Pneumocystis encodes a functional S-adenosylmethionine synthetase gene

Eukaryotic Cell

Volumn 7, Issue 2, 2008, Pages 258-267

  Kutty, Geetha ^a   Hernandez Novoa, Beatriz ^a,d   Czapiga, Meggan ^b   Kovacs, Joseph A ^a,c  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c Hospital Ramón Y Cajal ^*  (United States)

^d HOSPITAL RAMÓN Y CAJAL   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ESCHERICHIA COLI; PNEUMOCYSTIS; PNEUMOCYSTIS CARINII; PNEUMOCYSTIS JIROVECII; PNEUMOCYSTIS MURINA; SACCHAROMYCES CEREVISIAE;

MESSENGER RNA; METHIONINE ADENOSYLTRANSFERASE;

AMINO ACID SEQUENCE; ARTICLE; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOPRECIPITATION; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PNEUMOCYSTIS CARINII; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; SOUTHERN BLOTTING;

AMINO ACID SEQUENCE; BASE SEQUENCE; BLOTTING, NORTHERN; BLOTTING, SOUTHERN; CLONING, MOLECULAR; GENE EXPRESSION REGULATION, FUNGAL; IMMUNOPRECIPITATION; METHIONINE ADENOSYLTRANSFERASE; MOLECULAR SEQUENCE DATA; PNEUMOCYSTIS CARINII; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 41449118330     PISSN: 15359778     EISSN: None     Source Type: Journal    
DOI: 10.1128/EC.00345-07     Document Type: Article

References (37)

1. Angus, C. W., A. Tu, P. Vogel, M. Qin, and J. A. Kovacs. 1996. Expression of variants of the major surface glycoprotein of Pneumocystis carinii. J. Exp. Med. 183:1229-1234.
2. Blumenthal, T. 1998. Gene clusters and polycistronic transcription in eukaryotes. Bioessays 20:480-487.
3. Blumenthal, T. 2004. Operons in eukaryotes. Brief. Funct. Genomic Proteomic 3:199-211.
4. Chiang, P. K., and G. L. Cantoni. 1977. Activation of methionine for transmethylation. Purification of the S-adenosylmethionine synthetase of bakers' yeast and its separation into two forms. J. Biol. Chem. 252:4506-4513.
5. Choi, J. Y., T. W. Lee, K. W. Jeon, and T. I. Ahn. 1997. Evidence for symbiont-induced alteration of a host's gene expression: irreversible loss of SAM synthetase from Amoeba proteus. J. Eukaryot. Microbiol. 44:412-419.
6. Cushion, M. T. 2004. Molecular and phenotypic description of Pneumocystis wakefieldiae sp. nov., a new species in rats. Mycologia 96:429-438.
7. Cushion, M. T., and J. Arnold. 1997. Proposal for a Pneumocystis genome project. J. Eukaryot. Microbiol. 44:7S.
8. Cushion, M. T., A. G. Smulian, B. E. Slaven, T. Sesterhenn, J. Arnold, C. Staben, A. Porollo, R. Adamczak, and J. Meller. 2007. Transcriptome of Pneumocystis carinii during fulminate infection: carbohydrate metabolism and the concept of a compatible parasite. PLoS ONE 2:e423.
9. Dei-Cas, E., E. Mazars, C. O. Ferragut, I. Durand, E. M. Aliouat, M. Dridba, F. Palluault, J. C. Cailliez, N. Seguy, M. Tibayrenc, et al. 1994. Ultrastructural, genomic, isoenzymatic and biological features make it possible to distinguish rabbit Pnenumocystis from other mammal Pneumocystis strains. J. Eukaryot. Microbiol. 41:84S.
10. Fukushima, K., Y. Tanaka, K. Nabeshima, T. Yoneki, T. Tougan, S. Tanaka, and H. Nojima. 2000. Dmc1 of Schizosaccharomyces pombe plays a role in meiotic recombination. Nucleic Acids Res. 28:2709-2716.
11. Hilti, N., R. Graub, M. Jorg, P. Arnold, A. M. Schweingruber, and M. E. Schweingruber. 2000. Gene sam1 encoding adenosylmethionine synthetase: effects of its expression in the fission yeast Schizosaccharomyces pombe. Yeast 16:1-10.
12. Horikawa, S., M. Ishikawa, H. Ozasa, and K. Tsukada. 1989. Isolation of a cDNA encoding the rat liver S-adenosylmethionine synthetase. Eur. J. Biochem. 184:497-501.
13. Horikawa, S., and K. Tsukada. 1991. Molecular cloning and nucleotide sequence of cDNA encoding the human liver S-adenosylmethionine synthetase. Biochem. Int. 25:81-90.
14. Keely, S. P., J. M. Fischer, M. T. Cushion, and J. R. Stringer. 2004. Phylogenetic identification of Pneumocystis murina sp. nov., a new species in laboratory mice. Microbiology 150:1153-1165.
15. Kotb, M., and A. M. Geller. 1993. Methionine adenosyltransferase: structure and function. Pharmacol. Ther. 59:125-143.
16. Kovacs, J. A., J. L. Halpern, J. C. Swan, J. Moss, J. E. Parrillo, and H. Masur. 1988. Identification of antigens and antibodies specific for Pneumocystis carinii. J. Immunol. 140:2023-2031.
17. Kutty, G., and J. A. Kovacs. 2007. Identification and characterization of rad51 of Pneumocystis. Gene 389:204-211.
18. Lopez-Vara, M. C., M. Gasset, and M. A. Pajares. 2000. Refolding and characterization of rat liver methionine adenosyltransferase from Escherichia coli inclusion bodies. Protein Expr. Purif. 19:219-226.
19. Lu, S. C. 2000. S-adenosylmethionine. Int. J. Biochem. Cell. Biol. 32:391-395.
20. Ma, L., L. Borio, H. Masur, and J. A. Kovacs. 1999. Pneumocystis carinii dihydropteroate synthase but not dihydrofolate reductase gene mutations correlate with prior trimethoprim-sulfamethoxazole or dapsone use. J. Infect. Dis. 180:1969-1978.
21. Markham, G. D., J. DeParasis, and J. Gatmaitan. 1984. The sequence of metK, the structural gene for S-adenosylmethionine synthetase in Escherichia coli. J. Biol. Chem. 259:14505-14507.
22. Masur, H., M. A. Michelis, J. B. Greene, I. Onorato, R. A. Stouwe, R. S. Holzman, G. Wormser, L. Brettman, M. Lange, H. W. Murray, and S. Cunningham-Rundles. 1981. An outbreak of community-acquired Pneumocystis carinii pneumonia: initial manifestation of cellular immune dysfunction. N. Engl. J. Med. 305:1431-1438.
23. Mei, Q., Q. Wang, W. Fan, B. Li, Y. Chen, and Y. Liu. 1994. Experimental and clinical study on pneumocystosis. III. Development and characterization of monoclonal antibody against Pneumocystis carinii. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Zuzhi. 12:188-191. (In Chinese.)
24. Merali, S., and A. B. Clarkson, Jr. 2004. S-adenosylmethionine and Pneumocystis. FEMS Microbiol. Lett. 237:179-186.
25. Merali, S., U. Frevert, J. H. Williams, K. Chin, R. Bryan, and A. B. Clarkson, Jr. 1999. Continuous axenic cultivation of Pneumocystis carinii. Proc. Natl. Acad. Sci. USA 96:2402-2407.
26. Merali, S., D. Vargas, M. Franklin, and A. B. Clarkson, Jr. 2000. S-adenosylmethionine and Pneumocystis carinii. J. Biol. Chem. 275:14958-14963.
27. Munoz, A., L. K. Schrager, H. Bacellar, I. Speizer, S. H. Vermund, R. Detels, A. J. Saah, L. A. Kingsley, D. Seminara, and J. P. Phair. 1993. Trends in the incidence of outcomes defining acquired immunodeficiency syndrome (AIDS) in the Multicenter AIDS Cohort Study: 1985-1991. Am. J. Epidemiol. 137:423-438.
28. Perez-Pertejo, Y., R. M. Reguera, C. Garcia-Estrada, R. Balana-Fouce, and D. Ordonez. 2004. Mutational analysis of methionine adenosyltransferase from Leishmania donovani. Eur. J. Biochem. 271:2791-2798.
29. Perez-Pertejo, Y., R. M. Reguera, H. Villa, C. Garcia-Estrada, R. Balana-Fouce, M. A. Pajares, and D. Ordonez. 2003. Leishmania donovani methionine adenosyltransferase. Role of cysteine residues in the recombinant enzyme. Eur. J. Biochem. 270:28-35.
30. Sakata, S. F., L. L. Shelly, S. Ruppert, G. Schutz, and J. Y. Chou. 1993. Cloning and expression of murine S-adenosylmethionine synthetase. J. Biol. Chem. 268:13978-13986.
31. Sinclair, K., A. E. Wakefield, S. Banerji, and J. M. Hopkin. 1991. Pneumocystis carinii organisms derived from rat and human hosts are genetically distinct. Mol. Biochem. Parasitol. 45:183-184.
32. Stringer, J. R., C. B. Beard, R. F. Miller, and A. E. Wakefield. 2002. A new name (Pneumocystis jirovecii) for Pneumocystis from humans. Emerg. Infect. Dis. 8:891-896.
33. Stringer, J. R., S. L. Stringer, J. Zhang, R. Baughman, A. G. Smulian, and M. T. Cushion. 1993. Molecular genetic distinction of Pneumocystis carinii from rats and humans. J. Eukaryot. Microbiol. 40:733-741.
34. Taylor, J. C., and G. D. Markham. 2000. The bifunctional active site of S-adenosylmethionine synthetase. Roles of the basic residues. J. Biol. Chem. 275:4060-4065.
35. Thomas, D., R. Rothstein, N. Rosenberg, and Y. Surdin-Kerjan. 1988. SAM2 encodes the second methionine S-adenosyl transferase in Saccharomyces cerevisiae: physiology and regulation of both enzymes. Mol. Cell. Biol. 8:5132-5139.
36. Thomas, D., and Y. Surdin-Kerjan. 1987. SAM1, the structural gene for one of the S-adenosylmethionine synthetases in Saccharomyces cerevisiae. Sequence and expression. J. Biol. Chem. 262:16704-16709.
37. Wright, T. W., T. Y. Bissoondial, C. G. Haidaris, F. Gigliotti, and P. J. Haidaris. 1995. Isoform diversity and tandem duplication of the glycoprotein A gene in ferret Pneumocystis carinii. DNA Res. 2:77-88.