c-kit is required for cardiomyocyte terminal differentiation

Circulation Research

Volumn 102, Issue 6, 2008, Pages 677-685

  Li, Ming ^a   Naqvi, Nawazish ^a   Yahiro, Eiji ^a   Liu, Ke ^a   Powell, Pamela C ^b   Bradley, Wayne E ^b   Martin, David I K ^c   Graham, Robert M ^d   Dell'Italia, Louis J ^a,b,e   Husain, Ahsan ^a,b,f  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b University of Alabama at Birmingham   (United States)

^c CHILDREN S HOSPITAL OAKLAND RESEARCH INSTITUTE   (United States)

^d VICTOR CHANG CARDIAC RESEARCH INSTITUTE   (Australia)

^e BMR2 435 ^*  (United States)

^f UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

c kit; Cardiac stem cells; Cardiomyocyte; Pressure overload; Terminal differentiation

Indexed keywords

STEM CELL FACTOR RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CYCLE; CELL DIFFERENTIATION; CELL HYPERPLASIA; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; GENE MUTATION; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE HYPERTROPHY; HEART MUSCLE CELL; MALE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; STEM CELL; WILD TYPE;

AGING; ANIMALS; ANIMALS, NEWBORN; AORTA; BLOOD PRESSURE; CELL CYCLE; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOTYPE; HEART VENTRICLES; HYPERTROPHY, LEFT VENTRICULAR; LIGATION; MALE; MICE; MICE, KNOCKOUT; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; PHENOTYPE; PROTO-ONCOGENE PROTEINS C-KIT; RNA, MESSENGER; STEM CELLS; TIME FACTORS; VENTRICULAR FUNCTION, LEFT;

EID: 41449111037     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.107.161737     Document Type: Article

References (30)

1. Rubart M, Field LJ. Cardiac regeneration: repopulating the heart. Annu Rev Physiol. 2006;68:29-49.
2. MacLellan WR, Schneider MD. Genetic dissection of cardiac growth control pathways. Annu Rev Physiol. 2000;62:289-313.
3. Jessup M, Brozena S. Heart failure. N Engl J Med. 2003;348:2007-2018.
4. Beltrami AP, Barlucchi L, Torella D, Baker M, Limana F, Chimenti S, Kasahara H, Rota M, Musso E, Urbanek K, Leri A, Kajstura J, Nadal-Ginard B, Anversa P. Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell. 2003;114:763-776.
5. Hsieh PC, Segers VF, Davis ME, MacGillivray C, Gannon J, Molkentin JD, Robbins J, Lee RT. Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury. Nat Med. 2007;13:970-974.
6. Linke A, Müller P, Nurzynska D, Casarsa C, Torella D, Nascimbene A, Castaldo C, Cascapera S, Böhm M, Quaini F, Urbanek K, Leri A, Hintze TH, Kajstura J, Anversa P. Stem cells in the dog heart are self-renewing, clonogenic, and multipotent and regenerate infarcted myocardium, improving cardiac function. Proc Natl Acad Sci U S A. 2005;102:8966-8971.
7. Blume-Jensen P, Hunter T. Oncogenic kinase signalling. Nature. 2001;411:355-365.
8. Herbst R, Shearman MS, Obermeier A, Schlessinger J, Ullrich A. Differential effects of W mutations on p145c-kit tyrosine kinase activity and substrate interaction. J Biol Chem. 1992;267:13210-13216.
9. Galli SJ, Kitamura Y. Genetically mast-cell-deficient W/Wv and Sl/Sld mice. Their value for the analysis of the roles of mast cells in biologic responses in vivo. Am J Pathol. 1987;127:191-198.
10. Ohta H, Yomogida K, Dohmae K, Nishimune Y. Regulation of proliferation and differentiation in spermatogonial stem cells: the role of c-kit and its ligand SCF. Development. 2000;127:2125-2131.
11. v, W41 and W. EMBO J. 1990;9:1805-1813.
12. Soonpaa MH, Kim KK, Pjak L, Franklin M, Field LJ. Cardiomyocyte DNA synthesis and binucleation during murine development. Am J Physiol. 1996;271:H2183-H2189.
13. + cells are from the bone marrow and regulate the myocardial balance of angiogenic cytokines. J Clin Invest. 2006;116:1865-1877.
14. Soonpaa MH, Koh GY, Pajak L, Jing S, Wang H, Franklin MT, Kim KK, Field LJ. Cyclin D1 overexpression promotes cardiomyocyte DNA synthesis and multinucleation in transgenic mice. J Clin Invest. 1997;99:2644-2654.
15. Kühn B, del Monte F, Hajjar RJ, Chang YS, Lebeche D, Arab S, Keating MT. Periostin induces proliferation of differentiated cardiomyocytes and promotes cardiac repair. Nat Med. 2007;13:962-969.
16. Du XJ, Fang L, Gao XM, Kiriazis H, Feng X, Hotchkin E, Finch AM, Chaulet H, Graham RM. Genetic enhancement of ventricular contractility protects against pressure-overload-induced cardiac dysfunction. J Mol Cell Cardiol. 2004;37:979-987.
17. Andersen CB, Ladefoged SD, Larsen S. Acute kidney graft rejection. A morphological and immunohistological study on "zero-hour" and follow-up biopsies with special emphasis on cellular infiltrates and adhesion molecules. APMIS. 1994;102:23-37.
18. Chen R, Ning G, Zhao ML, Fleming MG, Diaz LA, Werb Z, Liu Z. Mast cells play a key role in neutrophil recruitment in experimental bullous pemphigoid. J Clin Invest. 2001;108:1151-1158.
19. Limana F, Zacheo A, Mocini D, Mangoni A, Borsellino G, Diamantini A, De Mori R, Battistini L, Vigna E, Santini M, Loiaconi V, Pompilio G, Germani A, Capogrossi MC. Identification of myocardial and vascular precursor cells in human and mouse epicardium. Circ Res. 2007;101:1255-1265.
20. Anversa P, Kajstura J, Leri A, Boli R. Life and death of cardiac stem cells: a paradigm shift in cardiac biology. Circulation. 2006;113:1451-1463.
21. Morrison SJ, Kimble J. Asymmetric and symmetric stem-cell divisions in development and cancer. Nature. 2006;441:1068-1074.
22. Matz DG, Oberpriller JO, Oberpriller JC. Comparison of mitosis in binucleated and mononucleated newt cardiac myocytes. Anat Rec. 1998;251:245-255.
23. Soonpaa MH, Field LJ. Survey of studies examining mammalian cardiomyocyte DNA synthesis. Circ Res. 1998;83:15-26.
24. Cheng RK, Asai T, Tang H, Dashoush NH, Kara RJ, Costa KD, Naka Y, Wu EX, Wolgemuth DJ, Chaudhry HW. Cyclin A2 induces cardiac regeneration after myocardial infarction and prevents heart failure. Circ Res. 2007;100:1741-1748.
25. KIP1 knockout mice. Circ Res. 1999;85:117-127.
26. Pasumarthi KB, Field LJ. Cardiomyocyte cell cycle regulation. Circ Res. 2002;90:1044-1054.
27. Clark EB, Hu N, Frommelt P, Vandekieft GK, Dummett JL, Tomanek RJ. Effect of increased pressure on ventricular growth in stage 21 chick embryos. Am J Physiol. 1989;257:H55-H61.
28. Nakajima H, Nakajima HO, Tsai SC, Field LJ. Expression of mutant p193 and p53 permits cardiomyocyte cell cycle reentry after myocardial infarction in transgenic mice. Circ Res. 2004;94:1606-1614.
29. Anversa P. Aging and longevity: the IGF-1 enigma. Circ Res. 2005;97:411-414.
30. Dawn B, Guo Y, Rezazadeh A, Huang Y, Stein AB, Hunt G, Tiwari S, Varma J, Gu Y, Prabhu SD, Kajstura J, Anversa P, Ildstad ST, Bolli R. Postinfarct cytokine therapy regenerates cardiac tissue and improves left ventricular function. Circ Res. 2006;98:1098-1105.