메뉴 건너뛰기




Volumn 25, Issue 7, 2007, Pages 1323-1326

The potential role of prorenin in diabetic nephropathy

Author keywords

Diabetic nephropathy; Progression of nephropathy; Prorenin renin receptor; Renin system prorenin

Indexed keywords

ALISKIREN; ANGIOTENSIN I; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PRORENIN; PROSTAGLANDIN SYNTHASE; RENIN; RENIN INHIBITOR; TRANSFORMING GROWTH FACTOR BETA;

EID: 34250353444     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/HJH.0b013e328048d01c     Document Type: Review
Times cited : (6)

References (31)
  • 1
    • 2342466734 scopus 로고    scopus 로고
    • Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030
    • Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004; 27:1047-1053.
    • (2004) Diabetes Care , vol.27 , pp. 1047-1053
    • Wild, S.1    Roglic, G.2    Green, A.3    Sicree, R.4    King, H.5
  • 2
    • 18344395862 scopus 로고    scopus 로고
    • Optimizing therapeutic strategies to achieve renal and cardiovascular risk reduction in diabetic patients with angiotensin receptor blockers
    • Schmieder RE. Optimizing therapeutic strategies to achieve renal and cardiovascular risk reduction in diabetic patients with angiotensin receptor blockers. J Hypertens 2005; 23:905-911.
    • (2005) J Hypertens , vol.23 , pp. 905-911
    • Schmieder, R.E.1
  • 3
  • 5
    • 0037967318 scopus 로고    scopus 로고
    • Chymase is upregulated in diabetic nephropathy: Implications for an alternative pathway of angiotensin II-mediated diabetic renal and vascular disease
    • Huang XR, Chen WY, Truong LD, Lan HY. Chymase is upregulated in diabetic nephropathy: implications for an alternative pathway of angiotensin II-mediated diabetic renal and vascular disease. J Am Soc Nephrol 2003; 14:1738-1747.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 1738-1747
    • Huang, X.R.1    Chen, W.Y.2    Truong, L.D.3    Lan, H.Y.4
  • 6
    • 0035922447 scopus 로고    scopus 로고
    • Collaborative Study Group. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes
    • Lewis EJ, Hunsicker LG, Clarke WR, Berl T, Pohl MA, Lewis JB, et al., Collaborative Study Group. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 2001; 345:851-860.
    • (2001) N Engl J Med , vol.345 , pp. 851-860
    • Lewis, E.J.1    Hunsicker, L.G.2    Clarke, W.R.3    Berl, T.4    Pohl, M.A.5    Lewis, J.B.6
  • 7
    • 0035922441 scopus 로고    scopus 로고
    • RENAAL Study Investigators. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
    • Brenner BM, Cooper ME, de Zeeuw D, Keane WF, Mitch WE, Parving HH, et al., RENAAL Study Investigators. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 2001; 345:861-869.
    • (2001) N Engl J Med , vol.345 , pp. 861-869
    • Brenner, B.M.1    Cooper, M.E.2    de Zeeuw, D.3    Keane, W.F.4    Mitch, W.E.5    Parving, H.H.6
  • 8
    • 0037431774 scopus 로고    scopus 로고
    • Combination treatment of angiotensin-II receptor blocker and angiotensin-converting-enzyme inhibitor in non-diabetic renal disease (COOPERATE): A randomised controlled trial
    • Nakao N, Yoshimura A, Morita H, Takada M, Kayano T, Ideura T. Combination treatment of angiotensin-II receptor blocker and angiotensin-converting-enzyme inhibitor in non-diabetic renal disease (COOPERATE): a randomised controlled trial. Lancet 2003; 361:117-124.
    • (2003) Lancet , vol.361 , pp. 117-124
    • Nakao, N.1    Yoshimura, A.2    Morita, H.3    Takada, M.4    Kayano, T.5    Ideura, T.6
  • 9
    • 33645060064 scopus 로고    scopus 로고
    • Additional antiproteinuric effect of ultrahigh dose candesartan: A double-blind, randomized, prospective study
    • Schmieder RE, Klingbeil AU, Fleischmann EH, Veelken R, Delles C. Additional antiproteinuric effect of ultrahigh dose candesartan: a double-blind, randomized, prospective study. Am Soc Nephrol 2005; 16:3038-3045.
    • (2005) Am Soc Nephrol , vol.16 , pp. 3038-3045
    • Schmieder, R.E.1    Klingbeil, A.U.2    Fleischmann, E.H.3    Veelken, R.4    Delles, C.5
  • 10
    • 30944466929 scopus 로고    scopus 로고
    • Enhanced renoprotective effects of ultrahigh doses of irbesartan in patients with type 2 diabetes and microalbuminuria
    • Rossing K, Schjoedt KJ, Jensen BR, Boomsma F, Parving HH. Enhanced renoprotective effects of ultrahigh doses of irbesartan in patients with type 2 diabetes and microalbuminuria. Kidney Int 2005; 68:1190-1198.
    • (2005) Kidney Int , vol.68 , pp. 1190-1198
    • Rossing, K.1    Schjoedt, K.J.2    Jensen, B.R.3    Boomsma, F.4    Parving, H.H.5
  • 11
    • 30944465223 scopus 로고    scopus 로고
    • Receptor-mediated actions of renin and prorenin
    • Oliver JA. Receptor-mediated actions of renin and prorenin. Kidney Int 2006; 69:13-15.
    • (2006) Kidney Int , vol.69 , pp. 13-15
    • Oliver, J.A.1
  • 12
    • 0024589995 scopus 로고
    • Response of plasma prorenin and active renin to chronic and acute alterations of renin secretion in normal humans. Studies using a direct immunoradiometric assay
    • Toffelmire EB, Slater K, Corvol P, Menard J, Schambelan M. Response of plasma prorenin and active renin to chronic and acute alterations of renin secretion in normal humans. Studies using a direct immunoradiometric assay. J Clin Invest 1989; 83:679-687.
    • (1989) J Clin Invest , vol.83 , pp. 679-687
    • Toffelmire, E.B.1    Slater, K.2    Corvol, P.3    Menard, J.4    Schambelan, M.5
  • 13
    • 27444447364 scopus 로고    scopus 로고
    • Renin, prorenin and the putative (pro)renin receptor
    • Danser AH, Deinum J. Renin, prorenin and the putative (pro)renin receptor. Hypertension 2005; 46:1069-1076.
    • (2005) Hypertension , vol.46 , pp. 1069-1076
    • Danser, A.H.1    Deinum, J.2
  • 14
    • 0025089160 scopus 로고
    • Plasma prorenin activity and complications in children with insulin-dependent diabetes mellitus
    • Wilson DM, Luetscher JA. Plasma prorenin activity and complications in children with insulin-dependent diabetes mellitus. N Engl J Med 1990; 323:1101-1106.
    • (1990) N Engl J Med , vol.323 , pp. 1101-1106
    • Wilson, D.M.1    Luetscher, J.A.2
  • 19
    • 0021889169 scopus 로고
    • Increased plasma inactive renin in diabetes mellitus. A marker of microvascular complications
    • Luetscher JA, Kraemer FB, Wilson DM, Schwartz HC, Bryer-Ash M. Increased plasma inactive renin in diabetes mellitus. A marker of microvascular complications. N Engl J Med 1985; 312:1412-1417.
    • (1985) N Engl J Med , vol.312 , pp. 1412-1417
    • Luetscher, J.A.1    Kraemer, F.B.2    Wilson, D.M.3    Schwartz, H.C.4    Bryer-Ash, M.5
  • 20
    • 0029853814 scopus 로고    scopus 로고
    • Specific receptor binding of renin on human mesangial cells in culture increases plasminogen activator inhibitor-1 antigen
    • Nguyen G, Delarue F, Berrou J, Rondeau E, Sraer JD. Specific receptor binding of renin on human mesangial cells in culture increases plasminogen activator inhibitor-1 antigen. Kidney Int 1996; 50:1897-1903.
    • (1996) Kidney Int , vol.50 , pp. 1897-1903
    • Nguyen, G.1    Delarue, F.2    Berrou, J.3    Rondeau, E.4    Sraer, J.D.5
  • 21
    • 0036266596 scopus 로고    scopus 로고
    • Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin
    • Nguyen G, Delarue F, Burckle C, Bouzhir L, Giller T, Sraer JD. Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest 2002; 109:1417-1427.
    • (2002) J Clin Invest , vol.109 , pp. 1417-1427
    • Nguyen, G.1    Delarue, F.2    Burckle, C.3    Bouzhir, L.4    Giller, T.5    Sraer, J.D.6
  • 22
    • 0021752503 scopus 로고
    • Local generation of angiotensin II as a mechanism of regulation of peripheral vascular tone in the rat
    • Oliver JA, Sciacca RR. Local generation of angiotensin II as a mechanism of regulation of peripheral vascular tone in the rat. J Clin Invest 1984; 74:1247-1251.
    • (1984) J Clin Invest , vol.74 , pp. 1247-1251
    • Oliver, J.A.1    Sciacca, R.R.2
  • 23
    • 30944469631 scopus 로고    scopus 로고
    • Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms
    • Huang Y, Wongamorntham S, Kasting J, McQuillan D, Owens RT, Yu L, et al. Renin increases mesangial cell transforming growth factor-beta1 and matrix proteins through receptor-mediated, angiotensin II-independent mechanisms. Kidney Int 2006; 69:105-113.
    • (2006) Kidney Int , vol.69 , pp. 105-113
    • Huang, Y.1    Wongamorntham, S.2    Kasting, J.3    McQuillan, D.4    Owens, R.T.5    Yu, L.6
  • 24
    • 33750266798 scopus 로고    scopus 로고
    • Saris JJ, 't Hoen PA, Garrelds IM, Dekkers DH, den Dunnen JT, Lamers JM, Jan Danser AH. Prorenin induces intracellular signaling in cardiomyocytes independently of angiotensin II. Hypertension 2006; 48:564-571.
    • Saris JJ, 't Hoen PA, Garrelds IM, Dekkers DH, den Dunnen JT, Lamers JM, Jan Danser AH. Prorenin induces intracellular signaling in cardiomyocytes independently of angiotensin II. Hypertension 2006; 48:564-571.
  • 25
    • 0029858320 scopus 로고    scopus 로고
    • Vascular damage without hypertension in transgenic rats expressing prorenin exclusively in the liver
    • Veniant M, Menard J, Bruneval P, Morley S, Gonzales MF, Mullins J. Vascular damage without hypertension in transgenic rats expressing prorenin exclusively in the liver. J Clin Invest 1996; 98:1966-1970.
    • (1996) J Clin Invest , vol.98 , pp. 1966-1970
    • Veniant, M.1    Menard, J.2    Bruneval, P.3    Morley, S.4    Gonzales, M.F.5    Mullins, J.6
  • 26
    • 9644283069 scopus 로고    scopus 로고
    • Inhibition of diabetic nephropathy by a decoy peptide corresponding to the 'handle' region for nonproteolytic activation of prorenin
    • Ichihara A, Hayashi M, Kaneshiro Y, Suzuki F, Nakagawa T, Tada Y, et al. Inhibition of diabetic nephropathy by a decoy peptide corresponding to the 'handle' region for nonproteolytic activation of prorenin. J Clin Invest 2004; 114:1128-1135.
    • (2004) J Clin Invest , vol.114 , pp. 1128-1135
    • Ichihara, A.1    Hayashi, M.2    Kaneshiro, Y.3    Suzuki, F.4    Nakagawa, T.5    Tada, Y.6
  • 27
    • 33646160993 scopus 로고    scopus 로고
    • Nonproteolytic activation of prorenin contributes to development of cardiac fibrosis in genetic hypertension
    • Ichihara A, Kaneshiro Y, Takemitsu T, Sakoda M, Suzuki F, Nakagawa T, et al. Nonproteolytic activation of prorenin contributes to development of cardiac fibrosis in genetic hypertension. Hypertension 2006; 47:894-900.
    • (2006) Hypertension , vol.47 , pp. 894-900
    • Ichihara, A.1    Kaneshiro, Y.2    Takemitsu, T.3    Sakoda, M.4    Suzuki, F.5    Nakagawa, T.6
  • 28
    • 33745824649 scopus 로고    scopus 로고
    • Prorenin receptor blockade inhibits development of glomerulosclerosis in diabetic angiotensin II type 1a receptor-deficient mice
    • Ichihara A, Suzuki F, Nakagawa T, Kaneshiro Y, Takemitsu T, Sakoda M, et al. Prorenin receptor blockade inhibits development of glomerulosclerosis in diabetic angiotensin II type 1a receptor-deficient mice. J Am Soc Nephrol 2006; 17:1950-1961.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1950-1961
    • Ichihara, A.1    Suzuki, F.2    Nakagawa, T.3    Kaneshiro, Y.4    Takemitsu, T.5    Sakoda, M.6
  • 29
    • 33747060126 scopus 로고    scopus 로고
    • Increased expression of cyclooxygenase-2 in the renal cortex of human prorenin receptor gene-transgenic rats
    • Kaneshiro Y, Ichihara A, Takemitsu T, Sakoda M, Suzuki F, Nakagawa T, et al. Increased expression of cyclooxygenase-2 in the renal cortex of human prorenin receptor gene-transgenic rats. Kidney Int 2006; 70:641-646.
    • (2006) Kidney Int , vol.70 , pp. 641-646
    • Kaneshiro, Y.1    Ichihara, A.2    Takemitsu, T.3    Sakoda, M.4    Suzuki, F.5    Nakagawa, T.6
  • 30
    • 0347479295 scopus 로고    scopus 로고
    • Blood pressure lowering in essential hypertension with an oral renin inhibitor, aliskiren
    • Stanton A, Jensen C, Nussberger J, O'Brien E. Blood pressure lowering in essential hypertension with an oral renin inhibitor, aliskiren. Hypertension 2003; 42:1137-1143.
    • (2003) Hypertension , vol.42 , pp. 1137-1143
    • Stanton, A.1    Jensen, C.2    Nussberger, J.3    O'Brien, E.4
  • 31
    • 14844363404 scopus 로고    scopus 로고
    • Gradman AH, Schmieder RE, Lins RL, Nussberger J, Chiang Y, Bedigian MP. Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients. Circulation 2005; 111:1012-1018.
    • Gradman AH, Schmieder RE, Lins RL, Nussberger J, Chiang Y, Bedigian MP. Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients. Circulation 2005; 111:1012-1018.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.