Synthesis and activity of 2-[4-(4-[ 3H]-2-cyanophenyl) piperazinyl]-N-(2,4,6-[ 3H] 3-3-methylphenyl)acetamide: A selective dopamine D 4 receptor agonist and radioligand

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 20, 2004, Pages 5095-5098

  Matulenko, Mark A ^a   Surber, Bruce ^a   Fan, Leimin ^a   Kolasa, Teodozyi ^a   Nakane, Masaki ^a   Terranova, Marc A ^a   Uchic, Marie E ^a   Miller, Loan N ^a   Chang, Renjie ^a   Donnelly Roberts, Diana L ^a   Namovic, Marian T ^a   Moreland, Robert B ^a   Brioni, Jorge D ^a   Stewart, Andrew O ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

Agonist; Dopamine; Radioligand

Indexed keywords

ACETAMIDE DERIVATIVE; DOPAMINE 4 RECEPTOR STIMULATING AGENT; DOPAMINE RECEPTOR STIMULATING AGENT; RADIOLIGAND; TRITIUM; UNCLASSIFIED DRUG;

ARTICLE; BROMINATION; CHEMICAL PROCEDURES; CHEMICAL REACTION; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; STRUCTURE ACTIVITY RELATION;

ACETAMIDES; CELL LINE; HUMANS; LIGANDS; PIPERAZINES; RADIOLIGAND ASSAY; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D4; STRUCTURE-ACTIVITY RELATIONSHIP; TRITIUM;

TRITIUM;

EID: 4143120792     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.07.068     Document Type: Article

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