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Volumn 22, Issue 15, 2004, Pages 3016-3022

Preoperative uracil, tegafur, and concomitant radiotherapy in operable rectal cancer: A phase II multicenter study with 3 years' follow-up

Author keywords

[No Author keywords available]

Indexed keywords

FLUOROURACIL; FOLINIC ACID; UFT; 1 UFT PROTOCOL; 1-UFT PROTOCOL; ANTINEOPLASTIC AGENT; TEGAFUR; URACIL;

EID: 4143132330     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.2004.11.124     Document Type: Article
Times cited : (70)

References (30)
  • 1
    • 0020393438 scopus 로고
    • Pharmacologic requirements for obtaining sensitization of human tumor cells in vitro to combined 5-fluorouracil or ftorafur and X rays
    • Byfield JE, Calabro-Jones P, Klisak I, et al: Pharmacologic requirements for obtaining sensitization of human tumor cells in vitro to combined 5-fluorouracil or ftorafur and X rays. Int J Radiat Oncol Biol Phys 8:1923-1933, 1982
    • (1982) Int J Radiat Oncol Biol Phys , vol.8 , pp. 1923-1933
    • Byfield, J.E.1    Calabro-Jones, P.2    Klisak, I.3
  • 2
    • 0026028777 scopus 로고
    • 5-Fluorouracil modulation of radiosensitivity in cultured human carcinoma cells
    • Smalley SR, Kimler BF, Evans RG: 5-Fluorouracil modulation of radiosensitivity in cultured human carcinoma cells. Int J Radiat Oncol Biol Phys 20:207-211, 1991
    • (1991) Int J Radiat Oncol Biol Phys , vol.20 , pp. 207-211
    • Smalley, S.R.1    Kimler, B.F.2    Evans, R.G.3
  • 3
    • 0028136295 scopus 로고
    • Improving adjuvant therapy for rectal cancer by combining protracted-infusion fluorouracil with radiation therapy after curative surgery
    • O'Connell MJ, Martenson JA, Wieand HS, et al: Improving adjuvant therapy for rectal cancer by combining protracted-infusion fluorouracil with radiation therapy after curative surgery. N Engl J Med 331:502-507, 1994
    • (1994) N Engl J Med , vol.331 , pp. 502-507
    • O'Connell, M.J.1    Martenson, J.A.2    Wieand, H.S.3
  • 4
    • 3042760073 scopus 로고    scopus 로고
    • Intergroup 0144 - Phase III trial of 5-FU based chemotherapy regimens plus radiotherapy (XRT) in postoperative adjuvant rectal cancer: Bolus 5-FU vs prolonged venous infusion (PVI) before and after XRT + PVI vs bolus 5-FU + leucovorin (LV) + levamisole (LEV) before and after XRT + bolus 5-FU + LV
    • abstr 1006
    • Smalley SR, Benedetti J, Williamson S, et al: Intergroup 0144 - phase III trial of 5-FU based chemotherapy regimens plus radiotherapy (XRT) in postoperative adjuvant rectal cancer: Bolus 5-FU vs prolonged venous infusion (PVI) before and after XRT + PVI vs bolus 5-FU + leucovorin (LV) + levamisole (LEV) before and after XRT + bolus 5-FU + LV. Proc Am Soc Clin Oncol 22:251, 2003 (abstr 1006)
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 251
    • Smalley, S.R.1    Benedetti, J.2    Williamson, S.3
  • 5
    • 0029093508 scopus 로고
    • Preoperative infusional chemoradiation therapy for stage T3 rectal cancer
    • Rich TA, Skibber JM, Ajani JA, et al: Preoperative infusional chemoradiation therapy for stage T3 rectal cancer. Int J Radiat Oncol Biol Phys 32:1025-1029, 1995
    • (1995) Int J Radiat Oncol Biol Phys , vol.32 , pp. 1025-1029
    • Rich, T.A.1    Skibber, J.M.2    Ajani, J.A.3
  • 6
    • 0035143630 scopus 로고    scopus 로고
    • Radiotherapy, concomitant protracted-venous-infusion 5-fluorouracil, and surgery for ultrasound-staged T3 or T4 rectal cancer
    • Mehta VK, Poen J, Ford J, et al: Radiotherapy, concomitant protracted-venous-infusion 5-fluorouracil, and surgery for ultrasound-staged T3 or T4 rectal cancer. Dis Colon Rectum 44:52-58, 2001
    • (2001) Dis Colon Rectum , vol.44 , pp. 52-58
    • Mehta, V.K.1    Poen, J.2    Ford, J.3
  • 7
    • 0033984573 scopus 로고    scopus 로고
    • Preoperative radiochemotherapy in rectal cancer: Long-term results of a phase II trial
    • Bosset JF, Magnin V, Maingon P, et al: Preoperative radiochemotherapy in rectal cancer: Long-term results of a phase II trial. Int J Radiat Oncol Biol Phys 46:323-327, 2000
    • (2000) Int J Radiat Oncol Biol Phys , vol.46 , pp. 323-327
    • Bosset, J.F.1    Magnin, V.2    Maingon, P.3
  • 8
    • 0035869720 scopus 로고    scopus 로고
    • Preoperative combined modality therapy for clinically resectable uT3 rectal adenocarcinoma
    • Grann A, Feng C, Wong D, et al: Preoperative combined modality therapy for clinically resectable uT3 rectal adenocarcinoma. Int J Radiat Oncol Biol Phys 49:987-995, 2001
    • (2001) Int J Radiat Oncol Biol Phys , vol.49 , pp. 987-995
    • Grann, A.1    Feng, C.2    Wong, D.3
  • 9
    • 8044239624 scopus 로고    scopus 로고
    • A clinical trial to evaluate the worth of preoperative multimodality therapy in patients with operable carcinoma of the rectum: A progress report of National Surgical Breast and Bowel Project Protocol R-03
    • Hyams DM, Mamounas EP, Petrelli N, et al: A clinical trial to evaluate the worth of preoperative multimodality therapy in patients with operable carcinoma of the rectum: A progress report of National Surgical Breast and Bowel Project Protocol R-03. Dis Colon Rectum 40:131-139, 1997
    • (1997) Dis Colon Rectum , vol.40 , pp. 131-139
    • Hyams, D.M.1    Mamounas, E.P.2    Petrelli, N.3
  • 10
    • 0031691506 scopus 로고    scopus 로고
    • Comparison of 5-fluorouracil pharmacokinetics in patients receiving continuous 5-fluorouracil infusion and oral uracil plus N1-(2′- tetrahydrofuryl)-5-fluorouracil
    • Ho DH, Pazdur R, Covington W, et al: Comparison of 5-fluorouracil pharmacokinetics in patients receiving continuous 5-fluorouracil infusion and oral uracil plus N1-(2′-tetrahydrofuryl)-5-fluorouracil. Clin Cancer Res 4:2085-2088, 1998
    • (1998) Clin Cancer Res , vol.4 , pp. 2085-2088
    • Ho, D.H.1    Pazdur, R.2    Covington, W.3
  • 11
    • 0036731818 scopus 로고    scopus 로고
    • Multicenter phase III study of uracil/tegafur and oral leucovorin versus fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer
    • Douillard JY, Hoff PM, Skillings JR, et al: Multicenter phase III study of uracil/tegafur and oral leucovorin versus fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer. J Clin Oncol 20:3605-3616, 2002
    • (2002) J Clin Oncol , vol.20 , pp. 3605-3616
    • Douillard, J.Y.1    Hoff, P.M.2    Skillings, J.R.3
  • 12
    • 0036727089 scopus 로고    scopus 로고
    • Randomized comparative study of tegafur/uracil and oral leucovorin versus parenteral fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer
    • Carmichael J, Popiela T, Radstone D, et al: Randomized comparative study of tegafur/uracil and oral leucovorin versus parenteral fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer. J Clin Oncol 20:3617-3627, 2002
    • (2002) J Clin Oncol , vol.20 , pp. 3617-3627
    • Carmichael, J.1    Popiela, T.2    Radstone, D.3
  • 13
    • 0034667864 scopus 로고    scopus 로고
    • Phase I study of pre-operative oral uracil and tegafur plus leucovorin and radiation therapy in rectal cancer
    • Hoff PM, Janjan N, Saad ED, et al: Phase I study of pre-operative oral uracil and tegafur plus leucovorin and radiation therapy in rectal cancer. J Clin Oncol 18:3529-3534, 2000
    • (2000) J Clin Oncol , vol.18 , pp. 3529-3534
    • Hoff, P.M.1    Janjan, N.2    Saad, E.D.3
  • 14
    • 0036534143 scopus 로고    scopus 로고
    • Adjuvant therapy in rectal cancer: Analysis of stage, sex, and local control - Final report of Intergroup 0114
    • Tepper JE, O'Connell M, Niedzwiecki D, et al: Adjuvant therapy in rectal cancer: Analysis of stage, sex, and local control - Final report of Intergroup 0114. J Clin Oncol 20:1744-1750, 2002
    • (2002) J Clin Oncol , vol.20 , pp. 1744-1750
    • Tepper, J.E.1    O'Connell, M.2    Niedzwiecki, D.3
  • 15
    • 0001184602 scopus 로고    scopus 로고
    • Pre-operative therapy (PT) with oral uracil and tegafur (UFT) and concomitant irradiation (RT) in operable rectal cancer (RC): Preliminary results of a multicenter phase II study
    • abstr 590
    • Fernandez-Martos C, Aparicio J, Bosch C, et al: Pre-operative therapy (PT) with oral uracil and tegafur (UFT) and concomitant irradiation (RT) in operable rectal cancer (RC): Preliminary results of a multicenter phase II study. Proc Am Soc Clin Oncol 20:148a, 2001 (abstr 590)
    • (2001) Proc Am Soc Clin Oncol , vol.20
    • Fernandez-Martos, C.1    Aparicio, J.2    Bosch, C.3
  • 17
    • 0028402394 scopus 로고
    • Patterns of residual disease after pre-operative chemoradiation in ultrasound T3 rectal carcinoma
    • Meterissian S, Skibber J, Rich T, et al: Patterns of residual disease after pre-operative chemoradiation in ultrasound T3 rectal carcinoma. Ann Surg Oncol 1:111-116, 1994
    • (1994) Ann Surg Oncol , vol.1 , pp. 111-116
    • Meterissian, S.1    Skibber, J.2    Rich, T.3
  • 18
    • 0035916082 scopus 로고    scopus 로고
    • UFT plus oral leucovorin calcium (Orzel) and radiation in combined modality therapy: A comprehensive review
    • Minsky B: UFT plus oral leucovorin calcium (Orzel) and radiation in combined modality therapy: A comprehensive review. Int J Cancer 96:1-10, 2001
    • (2001) Int J Cancer , vol.96 , pp. 1-10
    • Minsky, B.1
  • 19
    • 0029966745 scopus 로고    scopus 로고
    • Phase I trials of uracil-tegafur (UFT) using 5 and 28 day administration schedules: Demonstration of schedule-dependent toxicities
    • Pazdur R, Lassere Y, Diaz-Canton E, et al: Phase I trials of uracil-tegafur (UFT) using 5 and 28 day administration schedules: Demonstration of schedule-dependent toxicities. Anticancer Drugs 7:728-733, 1996
    • (1996) Anticancer Drugs , vol.7 , pp. 728-733
    • Pazdur, R.1    Lassere, Y.2    Diaz-Canton, E.3
  • 20
    • 0032828168 scopus 로고    scopus 로고
    • Primary treatment of rectal cancer: Present and future
    • Minsky BD: Primary treatment of rectal cancer: Present and future. Crit Rev Oncol Hematol 32:19-30, 1999
    • (1999) Crit Rev Oncol Hematol , vol.32 , pp. 19-30
    • Minsky, B.D.1
  • 21
    • 0032850210 scopus 로고    scopus 로고
    • Phase II study of radiochemotherapy with UFT and low-dose oral leucovorin in patients with unresectable rectal cancer
    • de la Torre A, Ramos S, Valcarcel FJ, et al: Phase II study of radiochemotherapy with UFT and low-dose oral leucovorin in patients with unresectable rectal cancer. Int J Radiat Oncol Biol Phys 45:629-634, 1999
    • (1999) Int J Radiat Oncol Biol Phys , vol.45 , pp. 629-634
    • De La Torre, A.1    Ramos, S.2    Valcarcel, F.J.3
  • 22
    • 0035985283 scopus 로고    scopus 로고
    • Neoadjuvant therapy of rectal carcinoma with UFT-leucovorin plus radiotherapy
    • Feliu J, Calvilio J, Escribano A, et al: Neoadjuvant therapy of rectal carcinoma with UFT-leucovorin plus radiotherapy. Ann Oncol 13:730-736, 2002
    • (2002) Ann Oncol , vol.13 , pp. 730-736
    • Feliu, J.1    Calvilio, J.2    Escribano, A.3
  • 23
    • 0035975394 scopus 로고    scopus 로고
    • Pre-operative radiotherapy combined with total mesorectal excision for resectable rectal cancer
    • Kapiteijn E, Marijnen CA, Nagtegaal ID, et al: Pre-operative radiotherapy combined with total mesorectal excision for resectable rectal cancer. N Engl J Med 345:638-646, 2001
    • (2001) N Engl J Med , vol.345 , pp. 638-646
    • Kapiteijn, E.1    Marijnen, C.A.2    Nagtegaal, I.D.3
  • 24
    • 0030994521 scopus 로고    scopus 로고
    • Adjuvant post-operative fluorouracil-modulated chemotherapy combined with pelvic radiation therapy for rectal cancer: Initial results of Intergroup 0114
    • Tepper JE, O'Connell MJ, Petroni GR, et al: Adjuvant post-operative fluorouracil-modulated chemotherapy combined with pelvic radiation therapy for rectal cancer: Initial results of Intergroup 0114. J Clin Oncol 15:2030-2039, 1997
    • (1997) J Clin Oncol , vol.15 , pp. 2030-2039
    • Tepper, J.E.1    O'Connell, M.J.2    Petroni, G.R.3
  • 25
    • 0033064546 scopus 로고    scopus 로고
    • Prognostic implications of response to preoperative infusional chemoradiation in locally advanced rectal cancer
    • Janjan NA, Abbruzzese J, Pazdur R, et al: Prognostic implications of response to preoperative infusional chemoradiation in locally advanced rectal cancer. Radiother Oncol 51:153-160, 1999
    • (1999) Radiother Oncol , vol.51 , pp. 153-160
    • Janjan, N.A.1    Abbruzzese, J.2    Pazdur, R.3
  • 26
    • 0036644223 scopus 로고    scopus 로고
    • Does downstaging predict improved outcome after preoperative chemoradiation for extraperitoneal locally advanced rectal cancer? A long-term analysis of 165 patients
    • Valentini V, Coco C, Picciocchi A, et al: Does downstaging predict improved outcome after preoperative chemoradiation for extraperitoneal locally advanced rectal cancer? A long-term analysis of 165 patients. Int J Radiat Oncol Biol Phys 53:664-674, 2002
    • (2002) Int J Radiat Oncol Biol Phys , vol.53 , pp. 664-674
    • Valentini, V.1    Coco, C.2    Picciocchi, A.3
  • 27
    • 0037439583 scopus 로고    scopus 로고
    • Response to preoperative chemoradiation increases the use of sphincter-preserving surgery in patients with locally advanced low rectal carcinoma
    • Crane CH, Skibber JM, Feig BW, et al: Response to preoperative chemoradiation increases the use of sphincter-preserving surgery in patients with locally advanced low rectal carcinoma. Cancer 97:517-524, 2003
    • (2003) Cancer , vol.97 , pp. 517-524
    • Crane, C.H.1    Skibber, J.M.2    Feig, B.W.3
  • 28
    • 3042789321 scopus 로고    scopus 로고
    • Combined modality treatment with oxaliplatin, oral uracil and tegafur (UFT) and concomitant irradiation (RT) in rectal cancer: A dose-finding study
    • abstr 1293
    • Fernandez-Martos C, Aparicio, J, Bosch C, et al: Combined modality treatment with oxaliplatin, oral uracil and tegafur (UFT) and concomitant irradiation (RT) in rectal cancer: A dose-finding study. Proc Am Soc Clin Oncol 22:322, 2003 (abstr 1293)
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 322
    • Fernandez-Martos, C.1    Aparicio, J.2    Bosch, C.3
  • 29
    • 0041912759 scopus 로고    scopus 로고
    • Phase I/II trial of capecitabine, oxaliplatin, and radiation for rectal cancer
    • Rodel C, Grabenbauer GG, Papadopoulos T, et al: Phase I/II trial of capecitabine, oxaliplatin, and radiation for rectal cancer. J Clin Oncol 21:3098-3104, 2003
    • (2003) J Clin Oncol , vol.21 , pp. 3098-3104
    • Rodel, C.1    Grabenbauer, G.G.2    Papadopoulos, T.3
  • 30
    • 0347298702 scopus 로고    scopus 로고
    • Phase II trial of preoperative 3D conformal radiotherapy, protracted venous infusion 5-fluorouracil, and weekly CPT-11, followed by surgery for ultrasound-staged T3 rectal cancer
    • Mehta VK, Cho C, Ford JM, et al: Phase II trial of preoperative 3D conformal radiotherapy, protracted venous infusion 5-fluorouracil, and weekly CPT-11, followed by surgery for ultrasound-staged T3 rectal cancer. Int J Radiat Oncol Biol Phys 55:132-137, 2003
    • (2003) Int J Radiat Oncol Biol Phys , vol.55 , pp. 132-137
    • Mehta, V.K.1    Cho, C.2    Ford, J.M.3


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