Proliferating keratinocytes are putative sources of the psoriasis susceptibility-related EDA+ (extra domain A of fibronectin) oncofetal fibronectin

Journal of Investigative Dermatology

Volumn 123, Issue 3, 2004, Pages 537-546

  Széll, Márta ^a   Bata Csörgo, Zsuzsanna ^a   Koreck, Andrea ^a   Pivarcsi, Andor ^a   Polyánka, Hilda ^a   Szeg, Csilla ^a   Gaál, Magdolna ^a   Dobozy, Attila ^a   Kemény, Lajos ^a  

^a UNIVERSITY OF SZEGED   (Hungary)

Author keywords

Fibronectin alternative splicing; HaCaT cells; Non involved psoriatic epidermis; Psoriatic extracellular matrix environment

Indexed keywords

FIBRONECTIN;

ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; MITOSIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROCESSING; PSORIASIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 4143126760     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0022-202X.2004.23224.x     Document Type: Article

References (32)

1. Altankov G, Hecht J, Dimoudis N: Serum-free cultured keratinocytes fail to organize fibronectin matrix and possess different distribution of beta-1 integrins. Exp Dermatol 10:80-89, 2001
2. Bata-Csorgo Z, Cooper KD, Ting KM, Voorhees JJ, Hammerberg C: Fibronectin and alpha5 integrin regulate keratinocyte cell cycling. A mechanism for increased fibronectin potentiation of T cell lymphokine- driven keratinocyte hyperproliferation in psoriasis. J Clin Invest 101:1509-1518, 1998
3. Bata-Csorgo Z, Hammerberg C, Voorhees JJ, Cooper KD: Kinetics and regulation of human keratinocyte stem cell growth in short-term primary ex vivo culture. Cooperative growth factors from psoriatic lesional T lymphocytes stimulate proliferation among psoriatic uninvolved, but not normal, stem keratinocytes. J Clin Invest 95:317-327, 1995
4. Bhalerao J, Bowcock AM: The genetics of psoriasis: A complex disorder of the skin and immune system. Hum Mol Genet 7:1537-1545, 1998
5. Boukamp P, Petrussevska RT, Breitkreutz D, Hornung J, Markham A, Fusenig NE: Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J Cell Biol 106:761-771, 1988
6. Chen G, McCormick TS, Hammerberg C, Ryder-Diggs S, Stevens SR, Cooper KD: Basal keratinocytes from uninvolved psoriatic skin exhibit accelerated spreading and focal adhesion kinase responsiveness to fibronectin. J Invest Dermatol 117:1538-1545, 2001
7. Chen SH, Arany I, Apisarnthanarax N, et al: Response of keratinocytes from normal and psoriatic epidermis to interferon-gamma differs in the expression of zinc-alpha(2)-glycoprotein and cathepsin D. FASEB J 14:565-571, 2000
8. Cramer P, Caceres JF, Cazalla D, Kadener S, Muro AF, Baralle FE, Kornblihtt AR: Coupling of transcription with alternative splicing: RNA pol II promoters modulate SF2/ASF and 9G8 effects on an exonic splicing enhancer. Mol Cell 4:251-258, 1999
9. Diaz A, Jimenez SA: Interferon-gamma regulates collagen and fibronectin gene expression by transcriptional and post-transcriptional mechanisms. Int J Biochem Cell Biol 29:251-260, 1997
10. Fleischmajer R, Kuroda K, Hazan R, et al: Basement membrane alterations in psoriasis are accompanied by epidermal overexpression of MMP-2 and its inhibitor, TIMP-2. J Invest Dermatol 115:771-777, 2000
11. Gailit J, Rouslahti E: Regulation of the fibronectin receptor activity by divalent cations. J Biol Chem 263:12927-12932, 1987
12. Gratchev A, Guillot P, Hakiy N, Politz O, Orfanos CE, Schledzewski K, Goerdt S: Alternatively activated macrophages differentially express fibronectin and its splice variants and the extracellular matrix protein beta1G-H3. Scand J Immunol 53:386-392, 2001
13. Inoue T, Nabeshima K, Shimao Y, Koono M: Hepatocyte growth Factor/Scatter factor (HGF/SF) is a regulator of fibronectin splicing in MDCK cells: Comparison between the effects of HGF/SF and TGF-beta1 on fibronectin splicing at the EDA region. Biochem Biophys Res Commun 260: 225-231, 1999
14. Inoue T, Nabeshima K, Shimao Y, Meng JY, Koono M: Regulation of fibronectin expression and splicing in migrating epithelial cells: migrating MDCK cells produce a lesser amount of, but more active, fibronectin. Biochem Biophys Res Commun 280:1262-1268, 2001
15. Jackson M, Howie SE, Weller R, Sabin E, Hunter JA, McKenzie RC: Psoriatic keratinocytes show reduced IRF-1 and STAT-1alpha activation in response to gamma-IFN. FASEB J 13:495-502, 1999
16. Kadener S, Cramer P, Nogues G, et al: Antagonistic effects of T-Ag and VP16 reveal a role for RNA pol II elongation on alternative splicing. EMBO J 20:5759-5768, 2001
17. Kucich U, Rosenbloom JC, Shen G, Abrams WR, Hamilton AD, Sebti SM, Rosenbloom J: TGF-beta1 stimulation of fibronectin transcription in cultured lung fibroblasts requires active geranylgeranyl transferase I, psosphatidylcholine-specific phospholipase C, protein kinase C-delta, and p38, but not erk1/erk2. Arch Biochem Biophys 374:313-324, 2000
18. Kuo BA, Norton PA: Accurate selection of a 5′ splice site requires sequences within fibronectin alternative exon B. Nucleic Acids Res 27:3945-3952, 1999
19. Leivo T, Leivo I, Kariniemi AL, Keski-Oja J, Virtanen I: Down-regulation of transforming growth factor-beta receptors I and II is seen in lesional but not non-lesional psoriatic epidermis. Br J Dermatol 138:57-62, 1998
20. Li J, Tripathi BJ, Tripathi RC: Modulation of pre-mRNA splicing and protein production of fibronectin by TGF-beta2 in porcine trabecular cells. Invest Ophthalmol Vis Sci 41:3437-3443, 2000
21. Mondella MR, Magaudda L, Pergollizi S, et al: Behaviour of laminin 1 and type IV collagen in uninvolved psoriatic skin Immunohistochemical study using confocal laser scanning microscopy. Arch Dermatol Res 288:527-531, 1996
22. Oyama N, Iwatsuki K, Satoh M, Akiba H, Kaneko F: Dermal fibroblasts are one of the therapeutic targets for topical application of 1alpha,25- dihydroxyvitamin D3: The possible involvement of transforming growth factor-beta induction. Br J Dermatol 143:1140-1148, 2000
23. Pellegrini G, De Luca M, Orecchia G, et al: Expression, topography, and function of integrin receptors are severely altered in keratinocytes from involved and uninvolved psoriatic skin. J Clin Invest 89:1783-1795, 1992
24. Pivarcsi A, Szell M, Kemeny L, Dobozy A, Bata-Csorgo Z: Serum factors regulate the expression of the proliferation-related genes alpha5 integrin and keratin 1, but not keratin 10, in HaCaT keratinocytes. Arch Dermatol Res 293:20-213, 2001
25. Pollice AA, McCoy JP Jr, Shackney SE, et al: Sequential paraformaldehyde and methanol fixation for simultaneous flow cytometric analysis of DNA, cell surface proteins, and intracellular proteins. Cytometry 13:432-444, 1992
26. Raghow R, Gossage D, Kang AH: Pretranslational regulation of type I collagen, fibronectin, and a 50-kilodalton noncollagenous extracellular protein by dexamethasone in rat fibroblasts. J Biol Chem 261:4677-4684, 1986
27. - fibronectin is colocalized with CD11c+ cells at the dermal-epidermal junction in psoriatic tissue. J Invest Dermatol 114:864-864, 2000 (Abstract)
28. Ryle CM, Breitkreutz D, Stark HJ, Leigh IM, Steinert PM, Roop D, Fusenig NE: Density-dependent modulation of synthesis of keratin 1 and 10 in human keratinocyte line HACAT and in ras-transfected tumorigenic clones. Differentiation 40:42-54, 1989
29. Sticht H, Pickford AR, Potts JR, Campbell ID: Solution structure of the glycosylated second type 2 module of fibronectin. J Mol Biol 276:177-187, 1998
30. Ting KM, Rothaupt D, McCormick TS, et al: Overexpression of the oncofetal Fn variant containing the EDA splice-in segment in the dermal-epidermal junction of psoriatic uninvolved skin. J Invest Dermatol 114:706-711, 2000
31. Vaccaro M, Magaudda L, Cutroneo G, Trimarchi F, Guarneri F, Guarneri B: Changes in the distribution of laminin alpha1 chain in psoriatic skin: Immunohistochemical study using confocal laser scanning microscopy. Br J Dermatol 146:392-398, 2002
32. Wataya-Kaneda M, Hashimoto K, Kato M, Miyazono K, Yoshikawa K: Differential localization of TGF-beta-precursor isotypes in psoriatic human skin. J Dermatol Sci 11:183-188, 1996