing in rats. Gastroenterology 109: 524-530, 1995.
10. Ernst S, Lange C, Wilbers A, Goebeler V, Gerke V, Rescher U. An annexin 1 N-terminal peptide activates leukocytes by triggering different members of the formyl peptide receptor family. J Immunol 172: 7669-7676, 2004.
11. Gavins FN, Yona S, Kamal AM, Flower RJ, Perretti M. Leukocyte antiadhesive actions of annexin 1: ALXR- and FPR-related anti-inflammatory mechanisms. Blood 101: 4140-4147, 2003.
12. Getting SJ, Flower RJ, Perretti M. Inhibition of neutrophil and monocyte recruitment by endogenous and exogenous lipocortin 1. Br J Pharmacol 120: 1075-1082, 1997.
13. -/- mouse. FASEB J 17: 253-255, 2003.
14. Hayhoe RP, Kamal AM, Solito E, Flower RJ, Cooper D, Perretti M. Annexin 1 and its bioactive peptide inhibit neutrophil-endothelium interactions under flow: indication of distinct receptor involvement. Blood 107: 2123-2130, 2006.
15. Kamal AM, Hayhoe RP, Paramasivam A, Cooper D, Flower RJ, Solito E, Perretti M. Antiflammin-2 activates the human formyl-peptide receptor like 1. ScientificWorldJournal 6: 1375-1384, 2006.
16. Luo JC, Shin VY, Liu ES, Ye YN, Wu WK, So WH, Chang FY, Cho CH. Dexamethasone delays ulcer healing by inhibition of angiogenesis in rat stomachs. Eur J Pharmacol 485: 275-281, 2004.
17. Maderna P, Yona S, Perretti M, Godson C. Modulation of phagocytosis of apoptotic neutrophils by supernatant from dexamethasone-treated macrophages and annexin-derived peptide Ac(2-26). J Immunol 174: 3727-3733, 2005.
18. O'Neil EA, Chwals WJ, O'Shea MD, Turner CS. Dexamethasone treatment during ventilator dependency: possible life threatening gastrointestinal complications. Arch Dis Child 67: 10-11, 1992.
19. Perretti M. The annexin 1 receptor(s): is the plot unravelling? Trends Pharmacol Sci 24: 574-579, 2003.
20. Perretti M, Flower RJ. Cytokines, glucocorticoids and lipocortins in the control of neutrophil migration. Pharmacol Res 30: 53-59, 1994.
21. Pierce GF, Mustoe TA, Lingelbach J, Masakowski VR, Gramates P, Deuel TF. Transforming growth factor beta reverses the glucocorticoid-induced wound-healing deficit in rats: possible regulation in macrophages by platelet-derived growth factor. Proc Natl Acad Sci USA 86: 2229-2233, 1989.
22. Rescher U, Goebeler V, Wilbers A, Gerke V. Proteolytic cleavage of annexin 1 by human leukocyte elastase. Biochim Biophys Acta 1763: 1320-1324, 2006.
23. Roviezzo F, Getting SJ, Paul-Clark MJ, Yona S, Gavins FN, Perretti M, Hannon R, Croxtall JD, Buckingham JC, Flower RJ. The annexin-1 knockout mouse: what it tells us about the inflammatory response. J Physiol Pharmacol 53: 541-553, 2002.
24. Scannell M, Flanagan MB, deStefani A, Wynne KJ, Cagney G, Godson C, Maderna P. Annexin-1 and peptide derivatives are released by apoptotic cells and stimulate phagocytosis of apoptotic neutrophils by macrophages. J Immunol 178: 4595-4605, 2007.
25. Smith SF, Tetley TD, Guz A, Flower RJ. Detection of lipocortin 1 in human lung lavage fluid: lipocortin degradation as a possible proteolytic mechanism in the control of inflammatory mediators and inflammation. Environ Health Perspect 85: 135-144, 1990.
26. Solito E, de Coupade C, Parente L, Flower RJ, Russo-Marie F. IL-6 stimulates annexin 1 expression and translocation and suggests a new biological role as class II acute phase protein. Cytokine 10: 514-521, 1998.
27. Tsao FH, Meyer KC, Chen X, Rosenthal NS, Hu J. Degradation of annexin I in bronchoalveolar lavage fluid from patients with cystic fibrosis. Am J Respir Cell Mol Biol 18: 120-128, 1998.
28. Vergnolle N, Comera C, Bueno L. Annexin-1 is overexpressed and specifically secreted during experimentally induced colitis in rats. Eur J Biochem 232: 603-610, 1995.
29. Vergnolle N, Comera C, More J, Alvinerie M, Bueno L. Expression and secretion of lipocortin 1 in gut inflammation are not regulated by pituitary-adrenal axis. Am J Physiol Regul Integr Comp Physiol 273: R623-R629, 1997.
30. Vishwanatha JK, Davis RG, Rubinstein I, Floreani A. Annexin I degradation in bronchoalveolar lavage fluids from healthy smokers: a possible mechanism of inflammation. Clin Cancer Res 4: 2559-2564, 1998.
31. Vong L, D'Acquisto F, Pederzoli-Ribeil M, Lavagno L, Flower RJ, Witko-Sarsat V, Perretti M. Annexin 1 cleavage in activated neutrophils: a pivotal role for proteinase 3. J Biol Chem 282: 29998-30004, 2007.
32. Wallace JL. Recent advances in gastric ulcer therapeutics. Curr Opin Pharmacol 5: 573-577, 2005.
33. Wallace JL, de Lima OM, Fiorucci S. Lipoxins in gastric mucosal health and disease. Prostaglandins Leukot Essent Fatty Acids 73: 251-255, 2005.
34. Zanardo RC, Perretti M, Wallace JL. Annexin-1 is an endogenous gastroprotective factor against indomethacin-induced damage. Am J Physiol Gastrointest Liver Physiol 288: G481-G486, 2005.