Expression of variants of the major surface glycoprotein of Pneumocystis carinii

Journal of Experimental Medicine

Volumn 183, Issue 3, 1996, Pages 1229-1234

  Angus, C William ^a   Tu, Alex ^a   Vogel, Peter ^b   Qin, Mei ^a   Kovacs, Joseph A ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; GLYCOPROTEIN;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIGENIC VARIATION; ARTICLE; GENE EXPRESSION; HOST RESISTANCE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MALE; MULTIGENE FAMILY; NONHUMAN; PNEUMOCYSTIS CARINII; PRIORITY JOURNAL; RAT; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; FUNGAL PROTEINS; GENE EXPRESSION; GENES, BACTERIAL; IMMUNE SERA; LUNG; MALE; MEMBRANE GLYCOPROTEINS; MICE; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; PEPTIDES; PNEUMOCYSTIS; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; VARIATION (GENETICS);

EID: 0029669951     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.183.3.1229     Document Type: Article

References (27)

1. Masur, H., M.A. Michelis, J.B. Greene, I. Onorato, R.A. Stouwe, R.S. Holzman, G. Wormser, L. Brettman, M. Lange, H.W. Murray, and S. Cunningham-Rundles. 1981. An outbreak of community-acquired Pneumocystis carinii pneumonia: initial manifestation of cellular immune dysfunction. N. Engl. J Med. 305:1431-1438.
2. Munoz, A., L.K. Schrager, H. Bacellar, I. Speizer, S.H. Vermund, R. Detels, A.J. Saah, L.A. Kingsley, D. Seminara, and J P. Phair. 1993. Trends in the incidence of outcomes defining acquired immunodeficiency syndrome (AIDS) in the Multicenter AIDS Cohort Study: 1985-1991. Am. J. Epidemiol 137:423-438.
3. Edman, J.C., J.A. Kovacs, H. Masur, D.V. Santi, H.J. Elwood, and M.L. Sogin. 1988. Ribosomal RNA sequence shows Pneumocystis carinii to be a member of the Fungi. Nature (Lond.). 334:519-522.
4. Gigliotti, F., L.R. Ballou, W.T. Hughes, and B.D. Mosley. 1988. Purification and initial characterization of a ferret Pneumocystis carinii surface antigen. J. Infect. Dis. 158:848-854.
5. Lundgren, B., G.Y. Lipschik, and J.A. Kovacs. 1991. Purification and characterization of a major human Pneumocystis carinii surface antigen. J. Clin. Invest. 87:163-170.
6. Radding, J.A., M.Y. Armstrong, R. Ullu, and F.F. Richards. 1989. Identification and isolation of a major cell surface glycoprotein of Pneumocystis carinii. Infect. Immun. 57:2149-2157.
7. Gigliotti, F. 1992. Host species-specific antigenic variation of a mannosylated surface glycoprotein of Pneumocystis carinii. J. Infect. Dis. 165:329-336.
8. Kovacs, J.A., F. Powell, J.C. Edman, B. Lundgren, A. Martinez, B. Drew, and C.W. Angus. 1993. Multiple genes encode the major surface glycoprotein of Pneumocystis carinii. J. Biol. Chem. 268:6034-6040.
9. Stringer, S.L., T. Garbe, S.M. Sunkin, and J.R. Stringer. 1993. Genes encoding antigenic surface glycoproteins in Pneumocystis from humans. J Eukaryot. Microbiol 40:821-826.
10. Haidans, P.J., T.W. Wright, F. Gigliotti, and C.G. Haidaris. 1992. Expression and characterization of a cDNA clone encoding an immunodominant surface glycoprotein of Pneumocystis carinii. J. Infect. Dis. 166:1113-1123.
11. Sunkin, S.M., S.L. Stringer, and J.R. Stringer. 1994. A tandem repeat of rat-derived Pneumocystis carinii genes encoding the major surface glycoprotein. J. Eukaryot. Microbiol. 41:292-300.
12. Angus, C.W., M. Nam, R. Turner, P. Vogel, and J. Kovacs. 1994. Antigenic variation in the major surface glycoprotein of Pneumocystis carinii. In Molecular Approaches to the Control of Infectious Diseases, R.M. Chanock, H.S. Ginsberg, F. Brown, and E. Norrby, editors. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY. 41.
13. Wada, M., S.M. Sunkim, J.R. Stringer, and Y. Nakamura. 1995. Antigenic variation by positional control of major surface glycoprotein expression in Pneumocystis carinii. J. Infect. Dis. 171:1563-1568.
14. Pottratz, S.T., J. Paulstrud, J.S. Smith, and W.J.D. Martin. 1991. Pneumocystis carinii attachment to cultured lung cells by Pneumocystis gp 120, a fibronectin binding protein. J. Clin. Invest. 88:403-407.
15. Ezekowitz, R.A., D.J. Williams, H. Koziel, M.Y. Armstrong, A. Warner, F.F. Richards, and R.M. Rose. 1991. Uptake of Pneumocystis carinii mediated by the macrophage mannose receptor. Nature (Lond.). 351:155-158.
16. Zimmerman, P.E., D.R. Voelker, F.X. McCormack, J.R. Paulsrud, and W.J.D. Martin. 1992. 120-kD surface glycoprotein of Pneumocystis carinii is a ligand for surfactant protein A. J. Clin. Invest. 89:143-149.
17. Limper, A.H., J.E. Standing, O.A. Hoffman, M. Castro, and L.W. Neese. 1993. Fibronectin binds to Pneumocystis carinii and mediates organism attachment to cultured lung epithelial cells. Infect. Immun. 61:4302-4309.
18. Lundgren, B., J.D. Lundgren, T. Nielsen, L. Mathiesen, J.O. Nielsen, and J.A. Kovacs. 1992. Antibody responses to a major Pneumocystis carinii antigen in human immunodeficiency virus-infected patients with and without P. carinii pneumonia. J. Infect. Dis. 165:1151-1155.
19. Theus, S.A., R.P. Andrews, P. Steele, and P.D. Walzer. 1995. Adoptive transfer to lymphocytes sensitized to the major surface glycoprotein of Pneumocystis carinii confers protection in the rat. J. Clin. Invest. 95:2587-2593.
20. Linke, M.J., A.G. Smulian, J.R. Stringer, and P.D. Walzer. 1994. Characterization of multiple unique cDNAs encoding the major surface glycoprotein of rat-derived Pneumocystis carinii. Parasitol. Res. 80:478-486.
21. Kovacs, J.A., J.L. Halpern, J.C. Swan, J. Moss, J.E. Parillo, and H. Masur. 1988. Monoclonal antibodies to Pneumocystis carinii: identification of specific antigens and characterization of antigenic differences between rat and human isolates. J. Infect. Dis. 159:60-70.
22. Cushion, M.T., J.A. DeStefano, and P.D. Walzer. 1988. Pneumocystis carinii: surface reactive carbohydrates detected by lectin probes. Exp. Parasitol. 67:136-147.
23. Mei, Q., Q.N. Wang, W.K. Fan, B.R. Li, Y.T. Chen, and Y.H. Liu. 1994. Experimental and clinical study on Pneumocystis. III. development and characterization of monoclonal antibody against Pneumocystis carinii. Chi. J. Parasitol. Parasitic Dis. 12:188-191.
24. Walzer, P.D., M.E. Rutledge, K. Yoneda, and E.V. Stahr. 1979. Pneumocystis carinii: new separations methods from lung tissue. Exp. Parasitol. 47:356-368.
25. Cushion, M.T., J. Zhang, M. Kaselis, D. Giuntoli, S.L. Stringer, and J.R. Stringer. 1993. Evidence for two genetic variants of Pneumocystis carinii coinfecting laboratory rats. J. Clin. Microbiol. 31:1217-1223.
26. Hong, S.T., P.E. Steele, M.T. Cushion, P.D. Walzer, S.L. Stringer, and J.R. Stringer. 1990. Pneumocystis carinii karyotypes.J. Clin. Microbiol. 28:1785-1795.
27. Donelson, J.E. 1995. Mechanisms of antigenic variation in Borrelia hermsii and African trypanosomes. J. Biol. Chem. 270: 7783-7786.