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Volumn 4, Issue 1, 2008, Pages 41-48

Serotonin receptor modulators in the treatment of irritable bowel syndrome

Author keywords

Irritable bowel syndrome; Serotonin; Tegaserod

Indexed keywords

5 CHLORO 2 (1,4 DIAZACYCLOHEPTAN 1 YL) 7 METHYLBENZOXAZOLE; ALOSETRON; ANTIDIARRHEAL AGENT; BULKING AGENT; CILANSETRON; CITALOPRAM; FLUOXETINE; LAXATIVE; ME 3412; PAROXETINE; PLACEBO; RAMOSETRON; RENZAPRIDE; SEROTONIN; SEROTONIN 1 RECEPTOR; SEROTONIN 3 AGONIST; SEROTONIN 3 ANTAGONIST; SEROTONIN 3 RECEPTOR; SEROTONIN 4 AGONIST; SEROTONIN RECEPTOR; SEROTONIN UPTAKE INHIBITOR; SPASMOLYTIC AGENT; TEGASEROD; TRICYCLIC ANTIDEPRESSANT AGENT; UNCLASSIFIED DRUG;

EID: 41549098689     PISSN: 11766336     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (44)

References (75)
  • 1
    • 0003821883 scopus 로고    scopus 로고
    • American Gastroenterological Association, AGA Press
    • American Gastroenterological Association. 2002. The burden of gastrointestinal diseases. AGA Press.
    • (2002) The burden of gastrointestinal diseases
  • 2
    • 30044442329 scopus 로고    scopus 로고
    • Altered 5-hydroxytryptamine signaling in patients with constipation- and diarrhea-predominant irritable bowel syndrome
    • Atkinson W, Lockhart S, Whorwell PJ, et al. 2006. Altered 5-hydroxytryptamine signaling in patients with constipation- and diarrhea-predominant irritable bowel syndrome. Gastroenterology, 130:34-43.
    • (2006) Gastroenterology , vol.130 , pp. 34-43
    • Atkinson, W.1    Lockhart, S.2    Whorwell, P.J.3
  • 3
    • 0141571306 scopus 로고    scopus 로고
    • An evidence-based approach to the management of irritable bowel syndrome in North America
    • Re: Brandt et al
    • Avigan M, Justice R, Mackey AC, et al. 2003. Re: Brandt et al. An evidence-based approach to the management of irritable bowel syndrome in North America. Am J Gastroenterol, 98:2105.
    • (2003) Am J Gastroenterol , vol.98 , pp. 2105
    • Avigan, M.1    Justice, R.2    Mackey, A.C.3
  • 4
    • 16244376476 scopus 로고    scopus 로고
    • Rationale for using serotonergic agents to treat irritable bowel syndrome
    • Baker DE. 2005. Rationale for using serotonergic agents to treat irritable bowel syndrome. Am J Health-syst Pharm, 62:700-13.
    • (2005) Am J Health-syst Pharm , vol.62 , pp. 700-713
    • Baker, D.E.1
  • 5
    • 20444449818 scopus 로고    scopus 로고
    • The use of tegaserod in critically ill patients with impaired gastric motility
    • Banh HL, MacLean C, Topp T, et al. 2005. The use of tegaserod in critically ill patients with impaired gastric motility. Clinical Pharmacology and Therapeutics, 77:583-6.
    • (2005) Clinical Pharmacology and Therapeutics , vol.77 , pp. 583-586
    • Banh, H.L.1    MacLean, C.2    Topp, T.3
  • 6
    • 4644348092 scopus 로고    scopus 로고
    • Cilansetron in irritable bowel syndrome with diarrhea predominance (IBS-D): Efficacy and safety in a 6 month global study
    • Bradette M, Moennikes H, Carter F, et al. 2004. Cilansetron in irritable bowel syndrome with diarrhea predominance (IBS-D): efficacy and safety in a 6 month global study. Gastroenterology, 126:A42.
    • (2004) Gastroenterology , vol.126
    • Bradette, M.1    Moennikes, H.2    Carter, F.3
  • 8
  • 9
    • 0034712539 scopus 로고    scopus 로고
    • Efficacy and safety of alosetron in women with irritable bowel syndrome: A randomised, placebo-controlled trial
    • Camilleri M, Northcutt AR, Kong S, et al. 2000. Efficacy and safety of alosetron in women with irritable bowel syndrome: a randomised, placebo-controlled trial. Lancet, 355:1035-40.
    • (2000) Lancet , vol.355 , pp. 1035-1040
    • Camilleri, M.1    Northcutt, A.R.2    Kong, S.3
  • 11
    • 0034917335 scopus 로고    scopus 로고
    • A randomized controlled clinical trial of the serotonin type 3 receptor antagonist alosetron in women with diarrhea-predominant irritable bowel syndrome
    • Camilleri M, Chey WY, Mayer EA, et al. 2001. A randomized controlled clinical trial of the serotonin type 3 receptor antagonist alosetron in women with diarrhea-predominant irritable bowel syndrome. Archives of Internal Medicine, 161:1733-40.
    • (2001) Archives of Internal Medicine , vol.161 , pp. 1733-1740
    • Camilleri, M.1    Chey, W.Y.2    Mayer, E.A.3
  • 12
  • 13
    • 2442581507 scopus 로고    scopus 로고
    • Treating irritable bowel syndrome: Overview, perspective and future therapies
    • Camilleri M. 2004. Treating irritable bowel syndrome: overview, perspective and future therapies. British Journal of Pharmacology, 141:1237-48.
    • (2004) British Journal of Pharmacology , vol.141 , pp. 1237-1248
    • Camilleri, M.1
  • 14
    • 5044223521 scopus 로고    scopus 로고
    • Effect of renzapride on transit in constipation-predominant irritable bowel syndrome
    • Camilleri M, McKinzie S, Fox J, et al. 2004. Effect of renzapride on transit in constipation-predominant irritable bowel syndrome. Clinical Gastroenterology and Hepatology, 2:895-904.
    • (2004) Clinical Gastroenterology and Hepatology , vol.2 , pp. 895-904
    • Camilleri, M.1    McKinzie, S.2    Fox, J.3
  • 15
    • 0035882382 scopus 로고    scopus 로고
    • Maintance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: Abnormal intestinal motility and the expression of cation transporters
    • Chen JJ, Li Z, Pan H, et al. 2001. Maintance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: abnormal intestinal motility and the expression of cation transporters. J Neurosci, 21:6348-61.
    • (2001) J Neurosci , vol.21 , pp. 6348-6361
    • Chen, J.J.1    Li, Z.2    Pan, H.3
  • 16
    • 8744229903 scopus 로고    scopus 로고
    • Long-term safety and efficacy of alosetron in women with severe diarrhea-predominant irritable bowel syndrome
    • Chey WD, Chey WY, Heath AT, et al. 2004. Long-term safety and efficacy of alosetron in women with severe diarrhea-predominant irritable bowel syndrome. American Journal of Gastroenterology, 99:2195.
    • (2004) American Journal of Gastroenterology , vol.99 , pp. 2195
    • Chey, W.D.1    Chey, W.Y.2    Heath, A.T.3
  • 17
    • 10644269342 scopus 로고    scopus 로고
    • Review article: Tegaserod - the global experience
    • Chey WD. 2004. Review article: tegaserod - the global experience. Alimentary Pharmacology and Therapeutics, 20(Suppl 7):15-19.
    • (2004) Alimentary Pharmacology and Therapeutics , vol.20 , Issue.SUPPL. 7 , pp. 15-19
    • Chey, W.D.1
  • 18
    • 0036236097 scopus 로고    scopus 로고
    • Effect of alosetron on left colonic motility in non-constipated patients with irritable bowel syndrome and healthy volunteers
    • Clemens CH, Samsom M, Van Berge, et al. 2002. Effect of alosetron on left colonic motility in non-constipated patients with irritable bowel syndrome and healthy volunteers. Alimentary Pharmacology and Therapeutics, 16:993-1002.
    • (2002) Alimentary Pharmacology and Therapeutics , vol.16 , pp. 993-1002
    • Clemens, C.H.1    Samsom, M.2    Berge, V.3
  • 19
    • 0037441307 scopus 로고    scopus 로고
    • Tegaserod, a 5-HT4 receptor partial agonist, decreases sensitivity to rectal distension in healthy subjects
    • Coffin B, Farmachidi JP, Rueegg P, et al. 2003. Tegaserod, a 5-HT4 receptor partial agonist, decreases sensitivity to rectal distension in healthy subjects. Alimentary Pharmacology and Therapeutics, 17:577-85.
    • (2003) Alimentary Pharmacology and Therapeutics , vol.17 , pp. 577-585
    • Coffin, B.1    Farmachidi, J.P.2    Rueegg, P.3
  • 20
    • 11144345503 scopus 로고    scopus 로고
    • Cilansetron, a novel 5-HT3 antagonist, demonstrated efficacy in males with irritable bowel syndrome with diarrhea predominance (IBS-D)
    • Coremans G, Clouse RE, Carter F, et al. 2004. Cilansetron, a novel 5-HT3 antagonist, demonstrated efficacy in males with irritable bowel syndrome with diarrhea predominance (IBS-D). Gastroenterology, 126(Suppl 2):A-643.
    • (2004) Gastroenterology , vol.126 , Issue.SUPPL. 2
    • Coremans, G.1    Clouse, R.E.2    Carter, F.3
  • 21
    • 0037309719 scopus 로고    scopus 로고
    • North of England IBS Research Group. The cost-effectiveness of psychotherapy and paroxetine for severe irritable bowel syndrome
    • Creed F, Fernandes L, Guthrie E, et al. 2003. North of England IBS Research Group. The cost-effectiveness of psychotherapy and paroxetine for severe irritable bowel syndrome. Gastroenterology, 124:303.
    • (2003) Gastroenterology , vol.124 , pp. 303
    • Creed, F.1    Fernandes, L.2    Guthrie, E.3
  • 22
    • 0037295146 scopus 로고    scopus 로고
    • Efficacy of alosetron in irritable bowel syndrome: A meta-analysis of randomized controlled trials
    • Cremonini F, Delgado-Aros S, Camilleri M. 2003. Efficacy of alosetron in irritable bowel syndrome: a meta-analysis of randomized controlled trials. Neurogastroenterology and Motility, 15:79-86.
    • (2003) Neurogastroenterology and Motility , vol.15 , pp. 79-86
    • Cremonini, F.1    Delgado-Aros, S.2    Camilleri, M.3
  • 23
    • 4344664667 scopus 로고    scopus 로고
    • Functional dyspepsia: Drugs for new (and old) therapeutic targets. Best Practice and Research in Clinical
    • Cremonini F, Delgado-Aros S, Talley NJ. 2004. Functional dyspepsia: drugs for new (and old) therapeutic targets. Best Practice and Research in Clinical Gastroenterology, 18:717-33.
    • (2004) Gastroenterology , vol.18 , pp. 717-733
    • Cremonini, F.1    Delgado-Aros, S.2    Talley, N.J.3
  • 24
    • 0034740722 scopus 로고    scopus 로고
    • Tegaserod, a 5-HT4 receptor partial agonist, accelerates gastric emptying and gastrointestinal transit in healthy male subjects
    • Degen L, Matzinger D, Merz M, et al. 2001. Tegaserod, a 5-HT4 receptor partial agonist, accelerates gastric emptying and gastrointestinal transit in healthy male subjects. Aliment Pharmacol Ther, 15:1745-51.
    • (2001) Aliment Pharmacol Ther , vol.15 , pp. 1745-1751
    • Degen, L.1    Matzinger, D.2    Merz, M.3
  • 26
    • 0031658491 scopus 로고    scopus 로고
    • Effect of alosetron on responses to colonic distension in patients with irritable bowel syndrome
    • Delvaux M, Louvel D, Mamet JP, et al. 1998. Effect of alosetron on responses to colonic distension in patients with irritable bowel syndrome. Alimentary Pharmacology and Therapeutics, 12:849-55.
    • (1998) Alimentary Pharmacology and Therapeutics , vol.12 , pp. 849-855
    • Delvaux, M.1    Louvel, D.2    Mamet, J.P.3
  • 27
    • 16344363012 scopus 로고    scopus 로고
    • Tegaserod-associated ischemic colitis
    • DiBaise JK. 2005. Tegaserod-associated ischemic colitis. Pharmacotherapy, 25:620-5.
    • (2005) Pharmacotherapy , vol.25 , pp. 620-625
    • DiBaise, J.K.1
  • 28
    • 0036893761 scopus 로고    scopus 로고
    • AGA technical review on irritable bowel syndrome
    • Drossman DA, Camilleri M, Mayer EA, et al. 2002. AGA technical review on irritable bowel syndrome. Gastroenterology, 123:2108-31.
    • (2002) Gastroenterology , vol.123 , pp. 2108-2131
    • Drossman, D.A.1    Camilleri, M.2    Mayer, E.A.3
  • 30
    • 3843114528 scopus 로고    scopus 로고
    • Tegaserod does not alter fasting or meal-induced biliary tract motility
    • Fisher RS, Thistle J, Lembo A, et al. 1999. Tegaserod does not alter fasting or meal-induced biliary tract motility. American Journal of Gastroenterology, 99:1342-9.
    • (1999) American Journal of Gastroenterology , vol.99 , pp. 1342-1349
    • Fisher, R.S.1    Thistle, J.2    Lembo, A.3
  • 31
    • 16444371517 scopus 로고    scopus 로고
    • TegaSwiss Study Group. Tegaserod is safe, well tolerated and effective in the treatment of patients with non-diarrhoea irritable bowel syndrome
    • Fried M, Beglinger C, Bobalj NG, et al. 2005. TegaSwiss Study Group. Tegaserod is safe, well tolerated and effective in the treatment of patients with non-diarrhoea irritable bowel syndrome. European Journal of Gastroenterology and Hepatology, 17:421-7.
    • (2005) European Journal of Gastroenterology and Hepatology , vol.17 , pp. 421-427
    • Fried, M.1    Beglinger, C.2    Bobalj, N.G.3
  • 32
    • 10644290207 scopus 로고    scopus 로고
    • Review article: Serotonin receptors and transporters - roles in normal and abnormal gastrointestinal motility
    • Gershon MD. 2004. Review article: serotonin receptors and transporters - roles in normal and abnormal gastrointestinal motility. Alimentary Pharmacology and Therapeutics. 20(Suppl 7):3-14.
    • (2004) Alimentary Pharmacology and Therapeutics , vol.20 , Issue.SUPPL. 7 , pp. 3-14
    • Gershon, M.D.1
  • 33
    • 23244446441 scopus 로고    scopus 로고
    • Nerves, reflexes, and the enteric nervous system
    • Gershon MD, 2005. Nerves, reflexes, and the enteric nervous system. J Clin Gastroenterol, 39:S184-93.
    • (2005) J Clin Gastroenterol , vol.39
    • Gershon, M.D.1
  • 34
    • 0028301413 scopus 로고
    • Influence of antidepressants on whole gut and orocaecal transit time in health and irritable bowel syndrome
    • Gorard DA, Libby GW, Farthing MJG. 1994. Influence of antidepressants on whole gut and orocaecal transit time in health and irritable bowel syndrome. Aliment Pharmacol Ther, 8:159-66.
    • (1994) Aliment Pharmacol Ther , vol.8 , pp. 159-166
    • Gorard, D.A.1    Libby, G.W.2    Farthing, M.J.G.3
  • 35
    • 0029921341 scopus 로고    scopus 로고
    • Mechanisms of disease: The enteric nervous system
    • Goyal RK, Hirano I. 1996. Mechanisms of disease: the enteric nervous system. NEJM, 334:1106-15.
    • (1996) NEJM , vol.334 , pp. 1106-1115
    • Goyal, R.K.1    Hirano, I.2
  • 36
    • 0029976793 scopus 로고    scopus 로고
    • 5-HT released by mucosal stimuli initiates peristalsis by activating 5-HT4/5-HT1p receptors on sensory CGRP neurons
    • Grider JR, Kuemmerle JF, Jin JG. 1996. 5-HT released by mucosal stimuli initiates peristalsis by activating 5-HT4/5-HT1p receptors on sensory CGRP neurons. Am J Physiol, 270:G778-82.
    • (1996) Am J Physiol , vol.270
    • Grider, J.R.1    Kuemmerle, J.F.2    Jin, J.G.3
  • 37
    • 0032943840 scopus 로고    scopus 로고
    • Impact of irritable bowel syndrome on quality of life and resource use in the United States and United Kingdom
    • Hahn BA, Yan S, Strassels S. 1999. Impact of irritable bowel syndrome on quality of life and resource use in the United States and United Kingdom. Digestion, 60:77-81.
    • (1999) Digestion , vol.60 , pp. 77-81
    • Hahn, B.A.1    Yan, S.2    Strassels, S.3
  • 38
    • 0033625752 scopus 로고    scopus 로고
    • Alosetron, a 5-HT3 receptor antagonist, delays colonic transit in patients with irritable bowel syndrome and healthy volunteers
    • Houghton LA, Foster JM, Whorwell PJ. 2000. Alosetron, a 5-HT3 receptor antagonist, delays colonic transit in patients with irritable bowel syndrome and healthy volunteers. Alimentary Pharmacology and Therapeutics, 14:775-82.
    • (2000) Alimentary Pharmacology and Therapeutics , vol.14 , pp. 775-782
    • Houghton, L.A.1    Foster, J.M.2    Whorwell, P.J.3
  • 39
    • 41549153099 scopus 로고    scopus 로고
    • Review: Tegaserod prompts global relief of symptoms in irritable bowel syndrome
    • Irvine EJ. 2004. Review: Tegaserod prompts global relief of symptoms in irritable bowel syndrome. ACP Journal Club, 141:44.
    • (2004) ACP Journal Club , vol.141 , pp. 44
    • Irvine, E.J.1
  • 40
    • 0141918538 scopus 로고    scopus 로고
    • Gastrointestinal motility and the brain-gut axis
    • Ishiguchi T, Itoh H, Ichinose M. 2004. Gastrointestinal motility and the brain-gut axis. Dig Endosc, 15:81-6.
    • (2004) Dig Endosc , vol.15 , pp. 81-86
    • Ishiguchi, T.1    Itoh, H.2    Ichinose, M.3
  • 41
    • 10644271570 scopus 로고    scopus 로고
    • Review article: Tegaserod for chronic constipation
    • Johanson JF. 2004. Review article: tegaserod for chronic constipation. Alimentary Pharmacology and Therapeutics, 20(Suppl 7):20-4.
    • (2004) Alimentary Pharmacology and Therapeutics , vol.20 , Issue.SUPPL. 7 , pp. 20-24
    • Johanson, J.F.1
  • 42
    • 0032749795 scopus 로고    scopus 로고
    • Alosetron relieves pain and improves bowel function compared with mebeverine in female nonconstipated irritable bowel syndrome patients
    • Jones RH, Holtmann G, Rodrigo L, et al. 1999. Alosetron relieves pain and improves bowel function compared with mebeverine in female nonconstipated irritable bowel syndrome patients. Alimentary Pharmacology and Therapeutics, 13:1419-27.
    • (1999) Alimentary Pharmacology and Therapeutics , vol.13 , pp. 1419-1427
    • Jones, R.H.1    Holtmann, G.2    Rodrigo, L.3
  • 43
    • 20044386871 scopus 로고    scopus 로고
    • Tegaserod for the treatment of chronic constipation: A randomized, double-blind, placebo-controlled multinational study
    • Kamm MA, Muller-Lissner S, Talley NJ, et al. 2005. Tegaserod for the treatment of chronic constipation: a randomized, double-blind, placebo-controlled multinational study. American Journal of Gastroenterology, 100:362-72.
    • (2005) American Journal of Gastroenterology , vol.100 , pp. 362-372
    • Kamm, M.A.1    Muller-Lissner, S.2    Talley, N.J.3
  • 44
    • 20144386918 scopus 로고    scopus 로고
    • Comparison between partial agonist (ME3412) and antagonist (alosetron) of5-hydroxytryptamine 3 receptor on gastrointestinal function
    • Kawano K, Mori T, Fu L, et al. 2005. Comparison between partial agonist (ME3412) and antagonist (alosetron) of5-hydroxytryptamine 3 receptor on gastrointestinal function. Neurogastroenterology and Motility, 17:290-301.
    • (2005) Neurogastroenterology and Motility , vol.17 , pp. 290-301
    • Kawano, K.1    Mori, T.2    Fu, L.3
  • 45
    • 0037799916 scopus 로고    scopus 로고
    • An Asia-Pacific, double blind, placebo controlled, randomised study to evaluate the efficacy, safety, and tolerability of tegaserod in patients with irritable bowel syndrome
    • Kellow J, Lee OY, Chang FY, et al. 2003. An Asia-Pacific, double blind, placebo controlled, randomised study to evaluate the efficacy, safety, and tolerability of tegaserod in patients with irritable bowel syndrome. Gut, 52:671-6.
    • (2003) Gut , vol.52 , pp. 671-676
    • Kellow, J.1    Lee, O.Y.2    Chang, F.Y.3
  • 46
    • 33644915873 scopus 로고    scopus 로고
    • Effect ofa laxative with and without tegaserod in adolescents with constipation predominant irritable bowel syndrome
    • Khoshoo V, Armstead C, Landry L. 2006. Effect ofa laxative with and without tegaserod in adolescents with constipation predominant irritable bowel syndrome. Alimentary Pharmacology and Therapeutics, 23:191-6.
    • (2006) Alimentary Pharmacology and Therapeutics , vol.23 , pp. 191-196
    • Khoshoo, V.1    Armstead, C.2    Landry, L.3
  • 48
    • 0034066325 scopus 로고    scopus 로고
    • The 5-HT(3) receptor antagonist alosetron inhibits the colorectal distention induced depressor response and spinal c-fos expression in the anaesthetised rat
    • Kozlowski CM, Green A, Grundy D, et al. 2000. The 5-HT(3) receptor antagonist alosetron inhibits the colorectal distention induced depressor response and spinal c-fos expression in the anaesthetised rat. Gut, 46:474-80.
    • (2000) Gut , vol.46 , pp. 474-480
    • Kozlowski, C.M.1    Green, A.2    Grundy, D.3
  • 49
    • 0038418617 scopus 로고    scopus 로고
    • The selective serotonin reuptake inhibitor fluoxetine does not change rectal sensitivity and symptoms in patients with irritable bowel syndrome: A double blind, randomized, placebo-controlled study
    • Kuiken SD, Tytgat GN, Boeckxstaens GE. 2003. The selective serotonin reuptake inhibitor fluoxetine does not change rectal sensitivity and symptoms in patients with irritable bowel syndrome: a double blind, randomized, placebo-controlled study. Clinical Gastroenterology and Hepatology, 1:219-28.
    • (2003) Clinical Gastroenterology and Hepatology , vol.1 , pp. 219-228
    • Kuiken, S.D.1    Tytgat, G.N.2    Boeckxstaens, G.E.3
  • 50
    • 33646701183 scopus 로고    scopus 로고
    • Measuring health-related quality of life in patients with irritable bowel syndrome: Can less be more?
    • Lackner JM, Gudleski GD, Zack MM, et al. 2006. Measuring health-related quality of life in patients with irritable bowel syndrome: Can less be more? Psychosomatic Medicine, 68:312-20.
    • (2006) Psychosomatic Medicine , vol.68 , pp. 312-320
    • Lackner, J.M.1    Gudleski, G.D.2    Zack, M.M.3
  • 51
    • 0034827794 scopus 로고    scopus 로고
    • Lembo T, Wright RA, Bagby B, et al. Lotronex Investigator Team. 2001. Alosetron controls bowel urgency and provides global symptom improvement in women with diarrhea-predominant irritable bowel syndrome. American Journal of Gastroenterology, 96:2662-70.
    • Lembo T, Wright RA, Bagby B, et al. Lotronex Investigator Team. 2001. Alosetron controls bowel urgency and provides global symptom improvement in women with diarrhea-predominant irritable bowel syndrome. American Journal of Gastroenterology, 96:2662-70.
  • 53
    • 0035178249 scopus 로고    scopus 로고
    • Costs of care for irritable bowel syndrome patients in a health maintenance organization
    • Levy RL, Von Korff MR, Whitehead WE, et al. 2001. Costs of care for irritable bowel syndrome patients in a health maintenance organization. Am J Gastroenterol, 96:3122-9.
    • (2001) Am J Gastroenterol , vol.96 , pp. 3122-3129
    • Levy, R.L.1    Von Korff, M.R.2    Whitehead, W.E.3
  • 54
    • 0036024228 scopus 로고    scopus 로고
    • The effect of the 5-HT3 receptor antagonist, alosetron, on brain responses to visceral stimulation in irritable bowel syndrome patients
    • Mayer EA, Berman S, Derbyshire SW, et al. 2002. The effect of the 5-HT3 receptor antagonist, alosetron, on brain responses to visceral stimulation in irritable bowel syndrome patients. Alimentary Pharmacology and Therapeutics, 16:1357-66.
    • (2002) Alimentary Pharmacology and Therapeutics , vol.16 , pp. 1357-1366
    • Mayer, E.A.1    Berman, S.2    Derbyshire, S.W.3
  • 55
    • 0036732793 scopus 로고    scopus 로고
    • Tegaserod, a 5-hydroxytryptamine type 4 receptor partial agonist, is devoid of electrocardiographic effects
    • Morganroth J, Ruegg PC, Dunger-Baldauf C, et al. 2002. Tegaserod, a 5-hydroxytryptamine type 4 receptor partial agonist, is devoid of electrocardiographic effects. American Journal of Gastroenterology, 97:2321-7.
    • (2002) American Journal of Gastroenterology , vol.97 , pp. 2321-2327
    • Morganroth, J.1    Ruegg, P.C.2    Dunger-Baldauf, C.3
  • 56
    • 0034794595 scopus 로고    scopus 로고
    • Tegaserod, a 5-HT(4) receptor partial agonist, relieves symptoms in irritable bowel syndrome patients with abdominal pain, bloating and constipation
    • Muller-Lissner SA, Fumagalli I, Bardhan KD, et al. 2001. Tegaserod, a 5-HT(4) receptor partial agonist, relieves symptoms in irritable bowel syndrome patients with abdominal pain, bloating and constipation. Alimentary Pharmacology and Therapeutics, 15:1655-66.
    • (2001) Alimentary Pharmacology and Therapeutics , vol.15 , pp. 1655-1666
    • Muller-Lissner, S.A.1    Fumagalli, I.2    Bardhan, K.D.3
  • 57
    • 12944266923 scopus 로고    scopus 로고
    • Tegaserod is effective in the initial and retreatment of irritable bowel syndrome with constipation
    • Muller-Lissner S, Holtmann G, Rueegg P, et al. 2005. Tegaserod is effective in the initial and retreatment of irritable bowel syndrome with constipation. Alimentary Pharmacology and Therapeutics, 21:11-20.
    • (2005) Alimentary Pharmacology and Therapeutics , vol.21 , pp. 11-20
    • Muller-Lissner, S.1    Holtmann, G.2    Rueegg, P.3
  • 58
    • 0036829638 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled trial of tegaserod in female patients suffering from irritable bowel syndrome with constipation
    • Novick J, Miner P, Krause R, et al. 2002. A randomized, double-blind, placebo-controlled trial of tegaserod in female patients suffering from irritable bowel syndrome with constipation. Alimentary Pharmacology and Therapeutics, 16:1877-88.
    • (2002) Alimentary Pharmacology and Therapeutics , vol.16 , pp. 1877-1888
    • Novick, J.1    Miner, P.2    Krause, R.3
  • 59
    • 1342309961 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled, randomized study to evaluate the efficacy, safety and tolerability of tegaserod in patients with irritable bowel syndrome
    • Nyhlin H, Bang C, Elsborg L, et al. 2004. A double-blind, placebo-controlled, randomized study to evaluate the efficacy, safety and tolerability of tegaserod in patients with irritable bowel syndrome. Scandinavian Journal of Gastroenterology, 39:119-26.
    • (2004) Scandinavian Journal of Gastroenterology , vol.39 , pp. 119-126
    • Nyhlin, H.1    Bang, C.2    Elsborg, L.3
  • 60
    • 0034089045 scopus 로고    scopus 로고
    • Tegaserod accelerates orocecal transit in patients with constipation-predominant irritable bowel syndrome
    • Prather CM, Camilleri M, Zinsmeister AR, et al. 2000. Tegaserod accelerates orocecal transit in patients with constipation-predominant irritable bowel syndrome. Gastroenterology, 118:463-8.
    • (2000) Gastroenterology , vol.118 , pp. 463-468
    • Prather, C.M.1    Camilleri, M.2    Zinsmeister, A.R.3
  • 61
    • 24344489950 scopus 로고    scopus 로고
    • Effect of tegaserod on work and daily activity in irritable bowel syndrome with constipation
    • Reilly MC, Barghout V, McBurney CR, et al. 2005. Effect of tegaserod on work and daily activity in irritable bowel syndrome with constipation. Alimentary Pharmacology and Therapeutics, 22:373-80.
    • (2005) Alimentary Pharmacology and Therapeutics , vol.22 , pp. 373-380
    • Reilly, M.C.1    Barghout, V.2    McBurney, C.R.3
  • 62
    • 0036234316 scopus 로고    scopus 로고
    • The burden of selected digestive diseases in the United States
    • Sandler RS, Everhart JE, Donowitz M, et al. 2002. The burden of selected digestive diseases in the United States. Gastroenterology, 122:1500-11.
    • (2002) Gastroenterology , vol.122 , pp. 1500-1511
    • Sandler, R.S.1    Everhart, J.E.2    Donowitz, M.3
  • 63
    • 10644288497 scopus 로고    scopus 로고
    • Review article: The safety profile of tegaserod
    • Schoenfeld P. 2004. Review article: the safety profile of tegaserod. Alimentary Pharmacology and Therapeutics, 20(Suppl 7):25-30.
    • (2004) Alimentary Pharmacology and Therapeutics , vol.20 , Issue.SUPPL. 7 , pp. 25-30
    • Schoenfeld, P.1
  • 65
    • 2942648839 scopus 로고    scopus 로고
    • Paroxetine to treat irritable bowel syndrome not responding to high-fiber diet: A double-blind, placebo-controlled trial
    • Tabas G, Beaves M, Wang J, et al. 2004. Paroxetine to treat irritable bowel syndrome not responding to high-fiber diet: a double-blind, placebo-controlled trial. American Journal of Gastroenterology. 99:914-20.
    • (2004) American Journal of Gastroenterology , vol.99 , pp. 914-920
    • Tabas, G.1    Beaves, M.2    Wang, J.3
  • 66
    • 33746162460 scopus 로고    scopus 로고
    • A controlled cross-over study of the selective serotonin reuptake inhibitor citalopram in irritable bowel syndrome
    • Tack J, Broekaert D, Fischler B, et al. 2006. A controlled cross-over study of the selective serotonin reuptake inhibitor citalopram in irritable bowel syndrome. Gut, 55:1095-103.
    • (2006) Gut , vol.55 , pp. 1095-1103
    • Tack, J.1    Broekaert, D.2    Fischler, B.3
  • 67
    • 0028806343 scopus 로고
    • Medical costs in community subjects with irritable bowel syndrome
    • Talley NJ, Gabriel SE, Harmsen WS, et al. 1995. Medical costs in community subjects with irritable bowel syndrome. Gastroenterology, 109:1736-41.
    • (1995) Gastroenterology , vol.109 , pp. 1736-1741
    • Talley, N.J.1    Gabriel, S.E.2    Harmsen, W.S.3
  • 68
    • 0035894575 scopus 로고    scopus 로고
    • Serotonergic neuroenteric modulators
    • Talley NJ. 2001. Serotonergic neuroenteric modulators. Lancet, 358:2061-8.
    • (2001) Lancet , vol.358 , pp. 2061-2068
    • Talley, N.J.1
  • 69
    • 0038631776 scopus 로고    scopus 로고
    • Pharmacologic therapy for the irritable bowel syndrome
    • Talley NJ. 2003. Pharmacologic therapy for the irritable bowel syndrome. American Journal of Gastroenterology, 98:750-8.
    • (2003) American Journal of Gastroenterology , vol.98 , pp. 750-758
    • Talley, N.J.1
  • 70
    • 2942679613 scopus 로고    scopus 로고
    • Antidepressants in IBS: Are we deluding ourselves?
    • Talley NJ. 2004. Antidepressants in IBS: are we deluding ourselves? Am J Gastroenterol, 99:921.
    • (2004) Am J Gastroenterol , vol.99 , pp. 921
    • Talley, N.J.1
  • 71
    • 8344275793 scopus 로고    scopus 로고
    • Alosetron use drops dramatically with risk management
    • Traynor K. 2004. Alosetron use drops dramatically with risk management. American Journal of Health-System Pharmacy, 61:1210-12.
    • (2004) American Journal of Health-System Pharmacy , vol.61 , pp. 1210-1212
    • Traynor, K.1
  • 72
    • 24344474273 scopus 로고    scopus 로고
    • The effect of fluoxetine in patients with pain and constipation-predominant irritable bowel syndrome: A double-blind randomized-controlled study
    • Vahedi H, Merat S, Rashidioon A, et al. 2005. The effect of fluoxetine in patients with pain and constipation-predominant irritable bowel syndrome: a double-blind randomized-controlled study. Alimentary Pharmacology and Therapeutics, 22:381-5.
    • (2005) Alimentary Pharmacology and Therapeutics , vol.22 , pp. 381-385
    • Vahedi, H.1    Merat, S.2    Rashidioon, A.3
  • 73
    • 0034821162 scopus 로고    scopus 로고
    • Gender-related differences in slowing colonic transit by a 5-HT3 antagonist in subjects with diarrhea-predominant irritable bowel syndrome
    • Viramontes BE, Camilleri M, McKinzie S, et al. 2001. Gender-related differences in slowing colonic transit by a 5-HT3 antagonist in subjects with diarrhea-predominant irritable bowel syndrome. American Journal of Gastroenterology, 96:2671-6.
    • (2001) American Journal of Gastroenterology , vol.96 , pp. 2671-2676
    • Viramontes, B.E.1    Camilleri, M.2    McKinzie, S.3
  • 74
    • 0029844244 scopus 로고    scopus 로고
    • Impact of irritable bowel syndrome on quality of life
    • Whitehead WE, Burnett CK, Cook EW, et al. 1996. Impact of irritable bowel syndrome on quality of life. Dig Dis Sci, 41:2248-53.
    • (1996) Dig Dis Sci , vol.41 , pp. 2248-2253
    • Whitehead, W.E.1    Burnett, C.K.2    Cook, E.W.3
  • 75
    • 0035076042 scopus 로고    scopus 로고
    • Tolerability and safety of alosetron during long-term administration in female and male irritable bowel syndrome patients
    • Wolfe SG, Chey WY, Washington MK, et al. 2001. Tolerability and safety of alosetron during long-term administration in female and male irritable bowel syndrome patients. American Journal of Gastroenterology, 96:803-11.
    • (2001) American Journal of Gastroenterology , vol.96 , pp. 803-811
    • Wolfe, S.G.1    Chey, W.Y.2    Washington, M.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.