Mitosis: Moesin and the Importance of Being Round

Current Biology

Volumn 18, Issue 7, 2008, Pages

  Rosenblatt, Jody ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; DROSOPHILA PROTEIN; MEMBRANE PROTEIN; MOESIN, DROSOPHILA; PROTEIN SERINE THREONINE KINASE; SLIK PROTEIN, DROSOPHILA; UNCLASSIFIED DRUG;

ANIMAL; CELL LINE; CELL SHAPE; CYTOSKELETON; DROSOPHILA; METABOLISM; MITOSIS; PHOSPHORYLATION; PHYSIOLOGY; SHORT SURVEY;

ACTINS; ANIMALS; CELL LINE; CELL SHAPE; CYTOSKELETON; DROSOPHILA; DROSOPHILA PROTEINS; MEMBRANE PROTEINS; MITOSIS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES;

EID: 41449088027     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2008.02.013     Document Type: Short Survey

References (13)

1. Kunda P., Pelling A.E., Liu T., and Baum B. Moesin controls cortical rigidity, cell rounding, and spindle morphogenesis during mitosis. Curr. Biol. 18 (2008) 91-101
2. Carreno S., Kouranti I., Glusman E.S., Fuller M.T., Echard A., and Payre F. Moesin and its activating kinase Slik are required for cortical stability and microtubule organization in mitotic cells. J. Cell Biol. 180 (2008) 739-746
3. Hipfner D.R., Keller N., and Cohen S.M. Slik Sterile-20 kinase regulates Moesin activity to promote epithelial integrity during tissue growth. Genes Dev. 18 (2004) 2243-2248
4. Pearson M.A., Reczek D., Bretscher A., and Karplus P.A. Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain. Cell 101 (2000) 259-270
5. Hughes S.C., and Fehon R.G. Understanding ERM proteins - the awesome power of genetics finally brought to bear. Curr. Opin. Cell Biol. 19 (2007) 51-56
6. Maddox A.S., and Burridge K. RhoA is required for cortical retraction and rigidity during mitotic cell rounding. J. Cell Biol. 160 (2003) 255-265
7. Rosenblatt J., Cramer L.P., Baum B., and McGee K.M. Myosin II-dependent cortical movement is required for centrosome separation and positioning during mitotic spindle assembly. Cell 117 (2004) 361-372
8. Lansbergen G., Grigoriev I., Mimori-Kiyosue Y., Ohtsuka T., Higa S., Kitajima I., Demmers J., Galjart N., Houtsmuller A.B., Grosveld F., et al. CLASPs attach microtubule plus ends to the cell cortex through a complex with LL5beta. Dev. Cell 11 (2006) 21-32
9. Mimori-Kiyosue Y., and Tsukita S. "Search-and-capture" of microtubules through plus-end-binding proteins (+TIPs). J. Biochem. 134 (2003) 321-326
10. Speck O., Hughes S.C., Noren N.K., Kulikauskas R.M., and Fehon R.G. Moesin functions antagonistically to the Rho pathway to maintain epithelial integrity. Nature 421 (2003) 83-87
11. Mills J.C., Stone N.L., Erhardt J., and Pittman R.N. Apoptotic membrane blebbing is regulated by myosin light chain phosphorylation. J. Cell Biol. 140 (1998) 627-636
12. Coleman M.L., Sahai E.A., Yeo M., Bosch M., Dewar A., and Olson M.F. Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I. Nat. Cell Biol. 3 (2001) 339-345
13. Charafe-Jauffret E., Ginestier C., Monville F., Finetti P., Adelaide J., Cervera N., Fekairi S., Xerri L., Jacquemier J., Birnbaum D., et al. Gene expression profiling of breast cell lines identifies potential new basal markers. Oncogene 25 (2006) 2273-2284