메뉴 건너뛰기




Volumn 6, Issue 3, 2008, Pages 305-314

Aliskiren-hydrochlorothiazide combination for the treatment of hypertension

Author keywords

Aliskiren hydrochlorothiazide; Combination therapy; Hypertension

Indexed keywords

ALDOSTERONE; ALISKIREN; AMLODIPINE; ANGIOTENSIN; ANGIOTENSIN RECEPTOR ANTAGONIST; ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CELECOXIB; CIMETIDINE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; FUROSEMIDE; HYDROCHLOROTHIAZIDE; IRBESARTAN; LOSARTAN; MEVINOLIN; PLACEBO; POTASSIUM; RAMIPRIL; RENIN; RENIN INHIBITOR; VALSARTAN; WARFARIN; AMIDE; FUMARIC ACID DERIVATIVE;

EID: 41449118358     PISSN: 14779072     EISSN: 17448344     Source Type: Journal    
DOI: 10.1586/14779072.6.3.305     Document Type: Article
Times cited : (12)

References (54)
  • 1
    • 33847633400 scopus 로고    scopus 로고
    • Prevalence, awareness, treatment and control of hypertension among United States adults 1999-2004
    • Ong KL, Cheung BM, Man YB, Lau CP, Lan KS. Prevalence, awareness, treatment and control of hypertension among United States adults 1999-2004. Hypertension 49, 69-75 (2007).
    • (2007) Hypertension , vol.49 , pp. 69-75
    • Ong, K.L.1    Cheung, B.M.2    Man, Y.B.3    Lau, C.P.4    Lan, K.S.5
  • 2
    • 0347423198 scopus 로고    scopus 로고
    • Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure
    • Chobanian AV, Bakris GL, Black HR et al. Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension 42, 1206-1252 (2003).
    • (2003) Hypertension , vol.42 , pp. 1206-1252
    • Chobanian, A.V.1    Bakris, G.L.2    Black, H.R.3
  • 3
    • 0027461577 scopus 로고
    • Single-drug therapy for hypertension in men. A comparison of six antihypertensive agents with placebo. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents
    • Materson BJ, Reda DJ, Cushman WC et al. Single-drug therapy for hypertension in men. A comparison of six antihypertensive agents with placebo. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents. N. Engl. J. Med. 328, 914-921 (1993).
    • (1993) N. Engl. J. Med , vol.328 , pp. 914-921
    • Materson, B.J.1    Reda, D.J.2    Cushman, W.C.3
  • 4
    • 0036863587 scopus 로고    scopus 로고
    • Success and predictors of blood pressure control in diverse North American settings: The Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)
    • Cushman WC, Ford CE, Cutler JA et al. Success and predictors of blood pressure control in diverse North American settings: The Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). J. Clin. Hypertens. 4, 393-404 (2002).
    • (2002) J. Clin. Hypertens , vol.4 , pp. 393-404
    • Cushman, W.C.1    Ford, C.E.2    Cutler, J.A.3
  • 5
    • 0028296024 scopus 로고
    • Antihypertensive effectiveness of low-dose lisinopril-hydrochlorothiazide combination. A large multicenter study. Lisinopril-Hydrochlorothiazide
    • Chrysant SG. Antihypertensive effectiveness of low-dose lisinopril-hydrochlorothiazide combination. A large multicenter study. Lisinopril-Hydrochlorothiazide Group. Arch. Intern. Med. 154, 737-743 (1994).
    • (1994) Group. Arch. Intern. Med , vol.154 , pp. 737-743
    • Chrysant, S.G.1
  • 6
    • 1442299290 scopus 로고    scopus 로고
    • Evaluation of antihypertensive therapy with the combination of olmesartan medoxomil and hydrochlorothiazide
    • Chrysant SG, Weber MA, Wang AC, Hinman DJ. Evaluation of antihypertensive therapy with the combination of olmesartan medoxomil and hydrochlorothiazide. Am. J. Hypertens. 17, 252-259(2003).
    • (2003) Am. J. Hypertens , vol.17 , pp. 252-259
    • Chrysant, S.G.1    Weber, M.A.2    Wang, A.C.3    Hinman, D.J.4
  • 8
    • 33644789557 scopus 로고    scopus 로고
    • Renin inhibition with aliskiren: Where are we now and where are we going?
    • Azizi M, Webb R, Nussberger J, Hollenberg NK. Renin inhibition with aliskiren: where are we now and where are we going? J. Hypertens. 24, 243-256 (2006).
    • (2006) J. Hypertens , vol.24 , pp. 243-256
    • Azizi, M.1    Webb, R.2    Nussberger, J.3    Hollenberg, N.K.4
  • 9
    • 33947137020 scopus 로고    scopus 로고
    • Do we need yet another blocker of the renin-angiotensin system?
    • Messerli FH, Re RN. Do we need yet another blocker of the renin-angiotensin system? J. Am. Coll. Cardiol. 49, 1164-1165 (2007).
    • (2007) J. Am. Coll. Cardiol , vol.49 , pp. 1164-1165
    • Messerli, F.H.1    Re, R.N.2
  • 10
    • 34247644329 scopus 로고    scopus 로고
    • Aliskiren, first renin inhibitor for treating hypertension: Reactive renin secretion may limit its effectiveness
    • Sealey JE, Laragh JH. Aliskiren, first renin inhibitor for treating hypertension: reactive renin secretion may limit its effectiveness. Am. J. Hypertens. 20, 587-597 (2007).
    • (2007) Am. J. Hypertens , vol.20 , pp. 587-597
    • Sealey, J.E.1    Laragh, J.H.2
  • 11
    • 33748070612 scopus 로고    scopus 로고
    • Direct renin inhibition with aliskiren in hypertension and target organ damage
    • Müller DN, Luft FC. Direct renin inhibition with aliskiren in hypertension and target organ damage. Clin. J. Am. Soc. Nephrol. 1, 221-228 (2006).
    • (2006) Clin. J. Am. Soc. Nephrol , vol.1 , pp. 221-228
    • Müller, D.N.1    Luft, F.C.2
  • 12
    • 0042661157 scopus 로고    scopus 로고
    • Structure-based design of aliskiren, a novel orally effective renin inhibitor
    • Wood JM, Maibaum J, Rahuel J et al. Structure-based design of aliskiren, a novel orally effective renin inhibitor. Biochem. Biophys. Res. Commun. 308, 698-705 (2003).
    • (2003) Biochem. Biophys. Res. Commun , vol.308 , pp. 698-705
    • Wood, J.M.1    Maibaum, J.2    Rahuel, J.3
  • 13
    • 34547221695 scopus 로고    scopus 로고
    • Absorption, distribution, metabolism, and elimination of the direct renin inhibitor aliskiren in healthy volunteers
    • Waldmeir FJ, Glaeznel U, Wirz B et al. Absorption, distribution, metabolism, and elimination of the direct renin inhibitor aliskiren in healthy volunteers. Drug Metab. Dispos. 35, 1418-1428 (2007).
    • (2007) Drug Metab. Dispos , vol.35 , pp. 1418-1428
    • Waldmeir, F.J.1    Glaeznel, U.2    Wirz, B.3
  • 14
    • 33750357566 scopus 로고    scopus 로고
    • Vaidyanathan S, Jermany J, Yeh CM, Bizot M-N, Camisasca R. Aliskiren, a novel orally effective renin inhibitor, exhibits similar pharmacokinetics and pharmacodynamics in Japanese and Caucasian subjects. Br. J. Clin. Pharmacol. 62, 690-698 (2006).
    • Vaidyanathan S, Jermany J, Yeh CM, Bizot M-N, Camisasca R. Aliskiren, a novel orally effective renin inhibitor, exhibits similar pharmacokinetics and pharmacodynamics in Japanese and Caucasian subjects. Br. J. Clin. Pharmacol. 62, 690-698 (2006).
  • 15
    • 33846456943 scopus 로고    scopus 로고
    • Pharmacokinetics, safety, and tolerability of the oral renin inhibitor aliskiren in patients with hepatic impairment
    • Vaidyanathan S. Warren V, Yeh CM, Bizot MN, Dieterich HA, Dole WP. Pharmacokinetics, safety, and tolerability of the oral renin inhibitor aliskiren in patients with hepatic impairment. J. Clin. Pharmacol. 47, 192-200 (2007).
    • (2007) J. Clin. Pharmacol , vol.47 , pp. 192-200
    • Vaidyanathan, S.1    Warren, V.2    Yeh, C.M.3    Bizot, M.N.4    Dieterich, H.A.5    Dole, W.P.6
  • 16
    • 34547628374 scopus 로고    scopus 로고
    • Pharmacokinetics of the oral direct renin inhibitor aliskiren alone and in combination with irbesartan in renal impairment
    • Vaidyanathan S, Bigler H, Yeh CM et al. Pharmacokinetics of the oral direct renin inhibitor aliskiren alone and in combination with irbesartan in renal impairment. Clin. Pharmacokinet. 46, 661-675 (2007).
    • (2007) Clin. Pharmacokinet , vol.46 , pp. 661-675
    • Vaidyanathan, S.1    Bigler, H.2    Yeh, C.M.3
  • 17
    • 33846421005 scopus 로고    scopus 로고
    • Aliskiren reduces blood pressure and suppresses plasma renin activity in combination with a thiazide diuretic, an angiotensin-converting enzyme inhibitor, or angiotensin receptor blocker
    • O'Brien E, Barton J, Nussberger J et al. Aliskiren reduces blood pressure and suppresses plasma renin activity in combination with a thiazide diuretic, an angiotensin-converting enzyme inhibitor, or angiotensin receptor blocker. Hypertension 49, 276-284 (2007).
    • (2007) Hypertension , vol.49 , pp. 276-284
    • O'Brien, E.1    Barton, J.2    Nussberger, J.3
  • 18
    • 14044271546 scopus 로고    scopus 로고
    • Wood JM, Schnell CR, Cumin F, Menard J, Webb RL. Aliskiren, a novel, orally effective renin inhibitor, lowers blood pressure in marmosets and spontaneously hypertensive rats. J. Hypertens. 23, 417-426 (2005).
    • Wood JM, Schnell CR, Cumin F, Menard J, Webb RL. Aliskiren, a novel, orally effective renin inhibitor, lowers blood pressure in marmosets and spontaneously hypertensive rats. J. Hypertens. 23, 417-426 (2005).
  • 19
    • 33750289480 scopus 로고    scopus 로고
    • Aliskiren exhibits similar pharmacokinetics in healthy volunteers and patients with Type II diabetes mellitus
    • Zhao C, Vaidyanathan S, Yeh CM, Maboudian M, Dieterich HA. Aliskiren exhibits similar pharmacokinetics in healthy volunteers and patients with Type II diabetes mellitus. Clin. Pharmacokinet. 45, 1125-1134 (2006).
    • (2006) Clin. Pharmacokinet , vol.45 , pp. 1125-1134
    • Zhao, C.1    Vaidyanathan, S.2    Yeh, C.M.3    Maboudian, M.4    Dieterich, H.A.5
  • 20
    • 33947543780 scopus 로고    scopus 로고
    • Pharmacokinetics, safety and tolerability of the novel oral direct renin inhibitor aliskiren in elderly healthy subjects
    • Viadyanathan S, Reynolds C, Yeh CM et al. Pharmacokinetics, safety and tolerability of the novel oral direct renin inhibitor aliskiren in elderly healthy subjects. J. Clin. Pharmacol. 47, 453-460 (2007).
    • (2007) J. Clin. Pharmacol , vol.47 , pp. 453-460
    • Viadyanathan, S.1    Reynolds, C.2    Yeh, C.M.3
  • 21
    • 27444447364 scopus 로고    scopus 로고
    • Renin, pro-renin, and the putative (pro) renin receptor
    • Danser AHJ, Deinum J. Renin, pro-renin, and the putative (pro) renin receptor. Hypertension 46, 1069-1076 (2005).
    • (2005) Hypertension , vol.46 , pp. 1069-1076
    • Danser, A.H.J.1    Deinum, J.2
  • 22
    • 34548034493 scopus 로고    scopus 로고
    • Direct inhibition of renin as a cardiovascular pharmacotherapy focus on aliskiren
    • Sepehrdad R, Frishman WH, Stier CT, Sica DA. Direct inhibition of renin as a cardiovascular pharmacotherapy focus on aliskiren. Cardiol. Rev. 15, 242-256 (2007).
    • (2007) Cardiol. Rev , vol.15 , pp. 242-256
    • Sepehrdad, R.1    Frishman, W.H.2    Stier, C.T.3    Sica, D.A.4
  • 23
    • 0036266596 scopus 로고    scopus 로고
    • Pivotal role of the renin/pro-renin receptor in angiotensin II production and cellular responses to renin
    • Nguyen G, Delarue F, Burckle C, Bouzhir L, Gillet T, Sraer J-D. Pivotal role of the renin/pro-renin receptor in angiotensin II production and cellular responses to renin. J. Clin. Invest. 109, 1417-1427 (2002).
    • (2002) J. Clin. Invest , vol.109 , pp. 1417-1427
    • Nguyen, G.1    Delarue, F.2    Burckle, C.3    Bouzhir, L.4    Gillet, T.5    Sraer, J.-D.6
  • 24
    • 0343990000 scopus 로고    scopus 로고
    • Manose-6-phosphate receptor-mediated internalization and activation of pro-renin by cardiac cells
    • Van Kasteren CAM, Danser AHJ, Derkx FHM et al. Manose-6-phosphate receptor-mediated internalization and activation of pro-renin by cardiac cells. Hypertension 30, 1389-1396 (1997).
    • (1997) Hypertension , vol.30 , pp. 1389-1396
    • Van Kasteren, C.A.M.1    Danser, A.H.J.2    Derkx, F.H.M.3
  • 25
    • 0035715143 scopus 로고    scopus 로고
    • Pro-renin accumulation and activation in human endothelial cells. Importance of manose-6-phosphate receptors
    • Vandeneunden MMED, Saris JJ, deBruin RJA et al. Pro-renin accumulation and activation in human endothelial cells. Importance of manose-6-phosphate receptors. Arterioscler. Thromb. Vasc. Biol. 21, 911-916 (2001).
    • (2001) Arterioscler. Thromb. Vasc. Biol , vol.21 , pp. 911-916
    • Vandeneunden, M.M.E.D.1    Saris, J.J.2    deBruin, R.J.A.3
  • 26
    • 40649124722 scopus 로고    scopus 로고
    • Physiology and pharmacology of the (pro)renin receptor
    • Epub ahead of print
    • Nguyen G, Contrepas A. Physiology and pharmacology of the (pro)renin receptor. Curr. Opin. Pharmacol. Epub ahead of print (2008).
    • (2008) Curr. Opin. Pharmacol
    • Nguyen, G.1    Contrepas, A.2
  • 28
    • 25444454353 scopus 로고    scopus 로고
    • Aliskiren, a human renin inhibitor, ameliorates cardiac and renal damage in double-transgenic rats
    • Pilz B, Shagdarsuren E, Wellner M, Fiebeler A, Dechend R, Gratze P, et al. Aliskiren, a human renin inhibitor, ameliorates cardiac and renal damage in double-transgenic rats. Hypertension 46, 569-576 (2005).
    • (2005) Hypertension , vol.46 , pp. 569-576
    • Pilz, B.1    Shagdarsuren, E.2    Wellner, M.3    Fiebeler, A.4    Dechend, R.5    Gratze, P.6
  • 29
    • 0036372173 scopus 로고    scopus 로고
    • Angiotensin II suppression in humans by the orally active renin inhibitor aliskiren (SPP100): Comparison with enalapril
    • Nussberger J, Wuerzner G, Brunner HR. Angiotensin II suppression in humans by the orally active renin inhibitor aliskiren (SPP100): comparison with enalapril. Hypertension 39, E1-E8 (2002).
    • (2002) Hypertension , vol.39
    • Nussberger, J.1    Wuerzner, G.2    Brunner, H.R.3
  • 30
    • 9644287897 scopus 로고    scopus 로고
    • Pharmacologic demonstration of the synergistic effects of a combination of the renin inhibitor aliskiren and the AT1 receptor antagonist valsartan on the angiotensin II-renin feedback interruption
    • Azizi M, Menard J, Bissery A, Guyenne TT, Vaidyanathan S, Camisasca RP. Pharmacologic demonstration of the synergistic effects of a combination of the renin inhibitor aliskiren and the AT1 receptor antagonist valsartan on the angiotensin II-renin feedback interruption. J. Am. Soc. Nephrol. 15, 3126-3133 (2004).
    • (2004) J. Am. Soc. Nephrol , vol.15 , pp. 3126-3133
    • Azizi, M.1    Menard, J.2    Bissery, A.3    Guyenne, T.T.4    Vaidyanathan, S.5    Camisasca, R.P.6
  • 31
    • 34547925543 scopus 로고    scopus 로고
    • Aliskiren: A review of its use in the management of hypertension
    • Frampton JE, Curran MP. Aliskiren: A review of its use in the management of hypertension. Drugs 67, 1767-1792 (2007).
    • (2007) Drugs , vol.67 , pp. 1767-1792
    • Frampton, J.E.1    Curran, M.P.2
  • 32
    • 4744348177 scopus 로고    scopus 로고
    • Effect of the oral renin inhibitor aliskiren on the pharmacokinetics and pharmacodynamics of a single dose of warfarin in healthy subjects
    • Dieterle W, Corynen S, Mann J. Effect of the oral renin inhibitor aliskiren on the pharmacokinetics and pharmacodynamics of a single dose of warfarin in healthy subjects. Br. J. Clin. Pharmacol. 58, 433-436 (2004).
    • (2004) Br. J. Clin. Pharmacol , vol.58 , pp. 433-436
    • Dieterle, W.1    Corynen, S.2    Mann, J.3
  • 33
    • 33749853955 scopus 로고    scopus 로고
    • Lack of pharmacokinetic interactions of aliskiren, a novel direct renin inhibitor for the treatment of hypertension, with the antihypertensives amlodipine, valsartan, hydrochlorothiazide (HCTZ) and ramipril in healthy volunteers
    • Vaidyanathan S, Valencia J, Kemp C et al. Lack of pharmacokinetic interactions of aliskiren, a novel direct renin inhibitor for the treatment of hypertension, with the antihypertensives amlodipine, valsartan, hydrochlorothiazide (HCTZ) and ramipril in healthy volunteers. Int. J. Clin. Pract. 60, 1343-1356 (2006).
    • (2006) Int. J. Clin. Pract , vol.60 , pp. 1343-1356
    • Vaidyanathan, S.1    Valencia, J.2    Kemp, C.3
  • 34
    • 28044453329 scopus 로고    scopus 로고
    • Pharmacokinetic interactions of the oral renin inhibitor aliskiren with lovastatin, atenolol, celecoxib and cimetidine
    • Dieterle W, Corynen S, Vaidyanathan S, Mann J. Pharmacokinetic interactions of the oral renin inhibitor aliskiren with lovastatin, atenolol, celecoxib and cimetidine. Int. J. Clin. Pharmocol. Ther. 43, 527-535 (2005).
    • (2005) Int. J. Clin. Pharmocol. Ther , vol.43 , pp. 527-535
    • Dieterle, W.1    Corynen, S.2    Vaidyanathan, S.3    Mann, J.4
  • 35
    • 33846781398 scopus 로고    scopus 로고
    • Kushiro T, Itakura H, Gotou H, Terao S, Keefe DL, Aliskiren, a novel oral renin inhibitor, provides dose-dependent efficacy and placebo-like tolerability in Japanese patients with hypertension. Hypertens. Res. 29, 997-1005 (2006).
    • Kushiro T, Itakura H, Gotou H, Terao S, Keefe DL, Aliskiren, a novel oral renin inhibitor, provides dose-dependent efficacy and placebo-like tolerability in Japanese patients with hypertension. Hypertens. Res. 29, 997-1005 (2006).
  • 36
    • 33947182655 scopus 로고    scopus 로고
    • Aliskiren, an oral renin inhibitor, provides dose-dependent efficacy and sustained 24-hour blood pressure control in patients with hypertension
    • Oh BH, Mitchell J, Herron JR, Chung J, Khan M, Keefe DL. Aliskiren, an oral renin inhibitor, provides dose-dependent efficacy and sustained 24-hour blood pressure control in patients with hypertension. J. Am. Coll. Cardiol. 49, 1157-1163 (2007).
    • (2007) J. Am. Coll. Cardiol , vol.49 , pp. 1157-1163
    • Oh, B.H.1    Mitchell, J.2    Herron, J.R.3    Chung, J.4    Khan, M.5    Keefe, D.L.6
  • 37
    • 33845366982 scopus 로고    scopus 로고
    • Renin inhibition with aliskiren provides additive antihypertensive efficacy when used in combination with hydrochlorothiazide
    • Villamil A, Chrysant SG, Calhoun D et al. Renin inhibition with aliskiren provides additive antihypertensive efficacy when used in combination with hydrochlorothiazide. J. Hypertens. 25, 217-226 (2007).
    • (2007) J. Hypertens , vol.25 , pp. 217-226
    • Villamil, A.1    Chrysant, S.G.2    Calhoun, D.3
  • 38
    • 34247867955 scopus 로고    scopus 로고
    • Direct renin inhibition with aliskiren in obese patients with arterial hypertension
    • Jordan J, Engeli S, Boye SW, Lebreton S, Keefe DL. Direct renin inhibition with aliskiren in obese patients with arterial hypertension. Hypertension 49, 1047-1055 (2007).
    • (2007) Hypertension , vol.49 , pp. 1047-1055
    • Jordan, J.1    Engeli, S.2    Boye, S.W.3    Lebreton, S.4    Keefe, D.L.5
  • 39
    • 0347479295 scopus 로고    scopus 로고
    • Blood pressure lowering in essential hypertension with the oral renin inhibitor, aliskiren
    • Stanton A, Jensen C, Nussberger J, O'Brien E. Blood pressure lowering in essential hypertension with the oral renin inhibitor, aliskiren. Hypertension 42, 1137-1143 (2003).
    • (2003) Hypertension , vol.42 , pp. 1137-1143
    • Stanton, A.1    Jensen, C.2    Nussberger, J.3    O'Brien, E.4
  • 40
    • 14844363404 scopus 로고    scopus 로고
    • Gradman AH, Schmieder RE, Lins RL, Nussberger J, Chiang Y, Bedigian MP. Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients. Circulation 111, 1012-1018 (2005).
    • Gradman AH, Schmieder RE, Lins RL, Nussberger J, Chiang Y, Bedigian MP. Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients. Circulation 111, 1012-1018 (2005).
  • 41
    • 33845785350 scopus 로고    scopus 로고
    • Aliskiren, an orally effective renin inhibitor, provides antihypertensive efficacy alone and in combinacion with valsartan
    • Pool JL, Schmieder RE, Azizi M et al. Aliskiren, an orally effective renin inhibitor, provides antihypertensive efficacy alone and in combinacion with valsartan. Am. J. Hypertens. 20, 11-20 (2007).
    • (2007) Am. J. Hypertens , vol.20 , pp. 11-20
    • Pool, J.L.1    Schmieder, R.E.2    Azizi, M.3
  • 42
    • 34447521458 scopus 로고    scopus 로고
    • Efficacy and safety of combined-use of aliskiren and valsartan in patients with hypertension: A randomized, double-blind trial
    • Oparil S, Yarows SA, Patel S, Fang H, Zhang J, Satlin A. Efficacy and safety of combined-use of aliskiren and valsartan in patients with hypertension: a randomized, double-blind trial. Lancet 370, 221-229 (2007).
    • (2007) Lancet , vol.370 , pp. 221-229
    • Oparil, S.1    Yarows, S.A.2    Patel, S.3    Fang, H.4    Zhang, J.5    Satlin, A.6
  • 43
    • 18244406792 scopus 로고    scopus 로고
    • Systematic review of combined angiotensin converting enzyme inhibition and angiotensin receptor blockade in hypertension
    • Doulton TW, He FJ, MacGregor GA. Systematic review of combined angiotensin converting enzyme inhibition and angiotensin receptor blockade in hypertension. Hypertension 45, 880-886 (2005).
    • (2005) Hypertension , vol.45 , pp. 880-886
    • Doulton, T.W.1    He, F.J.2    MacGregor, G.A.3
  • 44
    • 34548442794 scopus 로고    scopus 로고
    • The difficult conception, birth and delivery of renin inhibitor: Controversies around aliskiren
    • Menard J, Azizi M. The difficult conception, birth and delivery of renin inhibitor: controversies around aliskiren. J. Hypertens. 25, 1775-1782 (2007).
    • (2007) J. Hypertens , vol.25 , pp. 1775-1782
    • Menard, J.1    Azizi, M.2
  • 45
    • 34250353444 scopus 로고    scopus 로고
    • The potential role of prorenin in diabetic nephropathy
    • Schmieder RE. The potential role of prorenin in diabetic nephropathy. J. Hypertens. 25, 1323-2328 (2007).
    • (2007) J. Hypertens , vol.25 , pp. 1323-2328
    • Schmieder, R.E.1
  • 46
    • 0026753520 scopus 로고
    • Species specificity of renin kinetics in transgenic rats harboring the human renin and angiotensinogen genes
    • Ganten D, Wagner J, Bader M et al. Species specificity of renin kinetics in transgenic rats harboring the human renin and angiotensinogen genes. Proc. Natl Acad. Sci. USA 89, 7806-7810 (1992).
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 7806-7810
    • Ganten, D.1    Wagner, J.2    Bader, M.3
  • 47
    • 34447272037 scopus 로고    scopus 로고
    • Regression of nephropathy developed in diabetes by (pro) renin receptor blockade
    • Takahashi H, Ichibara A, Kaneshiro, Y et al. Regression of nephropathy developed in diabetes by (pro) renin receptor blockade. J. Am. Soc. Nephrol. 18, 2054-2061 (2007).
    • (2007) J. Am. Soc. Nephrol , vol.18 , pp. 2054-2061
    • Takahashi, H.1    Ichibara, A.2    Kaneshiro, Y.3
  • 48
    • 34447559490 scopus 로고    scopus 로고
    • Dual inhibition of the renin system by aliskiren and valsartan
    • Birkenhager WH, Staessen JA. Dual inhibition of the renin system by aliskiren and valsartan. Lancet 370, 195-196 (2007).
    • (2007) Lancet , vol.370 , pp. 195-196
    • Birkenhager, W.H.1    Staessen, J.A.2
  • 49
    • 0015506533 scopus 로고
    • Propranolol inhibition of renin secretion. A specific approach to diagnosis and treatment of renin-dependent hypotensive diseases
    • Bühler FR, Laragh JH, Baer L, Vaughan ED Jr, Burnner HR. Propranolol inhibition of renin secretion. A specific approach to diagnosis and treatment of renin-dependent hypotensive diseases. N. Engl. J. Med. 287, 1209-1214 (1972).
    • (1972) N. Engl. J. Med , vol.287 , pp. 1209-1214
    • Bühler, F.R.1    Laragh, J.H.2    Baer, L.3    Vaughan Jr, E.D.4    Burnner, H.R.5
  • 50
    • 0033004196 scopus 로고    scopus 로고
    • Beta-adrenergic receptor blockade as a therapeutic approach for suppressing the renin-angiotensin-aldosterone system in normotensive and hypertensive subjects
    • Blumenfeld JD, Sealey JE, Mann SJ, Bragat A, Marion R, Pecker MS, et al. Beta-adrenergic receptor blockade as a therapeutic approach for suppressing the renin-angiotensin-aldosterone system in normotensive and hypertensive subjects. Am. J. Hypertens. 12, 451-459 (1999).
    • (1999) Am. J. Hypertens , vol.12 , pp. 451-459
    • Blumenfeld, J.D.1    Sealey, J.E.2    Mann, S.J.3    Bragat, A.4    Marion, R.5    Pecker, M.S.6
  • 51
    • 8344227579 scopus 로고    scopus 로고
    • Stroke prevention with losartan in the context of other antihypertensive drugs
    • Chrysant SG. Stroke prevention with losartan in the context of other antihypertensive drugs. Drugs Today 40, 791-801 (2004).
    • (2004) Drugs Today , vol.40 , pp. 791-801
    • Chrysant, S.G.1
  • 52
    • 29244470237 scopus 로고    scopus 로고
    • Possible pathophysiologic mechanisms supporting the superior stroke protection of angiotensin-converting enzyme inhibitors: Clinical and experimental evidence
    • Chrysant SG. Possible pathophysiologic mechanisms supporting the superior stroke protection of angiotensin-converting enzyme inhibitors: clinical and experimental evidence. J. Hum. Hypertens. 19, 923-931 (2005).
    • (2005) J. Hum. Hypertens , vol.19 , pp. 923-931
    • Chrysant, S.G.1
  • 53
    • 38449095757 scopus 로고    scopus 로고
    • Pathophysiology of target-organ disease. Does angiotensin II remain the key?
    • Victor RG. Pathophysiology of target-organ disease. Does angiotensin II remain the key? J. Clin. Hypertens. 9(Suppl. 4), 4-10 (2007).
    • (2007) J. Clin. Hypertens , vol.9 , Issue.SUPPL. 4 , pp. 4-10
    • Victor, R.G.1
  • 54
    • 1542560743 scopus 로고    scopus 로고
    • Fixed combination therapy of hypertension: Focus on valsartan/hydrochlorothiazide combination (Diovan/HCT)
    • Chrysant SG. Fixed combination therapy of hypertension: focus on valsartan/hydrochlorothiazide combination (Diovan/HCT). Expert Rev. Cardiovasc. Ther. 1(3), 335-343 (2003).
    • (2003) Expert Rev. Cardiovasc. Ther , vol.1 , Issue.3 , pp. 335-343
    • Chrysant, S.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.