Chronic hypoxia induces nonreversible right ventricle dysfunction and dysplasia in rats

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 287, Issue 3 56-3, 2004, Pages

  Bonnet, Pierre ^a,c   Bonnet, Sébastien ^a   Boissière, Julien ^a,c   Le Net, Jean Loïc ^b   Gautier, Mathieu ^a,c   De La Roque, Eric Dumas ^a   Eder, Véronique ^a,c  

^a UNIVERSITÉ DE TOURS   (France)

^b PFIZER INC   (United States)

^c Institut Fedirati de Recherche 135   (France)

Author keywords

Echocardiography; Pulmonary hypertension; Remodelling

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOPPLER ECHOCARDIOGRAPHY; DYSPLASIA; HEART MUSCLE ISCHEMIA; HEART RIGHT VENTRICLE FAILURE; HEART VENTRICLE CONTRACTILITY; HEART VENTRICLE REMODELING; HEART VENTRICLE WALL; HISTOPATHOLOGY; HYPOBARISM; ISOLATED HEART; LUNG ARTERY PRESSURE; LUNG BLOOD FLOW; M MODE ECHOCARDIOGRAPHY; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RAT;

ANIMALS; ANOXIA; CHRONIC DISEASE; DIASTOLE; ECHOCARDIOGRAPHY; HYPERTENSION, PULMONARY; MALE; MYOCARDIUM; RATS; RATS, WISTAR; SYSTOLE; VENTRICULAR DYSFUNCTION, RIGHT;

EID: 4143149545     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00802.2003     Document Type: Article

References (19)

1. Bjornerheim R, Grogaard HK, Kjekshus H, Attramadal H, and Smiseth OA. High frame rate Doppler echocardiography in the rat: an evaluation of the method. Eur J Echocardiogr 2: 78-87, 2001.
2. Bonnet S, Dubuis E, Vandier C, Martin S, Marthan R, and Savineau JP. Reversal of chronic hypoxia-induced alterations in pulmonary artery smooth muscle electromechanical coupling upon air breathing. Cardiovasc Res 53: 1019-1028, 2002.
3. Burgess MI, Bright-Thomas RJ, and Ray SG. Echocardiographic evaluation of right ventricular function. Eur J Echocardiogr 3: 252-262, 2002.
4. Callens-elAmrani F, Snoeckx L, and Swynghedauw B. Anoxia-induced changes in ventricular diastolic compliance in two models of hypertension in rats. J Hypertens 10: 229-236, 1992.
5. Caso P, Galderisi M, Cicala S, Cioppa C, D'Andrea A, Lagioia G, Liccardo B, Martiniello AR, and Mininni N. Association between myocardial right ventricular relaxation time and pulmonary arterial pressure in chronic obstructive lung disease: analysis by pulsed Doppler tissue imaging. J Am Soc Echocardiogr 14: 970-977, 2001.
6. Cicala S, Galderisi M, Caso P, Petrocelli A, D'Errico A, de Divitiis O, and Calabro R. Right ventricular diastolic dysfunction in arterial systemic hypertension: analysis by pulsed tissue Doppler. Eur J Echocardiogr 3: 135-142, 2002.
7. Davie NJ, Crossno JT, Frid MG, Hofmeister SE, Reeves JT, Hyde DM, Carpenter TC, Brunetti JA, McNiece IK, and Stenmark KR. Hypoxia-induced pulmonary artery adventitial remodeling and neovascularization: potential contribution of circulating progenitor cells. Am J Physiol Lung Cell Mol Physiol 286: L668-L678, 2004.
8. Fontaliran F, Arkwright S, Vilde F, and Fontaine G. Arrhythmogenic right ventricular dysplasia and cardiomyopathy. Clinical and anatomicpathologic aspects, nosologic approach. Arch Anat Cytol Pathol 46: 171-177, 1998.
9. Galderisi M, Severino S, Caso P, Cicala S, Petrocelli A, De Simone L, Mininni N, and de Divitiis O. Right ventricular myocardial diastolic dysfunction in different kinds of cardiac hypertrophy: analysis by pulsed Doppler tissue imaging. Ital Heart J 2: 912-920, 2001.
10. Harada K, Tamura M, Toyono M, and Yasuoka K. Comparison of the right ventricular Tei index by tissue Doppler imaging to that obtained by pulsed Doppler in children without heart disease. Am J Cardiol 90: 566-569, 2002.
11. Jones JE, Mendes L, Rudd MA, Russo G, Loscalzo J, and Zhang YY. Serial noninvasive assessment of progressive pulmonary hypertension in a rat model. Am J Physiol Heart Circ Physiol 283: H364-H371, 2002.
12. Litwin SE, Katz SE, Morgan JP, and Douglas PS. Serial echocardiographic assessment of left ventricular geometry and function after large myocardial infarction in the rat. Circulation 89: 345-354, 1994.
13. Mattioli AV, Vandelli R, and Mattioli G. Doppler echocardiographic evaluation of right ventricular function in patients with right ventricular infarction. J Ultrasound Med 19: 831-836, 2000.
14. Menzel T, Kramm T, Bruckner A, Mohr-Kahaly S, Mayer E, and Meyer J. Quantitative assessment of right ventricular volumes in severe chronic thromboembolic pulmonary hypertension using transthoracic three-dimensional echocardiography: changes due to pulmonary thromboendarterectomy. Eur J Echocardiogr 3: 67-72, 2002.
15. Myslinski W, Mosiewicz J, Makaruk B, Ostrowski S, and Hanzlik J. Echocardiographic evaluation of right ventricular structure and diastolic function in patients with overweight and arterial hypertension. Wiad Lek 55: 56-63, 2002.
16. Nakamura K, Miyahara Y, Ikeda S, and Naito T. Assessment of right ventricular diastolic function by pulsed Doppler echocardiography in chronic pulmonary disease and pulmonary thromboembolism. Respiration 62: 237-243, 1995.
17. Novotna J and Herget J. Exposure to chronic hypoxia induces qualitative changes of collagen in the walls of peripheral pulmonary arteries. Life Sci 62: 1-12, 1998.
18. Olivetti G, Ricci R, Lagrasta C, Maniga E, Sonnenblick EH, and Anversa P. Cellular basis of wall remodeling in long-term pressure overload-induced right ventricular hypertrophy in rats. Circ Res 63: 648-657, 1988.
19. Olschewski H and Seeger W. Pathophysiology of pulmonary hypertension. Z Kardiol 83: 181-191, 1994.