Carbamoylphosphonate MMP inhibitors. Part 4: The influence of chirality and geometrical isomerism on the potency and selectivity of inhibition

Tetrahedron Asymmetry

Volumn 15, Issue 15, 2004, Pages 2415-2420

  Breuer, Eli ^a   Katz, Yiffat ^a   Hadar, Rivka ^a   Reich, Reuven ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

DIETHYL (2 NORBORNYL)CARBAMOYLPHOSPHONIC ACID; DIETHYL N (1 CYCLOHEXYLETHYL)CARBAMOYLPHOSPHONATE; DIETHYL N (2 BUTYL)CARBAMOYLPHOSPHONATE; DIETHYL N (4 METHYLCYCLOHEXYL)CARBAMOYLPHOSPHONATE; GELATINASE A; GELATINASE B; INTERSTITIAL COLLAGENASE; MATRIX METALLOPROTEINASE INHIBITOR; N (1 CYCLOHEXYLETHYL)CARBAMOYLPHOSPHINIC ACID; N (2 NORBORNYL)CARBAMOYLPHOSPHONIC ACID; N (4 METHYLCYCLOHEXYL)CARBAMOYLPHOSPHONIC ACID; N 2 BUTYLCARBAMOYLPHOSPHONIC ACID; NEUTROPHIL COLLAGENASE; PHOSPHINIC ACID DERIVATIVE; RECOMBINANT ENZYME; STROMELYSIN; UNCLASSIFIED DRUG;

ARTICLE; CHIRALITY; DRUG POTENCY; DRUG SELECTIVITY; ENANTIOMER; IC 50; ISOMERISM; PRIORITY JOURNAL; STEREOISOMERISM;

EID: 4143137943     PISSN: 09574166     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetasy.2004.07.002     Document Type: Article

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